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https://www.readbyqxmd.com/read/29424733/decreased-fendrr-and-lincrna-p21-expression-in-atherosclerotic-plaque
#1
Nilgün Çekin, Arzu Özcan, Sabahattin Göksel, Serdal Arslan, Ergün Pınarbaşı, Öcal Berkan
OBJECTIVE: Cardiovascular diseases are the most important cause of mortality worldwide, particularly atherosclerosis. Recently, lncRNAs affecting atherosclerotic progression have been reported in vascular smooth muscle cells, endothelial cells, and monocytes, suggesting that lncRNAs play an important role in atherosclerosis. METHODS: In recent clinical studies, nowadays, it was determined that internal mammary bypass grafts are closest to ideal grafts in coronary artery bypass surgery...
February 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29413876/scoring-system-to-guide-decision-making-for-the-use-of-bilateral-internal-mammary-arteries-the-bima-score
#2
Shahzad G Raja, Umberto Benedetto
OBJECTIVE: Currently, surgeons are unable to estimate whether the survival benefit from bilateral internal mammary artery (BIMA) grafting outweighs the increased deep sternal infection (DSWI) risk in the individual cases. As a consequence BIMA grafting is still largely underutilized. We aimed to develop and validate a scoring system to predict the individual risk for DSWI and 10 year survival probability to guide surgeons in decision making process for the use of BIMA over single internal mammary artery (SIMA)...
January 26, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29412699/identification-of-differential-gene-expression-patterns-in-human-arteries-from-patients-with-chronic-kidney-disease
#3
Jane Stubbe, Vibe Skov, Helle Charlotte Thiesson, Karl Egon Larsen, Maria Lyck Hansen, Boye L Jensen, Bente Jespersen, Lars M Rasmussen
BACKGROUND: Uremia accelerates atherosclerosis but little is known about affected pathways in human vasculature. This study aimed to identify differentially expressed arterial transcripts in patients with chronic kidney disease (CKD) Methods: Global mRNA expression was estimated by microarray hybridization in iliac arteries (n=14) from renal transplant recipients and compared with renal arteries from healthy living kidney donors (n=19) in study 1. Study 2 compared non-atherosclerotic internal mammary arteries (IMA) from five patients with elevated plasma creatinine levels and age and gender matched controls with normal levels...
February 7, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29410264/early-outcome-of-bilateral-versus-single-internal-mammary-artery-grafting-in-the-elderly
#4
Antonino S Rubino, Giuseppe Gatti, Daniel Reichart, Tuomas Tauriainen, Marisa De Feo, Francesco Onorati, Aniello Pappalardo, Sidney Chocron, Helmut Gulbins, Magnus Dalén, Peter Svenarud, Giuseppe Faggian, Ilaria Franzese, Giuseppe Santarpino, Theodor Fischlein, Daniele Maselli, Saverio Nardella, Riccardo Gherli, Aamer Ahmed, Francesco Santini, Antonio Salsano, Francesco Nicolini, Marco Zanobini, Matteo Saccocci, Vito G Ruggieri, Karl Bounader, Carmelo Mignosa, Paola D'Errigo, Stefano Rosato, Juhani Airaksinen, Andrea Perrotti, Fausto Biancari
BACKGROUND: Bilateral internal mammary artery (BIMA) grafting is increasingly used in the elderly without evidence of its risks or benefits compared to single internal mammary artery (SIMA) grafting. METHODS: 2899 patients aged 70 years or older (855 underwent BIMA grafting, 29.5%) operated on from January 2015 to December 2016 and included in the prospective multicenter E-CABG study were considered in this analysis. RESULTS: One-to-one propensity matching resulted in 804 pairs with similar preoperative risk profile...
February 1, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29409169/coronary-artery-revascularization-in-infants-children-and-adolescents-the-internal-mammary-artery-is-still-the-conduit-of-choice
#5
Harold L Lazar
No abstract text is available yet for this article.
January 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29397129/dexmedetomidine-promotes-metastasis-in-rodent-models-of-breast-lung-and-colon-cancers
#6
H Lavon, P Matzner, A Benbenishty, L Sorski, E Rossene, R Haldar, E Elbaz, J P Cata, V Gottumukkala, S Ben-Eliyahu
BACKGROUND: Perioperative strategies can significantly influence long-term cancer outcomes. Dexmedetomidine, an α 2 -adrenoceptor agonist, is increasingly used perioperatively for its sedative, analgesic, anxiolytic, and sympatholytic effects. Such actions might attenuate the perioperative promotion of metastases, but other findings suggest opposite effects on primary tumour progression. We tested the effects of dexmedetomidine in clinically relevant models of dexmedetomidine use on cancer metastatic progression...
