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https://www.readbyqxmd.com/read/28102741/tutorial-on-biostatistics-linear-regression-analysis-of-continuous-correlated-eye-data
#1
Gui-Shuang Ying, Maureen G Maguire, Robert Glynn, Bernard Rosner
PURPOSE: To describe and demonstrate appropriate linear regression methods for analyzing correlated continuous eye data. METHODS: We describe several approaches to regression analysis involving both eyes, including mixed effects and marginal models under various covariance structures to account for inter-eye correlation. We demonstrate, with SAS statistical software, applications in a study comparing baseline refractive error between one eye with choroidal neovascularization (CNV) and the unaffected fellow eye, and in a study determining factors associated with visual field in the elderly...
January 19, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28101403/quantitative-assessment-of-hemodynamic-and-structural-characteristics-of-in-vivo-brain-tissue-using-total-diffuse-reflectance-spectrum-measured-in-a-non-contact-fashion
#2
Yinchen Song, Sarahy Garcia, Yisel Frometa, Jessica C Ramella-Roman, Mohammad Soltani, Mohamed Almadi, Jorge J Riera, Wei-Chiang Lin
Here we present a new methodology that investigates the intrinsic structural and hemodynamic characteristics of in vivo brain tissue, in a non-contact fashion, and can be easily incorporated in an intra-operative environment. Within this methodology, relative total diffuse reflectance spectra (RTD(λ)) were acquired from targets using a hybrid spectroscopy imaging system. A spectral interpretation algorithm was subsequently applied to RTD(λ) to retrieve optical properties related to the compositional and structural characteristics of each target...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28100480/detection-of-posterior-vortex-veins-in-eyes-with-pathologic-myopia-by-ultra-widefield-indocyanine-green-angiography
#3
Muka Moriyama, Kejia Cao, Satoko Ogata, Kyoko Ohno-Matsui
AIMS: To analyse the characteristics of posterior vortex veins detected in highly myopic eyes by wide-field indocyanine green angiography (ICGA). METHODS: One hundred and fifty-eight consecutive patients (302 eyes) with high myopia (myopic refractive error >8.0 dioptres (D) or axial length ≥26.5 mm) were studied. Wide-field ICGA was performed with the Spectralis HRA module. RESULTS: Posterior vortex veins were found in 80 eyes (26%)...
January 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28099283/the-characteristics-of-excimer-laser-refractive-surgery-candidates
#4
Hassan Hashemi, Mehdi Khabazkhoob, Reza Pakzad, Abbasali Yekta, Marzieh Nojomi, Payam Nabovati
PURPOSE: To determine the demographic and refractive characteristics of excimer laser refractive surgery candidates in Iran. METHODS: This was a cross-sectional study between 2010 and 2014. All information was collected from 28 centers randomly selected from 12 provinces. Then, for each season of the year, one week was chosen through simple random selection, and within each week, 3 days were again chosen randomly. All excimer laser surgical procedures performed during these 3 days were identified by training staff, and data were extracted from patient charts...
January 17, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28092397/update-on-orthokeratology-in-managing-progressive-myopia-in-children-efficacy-mechanisms-and-concerns
#5
Xintong Li, Ilana B Friedman, Norman B Medow, Cheng Zhang
Myopia is an important public health issue, and high myopia may lead to severe complications if left untreated. Orthokeratology lenses, worn overnight to reshape the cornea, are one of many recent modalities used to slow down the progression of myopia in children. This treatment has been proven successful, as evidenced by decreased spherical refractive error and axial length relative to the control at interval follow-up ranging from 6 months to 5 years. In this systematic review, the authors collected published controlled studies that analyzed the efficacy of orthokeratology lens wear and calculated longitudinal relative changes in axial length, revealing a weighted average of -45...
