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https://www.readbyqxmd.com/read/28430088/informatics-for-health-2017-advancing-both-science-and-practice
#1
Philip J Scott, Ronald Cornet, Colin McCowan, Niels Peek, Paolo Fraccaro, Nophar Geifman, Wouter T Gude, William Hulme, Glen P Martin, Richard Williams
INTRODUCTION: The Informatics for Health congress, 24-26 April 2017, in Manchester, UK, brought together the Medical Informatics Europe (MIE) conference and the Farr Institute International Conference. This special issue of the Journal of Innovation in Health Informatics contains 113 presentation abstracts and 149 poster abstracts from the congress. DISCUSSION: The twin programmes of "Big Data" and "Digital Health" are not always joined up by coherent policy and investment priorities...
April 21, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28426696/heritability-of-brain-volume-on-mri-in-middle-to-advanced-age-a-twin-study-of-japanese-adults
#2
Matthew W Lukies, Yoshiyuki Watanabe, Hisashi Tanaka, Hiroto Takahashi, Soshiro Ogata, Kayoko Omura, Shiro Yorifuji, Noriyuki Tomiyama
Brain atrophy is part of the aging process and accelerated by neurodegenerative diseases, so an understanding of the background heritability of brain volume is essential. The purpose of this study was to determine the heritability of brain volume in middle to advanced age East Asian adults, an age group less studied and an ethnicity not previously studied. 3T magnetic resonance images were obtained and volumetric analyses conducted for a total of 74 individuals, 20 monozygotic twin pairs (mean age 61y min 41y max 75y) and 17 dizygotic twin pairs (mean age 64y min 41y max 85y)...
2017: PloS One
https://www.readbyqxmd.com/read/28422613/the-impact-of-prospective-telemedicine-implementation-in-the-management-of-childhood-acute-lymphoblastic-leukemia-in-recife-brazil
#3
Francisco Pedrosa, Faisal Shaikh, Gaston Rivera, Raul Ribeiro, Ibrahim Qaddoumi
BACKGROUND: A gap in childhood cancer outcomes remains between developed and developing countries. Persistence of this gap may be caused by financial, social, or educational disparities. Twinning and distance learning initiatives may improve such disparities. Integrating telemedicine into pediatric oncology twinning programs enhances education and facilitates patient-centered capacity building. MATERIALS AND METHODS: We performed an analysis of Web-based meetings held from August 2005 through July 2009 between the International Outreach Program at St...
April 19, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28403975/-fetoscopic-laser-coagulation-in-200%C3%A2-consecutive-monochorionic-pregnancies-with-twin-twin-transfusion-syndrome
#4
L Lecointre, N Sananès, A S Weingertner, A Gaudineau, C Akladios, V Cavillon, B Langer, R Favre
OBJECTIVES: To report preoperative data, surgical characteristics, complications and perinatal outcome of twin-twin transfusion syndrome (TTTS) managed with laser ablation surgery, to analyze predictors of neonatal survival and to compare the 100 most recent cases with the older 100. MATERIALS AND METHODS: Observational cohort moncentric study of 200 cases of TTTS consecutively treated with fetoscopic laser coagulation between January 2004 and December 2014...
February 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28403844/health-and-legal-literacy-for-migrants-twinned-strands-woven-in-the-cloth-of-social-justice-and-the-human-right-to-health-care
#5
Bilkis Vissandjée, Wendy E Short, Karine Bates
BACKGROUND: Based on an analysis of published literature, this paper provides an over-view of the challenges associated with delivering on the right to access quality health care for international migrants to industrialized countries, and asks which group of professionals is best equipped to provide services that increase health and legal literacy. Both rights and challenges are approached from a social justice perspective with the aim of identifying opportunities to promote greater health equity...
