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https://www.readbyqxmd.com/read/29454501/postoperative-inflammation-and-insulin-resistance-in-relation-to-body-composition-adiposity-and-carbohydrate-treatment-a-randomised-controlled-study
#1
Nilanjana Tewari, Sherif Awad, František Duška, Julian P Williams, Andrew Bennett, Ian A Macdonald, Dileep N Lobo
BACKGROUND & AIMS: The aims of this study were to identify whether differences in distribution of adipose tissue and skeletal muscle in obese and non-obese individuals contribute to the magnitude of the postoperative inflammatory response and insulin resistance, with and without preoperative treatment with carbohydrate drinks. METHODS: Thirty-two adults (16 obese/16 non-obese) undergoing elective major open abdominal surgery participated in this 2 × 2 factorial, randomised, double-blind, placebo-controlled study...
February 14, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29451068/increased-visceral-adipose-tissue-and-altered-adiposity-distribution-in-premenopausal-lupus-patients-correlation-with-cardiovascular-risk-factors
#2
L P C Seguro, J A Paupitz, V F Caparbo, E Bonfa, R M R Pereira
Objective Visceral adipose tissue (VAT) correlates with cardiovascular risk factors and has never been assessed in systemic lupus erythematosus (SLE). Our aim was to evaluate VAT in premenopausal SLE patients. Methods Sixty-three premenopausal SLE patients and 186 age-matched healthy women were included. Demographic, anthropometric, disease and treatment parameters were evaluated. VAT was measured by dual X-ray absorptiometry (DXA) with APEX 4.0 software. Results SLE patients had a disease duration of 5.25 ± 3...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29446645/the-relationship-of-perivascular-adipose-tissue-and-atherosclerosis-in-the-aorta-and-carotid-arteries-determined-by-magnetic-resonance-imaging
#3
Mohammad Alkhalil, Evan Edmond, Laurienne Edgar, Janet E Digby, Omar Omar, Matthew D Robson, Robin P Choudhury
BACKGROUND AND AIMS: Imaging studies have relied on the 'overall' volumetric quantification of perivascular adipose tissue. We sought to assess the relationship of circumferential distribution between perivascular adipose tissue and adjacent wall thickness of carotid and aortic arteries using dedicated magnetic resonance imaging sequences. METHODS: Vessel wall and perivascular adipose tissue were acquired using magnetic resonance imaging (1.5 T). Co-registered images were segmented separately, and measurements of both perivascular adipose tissue and vessel wall were obtained along radii of the vessel spaced at angles of 5° each...
February 1, 2018: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29445913/dietary-pattern-associated-with-selenoprotein-p-and-mri-derived-body-fat-volumes-liver-signal-intensity-and-metabolic-disorders
#4
Romina di Giuseppe, Sandra Plachta-Danielzik, Manja Koch, Ute Nöthlings, Sabrina Schlesinger, Jan Borggrefe, Marcus Both, Hans-Peter Müller, Jan Kassubek, Gunnar Jacobs, Wolfgang Lieb
PURPOSE: The association of complex dietary patterns with circulating selenoprotein P (SELENOP) levels in humans is unknown. In a general population sample, we aimed to identify a dietary pattern explaining inter-individual variation in circulating SELENOP concentrations and to study this pattern in relation to prevalent diabetes, metabolic syndrome (MetS), MRI-determined total volumes of visceral (VAT) and subcutaneous (SAT) abdominal adipose tissue, and liver signal intensity/fatty liver disease...
February 14, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29443833/experimental-study-on-effects-of-adipose-derived-stem-cell-seeded-silk-fibroin-chitosan-film-on-wound-healing-of-a-diabetic-rat-model
#5
Yan-Yun Wu, Yan-Peng Jiao, Li-Ling Xiao, Min-Min Li, Hong-Wei Liu, Sheng-Hong Li, Xuan Liao, Yong-Tian Chen, Jiang-Xuan Li, Yang Zhang
BACKGROUND: Wound healing is a complex process that relies on growth factors and stimulation of angiogenesis. Tissue engineering materials composed of adipose-derived stem cells (ADSCs) and silk fibroin (SF)/chitosan (CS) may be able to solve this problem. The aim of this study was to investigate the wound-healing potential of ADSC-seeded SF/CS in streptozotocin-induced diabetic rats. MATERIALS AND METHODS: Thirty-six male Sprague-Dawley rats were purchased and randomly assigned into 3 groups: a control group (no graft), a group treated with SF/CS film graft, and a group treated with ADSC-seeded SF/CS graft...
