Jianlin Cai, Ying Liu, Cheng Qian, Yixuan Gao, Sheng Zhao, Yingwei Ma, Xingyu Xiang, Jing Xu, Feng Zhang, Maozhong Li, Hongmei Xu, Qi Li, Chongyang Li, Yitong Lin, Baicheng Xia, Aili Cui, Yan Zhang, Zhen Zhu, Naiying Mao
Human adenovirus (HAdV) is a significant viral pathogen causing severe acute respiratory infections (SARIs) in children. To improve the understanding of type distribution and viral genetic characterization of HAdV in severe cases, this study enrolled 3404 pediatric SARI cases from eight provinces of China spanning 2017-2021, resulting in the acquisition of 112 HAdV strains. HAdV-type identification, based on three target genes (penton base, hexon, and fiber), confirmed the diversity of HAdV types in SARI cases...
April 2024: Journal of Medical Virology