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sleep disordered breathing & female

Jorge Soliz, Rose Tam, Richard Kinkead
Perinatal exposure to adverse experiences disrupts brain development, including the brainstem network that regulates breathing. At adulthood, rats previously subjected to stress (in the form of neonatal maternal separation; NMS) display features reported in patients suffering from sleep disordered breathing, including an increased hypoxic ventilatory response and hypertension. This effect is also sex-specific (males only). Based on these observations, we hypothesized that NMS augments the carotid body's O2-chemosensitivity...
2016: Frontiers in Physiology
Dennis Liu, Hannah Myles, Debra L Foley, Gerald F Watts, Vera A Morgan, David Castle, Anna Waterreus, Andrew Mackinnon, Cherrie Ann Galletly
BACKGROUND: Obstructive sleep apnea (OSA) in the general community is associated with obesity, smoking, alcohol, and sedative medication use and contributes to depressed mood, daytime sedation, and sudden cardiovascular deaths. Poor cardiovascular health, impaired social functioning, and negative and cognitive symptoms are also among the common clinical features of psychotic disorders. People with psychosis have higher rates of sleep disturbance; however, OSA has not been extensively investigated in this population...
2016: Frontiers in Psychiatry
Selami Ekin, Mahfuz Turan, Ahmet Arısoy, Hulya Gunbatar, Aysel Sunnetcioglu, Selvi Asker, Hanifi Yıldız
BACKGROUND Obstructive sleep apnea (OSA) is a common disorder with an estimated prevalence in the general population of 2-5%. Its main clinical features are loud snoring and breathing stoppage during sleep. Ischemia could be a consequence of noise-induced hearing loss because cochlear oxygen tension is reduced during and after noise exposure. In this study, we evaluated auditory function in patients affected by OSA and simple snoring. MATERIAL AND METHODS A total of 66 participants (male to female ratio: 40:26) were included in the study, of which 21 were in the control group, 18 were in the simple snoring group, and 27 were in the OSA patient group...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Sandra Larcher, Anne-Sophie Gauchez, Sandrine Lablanche, Jean-Louis Pépin, Pierre-Yves Benhamou, Anne-Laure Borel
BACKGROUND: Sleep behavior is changing toward shorter sleep duration and a later chronotype. It results in a sleep debt that is acquitted on work-free days, inducing a small but recurrent sleep misalignment each week, referred to as "social jetlag". These sleep habits could affect health through misalignment with circadian rhythms. OBJECTIVES: The primary objective is to address the impact of sleep behavior on glycemic control, assessed by HbA1c, in patients with type 1 diabetes, independently of other lifestyle or sleep-related factors...
November 2016: European Journal of Endocrinology
Alyssa Cairns, Greg Poulos, Richard Bogan
STUDY OBJECTIVES: To evaluate sex differences in predictors of obstructive sleep apnea (OSA) as per outcomes from home sleep apnea testing. DESIGN: This was a retrospective analysis of a large repository of anonymous test results and pretest risk factors for OSA. SETTING AND PATIENTS: A total of 272,705 patients were referred for home sleep apnea testing from a variety of clinical practices for suspected sleep disordered breathing across North America from 2009 to 2013...
2016: Nature and Science of Sleep
Sahajal Dhooria, Inderpaul Singh Sehgal, Anshu Kumar Agrawal, Ritesh Agarwal, Ashutosh Nath Aggarwal, Digambar Behera
BACKGROUND AND AIMS: This study aims to evaluate the sleep quality, architecture, sleep-related quality of life, and sleep-disordered breathing (SDB) in acute respiratory distress syndrome (ARDS) survivors early after discharge. MATERIALS AND METHODS: In this prospective, observational study, consecutive patients with ARDS discharged from the Intensive Care Unit (ICU) underwent evaluation with Epworth sleepiness scale (ESS), Pittsburgh Sleep Quality Index (PSQI), Functional Outcomes of Sleep Questionnaire (FOSQ), and overnight polysomnography...
June 2016: Indian Journal of Critical Care Medicine
Joanna Michalska, Jurek Olszewski, Marzena Mielczarek
INTRODUCTION: The aim of this work was to evaluate the correlation between Apnea/Hypopnea Index (AHI) and selected parameters of morphological and clinical character in the patients with a unilateral or bilateral impairment of nasal patency. MATERIAL AND METHODS: The study covered 60 adults, including 37 male and 23 female subjects, 19-69 years of age. In the Department, these subjects were divided into 3 groups: I - 20 patients with unilateral impairment of nasal patency, II - 20 patients with bilateral impairment of nasal patency, III - controls with normal nasal patency...
