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https://www.readbyqxmd.com/read/29035780/long-non-coding-rnas-in-the-atherosclerotic-plaque
#1
Serdal Arslan, Öcal Berkan, Torkia Lalem, Nil Özbilüm, Sabahattin Göksel, Özge Korkmaz, Nilgün Çetin, Yvan Devaux
BACKGROUND AND AIMS: Genetic and environmental factors are important components of the development of atherosclerosis. Long non-coding RNA (lncRNAs) have emerged as regulators of multiple pathophysiological pathways in the cardiovascular system. Here, we investigated potential associations between lncRNAs and atherosclerosis. METHODS: Tissue samples from atherosclerotic coronary artery plaques and non-atherosclerotic internal mammary artery were obtained from 20 patients during coronary artery bypass surgery...
October 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29029008/complete-arterial-revascularization-using-bilateral-internal-mammary-artery-in-t-graft-technique-for-multivessel-coronary-artery-disease-in-on-or-off-pump-approach-does-gender-lose-its-historical-impact-on-clinical-outcome
#2
Friedrich-Christian Rieß, Christian-Alexander Behrendt, Wagma Amin, Stefan Heller, Lorenz Hansen, Stephan Winkel, Jan Stripling, Henrik Christian Rieß
OBJECTIVES: Higher rates of mortality and morbidity have been reported in women undergoing coronary artery bypass grafting (CABG) compared with men. Different revascularization techniques (on-pump and off-pump) might influence this outcome. METHODS: We retrospectively analysed 3445 consecutively recruited patients (all comers) undergoing complete arterial CABG (CACABG) at a single centre between January 2000 and December 2012. CACABG was performed in all patients using bilateral skeletonized internal mammary artery in T-graft technique, either on-pump (n = 2216) or off-pump (n = 1229)...
September 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29023352/novel-sternal-protection-device-for-cardiac-surgery-via-median-sternotomy-incision
#3
Silvana F Marasco, David C McGiffin, Adam D Zimmet, Pablo C Solis, Judy M Bingham, Randall A Moshinsky
OBJECTIVE: Sternal bleeding during cardiac surgery is currently controlled using bone wax or other chemical substances that may result in adverse effects and affect wound healing and recovery. The purpose of this study was to identify a safe, cost-effective, and easy-to-use technique to reduce sternal bleeding and sternal trauma during cardiac surgery. METHODS: After sternotomy, a sternal protection device was placed over each hemisternal section before insertion of the retractor and remained in situ until the end of surgery...
October 10, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29022414/iatrogenic-breast-infarct-following-coronary-artery-bypass-graft-surgery-with-harvesting-of-left-internal-mammary-artery
#4
Jacob Sweeney, Matthew Skovgard, Syed Hoda
No abstract text is available yet for this article.
October 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29021615/a-new-pedicled-internal-mammary-osteomyocutaneous-chimeric-flap-pimoc-for-salvage-head-and-neck-reconstruction-anatomic-study-and-clinical-application
#5
Guilherme C Barreiro, Chelsea C Snider, Flavio H F Galvão, Rachel R Baptista, Kiril E Kasai, Daniel M Dos Anjos, Marcus C Ferreira
Well-vascularized composite tissue offers improved outcomes for complex head and neck reconstruction. Patients with vessel-depleted necks and failed reconstructions require alternative reconstructive options. We describe a pedicled internal mammary artery osteomyocutaneous chimeric flap (PIMOC) for salvage head and neck reconstruction. Bilateral dissections of 35 fresh cadavers were performed to study individual tissue components and vascular pedicles to develop the PIMOC technique. The flap was then utilized in a series of patients with vessel-depleted neck anatomy...
October 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28990495/internal-mammary-artery-to-pulmonary-vasculature-fistula-systematic-review-of-case-reports
#6
Ali Abdul Jabbar, Amish Patel, Nathan Marzlin, Sayf Altabaqchali, Mohanad Hasan, Muhanad Al-Zubaidi, Ajay Agarwal
The formation of a fistula between the internal mammary artery and the pulmonary vasculature (IMA-to-PV) is a rare anomaly. The etiology can be congenital; however, most recent cases have been associated with coronary artery bypass grafting, trauma, inflammatory conditions, chronic infections, or neoplasia. The knowledge base on the formation of these fistulas is derived primarily from case reports. To our knowledge, no systematic reviews or guidelines are available that provide information on how to manage these cases, and the treatment of an IMA-to-PV fistula is controversial...
