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https://www.readbyqxmd.com/read/29353315/whole-grain-intakes-in-irish-adults-findings-from-the-national-adults-nutrition-survey-nans
#1
Clare B O'Donovan, Niamh F Devlin, Maria Buffini, Janette Walton, Albert Flynn, Michael J Gibney, Anne P Nugent, Breige A McNulty
PURPOSE: Observational studies link high whole grain intakes to reduced risk of many chronic diseases. This study quantified whole grain intakes in the Irish adult population and examined the major contributing sources. It also investigated potential dietary strategies to improve whole grain intakes. METHODS: Whole grain intakes were calculated in a nationally representative sample of 1500 Irish adults using data from the most recent national food survey, the National Adult Nutrition Survey (NANS)...
January 20, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29340736/risk-factors-for-early-infection-following-hemiarthroplasty-in-elderly-patients-with-a-femoral-neck-fracture
#2
Dirk Zajonz, Alexander Brand, Christian Lycke, Orkun Özkurtul, Jan Theopold, Ulrich J A Spiegl, Andreas Roth, Christoph Josten, Johannes K M Fakler
PURPOSE: Periprosthetic joint infections (PJI) after hemiarthroplasty for geriatric femoral neck fractures are a devastating complication that results in serious morbidity and increased mortality. Identifying risk factors associated with early infection after HA for hip fractures may offer an opportunity to address and prevent this complication in many patients. The aim of this study was to evaluate preoperative risk factors for early PJI after HA in hip fracture patients. METHODS: From January 2010 to December 2015, 312 femoral neck fractures (AO/OTA 31-B) in 305 patients were included in this single-center, retrospective study...
January 16, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29326391/zoonotic-bacteria-and-parasites-found-in-raw-meat-based-diets-for-cats-and-dogs
#3
Freek P J van Bree, Gertie C A M Bokken, Robin Mineur, Frits Franssen, Marieke Opsteegh, Joke W B van der Giessen, Len J A Lipman, Paul A M Overgaauw
Feeding raw meat-based diets (RMBDs) to companion animals has become increasingly popular. Since these diets may be contaminated with bacteria and parasites, they may pose a risk to both animal and human health. The purpose of this study was to test for the presence of zoonotic bacterial and parasitic pathogens in Dutch commercial RMBDs. We analysed 35 commercial frozen RMBDs from eight different brands. Escherichia coli serotype O157:H7 was isolated from eight products (23 per cent) and extended-spectrum beta-lactamases-producing E coli was found in 28 products (80 per cent)...
January 13, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29323612/pharmacokinetic-analysis-of-intraocular-penetration-of-latanoprost-solutions-with-different-preservatives-in-human-eyes
#4
Yuko Sekine, Marie Shimada, Shoko Satake, Masato Okubo, Akihiro Hisaka, Tadashi Hara, Megumi Honjo, Makoto Aihara
OBJECTIVES: To investigate the effect of excipients on latanoprost penetration into the aqueous humor with clinically available 6 products with different solutions mainly in the types and concentrations of preservatives. METHODS: In 363 patients with cataracts, we instilled 1 latanoprost drop in 1 eye before surgery. The drop was randomly selected by brand name product (A) and 5 generic products (B-F) composed with different excipients. B contains similar excipients to A...
January 11, 2018: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29321911/low-genetic-variation-of-invasive-fallopia-spp-in-their-northernmost-european-distribution-range
#5
Anne-Kari Holm, Abdelhameed Elameen, Benedikte W Oliver, Lars O Brandsæter, Inger S Fløistad, May B Brurberg
Knowledge about the reproduction strategies of invasive species is fundamental for effective control. The invasive Fallopia taxa (Japanese knotweed s.l.) reproduce mainly clonally in Europe, and preventing spread of vegetative fragments is the most important control measure. However, high levels of genetic variation within the hybrid F. × bohemica indicate that hybridization and seed dispersal could be important. In Norway in northern Europe, it is assumed that these taxa do not reproduce sexually due to low temperatures in the autumn when the plants are flowering...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29297137/concurrent-diffuse-large-b-cell-lymphoma-and-epstein-barr-virus-associated-smooth-muscle-tumour-in-the-small-bowel-of-an-hiv-positive-adult-a-case-report-and-review-of-the-literature
#6
C Bruce-Brand, N Mohamed, S Botes, W D Bates
No abstract text is available yet for this article.