April 30, 2016: Otolaryngologia Polska. the Polish Otolaryngology
Shaloo Gupta, Zhixiao Wang
AIMS: This study examined the prevalence of sleep disorders (SD) and self-reported sleep symptoms and risk factors among adult patients diagnosed with T2DM. METHODS: Data were obtained from the 2012 US National Health and Wellness Survey, an annual Internet-based survey. A total of 7239 participants reported a diagnosis of T2DM. Patients also provided information on diagnosis of SD (e.g., insomnia, sleep breathing disorder, other sleep conditions, etc.) and regularly experienced sleep symptoms (e...
June 8, 2016: Diabetes & Metabolic Syndrome
Don S Urquhart, Olaniyi O Kehinde, Ailsa E Mclellan
AIM: To estimate symptoms of obstructive sleep apnoea (OSA) and excessive daytime sleepiness (EDS) in children with epilepsy (CWE) compared with those in a typically developing comparison group. CWE are known to have poor sleep, with increased rates of OSA suggested. METHOD: The Sleep-Related Breathing Disorder scale of the Pediatric Sleep Questionnaire (PSQ-SRBD) was used to estimate OSA symptoms, with scores ≤0.33 known to be highly sensitive and specific for OSA...
October 2016: Developmental Medicine and Child Neurology
Silvia Miano, Maria Esposito, Giuseppe Foderaro, Gian Paolo Ramelli, Valdo Pezzoli, Mauro Manconi
BACKGROUND AND METHODS: We present the preliminary results of a prospective case-control sleep study in children with a diagnosis of attention-deficit hyperactivity disorder (ADHD). A deep sleep assessment including sleep questionnaires, sleep habits, a video-polysomnographic recording with full high-density electroencephalography (EEG) and cardiorespiratory polygraphy, multiple sleep latency test, and 1-week actigraphic recording were performed to verify whether children with ADHD may be classified into one of the following five phenotypes: (1) hypoarousal state, resembling narcolepsy, which may be considered a "primary" form of ADHD; (2) delayed sleep onset insomnia; (3) sleep-disordered breathing; (4) restless legs syndrome and/or periodic limb movements; and (5) sleep epilepsy and/or EEG interictal epileptiform discharges...
June 3, 2016: CNS Neuroscience & Therapeutics
Hela Marmouch, Sondes Arfa, Sameh Graja, Tensim Slim, Ines Khochtali
A 52-year-old female with a history of poorly controlled resistant hypertension was admitted to our hospital with severe hypertension. She had a history of fatigue and intermittent episodes of palpitations. Laboratory evaluation was significant for elevated 24-h urinary catecholamine levels (3,5 times the upper normal levels). This case was presenting with a clinical and biochemical picture indistinguishable from that of pheochromocytoma. However, neither computed tomography nor meta-iodo-benzyl-guanidine scintigraphy detected any catecholamine-producing tumor in or outside the adrenal glands...
2016: Pan African Medical Journal
Umpei Yamamoto, Mari Nishizaka, Chikara Yoshimura, Nobutoshi Kawagoe, Atsumi Hayashi, Toshiaki Kadokami, Shin-Ichi Ando
OBJECTIVE: We assessed the prevalence of sleep disordered breathing (SDB) and characteristics among patients who visited a urology clinic complaining of nocturia (URO group) and those who visited a sleep apnea (SA) clinic complaining of excessive daytime sleepiness (EDS) (SA group). Additionally, we evaluated the effects of continuous positive airway pressure (CPAP) therapy in the URO group patients with nocturia and SDB resistant to conventional therapy for nocturia. METHODS: Questionnaires were used to assess EDS, nocturia and lower urinary tract symptoms in 34 URO group patients and 49 age-matched SA group patients...
2016: Internal Medicine
Anna Maria Zicari, Francesca Occasi, Federica Di Mauro, Valeria Lollobrigida, Marco Di Fraia, Vincenzo Savastano, Lorenzo Loffredo, Francesco Nicita, Alberto Spalice, Marzia Duse
INTRODUCTION: Studies on Mean Platelet Volume (MPV) in children with Sleep Disordered Breathing (SDB) report conflicting results and the hypothesis of an intermittent hypoxemia leading to a systemic inflammation is reaching consensus. Vitamin D exerts anti-inflammatory properties and its deficiency has been supposed to play a role in sleep disorders. Emerging interest is rising about Primary Snoring (PS) since it is reasonable that also undetectable alteration of hypoxia might predispose to an increased production of inflammatory mediators...
2016: PloS One
Ajoy Mathew Varghese, P Naina, Alan T Cheng, Syed Kamran Asif, Mary Kurien
OBJECTIVES: To propose a novel endoscopic adenoid grading system using a rigid nasal endoscope and to study its correlation with the clinical diagnosis. METHODOLOGY: Prerecorded video clips of rigid nasal endoscopy taken during endoscopic adenoidectomy were retrieved. Otolaryngology consultants blinded to the clinical diagnosis of the child were presented these videos and asked to grade the adenoid hypertrophy as per the proposed endoscopic ACE (Airway/Choana/Eustachian tube) grading system...
