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sleep apnea & female

Gulgun Cetintas Afsar, Ozlem Oruc, Sema Sarac, Özgür Bilgin Topçuoğlu, Cuneyt Salturk, Fatma Merve Tepetam, Ismet Bulut
BACKGROUND: Obstructive sleep apnea (OSA) is the most common sleep disorder affecting 2-4 % of the adult population. In addition to several potential mechanisms, inflammation is one of the suggested etiological factors in OSA. Fractalkine/CX3CL1 which is detected in activated or stressed endothelium, smooth muscle cells, skeletal muscle cells, macrophages, neurons, and hepatocytes is an inflammatory marker and attracts attention of sleep specialists in OSA pathogenesis. In this study, we had two goals...
October 17, 2016: Sleep & Breathing, Schlaf & Atmung
Graciela E Silva, James L Goodwin, Kimberly D Vana, Stuart F Quan
INTRODUCTION: The impact of sleep on quality of life (QoL) has been well documented; however, there is a great need for reliable QoL measures for persons with obstructive sleep apnea (OSA). We compared the QoL scores between the 36-Item Short Form of the Medical Outcomes Survey (SF-36), Calgary Sleep Apnea Quality of Life Index (SAQLI), and Functional Outcomes Sleep Questionnaire (FOSQ) in persons with OSA. METHODS: A total of 884 participants from the Sleep Heart Health Study second examination, who completed the SF-36, FOSQ, and SAQLI, and in-home polysomnograms, were included...
2016: Southwest Journal of Pulmonary & Critical Care
Shengli Ma, Xue Rui, Peiyi Qi, Gangqiong Liu, Jing Yang
BACKGROUND: Poor sleep is common in patients with multiple sclerosis (MS). This study assessed the prevalence of poor sleep and investigated the potential impact factors that influence sleep quality of patients with MS. METHODS: A cross-sectional self-report survey of 231 patients with MS and 265 sex- and age-matched controls was conducted. Good sleepers and poor sleepers were separated by their global score on the Pittsburgh Sleep Quality Index (PSQI). Sociodemographic parameters, such as age, gender, and marital status, and clinical-demographic parameters, such as excessive daytime sleepiness (measured by the Epworth Sleepiness Scale), snoring, insomnia, obstructive sleep apnea, drugs, pain, depression, fatigue, and quality of life, were registered...
October 11, 2016: Sleep & Breathing, Schlaf & Atmung
Hadi A R Khafaji, Kadhim Sulaiman, Rajvir Singh, Khalid F Alhabib, Nidal Asaad, Alawi Alsheikh-Ali, Mohammed Al-Jarallah, Bassam Bulbanat, Wael Almahmeed, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam Al Faleh, Abdelfatah Elasfar, Prashanth Panduranga, Jassim Al Suwaidi
BACKGROUND: The purpose of this study was to report the prevalence, clinical characteristics, contributing factors, management and outcome of patients with chronic obstructive pulmonary disease (COPD) among patients hospitalized with heart failure (HF). METHODS: Data were derived from Gulf Care (Gulf acute heart failure registry), a prospective multicenter study of 5005 consecutive patients hospitalized with acute heart failure during February to November 2012 in seven Middle Eastern countries...
December 2015: Acute Cardiac Care
Brian N Palen, Lucas M Donovan, Elizabeth C Parsons
A 56-year-old obese female with depression was referred for evaluation of snoring, witnessed apneas, and daytime fatigue. Prescribed medications included bupropion and sertraline. Split-night polysomnography was performed. The diagnostic portion revealed total sleep time of 112 minutes, the absence of REM sleep, and an apnea-hypopnea index (AHI) of 54 events per hour. Continuous positive airway pressure (PAP) titration was then initiated starting at 5 cm H2O. At a pressure of approximately 12 cm H2O, the patient entered a long uninterrupted period of REM sleep lasting 140 minutes (Fig...
September 29, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Jong In Jeong, Seonhye Gu, Juhee Cho, Sang Duk Hong, Su Jin Kim, Hun-Jong Dhong, Seung-Kyu Chung, Hyo Yeol Kim
OBJECTIVE: Considering the mechanisms by which obesity affects obstructive sleep apnea syndrome (OSAS) and the differences of fat distribution depending on gender, associations between anthropometric parameters, and OSAS may differ depending on gender or sleep position. We analyzed the impact of gender and sleep position on the relationship between fat distribution and development of OSAS. METHODS: One thousand thirty-two consecutive subjects were analyzed. Recorded anthropometric measurements and overnight polysomnographic data of the subjects were reviewed retrospectively...