October 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28988450/feasibility-of-coronary-angiography-and-percutaneous-coronary-intervention-after-transcatheter-aortic-valve-replacement-using-a-medtronic%C3%A2-self-expandable-bioprosthetic-valve
#7
Wah Wah Htun, Cindy Grines, Theodore Schreiber
BACKGROUND AND OBJECTIVE: With aging, the progression of atherosclerosis in the coronary arteries is expected. The Medtronic™ self-expandable aortic bioprosthetic valve is deployed in the supra-annular position, and it has been challenging to selectively engage coronary arteries post-transcatheter aortic valve replacement (TAVR) even though there are diamond-shaped spaces in the mesh frame within the valve. Given the scarcity of data, we analyzed angiographic and clinical data from all patients requiring coronary angiography (CA) or intervention post-TAVR...
October 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28983446/flash-ostial-balloon-in-right-internal-mammary-artery-percutaneous-coronary-intervention-a-novel-approach
#8
Rupak Desai, Gautam Kumar
Despite the widespread use of coronary stents and effective anticoagulation regimens, the treatment of ostial lesions is limited by high restenosis rates. Ostial stenosis is a technically difficult condition to treat but this novel technique shows the ability to enable the optimal coverage of the ostium with excellent stent flaring using a Flash ostial balloon (Cardinal Health Inc., Dublin, OH).
August 2, 2017: Curēus
https://www.readbyqxmd.com/read/28972063/current-practice-of-state-of-the-art-surgical-coronary-revascularization
#9
REVIEW
Stuart J Head, Milan Milojevic, David P Taggart, John D Puskas
Coronary artery bypass grafting remains one of the most commonly performed major surgeries, with well-established symptomatic and prognostic benefits in patients with multivessel and left main coronary artery disease. This review summarizes current indications, contemporary practice, and outcomes of coronary artery bypass grafting. Despite an increasingly higher-risk profile of patients, outcomes have significantly improved over time, with significant reductions in operative mortality and perioperative complications...
October 3, 2017: Circulation
https://www.readbyqxmd.com/read/28964414/bilateral-internal-mammary-artery-use-can-be-safely-taught-without-increasing-morbidity-or-mortality
#10
Chetan Pasrija, Mehrdad Ghoreishi, Aakash Shah, Michael Rouse, James S Gammie, Zachary N Kon, Bradley S Taylor
BACKGROUND: Evidence shows a likely survival benefit with the use of bilateral internal mammary arteries (BIMA) compared with a single internal mammary artery (SIMA). Nonetheless, BIMA use is often not used or taught because of a perceived increase in operative time and complexity. This study aimed to evaluate operative time, morbidity, and mortality in both resident and nonresident cases using BIMA compared with SIMA. METHODS: Consecutive patients undergoing isolated coronary artery bypass grafting (October 2012 to April 2015) at a single institution were reviewed...
September 27, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28958083/no-improvements-in-long-term-outcome-after-coronary-artery-bypass-grafting-with-arterial-grafts-as-a-second-conduit-a-swedish-nationwide-registry-study
#11
Mikael Janiec, Axel Dimberg, Timo Z Nazari Shafti, Bo Lagerqvist, Rickard P F Lindblom
OBJECTIVES: Coronary artery bypass grafting using saphenous vein grafts (SVGs) in addition to the left internal mammary artery (IMA) graft is vitiated by poor long-term patency of the vein grafts. Hypothetically, the increased use of arterial grafts could confer even better outcomes. Our goal was to evaluate results after coronary artery bypass grafting in Sweden, where arterial grafts were used as a second conduit. METHODS: Within the Swedish Web System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART) registry, we identified patients who had coronary artery bypass grafting from 2001 to 2015 using the IMA and the SVG, the radial artery (RA) or the additional IMA [bilateral IMA (BIMA)] as a second conduit...
August 28, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28958050/a-second-arterial-conduit-to-the-circumflex-circulation-significantly-improves-survival-after-coronary-artery-bypass-surgery
#12
Suvitesh Luthra, Miguel M Leiva-Juárez, Anil John, Maciej Matuszewski, Ian S Morgan, John S Billing
OBJECTIVES: Conventional coronary artery bypass surgery involves the use of a single left internal mammary artery to the left anterior descending artery and saphenous vein grafts reserved for other sites. This retrospective propensity-matched study investigated the impact of a second arterial conduit to the left-sided circulation on early and long-term survival after coronary artery bypass surgery. METHODS: Data were retrospectively collected from 2004 to 2014 for all revascularizations with at least 1 arterial and/or 1 venous graft to the circumflex circulation, in addition to an internal mammary artery to the left anterior descending artery...
September 12, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28955074/internal-mammary-artery-flow-in-different-racial-groups-of-pakistan
#13
Mudassir Iqbal Dar, Asim Hassan Dar, Mansoor Ahmed, Abdul Haseeb, Muhammad Bilal
OBJECTIVE: To find out any differences in free flow of internal mammary artery among different ethnic groups. METHODS: This observational, cross-sectional study was conducted at the Civil Hospital, Karachi, from January 2013 to December 2015, and comprised patients who underwent coronary artery bypass grafting. The participants were divided into 5 groups, i.e. Sindhi, Muslim migrants from India, Punjabi, Pathan and Balochi patients. Free flow of internal mammary artery was measured immediately after harvesting within a syringe, and its flow was measured in 30 seconds...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28954599/complete-recovery-of-string-sign-of-the-internal-mammary-artery-graft-11-years-after-coronary-artery-bypass-surgery-associated-with-disparition-of-competitive-flow
#14
François Simon, Antoine Guedes, Claude Hanet
No abstract text is available yet for this article.