April 2016: International Journal of Pediatric Otorhinolaryngology
Ricardo S Osorio, Emma L Ducca, Margaret E Wohlleber, Emily B Tanzi, Tyler Gumb, Akosua Twumasi, Samuel Tweardy, Clifton Lewis, Esther Fischer, Viachaslau Koushyk, Maria Cuartero-Toledo, Mohammed O Sheikh, Elizabeth Pirraglia, Henrik Zetterberg, Kaj Blennow, Shou-En Lu, Lisa Mosconi, Lidia Glodzik, Sonja Schuetz, Andrew W Varga, Indu Ayappa, David M Rapoport, Mony J de Leon
STUDY OBJECTIVES: To evaluate the role of orexin-A with respect to cerebrospinal fluid (CSF) Alzheimer disease (AD) biomarkers, and explore its relationship to cognition and sleep characteristics in a group of cognitively normal elderly individuals. METHODS: Subjects were recruited from multiple community sources for National Institutes of Health supported studies on normal aging, sleep and CSF biomarkers. Sixty-three participants underwent home monitoring for sleep-disordered breathing, clinical, sleep and cognitive evaluations, as well as a lumbar puncture to obtain CSF...
2016: Sleep
Maria-Eleni Roumelioti, Christos Argyropoulos, Vernon Shane Pankratz, Manisha Jhamb, Filitsa H Bender, Daniel J Buysse, Patrick Strollo, Mark L Unruh
BACKGROUND: Automated peritoneal dialysis (APD) is one of the fastest growing dialysis modalities. It is unknown whether sleep and mood are disturbed while performing repeated overnight exchanges. OBJECTIVES: In this report, we aim to describe and compare the prevalence of sleep-disordered breathing (SDB), periodic limb movements (PLMS), poor sleep quality (SQ), and depression among APD patients compared with stages 3b-5 (estimated glomerular filtration rate ≤44 ml/min/1...
2016: Canadian Journal of Kidney Health and Disease
Shumei Xu, Ying Xue
Pediatric or childhood obesity is the most prevalent nutritional disorder among children and adolescents worldwide. Approximately 43 million individuals are obese, 21-24% children and adolescents are overweight, and 16-18% of individuals have abdominal obesity. The prevalence of obesity is highest among specific ethnic groups. Obesity increases the risk of heart diseases in children and adults. Childhood obesity predisposes the individual to insulin resistance and type 2 diabetes, hypertension, hyperlipidemia, liver and kidney diseases and causes reproductive dysfunction in adults...
January 2016: Experimental and Therapeutic Medicine
Jiachao Qi, Qichang Lin, Xin Lin, Xiao Chen
OBJECTIVE: To evaluate the relationship of visceral adiposity index (VAI) with serum aminotransferase levels and incidence of nonalcoholic fatty liver disease (NAFLD) in patients with sleep apnea (SA). METHODS: Between January 2011 and December 2014, participants who were referred from Fujian Provincial Sleep-disordered Breathing (SDB) Clinic Center with repeated snoring or a clinical suspicion of SDB were recruited. All individuals underwent polysomnography (PSG) testing and an abdominal ultrasonography scan during this period...
November 10, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Catherine L Davis, Martha S Tingen, Jenny Jia, Forrest Sherman, Celestine F Williams, Kruti Bhavsar, Nancy Wood, Jessica Kobleur, Jennifer L Waller
BACKGROUND: Passive smoke exposure (PSE) may be a risk factor for childhood overweight and obesity and is associated with worse neurocognitive development, cognition, and sleep in children. The purpose of the study is to examine the effects of PSE on adiposity, cognition, and sleep in overweight and obese children using an objective measure of PSE. METHODS: Overweight or obese children (n = 222) aged 7-11 (9.4 ± 1.1 years; 58% black; 58% female; 85% obese) were recruited from schools near Augusta, Georgia, over the course of the school year from 2003-2006 for a clinical trial, with data analyzed in 2009-2010...
April 2016: Childhood Obesity
Tshering Amdo, Nadia Hasaneen, Morris S Gold, Avram R Gold
OBJECTIVES: We tested the hypothesis that the prevalence of somatic syndromes, anxiety, and insomnia among sleep disordered breathing (SDB) patients is correlated with their levels of somatic arousal, the symptoms of increased sympathetic nervous system tone under conditions of stress. METHODS: We administered the Body Sensation Questionnaire (BSQ; a 17-item questionnaire with increasing levels of somatic arousal scored 17-85) to 152 consecutive upper airway resistance syndrome (UARS) patients and 150 consecutive obstructive sleep apnea/hypopnea (OSA/H) patients...
May 2016: Sleep & Breathing, Schlaf & Atmung
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