February 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29439189/socioeconomic-inequality-in-recovery-from-poor-physical-and-mental-health-in-mid-life-and-early-old-age-prospective-whitehall-ii-cohort-study
#6
REVIEW
Akihiro Tanaka, Martin J Shipley, Catherine A Welch, Nora E Groce, Michael G Marmot, Mika Kivimaki, Archana Singh-Manoux, Eric J Brunner
BACKGROUND: Few studies have examined the influence of socioeconomic status on recovery from poor physical and mental health. METHODS: Prospective study with four consecutive periods of follow-up (1991-2011) of 7564 civil servants (2228 women) recruited while working in London. Health was measured by the Short-Form 36 questionnaire physical and mental component scores assessed at beginning and end of each of four rounds. Poor health was defined by a score in the lowest 20% of the age-sex-specific distribution...
February 8, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29437161/associations-of-adult-genetic-risk-scores-for-adiposity-with-childhood-abdominal-liver-and-pericardial-fat-assessed-by-magnetic-resonance-imaging
#7
C Monnereau, S Santos, A van der Lugt, V W V Jaddoe, J F Felix
BACKGROUND: Genome-wide association studies (GWASs) identified single-nucleotide polymorphisms (SNPs) involved in adult fat distribution. Whether these SNPs also affect abdominal and organ-specific fat accumulation in children is unknown. METHODS: In a population-based prospective cohort study among 1995 children (median age: 9.8 years, 95% range 9.4-10.8), we tested the associations of six genetic risk scores based on previously identified SNPs for childhood body mass index (BMI), adult BMI, liver fat, waist-hip ratio, pericardial fat mass, visceral and subcutaneous adipose tissue ratio (VAT/SAT ratio) and four individual SAT- and VAT-associated SNPs for association with SAT (N=1746), VAT (N=1742), VAT/SAT ratio (N=1738), liver fat fraction (N=1950) and pericardial fat mass (N=1803) measured by magnetic resonance imaging...
December 7, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29431910/lipomatoses
#8
Philipp Al Ghazal, Lisa-Lena Grönemeyer, Michael P Schön
Lipomatoses are benign proliferations of adipose tissue, often with typical distribution patterns, which usually occur without clear causes. In contrast to circumscribed lipomas, they develop diffusely and symmetrically and are not surrounded by a fibrous pseudocapsule. The most common form is benign symmetric lipomatosis (BSL; Launois-Bensaude syndrome), of which four types are distinguished based on the distribution pattern of hyperplastic adipose tissue. The etiology and pathogenesis of the disease are still largely unknown, although some forms appear to have a hereditary basis or to be associated with increased alcohol consumption...
February 12, 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29429159/-retroperitoneal-dedifferentiated-liposarcoma-with-rhabdomyoblastic-differentiation-a-clinicopathological-analysis
#9
L Liu, L H Wang, Y B Ren, X S Rao, S M Yang
Objective: To investigate the clinicopathological features, differential diagnosis, treatment and prognosis of dedifferentiated liposarcoma with rhabdomyoblastic differentiation. Methods: Six cases of retroperitoneal dedifferentiated liposarcoma with rhabdomyoblastic features were collected from December 2014 to August 2017 at Peking University International Hospital. The clinical manifestations, histomorphology, immunophenotype, treatment and follow-up data were analyzed, and relevant literature reviewed. Results: The six patients included two males and four females, with age range of 47 to 66 years (mean 56 years)...
February 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29425375/impact-of-hypothermic-stress-during-special-operations-training-of-chilean-military-forces
#10
Claudio Nieto Jimenez, Jorge Cajigal Vargas, Vjera Sofia Triantafilo Vladilo, Jose Naranjo Orellana
Introduction: The Chilean Army considers processes that can optimize physical capacities for responding to the impact of situations and given stressors. The study of the effect of hypothermia as a stressor agent (HSA) and its relationship with cardiovascular, hematological, anthropometric, endocrine, and immunological parameters has not been fully addressed experimentally in military populations. Objective: To identify the endocrine, hematological, cardiovascular, and immunological changes caused by HSA and to associate these variables with body composition and physical fitness in the military special operation courses of the Chilean Army...
