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Sleep apnea and women

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https://www.readbyqxmd.com/read/28429850/association-of-obstructive-sleep-apnea-with-arterial-stiffness-and-nondipping-blood-pressure-in-patients-with-hypertension
#1
Raimundo Jenner, Fernanda Fatureto-Borges, Valéria Costa-Hong, Heno F Lopes, Sandra H Teixeira, Elias Marum, Dante A M Giorgi, Fernanda M Consolim-Colombo, Luiz A Bortolotto, Geraldo Lorenzi-Filho, Eduardo M Krieger, Luciano F Drager
Whether sex influences the association of obstructive sleep apnea (OSA) with markers of cardiovascular risk in patients with hypertension is unknown. In this study, 95 hypertensive participants underwent carotid-femoral pulse wave velocity, 24-hour ambulatory blood pressure monitoring, echocardiogram, and polysomnography after a 30-day standardized treatment with hydrochlorothiazide plus enalapril or losartan. OSA was present in 52 patients. Compared with non-OSA patients, pulse wave velocity values were higher in the OSA group (men: 11...
April 21, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28365841/assessing-the-likelihood-of-obstructive-sleep-apnea-a-comparison-of-nine-screening-questionnaires
#2
Kuruswamy Thurai Prasad, Inderpaul Singh Sehgal, Ritesh Agarwal, Ashutosh Nath Aggarwal, Digambar Behera, Sahajal Dhooria
PURPOSE: Several questionnaires are available for the screening of obstructive sleep apnea (OSA). Herein, we compare the performance characteristics of nine available questionnaires for assessing the likelihood of OSA. METHODS: Consecutive subjects who underwent polysomnography at the sleep laboratory of the unit were included. Subjects with obstructive events and apnea hypopnea index (AHI) ≥5 were considered to have OSA. The likelihood ratios (LRs) and other performance characteristics were calculated for the following nine questionnaires: Berlin, modified Berlin, STOP, STOP-Bang and OSA50 questionnaires, sleep apnea clinical score (SACS), Epworth sleepiness scale (ESS), American Society of Anesthesiologists (ASA) checklist, and the elbow sign questionnaire...
April 1, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28364463/change-in-job-strain-as-a-predictor-of-change-in-insomnia-symptoms-analyzing-observational-data-as-a-non-randomized-pseudo-trial
#3
Jaana I Halonen, Tea Lallukka, Jaana Pentti, Sari Stenholm, Naja H Rod, Marianna Virtanen, Paula Salo, Mika Kivimäki, Jussi Vahtera
Study objectives: To examine whether change in job strain leads to change in insomnia symptoms. Methods: Among 24873 adults (82% women, mean age 44 years) who participated in a minimum of three consecutive study waves (2000-2012), job strain was assessed at the first and second wave and insomnia symptoms at all three waves. We analyzed observational data as a "pseudo-trial" including participants with no job strain in the first wave and no insomnia symptoms in the first and second wave (n = 7354) to examine whether the onset of job strain between the first and second waves predicted the onset of insomnia symptoms in the third wave...
January 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364416/periodic-limb-movements-during-sleep-mimicking-rem-sleep-behavior-disorder-a-new-form-of-periodic-limb-movement-disorder
#4
Carles Gaig, Alex Iranzo, Montserrat Pujol, Hernando Perez, Joan Santamaria
Study Objectives: To describe a group of patients referred because of abnormal sleep behaviors that were suggestive of rapid eye movement (REM) sleep behavior disorder (RBD) in whom video-polysomnography ruled out RBD and showed the reported behaviors associated with vigorous periodic limb movements during sleep (PLMS). Aims and Methods: Clinical history and video-polysomnography review of patients identified during routine visits in a sleep center. Results: Patients were 15 men and 2 women with a median age of 66 (range: 48-77) years...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28356180/nocturnal-desaturation-is-associated-with-atrial-fibrillation-in-patients-with-ischemic-stroke-and-obstructive-sleep-apnea
#5
Chung-Yao Chen, Chien-Hui Ho, Chia-Ling Chen, Chung-Chieh Yu
STUDY OBJECTIVES: Both atrial fibrillation (AF) and obstructive sleep apnea (OSA) are risk factors for ischemic stroke. Previous studies suggested that OSA is associated with AF in individuals who have not had a stroke. For better secondary prevention of stroke, this study determined the association between OSA and AF among patients with ischemic stroke. METHODS: This cross-sectional study recruited consecutive patients with subacute ischemic stroke admitted for neurorehabilitation...