January 13, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28091746/-improvement-of-vision-through-perceptual-learning-in-the-case-of-refractive-errors-and-presbyopia-a-critical-valuation
#6
S P Heinrich
The idea of compensating or even rectifying refractive errors and presbyopia with the help of vision training is not new. For most approaches, however, scientific evidence is insufficient. A currently promoted method is "perceptual learning", which is assumed to improve stimulus processing in the brain. The basic phenomena of perceptual learning have been demonstrated by a multitude of studies. Some of these specifically address the case of refractive errors and presbyopia. However, many open questions remain, in particular with respect to the transfer of practice effects to every-day vision...
January 13, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28090595/a-case-of-coats-disease-and-concurrent-anisometropic-amblyopia
#7
Nathan G Lambert, Robert O Hoffman, M Elizabeth Hartnett
PURPOSE: The aim of this report was to demonstrate a case of Coats disease in a patient with concurrent anisometropic amblyopia. OBSERVATIONS: A 10-year-old boy was diagnosed with Coats disease during routine ophthalmic examination. Visual acuity was 20/20 OD and 20/50 OS with cycloplegic refraction of +1.25 (OD) and +3.25 (OS). Examination under anesthesia showed macular exudates in the left eye that encroached near the fovea superotemporally. Despite the poor visual acuity and macular exudates, the foveal architecture of both eyes appeared normal on spectral domain optical coherence tomography...
December 2016: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/28089744/predictors-of-surgical-success-in-patients-with-intermittent-exotropia
#8
Di Zou, Clémentine Casafina, Alex Whiteman, Saurabh Jain
BACKGROUND: In patients with moderate- to large-angle exotropic deviations, surgical correction remains the definitive treatment. The purpose of this study was to identify preoperative factors that correlate with surgical success and to produce a binomial model that predicts success based on preoperative factors. METHODS: We performed a retrospective review of patients with intermittent exotropia who underwent uniocular recession-resection surgery. Success was defined as ocular deviation ≤10(Δ) exotropia and ≤5(Δ) esotropia at distance at last follow-up (at least 3 months' postoperatively)...
January 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28088605/comparison-of-the-anterior-chamber-angle-structure-between-children-and-adults
#9
Yukiko Shimizu, Shunsuke Nakakura, Toshihiko Nagasawa, Akiko Okamoto, Hitoshi Tabuchi, Yoshiaki Kiuchi
PURPOSE: To investigate the anterior chamber structure in children and adults with a similar axial length (AL). METHODS: A total of 50 children (mean age, 7.1 ± 3.3 years; range, 3-16) with mainly refractive error and 50 adults (mean age, 73.7 ± 7.8 years; range, 50-85) with short AL were included. The mean AL was 22.21 ± 0.88 mm (range, 20.67-23.97 mm) in children; 22.34 ± 0.53 mm (range, 20.50-22.96 mm), in adults. The corneal curvature, spherical equivalent, AL, central corneal thickness (CCT), inter-scleral spur distance, perpendicular distance, anterior chamber depth (ACD), angle opening distance (AOD), and lens vault were measured...
January 11, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28077157/clinical-biochemical-and-molecular-characteristics-of-filipino-patients-with-mucopolysaccharidosis-type-ii-hunter-syndrome
#10
Mary Anne D Chiong, Daffodil M Canson, Mary Ann R Abacan, Melissa Mae P Baluyot, Cynthia P Cordero, Catherine Lynn T Silao
BACKGROUND: Mucopolysaccharidosis type II, an X-linked recessive disorder is the most common lysosomal storage disease detected among Filipinos. This is a case series involving 23 male Filipino patients confirmed to have Hunter syndrome. The clinical and biochemical characteristics were obtained and mutation testing of the IDS gene was done on the probands and their female relatives. RESULTS: The mean age of the patients was 11.28 (SD 4.10) years with an average symptom onset at 1...