October 5, 2016: Sleep & Breathing, Schlaf & Atmung
Eduardo Anitua, Juan Saracho, Gabriela Zamora Almeida, Joquin Duran-Cantolla, Mohammad Alkhraisat
Sleep bruxism and higher clench index have been associated with obstructive sleep apnea (OSA). However, there is no study that reports on the prosthetic complications in patients with OSA. Patients' records, who had performed a sleep study to diagnose OSA, were examined for the occurrence of prosthetic complications in implant-borne reconstructions. The primary outcome was the frequency of prosthetic complications. The secondary outcomes were anthropometric data, the type of the complication, type of the prosthesis, type of retention, number of supporting implants, number of prosthetic units, and the presence of obstructive sleep apnea...
October 4, 2016: Journal of Oral Implantology
Keri S Taylor, Hisayoshi Murai, Philip J Millar, Nobuhiko Haruki, Derek S Kimmerly, Beverley L Morris, George Tomlinson, T Douglas Bradley, John S Floras
Obstructive apnea during sleep elevates the set point for efferent sympathetic outflow during wakefulness. Such resetting is attributed to hypoxia-induced upregulation of peripheral chemoreceptor and brain stem sympathetic function. Whether recurrent arousal from sleep also influences daytime muscle sympathetic nerve activity is unknown. We therefore tested, in a cohort of 48 primarily nonsleepy, middle-aged, male (30) and female (18) volunteers (age: 59±1 years, mean±SE), the hypothesis that the frequency of arousals from sleep (arousal index) would relate to daytime muscle sympathetic burst incidence, independently of the frequency of apnea or its severity...
October 3, 2016: Hypertension
Yeonsu Song, Donna L Washington, Elizabeth M Yano, Susan M McCurry, Constance H Fung, Joseph M Dzierzewski, Juan Carlos Rodriguez, Stella Jouldjian, Michael N Mitchell, Cathy A Alessi, Jennifer L Martin
OBJECTIVE/BACKGROUND: To identify caregiving-related sleep problems and their relationship to mental health and daytime function in female Veterans. PARTICIPANTS: Female Veterans (N = 1,477) from cross-sectional, nationwide, postal survey data. METHODS: The survey respondent characteristics included demographics, comorbidity, physical activity, health, use of sleep medications, and history of sleep apnea. They self-identified caregiving- related sleep problems (i...
October 3, 2016: Behavioral Sleep Medicine
K I Konovalova, E M Elfimova, E A Butorova, A V Aksenova, P V Galitsin, O S Bulkina, A Yu Litvin, I E Chazova
The paper describes a clinical case of a female patient with severe obstructive sleep apnea syndrome in the presence of congenital hemangioma of the face, soft palate, and tongue concurrent with paroxysmal atrial fibrillation and atrial flutter, paroxysmal supraventricular tachycardia, and sinoatrial block (maximally up to 3.9 sec). Continuous positive airway pressure therapy could reduce the number of paroxysms of atrial fibrillation and atrial flutter, supraventricular tachycardia and eliminate sinoatrial block...
2016: Terapevticheskiĭ Arkhiv
Girardin Jean-Louis, Valerie Newsome, Natasha J Williams, Ferdinand Zizi, Joseph Ravenell, Gbenga Ogedegbe
STUDY OBJECTIVES: To assess effectiveness of a culturally and linguistically tailored, telephone-delivered intervention to increase adherence to physician-recommended evaluation and treatment of obstructive sleep apnea (OSA) among blacks. METHODS: In a two-arm randomized controlled trial, we evaluated effectiveness of the tailored intervention among blacks with metabolic syndrome, relative to those in an attention-control arm (n = 380; mean age = 58 + 13; female = 71%)...
September 9, 2016: Sleep
Rick F Nelson, Joseph P Roche, Bruce J Gantz, Marlan R Hansen
OBJECTIVE: To determine the efficacy and morbidity of repairing spontaneous cerebrospinal fluid (CSF) leaks with the middle cranial fossa (MCF) approach without the use of a lumbar drain (LD), as perioperative use of LD remains controversial. STUDY DESIGN: Retrospective review from 2003 to 2015. SETTING: University of Iowa Hospitals and Clinics and Indiana University Health Center. PATIENTS: Those with a confirmed lateral skull base spontaneous CSF leaks and/or encephaloceles...
September 14, 2016: Otology & Neurotology
Dennis Liu, Hannah Myles, Debra L Foley, Gerald F Watts, Vera A Morgan, David Castle, Anna Waterreus, Andrew Mackinnon, Cherrie Ann Galletly
BACKGROUND: Obstructive sleep apnea (OSA) in the general community is associated with obesity, smoking, alcohol, and sedative medication use and contributes to depressed mood, daytime sedation, and sudden cardiovascular deaths. Poor cardiovascular health, impaired social functioning, and negative and cognitive symptoms are also among the common clinical features of psychotic disorders. People with psychosis have higher rates of sleep disturbance; however, OSA has not been extensively investigated in this population...