January 3, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29280300/situation-analysis-of-procurement-and-production-of-multiple-micronutrient-supplements-in-12-lower-and-upper-middle-income-countries
#7
Eva C Monterrosa, Kalpana Beesabathuni, Kesso G van Zutphen, Georg Steiger, Roland Kupka, Alison Fleet, Klaus Kraemer
Globally, there are few vitamin and mineral ingredient manufacturers. To support local, in-country or regional procurement and production of multiple micronutrient supplements (MMS), the following production scenarios are possible: (a) straight ingredients of vitamins and minerals forms imported or locally produced that are mixed, tableted, or encapsulated and packaged by a local manufacturer; (b) import or local production of a vitamin and minerals premix that is tableted or encapsulated and packaged locally; (c) import of a bulk, finished product (tablets or capsules) that is packaged and branded; and (d) or import of a branded packaged product...
December 26, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29261246/impact-of-statin-guidelines-on-statin-utilization-and-costs-in-an-employer-based-primary-care-clinic
#8
Holly E Gurgle, Marisa B Schauerhamer, Simón A Rodriguez, Carrie McAdam-Marx
OBJECTIVES: The purpose of this study was to describe statin utilization and costs in an employer-based patient cohort by comparing actual practice and assumed adoption of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) or 2016 US Preventive Services Task Force (USPSTF) statin recommendations versus the guidelines described in 2001 (and supplemented in 2004) in the Third Report of the National Cholesterol Education Program's Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (ATPIII)...
December 1, 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29241468/-addendum-to-the-dutch-guideline-for-minor-head-brain-injury
#9
C L van den Brand, J van der Naalt, G Hageman, H P Bienfait, R A van der Kruijk, K Jellema
- After introduction of the Dutch guideline for 'Care for patients with minor head/brain injury' (LTH guideline) in 2010, the number of CT scans has increased. Some of these scans were for patients with only trivial trauma and may not have been necessary.- In addition, since this guideline was implemented, there have been changes in the use of anticoagulants and platelet aggregation inhibitors. Non-vitamin-K-dependent oral anticoagulants (NOACs) and platelet aggregation inhibitors, or combinations of these, are prescribed more often...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29236747/a-meta-analysis-of-effects-of-post-hatch-food-and-water-deprivation-on-development-performance-and-welfare-of-chickens
#10
Ingrid C de Jong, Johan van Riel, Marc B M Bracke, Henry van den Brand
A 'meta-analysis' was performed to determine effects of post-hatch food and water deprivation (PHFWD) on chicken development, performance and welfare (including health). Two types of meta-analysis were performed on peer-reviewed scientific publications: a quantitative 'meta-analysis' (MA) and a qualitative analysis (QA). Previously reported effects of PHFWD were quantified in the MA, for variables related to performance, mortality and relative yolk sac weight. The QA counted the number of studies reporting (non-)significant effects when five or more records were available in the data set (i...
2017: PloS One
https://www.readbyqxmd.com/read/29232439/body-mass-index-and-breast-cancer-survival-a-mendelian-randomization-analysis
#11
Qi Guo, Stephen Burgess, Constance Turman, Manjeet K Bolla, Qin Wang, Michael Lush, Jean Abraham, Kristiina Aittomäki, Irene L Andrulis, Carmel Apicella, Volker Arndt, Myrto Barrdahl, Javier Benitez, Christine D Berg, Carl Blomqvist, Stig E Bojesen, Bernardo Bonanni, Judith S Brand, Hermann Brenner, Annegien Broeks, Barbara Burwinkel, Carlos Caldas, Daniele Campa, Federico Canzian, Jenny Chang-Claude, Stephen J Chanock, Suet-Feung Chin, Fergus J Couch, Angela Cox, Simon S Cross, Cezary Cybulski, Kamila Czene, Hatef Darabi, Peter Devilee, W Ryan Diver, Alison M Dunning, Helena M Earl, Diana M Eccles, Arif B Ekici, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Dieter Flesch-Janys, Henrik Flyger, Susan M Gapstur, Mia M Gaudet, Graham G Giles, Gord Glendon, Mervi Grip, Jacek Gronwald, Lothar Haeberle, Christopher A Haiman, Per Hall, Ute Hamann, Susan Hankinson, Jaana M Hartikainen, Alexander Hein, Louise Hiller, Frans B Hogervorst, Bernd Holleczek, Maartje J Hooning, Robert N Hoover, Keith Humphreys, David J Hunter, Anika Hüsing, Anna Jakubowska, Arja Jukkola-Vuorinen, Rudolf Kaaks, Maria Kabisch, Vesa Kataja, Julia A Knight, Linetta B Koppert, Veli-Matti Kosma, Vessela N Kristensen, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Annika Lindblom, Sara Lindström, Jolanta Lissowska, Jan Lubinski, Mitchell J Machiela, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Federik Marme, John W M Martens, Catriona McLean, Primitiva Menéndez, Roger L Milne, Anna Marie Mulligan, Taru A Muranen, Heli Nevanlinna, Patrick Neven, Sune F Nielsen, Børge G Nordestgaard, Janet E Olson, Jose I A Perez, Paolo Peterlongo, Kelly-Anne Phillips, Christopher J Poole, Katri Pylkäs, Paolo Radice, Nazneen Rahman, Thomas Rüdiger, Anja Rudolph, Elinor J Sawyer, Fredrick Schumacher, Petra Seibold, Caroline Seynaeve, Mitul Shah, Ann Smeets, Melissa C Southey, Rob A E M Tollenaar, Ian Tomlinson, Helen Tsimiklis, Hans-Ulrich Ulmer, Celine Vachon, Ans M W van den Ouweland, Laura J Van't Veer, Hans Wildiers, Walter Willett, Robert Winqvist, M Pilar Zamora, Georgia Chenevix-Trench, Thilo Dörk, Douglas F Easton, Montserrat García-Closas, Peter Kraft, John L Hopper, Wei Zheng, Marjanka K Schmidt, Paul D P Pharoah
Background: There is increasing evidence that elevated body mass index (BMI) is associated with reduced survival for women with breast cancer. However, the underlying reasons remain unclear. We conducted a Mendelian randomization analysis to investigate a possible causal role of BMI in survival from breast cancer. Methods: We used individual-level data from six large breast cancer case-cohorts including a total of 36 210 individuals (2475 events) of European ancestry...