January 11, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28068448/photorefractive-keratectomy-with-mitomycin-c-in-meesmann-s-epithelial-corneal-dystrophy
#11
Ramon Coral Ghanem, André Luís Piccinini, Vinícius Coral Ghanem
PURPOSE: To describe a case of Meesmann's epithelial corneal dystrophy that underwent photorefractive keratectomy (PRK) with mitomycin C. METHODS: Case report. RESULTS: A 36-year-old woman was evaluated for refractive surgery. She had a history of recurrent epithelial erosions and moderate visual loss over the past 10 years. Biomicroscopy revealed bilateral micro-cystic epithelial lesions and a diagnosis of Meesmann's epithelial corneal dystrophy was proposed...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28068446/change-of-capsulotomy-over-1-year-in-femtosecond-laser-assisted-cataract-surgery-and-its-impact-on-visual-quality
#12
Christophe Panthier, Florent Costantini, Jean Claude Rigal-Sastourné, Antoine Brézin, Chadi Mehanna, Mikael Guedj, Dominique Monnet
PURPOSE: To compare the shape of the capsulotomy, its change, and its impact on visual quality over 1 year using the femtosecond laser system from the manual technique. METHODS: In this two-center cross-sectional study from May 2012 to June 2013, each patient had femtosecond laser-assisted cataract surgery in one eye (FLACS group) and conventional phacoemulsification cataract surgery in the other eye (CPCS group). An evaluation of the capsulotomy was performed using retroillumination slit-lamp photographs at 7 days, 6 months, and 1 year after surgery...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28068441/changes-in-astigmatism-densitometry-and-aberrations-after-smile-for-low-to-high-myopic-astigmatism-a-12-month-prospective-study
#13
Iben Bach Pedersen, Anders Ivarsen, Jesper Hjortdal
PURPOSE: To evaluate 12-month changes in refraction, visual outcome, corneal densitometry, and postoperative aberrations after small incision lenticule extraction (SMILE) for myopic astigmatism. METHODS: This 12-month prospective clinical trial comprised 101 eyes (101 patients) treated with SMILE for myopic astigmatism with cylinder of 0.75 to 4.00 diopters (D). The preoperative, 1-week, and 1-, 3-, 6-, 9-, and 12-month examinations included measurement of manifest refraction, uncorrected distance visual acuity (UDVA), and corrected (CDVA) distance visual acuity...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28060144/effect-of-overnight-wear-orthokeratology-lenses-on-corneal-shape-and-tears
#14
Jian Li, Ping Dong, Hu Liu
OBJECTIVE: The aim of this study was to explore the effects of the overnight wear orthokeratology (OK) lenses on corneal shape and tear film stability. METHODS: Forty patients with myopia aged between 11 and 18 years who wore OK lens continuously for more than 1 year were selected. Refractive error (D), corneal curvature, corneal surface regularity index (SRI), tear breakup time (TBUT), Schirmer I test score, and corneal staining were measured at the following time points: 1 week before wearing the OK lens (T0) and 1 week (T1), 1 month (T2), 3 months (T3), 6 months (T4), and 12 months (T5) after wear...
January 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28060059/efficacy-of-intrastromal-corneal-ring-segments-combined-with-flash-collagen-cross-linking-in-keratoconus
#15
Carlos H Gordillo, Juan C Grandin, Roger Zaldivar, Roberto Zaldivar, Adriana C Lotfi
PURPOSE: To evaluate outcomes, efficacy, and safety of intrastromal corneal ring segment implantation for treatment of keratoconus combined with collagen cross-linking (CXL) with 1-year follow-up. METHODS: One hundred nineteen eyes of 82 patients with keratoconus (37 females) underwent femtosecond (Intralase FS; Abbott Medical Optics, Inc) laser-assisted intrastromal corneal ring segment implantation (INTRASEG; Gamma Vision) with flash CXL (18 mW/cm for 5 minutes)...