March 14, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28352476/cpap-treatment-adherence-in-women-with-obstructive-sleep-apnea
#6
E Libman, S Bailes, C S Fichten, D Rizzo, L Creti, M Baltzan, R Grad, A Pavilanis, D-L Tran, K Conrod, R Amsel
Untreated obstructive sleep apnea (OSA) has numerous negative health-related consequences. Continuous positive airway pressure (CPAP) is generally considered the treatment of choice for OSA, but rates of nonadherence are high. It is believed that OSA is more prevalent among men; therefore understanding how OSA presents among women is limited and treatment adherence has received little research attention. For this study, 29 women were recruited from primary care offices. They completed a questionnaire battery and underwent a night of nocturnal polysomnography (PSG) followed by a visit with a sleep specialist...
2017: Sleep Disorders
https://www.readbyqxmd.com/read/28346149/sleep-health-of-australian-adults-in-2016-results-of-the-2016-sleep-health-foundation-national-survey
#7
Robert J Adams, Sarah L Appleton, Anne W Taylor, Tiffany K Gill, Carol Lang, R Douglas McEvoy, Nick A Antic
OBJECTIVE: To measure the prevalence and social impacts of sleep problems in Australia. DESIGN: Cross-sectional national adult online survey. SETTING: Community-based sample. PARTICIPANTS: Australian adults ≥18 years, n=1011. RESULTS: Self-reported inadequate sleep, of either duration or quality, and its daytime consequences affect 33%-45% of adults. Diagnosed sleep apnea is reported by 8%, significant insomnia by 20%, and restless legs by18% of adults...
February 2017: Sleep Health
https://www.readbyqxmd.com/read/28334763/the-challenge-of-identifying-family-medicine-patients-with-obstructive-sleep-apnea-addressing-the-question-of-gender-inequality
#8
Sally Bailes, Catherine S Fichten, Dorrie Rizzo, Marc Baltzan, Roland Grad, Alan Pavilanis, Laura Creti, Rhonda Amsel, Eva Libman
Purpose.: The purpose of this study was to examine the sleep characteristics, metabolic syndrome disease and likelihood of obstructive sleep apnea in a sample of older, family medicine patients previously unsuspected for sleep apnea. Methods.: A total of 295 participants, minimum age 45, 58.7% women, were recruited from two family medicine clinics. None previously had been referred for sleep apnea testing. All participants completed a sleep symptom questionnaire and were offered an overnight polysomnography study, regardless of questionnaire results...
February 23, 2017: Family Practice
https://www.readbyqxmd.com/read/28306414/cross-sectional-comparison-of-sleep-disordered-breathing-in-native-peruvian-highlanders-and-lowlanders
#9
Luu V Pham, Christopher Meinzen, Rafael S Arias, Noah G Schwartz, Adi Rattner, Catherine H Miele, Philip L Smith, Hartmut Schneider, J Jaime Miranda, Robert H Gilman, Vsevolod Y Polotsky, William Checkley, Alan R Schwartz
Pham, Luu V., Christopher Meinzen, Rafael S. Arias, Noah G. Schwartz, Adi Rattner, Catherine H. Miele, Philip L. Smith, Hartmut Schneider, J. Jaime Miranda, Robert H. Gilman, Vsevolod Y. Polotsky, William Checkley, and Alan R. Schwartz. Cross-sectional comparison of sleep-disordered breathing in native Peruvian highlanders and lowlanders. High Alt Med Biol. 18:11-19, 2017. BACKGROUND: Altitude can accentuate sleep disordered breathing (SDB), which has been linked to cardiovascular and metabolic diseases...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28300571/sleep-apnea-and-hypertension-are-there-gender-differences-the-vitoria-sleep-cohort
#10
Irene Cano-Pumarega, Ferrán Barbé, Andrés Esteban, Montserrat Martínez-Alonso, Carlos Egea, Joaquín Durán-Cantolla
BACKGROUND: Evidence from longitudinal studies has reported contradictory results regarding the association between obstructive sleep apnea (OSA) and hypertension. In a previous analysis of the Vitoria Sleep Cohort, we evaluated the relationship between OSA and the risk of developing hypertension and we did not find an independent association after adjustment for confounding factors. In the present study, we perform a post hoc analysis to assess the association between OSA and incident stage 2 hypertension (systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 100 mmHg) based on gender differences...