December 1, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29225710/novel-developments-in-the-pathogenesis-and-diagnosis-of-extranodal-marginal-zone-lymphoma
#12
REVIEW
Max I Schreuder, Michiel van den Brand, Konnie M Hebeda, Patricia J T A Groenen, J Han van Krieken, Blanca Scheijen
Extranodal marginal zone lymphoma (EMZL), mostly represented by mucosa-associated lymphoid tissue (MALT) type, also referred to as MALT lymphoma, is a clinically heterogeneous entity within the group of low-grade B cell lymphomas that arises in a wide range of different extranodal sites, including the stomach, lung, ocular adnexa, and skin. It represents the third most common non-Hodgkin lymphoma in the Western world, and the median age of occurrence is around 60 years. One characteristic aspect in a subset of EMZL detectable in about 25% of the cases is the presence of specific chromosomal translocations involving the genes MALT1 and BCL10, which lead to activation of the NF-κB signaling pathway...
December 2017: Journal of Hematopathology
https://www.readbyqxmd.com/read/29222108/illicit-cigarette-sales-in-indian-cities-findings-from-a-retail-survey
#13
Rijo M John, Hana Ross
OBJECTIVE: To estimate illicit cigarette consumption in India using a modified and replicable method and compare it with estimates generated by the tobacco industry and by a commercial entity. METHODS: The study employed a modified approach to cigarette pack analysis suitable for countries with prevalent single-cigarette sales. Empty cigarette packs generated by 1 day's single-cigarette sales were collected directly from cigarette vendors in four large and four small cities covering the length and breadth of India...
December 8, 2017: Tobacco Control
https://www.readbyqxmd.com/read/29221587/histoire-du-thermal%C3%A3-sme-%C3%A3-av%C3%A3-ne-les-bains-et-gen%C3%A3-se-de-l%C3%A2-eau-thermale-d%C3%A2-av%C3%A3-ne-history-of-thermalism-at-av%C3%A3-ne-les-bains-and-genesis-of-the-av%C3%A3-ne-thermal-spring-water
#14
B Selas
Avene thermal spring water is recognized for more than two centuries for its benefits on skin diseases. Since 1975, the Pierre Fabre Group has modernized the facilities, and developed the brand « Eau Thermal Avène », allowing more than 2,500 patients/year to be treated by this therapeutic water. The regulation requires high standards on origin, bacteriological purity and physico-chemical stability. Many works have allowed us to understand its origin, its underground path and identify its specific physico-chemical profile...
January 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29220876/pharmacokinetics-clot-strength-and-safety-of-a-new-fibrinogen-concentrate-randomized-comparison-with-active-control-in-congenital-fibrinogen-deficiency
#15
C Ross, S Rangarajan, M Karimi, G H Toogeh, S Apte, T Lissitchkov, S Acharya, M J Manco-Johnson, A Srivastava, B Brand, B Schwartz, S Knaub, F Peyvandi
BACKGROUND: Human fibrinogen concentrate (HFC) corrects fibrinogen deficiency in congenital a-/hypofibrinogenaemia. OBJECTIVES: To assess pharmacokinetics (PK), effects on thromboelastometry maximum clot firmness (MCF), and safety of a new double virus-inactivated/eliminated, highly purified HFC vs. active control. PATIENTS/METHODS: In this multinational, randomized, phase II, open-label, crossover study in 22 congenital afibrinogenaemia patients ≥12 years, 70 mg kg-1 of new HFC (FIBRYGA, Octapharma AG) or control (Haemocomplettan® P/RiaSTAP™ , CSL Behring GmbH) were administered, followed by crossover to the other concentrate...