February 2017: Cornea
https://www.readbyqxmd.com/read/28058149/surgical-indications-and-clinical-results-of-patients-with-exchanged-intraocular-lenses-in-a-tertiary-eye-hospital
#16
Sevim Kavuncu, Aslıhan Esra Omay, Mehmet Hakan Tırhış, Pelin Yılmazbaş
OBJECTIVES: To evaluate the demographics, surgical indications and clinical results of patients with repositioned or explanted intraocular lens (IOL) in a tertiary referral eye hospital. MATERIALS AND METHODS: Forty-eight eyes of 48 patients that underwent surgery to exchange or reposition the IOL at Ulucanlar Eye Training and Research Hospital between 2009 and 2013 were included in the study. Medical records of patients were evaluated for surgical indications, time elapsed since initial operation, preoperative and postoperative best corrected distance visual acuity and the presence of ocular disease...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28054213/visual-outcome-and-refractive-status-in-first-3%C3%A2-years-of-age-in-preterm-infants-suffered-from-laser-treated-type-1-retinopathy-of-prematurity-rop-a-6-year-retrospective-review-in-a-tertiary-centre-in-hong-kong
#17
Julie Y C Lok, Wilson W K Yip, Abbie S W Luk, Joyce K Y Chin, Henry H W Lau, Alvin L Young
PURPOSE: To report the visual outcome and refractive status in first 3 years of age in preterm infants suffered from laser-treated Type 1 retinopathy of prematurity (ROP): a 6-year review in Hong Kong DESIGN: Retrospective case series METHODOLOGY: Clinical records of all infants suffered from Type 1 ROP who had undergone laser therapy between 2007 and 2012 were retrospectively reviewed. Basic demographic data, serial changes of refractive error, visual acuity, severity of ROP and laser were analyzed...
January 4, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28050460/profile-of-amblyopia-in-school-going-5-15-years-children-at-state-level-referral-hospital-in-uttarakhand
#18
Manisha Gupta, Sudhir Kumar Rana, Sanjiv Kumar Mittal, R N P Sinha
INTRODUCTION: Amblyopia is one of the common causes of childhood visual impairment. The prevalence of amblyopia usually varies according to the age group of the studied population and the factors prevailing in that region. The upper limit of the critical time when amblyopia can develop is around eight years of age and it can be permanent if corrective measures are not taken in time. AIM: The purpose of study was to know the profile and pattern of amblyopia in children aged 5-15 years with refractive error in Uttarakhand and to compare it with national and regional (South Asian) studies...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050321/comparison-of-anterior-segment-measurements-obtained-by-aladdin-optical-biometer-and-sirius-corneal-topography
#19
Onur Polat, Zeki Baysal, Serkan Özcan, Sibel İnan, Ümit Übeyt İnan
OBJECTIVES: To assess the agreement of anterior segment parameter measurements derived from Aladdin optical biometer using optical low coherence interferometer and Sirius corneal topography using combined Scheimpflug-Placido disk. MATERIALS AND METHODS: Data obtained using the Aladdin and Sirius systems from 110 eyes of 59 subjects who had no health problems other than refractive errors were retrospectively evaluated. Anterior chamber depth (ACD), flat (K1) and steep (K2) keratometry readings, and white-to-white distance (WTW) measurements taken with both devices were noted...
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28050320/changes-in-anterior-chamber-depth-after-phacoemulsification-in-pseudoexfoliative-eyes-and-their-effect-on-accuracy-of-intraocular-lens-power-calculation
#20
Sirel Gür Güngör, Ahmet Akman, Leyla Asena, Mustafa Aksoy, Almila Sarıgül Sezenöz
OBJECTIVES: To compare anterior chamber depth (ACD) changes after phacoemulsification surgery in patients with pseudoexfoliation syndrome (PEX) and normal patients using an anterior segment imaging method. Another aim of this study was to evaluate the effect of these changes on the accuracy of intraocular lens (IOL) power calculation and postoperative refraction. MATERIALS AND METHODS: Twenty-two eyes of 22 patients with PEX and 30 eyes of 30 normal patients who underwent uneventful phacoemulsification surgery and IOL implantation were included in the study...
December 2016: Turkish Journal of Ophthalmology
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