February 7, 2018: Military Medicine
https://www.readbyqxmd.com/read/29423731/hiv-persistence-in-adipose-tissue-reservoirs
#11
REVIEW
Jacob Couturier, Dorothy E Lewis
PURPOSE OF REVIEW: The purpose of this review is to examine the evidence describing adipose tissue as a reservoir for HIV-1 and how this often expansive anatomic compartment contributes to HIV persistence. RECENT FINDINGS: Memory CD4 T cells and macrophages, the major host cells for HIV, accumulate in adipose tissue during HIV/SIV infection of humans and rhesus macaques. Whereas HIV and SIV proviral DNA is detectable in CD4 T cells of multiple fat depots in virtually all infected humans and monkeys examined, viral RNA is less frequently detected, and infected macrophages may be less prevalent in adipose tissue...
February 9, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29422959/implication-of-atypical-supraclavicular-f18-fluorodeoxyglucose-uptake-in-patients-with-breast-cancer-association-between-brown-adipose-tissue-and-breast-cancer
#12
Takaaki Fujii, Reina Yajima, Hironori Tatsuki, Katsuya Oosone, Hiroyuki Kuwano
It has been reported that F18-fluorodeoxyglucose (FDG) uptake in the neck and supraclavicular lesions represents activated brown adipose tissue (BAT). In the present study, the association between BAT activity, detected by FDG-positron emission tomography (PET), and the clinicopathological features of patients with breast cancer was investigated. The cases of 156 consecutive patients with breast cancer who underwent FDG-PET preoperatively were analyzed. The distribution and intensity of atypical FDG uptake in the neck and/or supraclavicular region was reviewed...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29416771/menopause-and-adipose-tissue-mir-19a-3p-is-sensitive-to-hormonal-replacement
#13
Reeta Kangas, Cristina Morsiani, Grazia Pizza, Catia Lanzarini, Pauliina Aukee, Jaakko Kaprio, Sarianna Sipilä, Claudio Franceschi, Vuokko Kovanen, Eija K Laakkonen, Miriam Capri
Tissue-specific effects of 17β-estradiol are delivered via both estrogen receptors and microRNAs (miRs). Menopause is known to affect the whole-body fat distribution in women. This investigation aimed at identifying menopause- and hormone replacement therapy (HRT)-associated miR profiles and miR targets in subcutaneous abdominal adipose tissue and serum from the same women. A discovery phase using array technology was performed in 13 women, including monozygotic twin pairs discordant for HRT and premenopausal young controls...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29415997/downregulation-of-%C3%AE-1-4-galactosyltransferase-5-improves-insulin-resistance-by-promoting-adipocyte-commitment-and-reducing-inflammation
#14
Shu-Fen Li, Cui-Song Zhu, Yu-Meng Wang, Xin-Xin Xie, Liu-Ling Xiao, Zhi-Chun Zhang, Qi-Qun Tang, Xi Li
Protein glycosylation is an important post-translational modification. Aberrant glycosylation has been implicated in many diseases because of associated changes in protein distribution and biological function. We showed that the expression of β1, 4-galactosyltransferase 5 (B4GalT5) was positively correlated with diabetes and obesity. In vivo, B4GalT5 knockdown in subcutaneous adipose tissue alleviated insulin resistance and adipose tissue inflammation, and increased adipogenesis in high-fat diet (HFD)-fed mice and ob/ob mice...
February 7, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29415242/a-single-blind-study-evaluating-the-efficacy-of-gold-nanoparticle-photothermal-assisted-liposuction-in-an-ex-vivo-human-tissue-model
#15
Wangzhong Sheng, William J Seare, Barry DiBernardo, Ali H Alhasan, Esther Cory, Paul Chasan, Robert L Sah, Khalid M Almutairi, Adah Almutairi
Background: Liposuction is one of the most performed cosmetic surgery procedures. In a previously reported study, gold-nanoparticle (GNP) laser-assisted liposuction (NanoLipo) was shown to improve procedure parameters and outcomes in a porcine model. Objective: An ex vivo human liposuction model was developed to assess the ease, efficacy, and outcomes of NanoLipo, and to further explore its mechanism of action in facilitating liposuction. Methods: NanoLipo was compared to a Control without GNPs in sets of fresh, non-perfused, anatomically-symmetric, matched tissue specimens from 12 patients...
