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Shannon B Spencer, Shigang Wang, Karl Woitas, Kristen Glass, Allen R Kunselman, Akif Ündar
The objective of this study was to evaluate an alternative neonatal extracorporeal life support (ECLS) circuit with a RotaFlow centrifugal pump and Better-Bladder (BB) for hemodynamic performance and gaseous microemboli (GME) capture in a simulated neonatal ECLS system. The circuit consisted of a Maquet RotaFlow centrifugal pump, a Quadrox-iD Pediatric diffusion membrane oxygenator, 8 Fr arterial cannula, and 10 Fr venous cannula. A "Y" connector was inserted into the venous line to allow for comparison between BB and no BB...
October 13, 2016: Artificial Organs
Matthew Schuldes, Jeffrey B Riley, Stephen G Francis, Sean Clingan
Gaseous microemboli (GME) are an abnormal physiological occurrence during cardiopulmonary bypass and extracorporeal membrane oxygenation (ECMO). Several studies have correlated negative sequelae with exposure to increased amounts of GME. Hypobaric oxygenation is effective at eliminating GME in hollow-fiber microporous membrane oxygenators. However, hollow-fiber diffusion membrane oxygenators, which are commonly used for ECMO, have yet to be validated. The purpose of this study was to determine if hypobaric oxygenation, compared against normobaric oxygenation, can reduce introduced GME when used on diffusion membrane oxygenators...
September 2016: Journal of Extra-corporeal Technology
Alisa Nagler, Deborah L Engle, Mariah Rudd, Saumil M Chudgar, John L Weinerth, Catherine M Kuhn, Edward Buckley, Colleen O'Connor Grochowski
BACKGROUND: There is a paucity of information regarding institutional targets for the number of undergraduate medical education (UME) graduates being matched to graduate medical education (GME) programs at their home institutions. At our institution, the Duke University, the number of UME graduates matched to GME programs declined dramatically in 2011. To better understand why this decline may have happened, we sought to identify perceived quality metrics for UME and GME learners, evaluate trends in match outcomes and educational program characteristics, and explore whether there is an ideal retention rate for UME graduates in their home institutions' GME programs...
2016: Medical Education Online
Jonathan S Abelson, Genevieve Chartrand, Tracy-Ann Moo, Maureen Moore, Heather Yeo
BACKGROUND: There have been many efforts to increase the number of women surgeons. We provide an update of women surgeon representation along the pathway to surgical academia. METHODS: Data was extracted from Association of American Medical Colleges FACTS and Faculty Administrative Management Online User System as well as GME annual reports starting in 1994 until the last year available for each. RESULTS: The proportion of graduating women medical students has increased on average ...
October 2016: American Journal of Surgery
Tayfun Özçelik, Onur Emre Onat
Study of the Greater Middle East (GME), home to approximately 10% of the world's population, has made invaluable contributions to the characterization of rare genetic disease, especially recessive conditions arising from the tradition of consanguinity and large families with multiple children. A new study now reports 1,111 unrelated exomes from the GME and provides a comprehensive view of genetic variation for enhanced discovery of disease-associated genes.
August 30, 2016: Nature Genetics
D K Gessner, M Bonarius, E Most, A Fiesel, K Eder
Recent studies have shown that supplementation of plant products rich in polyphenols exerts anti-inflammatory effects in the small intestine and improves feed conversion in piglets. This study aimed to investigate whether dietary polyphenols have also anti-inflammatory and cytoprotective effects in the liver of piglets. For this end, relative mRNA concentrations of eight genes involved in proinflammatory pathways, eight genes involved in the antioxidative and cytoprotective system, six genes of phase I and phase II metabolism and 15 genes of the unfolded protein response (triggered by stress of the endoplasmic reticulum) in the liver of pigs fed diets supplemented with either 1% of grape seed and grape marc meal extract (GME) or 1% spent hops (SH) as sources of polyphenols were determined...