January 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29349438/idiopathic-internal-mammary-artery-aneurysm-in-the-setting-of-aberrant-right-subclavian-artery
#7
Tariq Almerey, Ricardo Paz-Fumagalli, Houssam Farres, Warner A Oldenburg, Albert G Hakaim
Aneurysms of the internal mammary artery are extremely rare. Immediate treatment is necessary because of the high risk of rupture that can be life-threatening. Here we describe a case of idiopathic internal mammary artery aneurysm in a 54-year-old woman in the setting of aberrant right subclavian artery. The aneurysm was successfully treated with coil embolization without complications.
December 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29338997/meta-analysis-of-the-sources-of-bleeding-after-adult-cardiac-surgery
#8
Fausto Biancari, Eeva-Maija Kinnunen, Tuomas Kiviniemi, Tuomas Tauriainen, Vesa Anttila, Juhani K E Airaksinen, Debora Brascia, Francesco Vasques
OBJECTIVE: The aim of this study was to pool data on the proportion and prognostic impact of sources of bleeding in patients requiring re-exploration after adult cardiac surgery. DESIGN: Systematic review of the literature and meta-analysis. SETTING: Multistitutional study. MEASUREMENTS AND MAIN RESULTS: A literature review was performed to identify studies published since 1990 evaluating the outcome after reoperation for bleeding or tamponade after adult cardiac surgery...
December 13, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29336392/transesophageal-echocardiography-evaluation-of-the-aortic-arch-branches
#9
REVIEW
Thimmangouda A Patil, Santosh Kumar Ambli
Visualization of aortic arch branches by transesophageal echocardiography has been technically challenging. Visualizing these vessels helps in identifying the extent of dissection of the aorta, assessing the severity of carotid artery stenosis, presence of atheromatous plaques, patency of the left internal mammary artery graft, confirmation of subclavian artery cannulation, confirming holodiastolic flow reversal in the left subclavian artery by spectral Doppler imaging in case of severe aortic regurgitation, and confirming the optimal position of the intraaortic balloon perioperatively...
January 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29331180/oh-father-where-art-we-left-internal-mammary-artery-with-greater-saphenous-vein-grafts-still-rules-surgical-coronary-revascularization-after-30%C3%A2-years
#10
EDITORIAL
Chadwick W Stouffer, Michael E Halkos
No abstract text is available yet for this article.
December 26, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29325034/ghrelin-preserves-ischemia-induced-vasodilation-of-male-rat-coronary-vessels-following-beta-adrenergic-receptor-blockade
#11
James T Pearson, Nicola Collie, Regis R Lamberts, Tadakatsu Inagaki, Misa Yoshimoto, Keiji Umetani, Philip Davis, Gerard Wilkins, Pete P Jones, Mikiyasu Shirai, Daryl O Schwenke
Acute myocardial infarction (MI) triggers an adverse increase in cardiac sympathetic nerve activity (SNA). While β-adrenergic receptor (β-AR)-blockers are routinely used for the management of MI, they may also counter β-AR-mediated vasodilation of coronary vessels. We have reported that ghrelin prevents sympathetic activation following MI. Whether ghrelin modulates coronary vascular tone following MI, either through the modulation of SNA, or directly as a vasoactive mediator, has never been addressed.We utilized synchrotron microangiography to image coronary perfusion and vessel internal diameter (ID) in anesthetized Sprague Dawley rats before, and then again 30 mins after induction of an MI (left coronary artery ligation)...
January 9, 2018: Endocrinology
https://www.readbyqxmd.com/read/29322817/endovascular-coil-embolization-and-stenting-for-the-treatment-of-iatrogenic-right-internal-mammary-artery-injury-a-case-report
#12
Zhen Jiang, JinXiu Yang, XingXiang Wang
A 54-year-old Chinese woman presented with a 10-year history of repeated paroxysmal palpitations. She was diagnosed with paroxysmal supraventricular tachycardia by 12-lead electrocardiogram and was advised to undergo catheter-based radiofrequency ablation. During the procedure, a rare complication occurred that was diagnosed as a right internal mammary artery penetrating injury. After appropriate emergency treatment with arterial embolization and membrane-covered stent implantation, the patient was out of immediate danger of haemorrhaging...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29315865/coronary-artery-bypass-grafting-in-children
#13
Ahmet Arnaz, Tayyar Sarioglu, Yusuf Yalcinbas, Ersin Erek, Riza Turkoz, Ayla Oktay, Arda Saygili, Dilek Altun, Ayse Sarioglu
BACKGROUND: We present our clinical experience with coronary artery bypass grafting (CABG) in children. METHODS: Ten children who underwent CABG between July 1995 and August 2017 were retrospectively analyzed. Data including congenital cardiac malformations, previous surgical procedures, age and sex, type of coronary complications, ischemic events preceding surgery, and ventricular function before and after CABG were recorded. RESULTS: The study population consisted of five males and five females with a median age of 2...
