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https://www.readbyqxmd.com/read/28229168/cd14-cd16-nonclassical-monocytes-are-associated-with-endothelial-dysfunction-in-patients-with-coronary-artery-disease
#1
Karol Urbanski, Dominik Ludew, Grzegorz Filip, Magdalena Filip, Agnieszka Sagan, Piotr Szczepaniak, Grzegorz Grudzien, Jerzy Sadowski, Barbara Jasiewicz-Honkisz, Tomasz Sliwa, Boguslaw Kapelak, Eilidh McGinnigle, Tomasz Mikolajczyk, Tomasz J Guzik
Endothelial dysfunction and inflammation are key mechanisms of vascular disease. We hypothesised that heterogeneity of monocyte subpopulations may be related to the development of vascular dysfunction in coronary artery disease (CAD). Therefore, we examined the relationships between monocyte subsets (CD14(++)CD16(-) "classical - Mon1", CD14(++)CD16(+) "intermediate - Mon2" and CD14(+)CD16(++) "nonclassical - Mon3"), endothelial function and risk factor profiles in 130 patients with CAD undergoing coronary artery bypass grafting...
February 23, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28219559/neovascularization-of-thymoma-from-left-internal-mammary-artery-bypass-graft
#2
Jordan Y Dubique, Harma Turbendian, Danny Chu
We present the case of a type AB thymoma in a 69-year-old man with previous coronary artery bypass grafting (CABG) in whom angiography revealed a left internal mammary artery graft supplying blood flow to a thymic neoplasm, which simultaneously occluded the graft. This required a redo sternotomy, lysis of pericardial adhesions, complete thymectomy, and redo one vessel off-pump CABG. This case seeks to sensitize physicians to the possibility of coronary adverse events in patients with a previous CABG in the setting of management of mediastinal neoplasms, and it presents the novel findings on cardiac imaging associated with this case...
March 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28201864/recurrent-contrast-induced-encephalopathy-following-coronary-angiography
#3
Roberto Spina, Neil Simon, Romesh Markus, David W M Muller, Krishna Kathir
Contrast-induced encephalopathy (CIE) is an acute and reversible neurological disturbance associated with the intra-arterial administration of iodinated contrast medium during cardiac catheterisation. It may manifest with encephalopathy, motor and sensory disturbances; vision disturbances, including cortical blindness, ophthalmoplegia, aphasia; and seizures. Disruption of the blood-brain barrier and direct neuronal toxicity are believed to be implicated in the pathophysiology of the syndrome. Symptoms appear soon after contrast administration and resolve completely within 24-48 h...
February 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28186272/bilateral-internal-mammary-artery-y-construct-with-multiple-sequential-grafting-improves-survival-compared-to-bilateral-internal-mammary-artery-with-additional-vein-grafts-10-year-experience-at-2-different-institutions%C3%A2
#4
David Glineur, Pierre-Yves Etienne, Cyrus E Kuschner, Richard E Shaw, Giovanni Ferrari, Nancy Rioux, Spiridon Papadatos, Mariano Brizzio, Bruce Mindich, Alex Zapolanski, Juan B Grau
No abstract text is available yet for this article.
February 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28182034/topical-vasodilator-response-in-skeletonized-internal-mammary-artery-is-there-really-a-difference
#5
Syed Raza Shah, Syed Arbab Shah, Muhammad Ahmed Jangda, Mohammad Danial Yaqub, Ayesha Altaf Jangda, Maham Khan, Muhammad Asim Khan, Brian Tomkins
AIM OF THE STUDY: Coronary artery bypass graft surgery is the gold standard for the treatment of multivessel and left main coronary artery disease. However, there is considerable debate that whether left internal mammary artery (IMA) should be taken as pedicled or skeletonized. This study was conducted to assess the difference in blood flow after the application of topical vasodilator in skeletonized and pedicled IMA. MATERIALS AND METHODS: In this study, each patient underwent either skeletonized (n = 25) or pedicled IMA harvesting (n = 25)...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28163839/interventional-treatment-of-the-left-subclavian-in-2-patients-with-coronary-steal-syndrome
#6
Julia Heid, Britta Vogel, Arnt Kristen, Wanda Kloos, Benedikt Kohler, Hugo A Katus, Grigorios Korosoglou
In patients with history of coronary artery disease angina pectoris is usually attributed to the progression of atherosclerotic lesions. However, in patients with previous coronary artery bypass graft operation (CABG) using internal mammary artery grafts, great vessel disease should also be considered. Herein we present two patients with history of CABG whose symptoms were suspicious for coronary ischemia. During cardiac catheterization reverse blood flow was observed from the left artery disease to the left internal mammary artery (LIMA) graft in both cases...