April 13, 2017: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/28390446/genetic-influence-on-accessory-navicular-bone-in-the-foot-a-korean-twin-and-family-study
#6
In Yae Cheong, Hyo Jeong Kang, Hyeonyoung Ko, Joohon Sung, Yun-Mi Song, Ji Hye Hwang
An accessory navicular bone (AN) is the most common accessory ossicle in the foot. The presence of an AN bone can trigger various foot problems, such as posterior tibial tendon pathology, flattening of the medial longitudinal arch, and medial foot pain. Despite the clinical influence of presence of an AN in foot disease, the research regarding its inheritance is still insufficient. A total of 135 pairs of monozygotic (MZ) twins, 25 pairs of dizygotic (DZ) twins, and 676 singletons from families were enrolled in order to estimate genetic influences on AN...
April 9, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28384123/magnetic-resonance-imaging-with-hyperpolarized-agents-methods-and-applications
#7
Erin Adamson, Kai Ludwig, David Mummy, Sean B Fain
In the past decade, hyperpolarized (HP) contrast agents have been under active development for MRI applications to address the twin challenges of functional and quantitative imaging. Both HP helium (<sup>3</sup>He) and xenon (<sup>129</sup>Xe) gases have reached the stage where they are under study in clinical research. HP <sup>129</sup>Xe, in particular, is poised for larger scale clinical research to investigate asthma, chronic obstructive pulmonary disease, and fibrotic lung diseases...
April 6, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28370330/a-combination-test-for-detection-of-gene-environment-interaction-in-cohort-studies
#8
Brandon Coombes, Saonli Basu, Matt McGue
Identifying gene-environment (G-E) interactions can contribute to a better understanding of disease etiology, which may help researchers develop disease prevention strategies and interventions. One big criticism of studying G-E interaction is the lack of power due to sample size. Studies often restrict the interaction search to the top few hundred hits from a genome-wide association study or focus on potential candidate genes. In this paper, we test interactions between a candidate gene and an environmental factor to improve power by analyzing multiple variants within a gene...
March 31, 2017: Genetic Epidemiology
https://www.readbyqxmd.com/read/28369107/mapping-the-association-between-back-pain-and-type-2-diabetes-a-cross-sectional-and-longitudinal-study-of-adult-spanish-twins
#9
Amabile Dario, Manuela Ferreira, Kathryn Refshauge, Alison Harmer, Juan Sánchez-Romera, Francisco Pérez-Riquelme, Ligia Cisneros, Juan Ordoñana, Paulo Ferreira
BACKGROUND: Back pain and type 2 diabetes often co-occur, resulting in greater impact on people's health and complexity in their care. Plausible causal mechanisms for this association have been proposed, yet the nature of the link remains unclear. We therefore explored the direction of the association between type 2 diabetes and chronic back pain in twins, controlling for genetics and early environmental confounding. METHODS: 2,096 and 1,098 twins were included in the cross-sectional and longitudinal analyses, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28368150/genetic-and-environmental-influences-on-diagnostic-and-statistical-manual-of-mental-disorders-fifth-edition-dsm-5-maladaptive-personality-traits-and-their-connections-with-normative-personality-traits
#10
Zara E Wright, Shandell Pahlen, Robert F Krueger
The Diagnostic and Statistical Manual for Mental Disorders-Fifth Edition (DSM-5) proposes an alternative model for personality disorders, which includes maladaptive-level personality traits. These traits can be operationalized by the Personality Inventory for the DSM-5 (PID-5). Although there has been extensive research on genetic and environmental influences on normative level personality, the heritability of the DSM-5 traits remains understudied. The present study addresses this gap in the literature by assessing traits indexed by the PID-5 and the International Personality Item Pool NEO (IPIP-NEO) in adult twins (N = 1,812 individuals)...