December 8, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29212052/biotic-diversity-of-benthic-macroinvertebrates-at-contrasting-glacier-fed-systems-in-patagonia-mountains-the-role-of-environmental-heterogeneity-facing-global-warming
#16
María Laura Miserendino, Cecilia Brand, Luis B Epele, Cecilia Y Di Prinzio, Guillermo H Omad, Miguel Archangelsky, Oscar Martínez, Adriana M Kutschker
Patagonia is by far the largest glacierized area in South America. However, little is known about ecology, functioning and biodiversity of glacier-fed streams facing global warming. We investigated changes in environmental features and macroinvertebrate communities along a longitudinal gradient of glacier influence of two Patagonian systems that differ in glacier cover magnitude and the spatial sequence of lotic and lentic phases. Both glaciers, Torrecillas (~5.5km2, Torrecillas system) and Cónico (~0.44km2, Baggilt system), are retreating...
December 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29208078/community-junior-sport-sponsorship-an-online-experiment-assessing-children-s-responses-to-unhealthy-food-v-pro-health-sponsorship-options
#17
Helen Dixon, Maree Scully, Melanie Wakefield, Bridget Kelly, Simone Pettigrew
OBJECTIVE: To explore children's responses to sponsorship of community junior sport by unhealthy food brands and investigate the utility of alternative, pro-health sponsorship options. DESIGN: Between-subjects experiment, with four sponsorship conditions: A, non-food branding (control); B, unhealthy food branding; C, healthier food branding; D, obesity prevention campaign branding. SETTING: Online experiment conducted in schools. Participants were shown a junior sports pack for their favourite sport that contained merchandise with branding representing their assigned sponsorship condition...
December 6, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29186993/medication-use-in-adults-with-attention-deficit-hyperactivity-disorder-in-a-commercially-insured-population-in-the-united-states
#18
Zhou Zhou, Zheng-Yi Zhou, Sneha S Kelkar, Vanja Sikirica, Jipan Xie, Regina Grebla
OBJECTIVE: To examine real-world prescription medication usage among commercially-insured adults with attention deficit/hyperactivity disorder (ADHD) in the US. METHODS: Adults with ADHD who received ≥1 ADHD medication during 2013 were identified from a large US claims database. Combination therapy was defined as an overlap of ≥30 days between the index (first treatment ≥30 days in 2013) and another medication(s). Patients were classified into six groups: long-acting (LA) monotherapy, short-acting (SA) monotherapy, LA + LA, SA + SA, LA + SA, and >2 therapies...
December 8, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29182629/effects-of-peroxisome-proliferator-activated-receptors-ppar-%C3%AE-and-%C3%AE-agonists-on-cochlear-protection-from-oxidative-stress
#19
Marijana Sekulic-Jablanovic, Vesna Petkovic, Matthew B Wright, Krystsina Kucharava, Nathan Huerzeler, Soledad Levano, Yves Brand, Katharina Leitmeyer, Andrea Glutz, Alexander Bausch, Daniel Bodmer
Various insults cause ototoxicity in mammals by increasing oxidative stress leading to apoptosis of auditory hair cells (HCs). The thiazolidinediones (TZDs; e.g., pioglitazone) and fibrate (e.g., fenofibrate) drugs are used for the treatment of diabetes and dyslipidemia. These agents target the peroxisome proliferator-activated receptors, PPARγ and PPARα, which are transcription factors that influence glucose and lipid metabolism, inflammation, and organ protection. In this study, we explored the effects of pioglitazone and other PPAR agonists to prevent gentamicin-induced oxidative stress and apoptosis in mouse organ of Corti (OC) explants...
2017: PloS One
https://www.readbyqxmd.com/read/29178960/the-impact-of-a-physician-detailing-and-sampling-program-for-generic-atorvastatin-an-interrupted-time-series-analysis
#20
Heather C Worthington, Lucy Cheng, Sumit R Majumdar, Steven G Morgan, Colette B Raymond, Stephen B Soumerai, Michael R Law
BACKGROUND: In 2011, Manitoba implemented a province-wide program of physician detailing and free sampling for generic atorvastatin to increase use of this generic statin. We examined the impact of this unique combined program of detailing and sampling for generic atorvastatin on the use and cost of statin medicines, market share of generic atorvastatin, the choice of starting statin for new users, and switching from a branded statin to generic atorvastatin. METHODS: We conducted a retrospective study of Manitoba insurance claims data for all continuously enrolled patients who filled one or more prescriptions for a statin between 2008 and 2013...
November 25, 2017: Implementation Science: IS
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