March 11, 2017: Chest
https://www.readbyqxmd.com/read/28293491/disparities-in-utilization-of-jaw-surgery-for-treatment-of-sleep-apnea-a-nationwide-analysis
#11
Ravi K Garg, Ying Shan, Jeffrey A Havlena, Ahmed M Afifi
BACKGROUND: Maxillomandibular advancement has been shown to be one of the most effective operations for management of severe obstructive sleep apnea, yet pharyngeal surgery is more commonly performed. The goal of this study was to identify socioeconomic factors associated with this phenomenon. METHODS: Patients aged 14 or older with a primary hospital diagnosis of sleep apnea were identified using the National Inpatient Sample from 2005 to 2012. ICD9 codes were used to determine whether a pharyngeal or jaw procedure was performed...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28258728/relation-of-obstructive-sleep-apnea-and-a-common-variant-at-chromosome-4q25-to-atrial-fibrillation
#12
Neel J Patel, Quinn S Wells, Shi Huang, Raghu P Upender, Dawood Darbar, Ken Monahan
Obstructive sleep apnea (OSA) and single nucleotide polymorphisms (SNPs) at the 4q25 locus are associated with increased risk of atrial fibrillation (AF). Whether these associations are independent of traditional risk factors for AF remains unknown. Using billing code queries and manual chart review, we assembled a cohort of adults that underwent overnight polysomnography and at least 1 12-lead electrocardiogram. Case status was defined by electrocardiographic data in support of AF or documentation of AF by a staff cardiologist...
May 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28253389/technique-and-preliminary-analysis-of-drug-induced-sleep-endoscopy-with-online-polygraphic-cardiorespiratory-monitoring-in-patients-with-obstructive-sleep-apnea-syndrome
#13
Riccardo Gobbi, Simone Baiardi, Susanna Mondini, Luca Cerritelli, Ottavio Piccin, Giuseppe Scaramuzzino, Francesca Milano, Maria Rita Melotti, Francesco Mordini, Antonio Pirodda, Fabio Cirignotta, Giovanni Sorrenti
Importance: Drug-induced sleep endoscopy is a diagnostic technique that allows dynamic evaluation of the upper airway during artificial sleep. The lack of a standardized procedure and the difficulties associated with direct visual detection of obstructive events result in poor intraobserver and interobserver reliability, especially when otolaryngology surgeons not experienced in the technique are involved. Objectives: To describe a drug-induced sleep endoscopy technique implemented with simultaneous polygraphic monitoring of cardiorespiratory parameters (DISE-PG) in patients with a diagnosis of obstructive sleep apnea syndrome and discuss the technique's possible advantages compared with the standard procedure...
March 2, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28236270/oxidative-and-carbonyl-stress-in-pregnant-women-with-obstructive-sleep-apnea
#14
Nazia Khan, Geralyn Lambert-Messerlian, Joao Filipe Monteiro, Julius Hodosy, Ľubomíra Tóthová, Peter Celec, Elizabeth Eklund, Patrizia Curran, Ghada Bourjeily
PURPOSE: Pregnant women are particularly susceptible to sleep-disordered breathing. Obstructive sleep apnea (OSA) in pregnancy is associated with poor pregnancy and fetal outcomes. Oxidative stress caused by intermittent hypoxemia and reoxygenation may impact pregnancy health. We hypothesize that pregnant women with OSA have a pronounced oxidative stress profile. METHODS: A case-control study was performed to study oxidative stress markers in the serum of pregnant women with or without OSA...
February 24, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28231365/alteration-of-serum-levels-of-inflammatory-cytokines-and-polysomnographic-indices-after-uvulopalatal-flap-surgery-in-obstructive-sleep-apnea
#15
Murad Mutlu, Erkan Vuralkan, Istemihan Akin, Hikmet Firat, Sadik Ardic, Sevgi Akaydin, Ece Miser
The aim of the current study was to compare the changes in polysomnographic indices and serum levels of C-reactive protein (CRP), cystatin C, tumor necrosis factor-α (TNF-α), and intercellular adhesion molecule-1 (ICAM-1) in patients with obstructive sleep apnea (OSA) who were treated surgically via a uvulopalatal flap (UPF) technique. Twenty-five patients (14 men, 11 women), average age 46.2 ± 9.3 years, who underwent UPF surgery were included in this study. Serum biochemical analyses and polysomnographic examinations were performed before and 6 months after the surgery...