January 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28155726/on-the-relationship-between-competitive-flow-and-fft-analysis-of-the-flow-waves-in-the-left-internal-mammary-artery-graft-in-the-process-of-cabg
#7
Boyan Mao, Wenxin Wang, Zhou Zhao, Xi Zhao, Lanlan Li, Huixia Zhang, Youjun Liu
BACKGROUND: During coronary artery bypass grafting (CABG), the ratio of powers of the fundamental frequency and its first harmonic (F0/H1) in fast Fourier transformation (FFT) analysis of the graft's flow waves has been used in the field of evaluation of the patency in anastomosis. But there is no report about using the FFT method to evaluate the magnitude of competitive flow. This study is aiming at exploring the relationship between competitive flow and FFT analysis of the flow waves in left internal mammary artery (LIMA) graft, and finding a new method to evaluate the magnitude of competitive flow...
December 28, 2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28144710/selective-venous-vasodilator-properties-of-the-analgesic-metamizole-dipyrone-in-a-human-ex-vivo-model-implications-for-postoperative-pain-management
#8
Markus Hoenicka, Hagen Gorki, Karl Traeger, Andreas Liebold
Metamizole (dipyrone) is a first-line, non-opioid analgesic used for postoperative pain management. Clinical data and animal experiments indicate a possible vasodilator action of this drug. We investigated the effects of metamizole on human artery and vein tone in an ex vivo model to assess potential contributions to venous pooling. Excess segments of bypass grafts were harvested during coronary artery bypass grafting procedures. Tensions were measured in an organ bath for 120 min after adding metamizole to the preconstricted vessels...
January 31, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28139424/the-impact-of-active-breathing-control-on-internal-mammary-lymph-node-coverage-and-normal-tissue-exposure-in-breast-cancer-patients-planned-for-left-sided-postmastectomy-radiation-therapy
#9
Aisling Barry, Kathy Rock, Claudio Sole, Mohammad Rahman, Melania Pintilie, Grace Lee, Anthony Fyles, C Anne Koch
PURPOSE: The purpose of this study was to evaluate the impact of the active breathing control (ABC) technique on IMN coverage and organs at risk in patients planned for postmastectomy radiation therapy (PMRT), with the inclusion of the internal mammary lymph nodes (IMNs). The effect of body mass index (BMI) on recorded dosimetric parameters was examined in the same patient cohort. METHODS AND MATERIALS: Fifty left-sided postmastectomy patients with breast cancer who underwent free-breathing (FB) and ABC-Elekta CT simulation scans were selected at random from an institutional breast cancer database between 2008 and 2014...
December 7, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28138727/preoperative-localization-of-mediastinal-parathyroid-adenoma-with-intra-arterial-methylene-blue
#10
Rida Salman, Mikhael G Sebaaly, Mohammad Rachad Wehbe, Pierre Sfeir, Mohamad Khalife, Aghiad Al-Kutoubi
Ectopic parathyroid is found in 16% of patients with hyperparathyroidism. 2% of ectopic parathyroid adenomas are not accessible to standard cervical excision. In such cases, video-assisted thoracoscopic resection is the recommended definitive treatment. We present a case of mediastinal parathyroid adenoma localized preoperatively by injecting methylene blue within a branch of the internal mammary artery that is supplying the adenoma. Intra-arterial methylene blue injection facilitated visualization and resection of the adenoma...