February 3, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29404801/correction-to-association-of-adiposity-with-hemoglobin-levels-in-patients-with-chronic-kidney-disease-not-on-dialysis
#16
Hirokazu Honda, Kota Ono, Tadao Akizawa, Kosaku Nitta, Akira Hishida
The article Association of adiposity with hemoglobin levels in patients with chronic kidney disease not on dialysis, written by Hirokazu Honda, Kota Ono, Tadao Akizawa, Kosaku Nitta and Akira Hishida, was originally published electronically on the publisher's internet portal (currently springerlink) on November 4, 2017 without open access. With the author(s)' decision to opt for Open Choice, the copyright of the article changed on February 6, 2018 to © The Author(s) [2017] and the article is forthwith distributed under the terms of the Creative Commons Attribution 4...
February 6, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29401461/body-fat-distribution-and-risk-of-incident-ischemic-stroke-in-men-and-women-aged-50-to-74-years-from-the-general-population-the-kora-augsburg-cohort-study
#17
Karl Zahn, Jakob Linseisen, Margit Heier, Annette Peters, Barbara Thorand, Franziska Nairz, Christa Meisinger
BACKGROUND: It remains controversial whether measures of general or abdominal adiposity are better risk predictors for ischemic stroke. Furthermore, so far it is unclear whether body fat mass index (BFMI) and fat free mass index (FFMI) are risk predictors for ischemic stroke. This study examined the sex-specific relevance of body mass index (BMI), BROCA Index, waist circumference (WC), waist-height ratio (WHtR), BFMI and FFMI for the development of ischemic stroke in a Caucasian population...
2018: PloS One
https://www.readbyqxmd.com/read/29398370/depot-specific-and-gh-dependent-regulation-of-igf-binding-protein-4-pregnancy-associated-plasma-protein-a-and-stanniocalcin-2-in-murine-adipose-tissue
#18
Rikke Hjortebjerg, Darlene E Berryman, Ross Comisford, Edward O List, Claus Oxvig, Mette Bjerre, Jan Frystyk, John J Kopchick
INTRODUCTION: Pregnancy-associated plasma protein-A (PAPP-A) stimulates insulin-like growth factor (IGF)-I action through proteolytic cleavage of IGF binding protein-4 (IGFBP-4). Recently, stanniocalcin-2 (STC2) was discovered as an inhibitor of PAPP-A. Most members of the IGF system are expressed in adipose tissue (AT), but there is a relative paucity of information on the distribution of IGFBP-4, PAPP-A, and STC2 in different AT depots. Since IGF-I expression in AT is highly GH-dependent, we used bovine GH transgenic (bGH) and GH receptor knockout (GHR-/-) mice to investigate AT depot-specific expression patterns of IGFBP-4, PAPP-A, and STC2, and whether the regulation is GH-dependent...
February 2, 2018: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/29397797/tissue-sterol-composition-in-atlantic-salmon-salmo-salar-l-depends-on-the-dietary-cholesterol-content-and-on-the-dietary-phytosterol-cholesterol-ratio-but-not-on-the-dietary-phytosterol-content
#19
Nini H Sissener, Grethe Rosenlund, Ingunn Stubhaug, Nina S Liland
The aim of the study was to investigate how the dietary sterol composition, including cholesterol, phytosterol:cholesterol ratio and phytosterols, affect the absorption, biliary excretion, retention, tissue storage and distribution of cholesterol and individual phytosterols in Atlantic salmon (Salmo salar L.). A feeding trial was conducted at two different temperatures (6 and 12°C), using nine different diets with varying contents of phytosterols, cholesterol and phytosterol:cholesterol ratio. Cholesterol retention values were clearly dependent on dietary cholesterol, and showed that fish fed cholesterol levels <1000 mg/kg feed produced considerable quantities of cholesterol de novo...
February 5, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29385791/the-influence-of-patients-nutritional-status-on-the-prevalence-course-and-treatment-outcomes-of-lower-limb-ischemia-an-overview-of-current-evidence
#20
Marta Spychalska-Zwolińska, Tomasz Zwoliński, Marzena Anaszewicz, Jacek Budzyński
INTRODUCTION: The association of lower limb ischemia (LLI) with disturbances in nutritional status, in respect to over- or undernutrition, is still uncertain. The aim of this study was to present the current state of knowledge on this issue. EVIDENCE ACQUISITION: Systematic review of papers published between 2006 and 2018. EVIDENCE SYNTHESIS: The literature shows inconclusive evidence regarding the impact of nutritional status on the risk, course, prognosis and outcomes of conservative and invasive treatment of LLI...
January 31, 2018: International Angiology: a Journal of the International Union of Angiology
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