September 28, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28935967/mircrorna-19a-promotes-vascular-inflammation-and-foam-cell-formation-by-targeting-hbp-1-in-atherogenesis
#15
Heming Chen, Xiaoyi Li, Shuiyi Liu, Lu Gu, Xinmin Zhou
Atherosclerosis, a serious threat to human cardiovascular health, involves inflammation throughout its various stages of development. MicroRNAs play an important regulatory role in macrophages that respond to inflammation, but the underlying mechanisms are largely unknown. In this work, we study the impact of miR-19a in macrophage-derived foam cell formation during atherogenesis. A microarray-based analysis of serums from patients with coronary heart disease in comparison with healthy controls reveals a significant enrichment of miR-19a in the serums of atherosclerosis patients...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28935322/off-pump-double-coronary-artery-bypass-in-a-14-year-old-with-kawasaki-disease
#16
Michael D Fridman, Carl Y Owada, Richard D Gregory, Peter L Birnbaum
A 14-year-old male patient with a history of atypical Kawasaki disease at age 2 presents with triple vessel giant coronary aneurysms. Over the last several years, he began experiencing angina and dyspnea on exertion, which was a result of fully occluded right coronary and left circumflex arteries and 90% stenosis in the left anterior descending artery. He underwent off-pump coronary artery bypass using the left and right internal mammary arteries. At 18-month follow-up, there is no evidence of ischemia. Off-pump bypass is a feasible option for surgical management of the stenotic and occlusive complications of Kawasaki disease...
October 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28915211/minimally-invasive-laparoscopic-dissected-deep-inferior-epigastric-artery-perforator-flap-mild-diep-an-anatomic-feasibility-study-and-a-first-clinical-case
#17
Mikael Hivelin, Antoine Soprani, Nathaniel Schaffer, Stéphane Hans, Laurent Lantieri
The deep inferior epigastric perforator (DIEP) flap is a workhorse of breast reconstruction. Risks of herniation derive from violation of the rectus abdominis muscle anterior rectus sheath (ARS) and might be reduced by Minimally Invasive Laparoscopic Dissection (MILD) of the deep inferior epigastric vessels. We performed a feasibility study on five anatomical subjects and performed a secondary right breast reconstruction on a 67 year-old woman. A 30° laparoscope was used with laparoscopy ports inset to preserve the flap...
September 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28901321/supplemental-conventional-transarterial-embolization-chemoembolization-therapy-via-extrahepatic-arteries-for-hepatocellular-carcinoma
#18
Yuanqan Huang, Zhongzhi Jia, Jianfei Tu, Tao Shen, Feng Tian, Guomin Jiang
PURPOSE: To assess the value of conventional transarterial embolization/chemoembolization (cTAE/TACE) therapy via extrahepatic arteries for patients with unresectable hepatocellular carcinoma (HCC). METHODS: Patients with unresectable HCC who underwent cTAE/TACE therapy via extrahepatic arteries between May 2008 and July 2016 across 4 medical centers were identified. The technical success, serum alpha-fetoprotein (AFP) levels changes, tumor response, disease control rate, survival rate, and major complication were analyzed...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28890056/giant-chest-wall-arteriovenous-malformation-a-case-report-and-literature-review
#19
Cullen McCarthy, Subrato Deb, Suhair Maqusi, Joshua Gierman
INTRODUCTION: We present an interesting case of a 55 year-old male with a large left chest mass after significant cutaneous bleeding. CT angiogram of the chest revealed arteriovenous malformation with blood supply from subbranches of the left subclavian artery, left internal mammary artery and left external carotid artery. Measuring 5.0x14.0x10.8cm, the mass extended superior to the clavicle and inferior to the third rib with medial and lateral borders at the level of the clavicular head and coracoid, respectively...
September 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28884387/genome-wide-dna-methylation-patterns-in-coronary-heart-disease
#20
X Wang, A-H Liu, Z-W Jia, K Pu, K-Y Chen, H Guo
BACKGROUND: To better understand the molecular mechanisms of atherosclerosis, we conducted a comparative analysis of DNA methylation patterns in right coronary arteries in the area of advanced atherosclerotic plaques (CAP), great saphenous vein (GSV), and internal mammary artery (IMA) of patients affected by coronary heart disease. METHODS: DNA methylation data (accession number E‑GEOD-62867) were divided into three paired groups: CAP vs. IMA, CAP vs. GSV, and IMA vs...
September 7, 2017: Herz
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