January 30, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28131424/outcomes-of-trainees-performing-coronary-artery-bypass-grafting-does-resident-experience-matter
#11
Kenan W Yount, Leora T Yarboro, Adishesh K Narahari, Ravi K Ghanta, Curtis G Tribble, Irving L Kron, John A Kern, Gorav Ailawadi
BACKGROUND: Outcomes after coronary artery bypass graft surgery (CABG) are known to be dependent on attending surgeon volume, but the impact of resident experience is unknown. Our objective was to assess the influence of resident experience to understand the learning curve for CABG. METHODS: From 2008 to 2014, all isolated on-pump CABG (n = 1,668) during which a resident performed the entire operation (including sternotomy, mammary artery harvest, coronary anastomoses, and closure) were reviewed...
January 25, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28120895/genomic-structural-variations-for-cardiovascular-and-metabolic-comorbidity
#12
Maria S Nazarenko, Aleksei A Sleptcov, Igor N Lebedev, Nikolay A Skryabin, Anton V Markov, Maria V Golubenko, Iuliia A Koroleva, Anton N Kazancev, Olga L Barbarash, Valery P Puzyrev
The objective of this study was to identify genes targeted by both copy number and copy-neutral changes in the right coronary arteries in the area of advanced atherosclerotic plaques and intact internal mammary arteries derived from the same individuals with comorbid coronary artery disease and metabolic syndrome. The artery samples from 10 patients were screened for genomic imbalances using array comparative genomic hybridization. Ninety high-confidence, identical copy number variations (CNVs) were detected...
January 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28110487/the-use-of-bilateral-internal-mammary-artery-grafting-in-different-degrees-of-obesity
#13
Yasser Y Hegazy, Wael Hassanein, Jürgen Ennker, Noha Keshk, Stefan Bauer, Ralf Sodian
Background Obesity is a limiting factor for the use of bilateral internal mammary arteries (BIMAs). Therefore, we assessed the safety of their use in different degrees of obesity. Patients and Methods We studied two groups of patients with obesity using propensity matching. The first group received single internal mammary artery and saphenous vein grafts (SIMA group, 526 patients) and the second group received bilateral internal mammary arteries (BIMA group, 526 patients). Patients were classified further according to their body mass index (BMI) into overweight (BMI = 25-29...
January 22, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28109967/subclavian-artery-disease-diagnosis-and-therapy
#14
REVIEW
Tisa Saha, Syed Yaseen Naqvi, Omar Abine Ayah, Daniel McCormick, Sheldon Goldberg
The diagnosis of brachiocephalic disease is often overlooked. Symptoms include arm claudication and vertebrobasilar insufficiency. In patients who have had the use of the internal mammary artery for coronary bypass surgery, the development of symptoms of myocardial ischemia should alert the clinician to the possibility of subclavian artery stenosis. Also, in patients who have had axillofemoral bypass, lower-extremity claudication may occur. Recognition involves physical examination and accurate noninvasive testing...
January 19, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28106964/off-pump-anastomosis-of-the-left-internal-mammary-artery-to-the-left-anterior-descending-coronary-artery-through-a-left-inferior-j-hemisternotomy
#15
Ivy Modrau, Per Nielsen, Dorthe Nielsen
Since the 1990s, a large body of literature has been published regarding minimally invasive coronary artery bypass grafting. Varying techniques, complexity of the procedures and the necessity of patient selection have led to its inconsistent application. We describe the standardized technique of left internal mammary artery grafting to the left anterior descending coronary artery, off-pump through a left inferior J-hemisternotomy (JOPCAB). This approach is straightforward, safe, effective, and replicable in virtually all patients...
December 9, 2016: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/28106619/video-assisted-thoracic-surgery-in-patients-with-previous-sternotomy-and-cardiac-surgery
#16
Derek R Serna-Gallegos, Heather E Merry, Robert J McKenna
OBJECTIVE: Although video-assisted thoracic surgery (VATS) lobectomy has become a standard approach for early-stage 1 lung cancer, concerns exist regarding potential damage to the heart or bypass grafts when VATS is performed after cardiac surgery via median sternotomy. We could find only case reports regarding VATS lobectomy after sternotomy for cardiac surgery. Therefore, we reviewed our series of patients who underwent VATS anatomic resections after sternotomy for cardiac surgery. METHODS: Between 1996 and 2010, there were 87 patients who underwent 88 pulmonary resections after sternotomy for coronary artery bypass grafting (64), valve replacement or repair (12), coronary artery bypass graft and valve replacement (6), and transplant (5)...