February 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28197893/gender-differences-in-clinical-and-polysomnographic-features-of-obstructive-sleep-apnea-a-clinical-study-of-2827-patients
#16
Ozen K Basoglu, Mehmet Sezai Tasbakan
PURPOSE: Obstructive sleep apnea (OSA) is underdiagnosed in females due to different clinical presentation. We aimed to determine the effect of gender on clinical and polysomnographic features and identify predictors of OSA in women. METHODS: Differences in demographic, clinical, and polysomnographic parameters between 2052 male and 775 female OSA patients were compared. RESULTS: In female OSA patients, age (56.1 ± 9.7 vs. 50.4 ± 11...
February 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28185010/evaluation-of-effects-of-anterior-palatoplasty-operation-on-upper-airway-parameters-in-computed-tomography-in-patients-with-pure-snoring-and-obstructive-sleep-apnea-syndrome
#17
Adin Selcuk, Tulay Ozer, Erkan Esen, Fatih Ozdogan, Halil Erdem Ozel, Turgut Yuce, Sebla Caliskan, Sinem Dasli, Nagihan Bilal, Gulden Genc, Selahattin Genc
AIM: To investigate changes in upper airway volume parameters measured by computerized tomography scans in patients with surgically treated by anterior palatoplasty of whom having pure snoring and mild-moderate obstructive sleep apnea. METHOD: A prospective study on consecutively anterior palatoplasty performed pure snoring and obstructive sleep apnea patients. Computerized tomography scans were obtained preoperatively and following anterior palatoplasty procedure to measure changes in upper airway volume...
February 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28134311/prevalence-and-predictors-of-atherogenic-serum-lipoprotein-dyslipidemia-in-women-with-obstructive-sleep-apnea
#18
Yunyan Xia, Yiqun Fu, Yuyu Wang, Yingjun Qian, Xinyi Li, Huajun Xu, Jianyin Zou, Jian Guan, Hongliang Yi, Lili Meng, Xulan Tang, Huaming Zhu, Dongzhen Yu, Huiqun Zhou, Kaiming Su, Shankai Yin
Obstructive sleep apnea (OSA) is associated with dyslipidemia. However, no study has focused on dyslipidemia in women with OSA. The aim of this study was to determine the prevalence and risk factors for dyslipidemia in women with OSA. Between 2007 and 2013, 570 eligible female patients with suspected OSA were consecutively recruited. The analyzed data consisted of polysomnography parameters, biochemical indicators, and anthropometric measurements. Serum lipid levels and dyslipidemia were compared. Binary logistic regression and multivariate linear regression models were used to determine the independent risk factors influencing serum lipids...
January 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28123647/phenotypic-contrasts-of-duchenne-muscular-dystrophy-in-women-two-case-reports
#19
Karen T Nozoe, Ricardo T Akamine, Diego R Mazzotti, Daniel N Polesel, Luís F Grossklauss, Sergio Tufik, Monica L Andersen, Gustavo A Moreira
We discussed two cases of symptomatic female carriers to Duchenne Muscular Dystrophy. The first case is a 20 year-old girl with classical phenotypic manifestation of the disease, similar to the condition in boys. The case 2 is a 62 year-old woman with progressive muscular weakness. The disease is much less common in woman than men so both cases described here are considered rare forms of the disease, with several clinical implications. In both cases, a progressive muscle weakness, impairment in walking and sleeping was observed, in addition to obstructive sleep apnea syndrome and alveolar hypoventilation, that required noninvasive ventilatory support...
July 2016: Sleep Science
https://www.readbyqxmd.com/read/28121644/peripartum-management-of-obstructive-sleep-apnea
#20
Jessica M Booth, Ashley M Tonidandel
The prevalence of obstructive sleep apnea is unknown during pregnancy, but the syndrome is likely underdiagnosed and rising in frequency along with the obesity epidemic. Obstructive sleep apnea is associated with adverse outcomes, including hypertensive disorders of pregnancy, gestational diabetes, preterm, and cesarean delivery. Obese pregnant women should be screened and referred to a sleep medicine specialist for evaluation. Continuous positive airway pressure is the treatment of choice with demonstrated safety and compliance in pregnancy...
June 2017: Clinical Obstetrics and Gynecology
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