2016: Frontiers in Psychiatry
Stacey Ishman, Christine Heubi, Todd Jenkins, Marc Michalsky, Narong Simakajornboon, Thomas Inge
OBJECTIVE: Obstructive sleep apnea (OSA) is reported in 70% of adolescents who present for bariatric surgery. The Pediatric Sleep Questionnaire (PSQ) was developed to identify children at risk for OSA but is not validated in adolescents with obesity. The aims of this study were: (1) to assess validity of the PSQ to detect OSA and (2) to determine the correlation between anthropometric and polysomnography measurements. METHODS: A cross-sectional assessment of Teen-Longitudinal Assessment of Bariatric Surgery participants at high risk for OSA was performed...
September 15, 2016: Obesity
Itthiphat Arunsurat, Swita Luengyosluechakul, Krittin Prateephoungrat, Pittayapoom Siripaupradist, Sukanya Khemtong, Kunranan Jamcharoensup, Narin Thanapatkaiporn, Panita Limpawattana, Supawan Laohasiriwong, Somdej Pinitsoontorn, Sirintip Boonjaraspinyo, Kittisak Sawanyawisuth
Obstructive Sleep Apnea (OSA) is a common disease associated with major cardiovascular diseases. Male subjects are more at higher risk for OSA than female subjects. The Berlin questionnaire is a beneficial screening tool for OSA and has 14 items. The Berlin questionnaire may need some adjustment for Thai or Asian populations. We aimed to find items that should be asked in the Berlin questionnaire to identify high risk for obstructive sleep apnea among Thai male healthcare workers. This study was performed in Thai male healthcare workers over the age of 35 and currently working at the Faculty of Medicine, Khon Kaen University...
September 2016: Journal of UOEH
Md Basunia, Samir A Fahmy, Frances Schmidt, Chidozie Agu, Bikash Bhattarai, Vikram Oke, Danilo Enriquez, Joseph Quist
BACKGROUND: Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) present with a variety of sleep-related symptoms. In polysomnography, sleep architecture is almost always abnormal, but it is not known which of the sleep-stage abnormalities are related to symptoms. Finding key sleep-stage abnormality that cause symptoms may be of therapeutic importance to alleviate symptoms. So far the mainstay of treatment is continuous positive airway pressure (CPAP)/bi-level positive airway pressure (BIPAP) therapy, but many patients are non-compliant to it...
2016: Journal of Community Hospital Internal Medicine Perspectives
Irtaza Khan, Arjun B Chatterjee, Christina R Bellinger, Edward Haponik
BACKGROUND: Bronchoscopy is a safe and minimally invasive diagnostic tool, but no studies have reported prospectively on sedation and outcomes in patients with objectively defined obesity. OBJECTIVES: The purpose of the study is to determine if obese patients require more sedation or had more procedural complications during bronchoscopy under moderate sedation than non-obese patients. METHODS: We evaluated complications and sedation requirements in non-obese versus obese patients, defined by multiple criteria including body mass index (BMI), neck circumference, abdominal height, and Mallampati scores...
2016: Respiration; International Review of Thoracic Diseases
Selami Ekin, Mahfuz Turan, Ahmet Arısoy, Hulya Gunbatar, Aysel Sunnetcioglu, Selvi Asker, Hanifi Yıldız
BACKGROUND Obstructive sleep apnea (OSA) is a common disorder with an estimated prevalence in the general population of 2-5%. Its main clinical features are loud snoring and breathing stoppage during sleep. Ischemia could be a consequence of noise-induced hearing loss because cochlear oxygen tension is reduced during and after noise exposure. In this study, we evaluated auditory function in patients affected by OSA and simple snoring. MATERIAL AND METHODS A total of 66 participants (male to female ratio: 40:26) were included in the study, of which 21 were in the control group, 18 were in the simple snoring group, and 27 were in the OSA patient group...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Tomor Harnod, Yu-Chiao Wang, Chia-Hung Kao
OBJECTIVE: This nationwide population-based cohort study evaluated the effects of nonapnea sleep disorders (NSDs) on the development of epilepsy. METHODS: We identified 63,865 patients aged ≥20years, diagnosed with NSDs (ICD-9-CM: 307.4 or 780.5), and without coding for apnea-related sleep disorders (ICD-9-CM: 780.51, 780.53, or 780.57) during 2000-2003 as the NSD cohort. In addition, we enrolled a comparison cohort of 127,728 patients. We calculated the adjusted hazard ratio (aHR) for developing epilepsy (ICD-9-CM: 345) after adjustment for age, sex, comorbidities, and drug use...
October 2016: Preventive Medicine
Pilar Rovira Martí, Rosendo Ullot Font
PURPOSE: Pycnodysostosis is a rare autosomal recessive genetic disorder usually diagnosed at an early age. The few previously published case series have generally focused on maxillofacial manifestations and genetic considerations. The purpose of this study was to evaluate the clinical characteristics and differential diagnosis of pycnodysostosis focusing on its orthopaedic manifestations, which have been poorly described in the literature. METHODS: We evaluated clinical and radiographic characteristics of five patients with pycnodysostosis...
August 25, 2016: International Orthopaedics
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