January 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28106618/right-internal-mammary-artery-use-in-140-robotic-totally-endoscopic-coronary-bypass-cases-toward-multiarterial-grafting
#17
Husam H Balkhy, Sandeep Nathan, Susan E Arnsdorf, Dorothy J Krienbring
OBJECTIVE: Benefits of adding a second arterial graft in coronary bypass are well documented. In patients requiring mulitvessel grafting robotic totally endoscopic coronary bypass (TECAB) has allowed for routine harvesting and use of the right internal mammary artery (RIMA). We retrospectively reviewed the technical considerations and target choice in 140 cases of beating heart TECAB where a RIMA graft was used. METHODS: In 2008, we introduced beating heart TECAB with anastomotic connectors into our practice, first with single IMA and then with bilateral internal mammary artery...
January 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28063673/-coronary-artery-bypass-graft-surgery-with-bilateral-internal-mamary-artery-short-term-results
#18
Josías Caleb Ríos Ortega, Paul Castañeda Castillo, Luisa Talledo Paredes, Franz Soplopuco Palacios, Necemio Aranda Pretell, Yemmy Pérez Valverde, Julio Morón Castro, Andrés Reyes Torres
INTRODUCTION: Coronary artery bypass graft (CABG) surgery remains the gold standard in the treatment of multivessel coronary disease. Several studies have shown that CABG with bilateral internal mammary arteries (BIMA) has better results in long-term survival. METHODOLOGY: We conducted a retrospective investigation in CABG surgeries with BIMA, performed from January 2012 to December 2015 in the National Cardiovascular Institute, INCOR, EsSalud. The objectives were determine the mortality and major cardiovascular events at 30 days follow up...
January 4, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28062549/redo-procedures-for-degenerated-stentless-aortic-xenografts-and-the-role-of-valve-in-valve-transcatheter-techniques%C3%A2
#19
Herko Grubitzsch, Sebastian Zobel, Torsten Christ, Sebastian Holinski, Karl Stangl, Sascha Treskatsch, Volkmar Falk, Michael Laule
OBJECTIVES: This study evaluates reinterventions for degenerated stentless aortic xenografts. METHODS: Between 2010 and 2015, 52 consecutive patients (age 72.3 ± 9.7 years, EuroSCORE II 11.1 ± 8.9%) underwent reintervention for failed stentless aortic valves (60% porcine, 40% pericardial, 87% sub-coronary, 81% isolated/combined regurgitation). RESULTS: Based on age, EuroSCORE II, the presence of pulmonary hypertension, renal failure, a patent internal mammary artery graft and required concomitant procedures, the heart team assigned 25 patients to reoperation and 27 to valve-in-valve transcatheter aortic valve implantation (ViV-TAVI)...
January 6, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28062506/wnt-signaling-pathway-inhibitor-sclerostin-inhibits-angiotensin-ii-induced-aortic-aneurysm-and-atherosclerosis
#20
Smriti Murali Krishna, Sai-Wang Seto, Roby J Jose, Jiaze Li, Susan K Morton, Erik Biros, Yutang Wang, Vianne Nsengiyumva, Jan H N Lindeman, Gabriela G Loots, Catherine M Rush, Jeffrey M Craig, Jonathan Golledge
OBJECTIVE: Sclerostin (SOST) has been identified as an important regulator of bone formation; however, it has not been previously implicated in arterial disease. The aim of this study was to assess the role of SOST in aortic aneurysm (AA) and atherosclerosis using human samples, a mouse model, and in vitro investigations. APPROACH AND RESULTS: SOST protein was downregulated in human and mouse AA samples compared with controls. Transgenic introduction of human SOST in apolipoprotein E-deficient (ApoE(-/-)) mice (SOST(Tg)...
December 22, 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
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