January 7, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29304874/total-arterial-revascularization-in-patients-with-acute-myocardial-infarction-feasibility-and-outcomes
#14
Philippe Grieshaber, Lukas Oster, Tobias Schneider, Victoria Johnson, Coskun Orhan, Peter Roth, Bernd Niemann, Andreas Böning
BACKGROUND: In acute situations such as acute myocardial infarction (AMI) with indication for coronary artery bypass grafting (CABG), total arterial revascularization (TAR) is often rejected in favour of saphenous vein (SV) grafting, which is assumed to allow for quicker vessel harvesting, a simpler anastomosis technique, and thus quicker revascularization and fewer bleeding complications. The aim of this study was to evaluate whether reluctance to apply TAR in AMI is still justified from a technical point of view in the current era and whether superiority of TAR results is also evident in emergency patients with AMI undergoing CABG...
January 5, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29300076/modified-carbodissection-a-new-technique-for-harvesting-the-internal-mammary-artery
#15
Shegu Gilbert, Devender Singh, M K Sivakumar
The modified carbodissection technique is a new technique for harvesting the internal mammary artery during coronary artery bypass graft surgery. It is performed using an improvised instrument that consists of an electrocautery device and a carbon dioxide blower/mister. It combines electrocautery dissection and continuous controlled gas blow dissection along with saline irrigation mist. Gas dissection causes vasodilation and maintains the artery in a dilated state during dissection. Saline flow reduces the amount of heat generated at the cautery site and prevents drying and desiccation of the tissues...
October 29, 2017: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/29300070/skeletonized-internal-mammary-artery-harvest-with-diathermy-and-cold-dissection
#16
Andras Durko, Edris Mahtab, Jamie Romeo, Ad Bogers
This surgical tutorial demonstrates the technique of skeletonized internal mammary artery harvesting for coronary artery bypass grafting, using diathermy and cold dissection [1]. The procedure is performed on the left internal mammary artery, but is also applicable for harvesting the right internal mammary artery.
December 12, 2017: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/29281607/cabg-a-continuing-evolution
#17
REVIEW
Faisal Bakaeen
Use of coronary artery bypass grafting (CABG) has had a resurgence, as clinical trial data emerged showing that it remains the standard of care for patients with complex lesions. Debate exists regarding various factors, including endoscopic vs open vein-graft harvesting, single vs bilateral mammary artery grafts, radial artery vs saphenous vein grafts, right internal mammary artery vs radial artery grafts, and on-pump vs off-pump surgery. More recent developments include minimally invasive approaches, robotics, and hybrid revascularization, which are changing the risk-benefit ratio for this patient population...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29279526/in-situ-skeletonized-right-internal-mammary-artery-bypass-grafting-to-left-anterior-descending-artery
#18
Qiang Ji, LiMin Xia, YunQing Shi, RunHua Ma, JinQiang Shen, Hao Lai, WenJun Ding, ChunSheng Wang
This study aimed to evaluate the feasibility and the mid-term efficacy of an in situ skeletonized right internal mammary artery (IMA) bypass grafting to a left anterior descending artery (LAD), and to determine risk factors for IMA graft failure in a single-center study.From January 2012 to December 2015, 189 patients (173 males, 50.6 ± 6.0 years old) undergoing first isolated coronary artery bypass grafting surgery with the in situ skeletonized right IMA grafting to the LAD were included in this study. Baseline characteristics, peroperative data, and follow-up outcomes were investigated and analyzed...
December 27, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29277506/high-output-cardiac-failure-and-coronary-steal-with-an-arteriovenous-fistula
#19
Amtul Aala, Sairah Sharif, Leslie Parikh, Paul C Gordon, Susie L Hu
Creation of an arteriovenous access for hemodialysis can provoke a sequence of events that significantly affects cardiovascular hemodynamics. We present a 78-year-old man with end-stage renal disease and concomitant coronary artery disease previously requiring coronary artery bypass grafting including a left internal mammary graft to the left anterior descending artery, ischemic cardiomyopathy with left ventricular systolic dysfunction, and severe aortic stenosis who developed hypotension unresponsive to medical therapy after recent angioplasty of his ipsilateral arteriovenous fistula for high-grade outflow stenosis...
December 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29273932/treatment-of-gigantomastia-using-a-medial-lateral-bipedicle-reduction-mammoplasty-the-role-of-doppler-assisted-preoperative-perforator-identification
#20
Nader Gomaa Elmelegy, Mohamed Saad Sadaka, Ahmed M Hegazy, Doaa E Abdeldaim
The purpose of this study is to introduce a breast reduction technique designed to reduce the incidence of postoperative nipple-areola complex ischemia and necrosis following reduction mammoplasty, while at the same time allowing all the other goals of breast reduction to be realized. This is achieved through preoperative detection of perforating vessels supplying the nipple-areola complex using a hand-held Doppler. The horizontally based parenchymal pedicle is designed to include these perforators whether originating from the internal mammary artery, lateral thoracic artery or both...
December 22, 2017: Aesthetic Plastic Surgery
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