April 3, 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28351882/rahi-sathi-indo-u-s-collaboration-the-evolution-of-a-trainee-led-twinning-model-in-global-health-into-a-multidisciplinary-collaborative-program
#11
Apurv Soni, Nisha Fahey, Abraham Jaffe, Shyamsundar Raithatha, Nitin Raithatha, Anusha Prabhakaran, Tiffany A Moore Simas, Nancy Byatt, Jagdish Vankar, Michael Chin, Ajay G Phatak, Shirish Srivastava, David D McManus, Eileen O'Keefe, Harshil Patel, Niket Patel, Dharti Patel, Michaela Tracey, Jasmine A Khubchandani, Haley Newman, Allison Earon, Hannah Rosenfield, Anna Handorf, Brittany Novak, John Bostrom, Anindita Deb, Soaham Desai, Dipen Patel, Archana Nimbalkar, Kandarp Talati, Milagros Rosal, Patricia McQuilkin, Himanshu Pandya, Heena P Santry, Sunil Thanvi, Utpala Kharod, Melissa Fischer, Jeroan Allison, Somashekhar M Nimbalkar
BACKGROUND: In recent years there has been a surge in the number of global health programs operated by academic institutions. However, most of the existing programs describe partnerships that are primarily faculty-driven and supported by extramural funding. PROGRAM DESCRIPTION: Research and Advocacy for Health in India (RAHI, or "pathfinder" in Hindi) and Support and Action Towards Health-Equity in India (SATHI, or "partnership" in Hindi) are 2 interconnected, collaborative efforts between the University of Massachusetts Medical School (UMMS) and Charutar Arogya Mandal (CAM), a medical college and a tertiary care center in rural western India...
March 24, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28347396/perceived-family-cohesion-moderates-environmental-influences-on-prosocial-behavior-in-nigerian-adolescent-twins
#12
Yoon-Mi Hur, Jeanette Taylor, Hoe-Uk Jeong, Min-Seo Park, Brett C Haberstick
Research shows that perceived family cohesion is positively related to prosocial behavior in adolescents. In this study, we investigated heritability of prosocial behavior (PB) and perceived family cohesion (FC) among Nigerian twins attending public schools in Lagos State, Nigeria (mean age = 14.7 years, SD = 1.7 years), and explored the issue of whether children's perception of cohesive family environment moderated genetic and environmental influences on (PB). The PB scale of the Strengths and Difficulties Questionnaire and the FC scale of the Family Adaptability and Cohesion Evaluation Scale III were completed by 2,376 twins (241 monozygotic (MZ) male, 354 MZ female, 440 dizygotic (DZ) male, 553 DZ female, and 788 opposite-sex DZ twins)...
March 28, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28347391/-biracial-looking-twins-a-new-twin-type-twin-research-twins-with-cystic-teratomas-sleep-quality-and-body-mass-index-previable-membrane-rupture-print-and-online-reports-twins-born-to-a-sister-surrogate-nasa-twin-study-african-cosmopolitan-twin-fashion-inspirations
#13
Nancy L Segal
Dizygotic (DZ) co-twins born to mothers and fathers from different racial or ethnic backgrounds often resemble one parent much more than the other. As such, these pairs comprise a unique subset of twins for investigating how others' responses to their different looks may affect their personalities and self-esteem. This article describes some of these twin pairs and some challenges of raising them, and suggests ways they may be used in research. Next, recent twin research on cystic teratomas, relations between sleep quality and body mass index, and previable membrane rupture is described...
March 28, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28341515/computerised-interpretation-of-fetal-heart-rate-during-labour-infant-a-randomised-controlled-trial
#14
(no author information available yet)
BACKGROUND: Continuous electronic fetal heart-rate monitoring is widely used during labour, and computerised interpretation could increase its usefulness. We aimed to establish whether the addition of decision-support software to assist in the interpretation of cardiotocographs affected the number of poor neonatal outcomes. METHODS: In this unmasked randomised controlled trial, we recruited women in labour aged 16 years or older having continuous electronic fetal monitoring, with a singleton or twin pregnancy, and at 35 weeks' gestation or more at 24 maternity units in the UK and Ireland...
March 21, 2017: Lancet
https://www.readbyqxmd.com/read/28337341/aetiological-influences-on-stability-and-change-in-emotional-and-behavioural-problems-across-development-a-systematic-review
#15
L J Hannigan, N Walaker, M A Waszczuk, T A McAdams, T C Eley
Emotional and behavioural problems in childhood and adolescence can be chronic and are predictive of future psychiatric problems. Understanding what factors drive the development and maintenance of these problems is therefore crucial. Longitudinal behavioural genetic studies using twin, sibling or adoption data can be used to explore the developmental aetiology of stability and change in childhood and adolescent psychopathology. We present a systematic review of longitudinal, behavioural genetic analyses of emotional and behavioural problems between ages 0 to 18 years...