August 26, 2016: Journal of Animal Physiology and Animal Nutrition
(no author information available yet)
We are revising the Medicare hospital inpatient prospective payment systems (IPPS) for operating and capital-related costs of acute care hospitals to implement changes arising from our continuing experience with these systems for FY 2017. Some of these changes will implement certain statutory provisions contained in the Pathway for Sustainable Growth Reform Act of 2013, the Improving Medicare Post-Acute Care Transformation Act of 2014, the Notice of Observation Treatment and Implications for Care Eligibility Act of 2015, and other legislation...
August 22, 2016: Federal Register
Grant S Hoekzema, Lisa Maxwell, Joseph W Gravel, Walter W Mills, William Geiger, J David Honeycutt
BACKGROUND: In 2013, the World Organisation of Family Doctors published training standards for post-graduate medical education (GME) in Family Medicine/General Practice (FP/GP). GME quality has not been well-defined, other than meeting accreditation standards. In 2009, the Association of Family Medicine Residency Directors (AFMRD) developed a tool that would aid in raising the quality of family medicine residency training in the USA. OBJECTIVE: We describe the development of this quality improvement tool, which we called the residency performance index (RPI), and its first three years of use by US family medicine residency (FMR) programmes...
September 2016: Education for Primary Care
Amy Lynn Sorrel
Thanks to years of TMA advocacy, the 2015 legislature more than tripled 2013 graduate medical education monies under an expansion initiative to help secure a pathway for doctors-in-training to enter the workforce.
2016: Texas Medicine
Marco C Stehouwer, Kristina R Legg, Roel de Vroege, Johannes C Kelder, Erik Hofman, Bastian A de Mol, Peter Bruins
Gaseous microemboli (GME) may originate from the extracorporeal circuit and enter the arterial circulation of the patient. GME are thought to contribute to cerebral deficit and to adverse outcome after cardiac surgery. The arterial filter is a specially designed component for removing both gaseous and solid microemboli. Integration of an arterial filter with an oxygenator is a contemporary concept, reducing both prime volume and foreign surface area. This study aims to determine the air-handling properties of four contemporary oxygenator devices with an integrated arterial filter...
August 11, 2016: Perfusion
Ann E Van Heest, Felicity Fishman, Julie Agel
BACKGROUND: This study was undertaken to update our report from academic years 2004-2005 through 2008-2009, to include 5 additional years of the Association of American Medical Colleges GME Track data. This study will test the hypothesis that, when compared with the data from 2004-2005 through 2008-2009, there were no substantial changes from 2009-2010 through 2013-2014 in the distribution of orthopaedic surgery residency programs that train female residents and have been accredited by the Accreditation Council for Graduate Medical Education (ACGME)...
August 3, 2016: Journal of Bone and Joint Surgery. American Volume
Esther H Chen, Hemal K Kanzaria, Kaoru Itakura, Juanita Booker-Vaughns, Kabir Yadav, Bryan G Kane
Shared Decision Making (SDM) is a patient-centered communication skill that is essential for all physicians to provide quality care. Like any competency or procedural skill, it can and should be introduced to medical students during their clerkships (Undergraduate Medical Education or UME), taught and assessed during residency training (Graduate Medical Education or GME), and have documentation of maintenance throughout an emergency physician's career (denoted as Continuing Medical Education or CME). A subgroup representing academic Emergency Medicine (EM) faculty, residents, content experts, and patients convened at the 2016 Academic Emergency Medicine Consensus Conference on Shared Decision Making to develop a research agenda toward improving implementation of SDM through sustainable education efforts...
July 21, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Eric M Scott, Anason Halees, Yuval Itan, Emily G Spencer, Yupeng He, Mostafa Abdellateef Azab, Stacey B Gabriel, Aziz Belkadi, Bertrand Boisson, Laurent Abel, Andrew G Clark, Fowzan S Alkuraya, Jean-Laurent Casanova, Joseph G Gleeson
The Greater Middle East (GME) has been a central hub of human migration and population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf region, North Africa, and Central Asia, has resulted in an elevated burden of recessive disease. Here we generated a whole-exome GME variome from 1,111 unrelated subjects. We detected substantial diversity and admixture in continental and subregional populations, corresponding to several ancient founder populations with little evidence of bottlenecks...