2017: Psychopathology Review
https://www.readbyqxmd.com/read/28303775/reared-apart-chinese-twins-chance-discovery-twin-based-research-twin-study-of-media-use-twin-relations-over-the-life-span-breast-feeding-opposite-sex-twins-print-and-online-media-twins-in-fashion-second-twin-pair-born-to-tennis-star-twin-primes-twin-pandas
#16
Nancy L Segal
A January 2017 reunion of 10-year-old reared-apart Chinese twin girls was captured live on ABC's morning talk show Good Morning America, and rebroadcast on their evening news program Nightline. The twins' similarities and differences, and their participation in ongoing research will be described. This story is followed by reviews of twin research concerning genetic and environmental influences on media use, twin relations across the lifespan and the breast-feeding of opposite-sex twins. Popular interest items include twins in fashion, the second twin pair born to an internationally renowned tennis star, twin primes and twin pandas...
April 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28302734/time-dependent-genetic-effects-on-gene-expression-implicate-aging-processes
#17
Julien Bryois, Alfonso Buil, Pedro G Ferreira, Nikolaos I Panousis, Andrew A Brown, Ana Viñuela, Alexandra Planchon, Deborah Bielser, Kerrin Small, Tim Spector, Emmanouil T Dermitzakis
Gene expression is dependent on genetic and environmental factors. In the last decade, a large body of research has significantly improved our understanding of the genetic architecture of gene expression. However, it remains unclear whether genetic effects on gene expression remain stable over time. Here, we show, using longitudinal whole-blood gene expression data from a twin cohort, that the genetic architecture of a subset of genes is unstable over time. In addition, we identified 2213 genes differentially expressed across time points that we linked with aging within and across studies...
April 2017: Genome Research
https://www.readbyqxmd.com/read/28301762/sex-differences-in-binge-eating-gonadal-hormone-effects-across-development
#18
Kelly L Klump, Kristen M Culbert, Cheryl L Sisk
Eating disorders are highly sexually differentiated disorders that exhibit a female predominance in risk. Most theories focus on psychosocial explanations to the exclusion of biological/genetic influences. The purpose of this descriptive review is to evaluate evidence from animal and human studies in support of gonadal hormone effects on sex differences in binge eating. Although research is in its nascent stages, findings suggest that increased prenatal testosterone exposure in males appears to protect against binge eating...
March 16, 2017: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/28296242/observed-parent-child-feeding-dynamics-in-relation-to-child-body-mass-index-and-adiposity
#19
C M Johnson, M S Henderson, G Tripicchio, P Rozin, M Heo, A Pietrobelli, R I Berkowitz, K L Keller, M S Faith
BACKGROUND: Restrictive feeding is associated with child overweight; however, the majority of studies used parent-report questionnaires. OBJECTIVES: The relationship between child adiposity measures and directly observed parent and child behaviours were tested using a novel behavioural coding system (BCS). METHODS: Data from 109 children, participants in a twin study and their mothers, were analyzed. Parent-child dyads were video-recorded twice in the laboratory, while children ate ad libitum from a buffet lunch...
March 10, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28290499/the-evolution-of-extreme-cooperation-via-shared-dysphoric-experiences
#20
Harvey Whitehouse, Jonathan Jong, Michael D Buhrmester, Ángel Gómez, Brock Bastian, Christopher M Kavanagh, Martha Newson, Miriam Matthews, Jonathan A Lanman, Ryan McKay, Sergey Gavrilets
Willingness to lay down one's life for a group of non-kin, well documented historically and ethnographically, represents an evolutionary puzzle. Building on research in social psychology, we develop a mathematical model showing how conditioning cooperation on previous shared experience can allow individually costly pro-group behavior to evolve. The model generates a series of predictions that we then test empirically in a range of special sample populations (including military veterans, college fraternity/sorority members, football fans, martial arts practitioners, and twins)...
March 14, 2017: Scientific Reports
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