September 2016: Nature Genetics
Linda A Liang, Alisa Weber, Caroline Herr, Lana Hendrowarsito, Nicole Meyer, Gabriele Bolte, Uta Nennstiel-Ratzel, Stefanie Kolb
BACKGROUND: The federal state of Bavaria, Germany enforced a comprehensive smoking ban across all enclosed public areas in 2008 to protect non-smokers from second-hand smoke (SHS). Evidence against displacement of smoking to homes is abundant, however long-term assessments are few. We aim to report prevalence of children's SHS exposure before and after the ban, parental smoking behaviour and exposure risk factors. METHODS: Cross-sectional data of children aged 5-6 years old in Bavaria (n = 22 944) were collected in 2004/5 and 2005/6 (S1 and S2) before the ban and after in 2008/9 and 2012/13 (S4 and S6)...
July 14, 2016: European Journal of Public Health
Mark W Puls
No abstract text is available yet for this article.
June 2016: Bulletin of the American College of Surgeons
Toshihiko Oka, Noboru Ohta
We report a method to produce two different monodomains of an inverse hexagonal II (HII) phase in capillaries. Capillaries filled with glyceryl monooleyl ether (GME) in an inverted micellar phase were soaked in water. After a week, a monodomain of the HII phase with straight cylinders was observed in a capillary with a diameter of 1.0 mm. The axis of the straight cylinders was almost parallel to the capillary axis, and the cylinders were slightly undulated. The lattice constant of the HII phase was 5.85 nm, which indicated the monodomain was fully hydrated...
August 2, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
R Carter Clement, Erik Olsson, Prateek Katti, Robert J Esther
BACKGROUND: Residency programs compete to attract applicants based on numerous factors. Previous research has suggested that medical students consider quality of life among the most important factors in selecting a program. One aspect of workplace quality of life is the cadre of non-monetary benefits offered to employees. However, with federal funding for graduate medical education (GME) under consideration for spending cuts, the source and continuation of such benefits may be in question...
July 2016: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
Louise Mounet-Gilbert, Marie Dumont, Carine Ferrand, Céline Bournonville, Antoine Monier, Joana Jorly, Martine Lemaire-Chamley, Kentaro Mori, Isabelle Atienza, Michel Hernould, Rebecca Stevens, Arnaud Lehner, Jean Claude Mollet, Christophe Rothan, Patrice Lerouge, Pierre Baldet
GDP-D-mannose epimerase (GME, EC converts GDP-D-mannose to GDP-L-galactose, and is considered to be a central enzyme connecting the major ascorbate biosynthesis pathway to primary cell wall metabolism in higher plants. Our previous work demonstrated that GME is crucial for both ascorbate and cell wall biosynthesis in tomato. The aim of the present study was to investigate the respective role in ascorbate and cell wall biosynthesis of the two SlGME genes present in tomato by targeting each of them through an RNAi-silencing approach...
August 2016: Journal of Experimental Botany
Marsha Regenstein, Kiki Nocella, Mariellen Malloy Jewers, Fitzhugh Mullan
Policymakers have long been concerned about the adequacy of the U.S. primary care workforce, especially in rural and low-income areas. In an effort to respond to increased demand for primary care services from new private health insurance markets and Medicaid coverage expansions under the..
August 18, 2016: New England Journal of Medicine
Daniel G Tobin, Benjamin R Doolittle, Matthew S Ellman, Christopher B Ruser, Rebecca S Brienza, Inginia Genao
Teaching residents to practice independently is a core objective of graduate medical education (GME). However, billing rules established by the Centers for Medicare and Medicaid Services (CMS) require that teaching physicians physically be present in the examination room for the care they bill, unless the training program qualifies for the Primary Care Exception Rule (PCER). Teaching physicians in programs that use this exception can bill for indirectly supervised ambulatory care once the resident who provides that care has completed six months of training...
June 28, 2016: Academic Medicine: Journal of the Association of American Medical Colleges
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