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https://www.readbyqxmd.com/read/29275928/spontaneous-coronary-artery-dissection-scad-the-underdiagnosed-cardiac-condition-that-plagues-women
#1
REVIEW
Sandrine Lebrun, Rachel M Bond
Coronary heart disease (CHD) continues to be understudied, underdiagnosed, and undertreated in women. Gender and age bias complicate the evaluation of women with acute coronary syndrome (ACS). As a result, conditions like spontaneous coronary artery dissection (SCAD) are often missed. SCAD is an infrequent yet important cause of myocardial infarction (MI) with a predilection for young to middle aged women. The condition is thought to be under-reported, likely a result of both low index of suspicion as well as an unfamiliarity with SCAD's angiographic variants...
December 11, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29246884/mortality-of-myocardial-infarction-by-sex-age-and-obstructive-coronary-artery-disease-status-in-the-action-registry-gwtg-acute-coronary-treatment-and-intervention-outcomes-network-registry-get-with-the-guidelines
#2
Nathaniel R Smilowitz, Asha M Mahajan, Matthew T Roe, Anne S Hellkamp, Karen Chiswell, Martha Gulati, Harmony R Reynolds
BACKGROUND: Sex differences in early mortality after myocardial infarction (MI) vary by age. MI with nonobstructive coronary arteries (MINOCA [<50% stenosis]) is more common among younger patients and women, and MINOCA has a better prognosis than MI with obstructive coronary artery disease (MI-CAD). The relationship between age, sex, and obstructive CAD status and outcomes post-MI has not been established. METHODS AND RESULTS: Adults who underwent coronary angiography for acute ST-segment-elevation and non-ST-segment-elevation MI in the National Cardiovascular Data Registry ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines) from 2007 to 2014 were identified...
December 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29240964/psycho-emotional-disorders-as-incoming-risk-factors-for-myocardial-infarction-with-non-obstructive-coronary-arteries
#3
Javier López-Pais, Bárbara Izquierdo Coronel, David Galán Gil, María Jesús Espinosa Pascual, Carlos Gustavo Martinez Peredo, Paula Awamleh García, Juan Górriz Magaña, Rebeca Mata Caballero, Alfonso Fraile Sanz, Javier Muñiz, Joaquín J Alonso Martín
BACKGROUND: There is an emerging field underlying the myocardial infarction with non-obstructive coronary arteries (MINOCA). The aim of this study was to evaluate the impact of psycho-emotional disorders and social habits in MINOCA patients. METHODS: The study included 95 consecutive patients diagnosed of MINOCA and 178 patients with myocardial infarction (MI) and obstructive lesions. MINOCA patients were included when they fulfilled the three main criteria: Accomplishment of the Third Universal Definition of Myocardial Infarction, absence of obstructive coronary arteries and no clinically overt specific cause for the acute presentation...
December 14, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29228159/patients-with-acute-myocardial-infarction-and-non-obstructive-coronary-arteries-safety-and-prognostic-relevance-of-invasive-coronary-provocative-tests
#4
Rocco A Montone, Giampaolo Niccoli, Francesco Fracassi, Michele Russo, Filippo Gurgoglione, Giulia Cammà, Gaetano A Lanza, Filippo Crea
Aims: Functional alterations of epicardial coronary arteries or coronary microcirculation represent a frequent cause of myocardial infarction and non-obstructive coronary arteries (MINOCA). We aimed at assessing the prognostic value of intracoronary provocative tests in patients presenting with MINOCA and in which other causes of MINOCA have been excluded. Methods and results: We prospectively evaluated patients with a diagnosis of MINOCA, excluding patients with aetiologies other than suspected coronary vasomotor abnormalities...
January 7, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29119223/-acute-myocardial-infarction-in-patients-with-st-segment-elevation-myocardial-infarction-esc-guidelines-2017
#5
REVIEW
H Thiele, S Desch, S de Waha
This article gives an update on the management of acute ST-segment elevation myocardial infarction (STEMI) according to the recently released European Society of Cardiology guidelines 2017 and the modifications are compared to the previous STEMI guidelines from 2012. Primary percutaneous coronary intervention (PCI) remains the preferred reperfusion strategy. New guideline recommendations relate to the access site with a clear preference for the radial artery, use of drug-eluting stents over bare metal stents, complete revascularization during the index hospitalization, and avoidance of routine thrombus aspiration...
December 2017: Herz
https://www.readbyqxmd.com/read/28738781/the-value-of-a-new-cardiac-magnetic-resonance-imaging-protocol-in-myocardial-infarction-with-non-obstructive-coronary-arteries-minoca-a-case-control-study-using-historical-controls-from-a-previous-study-with-similar-inclusion-criteria
#6
Per Tornvall, E B Brolin, K Caidahl, K Cederlund, O Collste, M Daniel, C Ekenbäck, J Jensen, S Y-Hassan, L Henareh, C Hofman-Bang, P Lyngå, E Maret, N Sarkar, J Spaak, M Sundqvist, P Sörensson, M Ugander, S Agewall
BACKGROUND: Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) is common with a prevalence of 6% of all patients fulfilling the diagnosis of myocardial infarction. MINOCA should be considered a working diagnosis. Cardiac Magnetic Resonance (CMR) imaging has recently been suggested to be of great value to determine the cause behind MINOCA. The objectives of this paper are to describe the rationale behind the second Stockholm Myocardial Infarction with Normal Coronaries (SMINC-2) study and to discuss the protocol for investigation of MINOCA patients in the light of the recently published position paper from the European Society of Cardiology...
July 24, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28610801/effect-of-myocardial-infarction-with-nonobstructive-coronary-arteries-on-physical-capacity-and-quality-of-life
#7
MULTICENTER STUDY
Maria Daniel, Stefan Agewall, Kenneth Caidahl, Olov Collste, Christina Ekenbäck, Mats Frick, Shams Y-Hassan, Logman Henareh, Tomas Jernberg, Karin Malmqvist, Karin Schenck-Gustafsson, Peder Sörensson, Örjan Sundin, Claes Hofman-Bang, Per Tornvall
Patients with myocardial infarction with nonobstructive coronary arteries (MINOCA), including Takotsubo syndrome (TS), are considered to have a better survival compared with those with coronary heart disease (CHD). Studies of patients with MINOCA measuring physical and mental function including matched control groups are lacking. The aim of this study was to determine the physical capacity and quality of life in patients with MINOCA. One-hundred patients with MINOCA along with TS (25%) were investigated from 2007 to 2011...
August 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28416521/myocardial-infarction-with-nonobstructive-coronary-arteries-minoca-the-past-present-and-future-management
#8
EDITORIAL
Sivabaskari Pasupathy, Rosanna Tavella, John F Beltrame
No abstract text is available yet for this article.
April 18, 2017: Circulation
https://www.readbyqxmd.com/read/28400924/risk-of-ventricular-arrhythmia-in-patients-with-myocardial-infarction-and-non-obstructive-coronary-arteries-and-normal-ejection-fraction
#9
Loïc Bière, Marjorie Niro, Hervé Pouliquen, Jean-Baptiste Gourraud, Fabrice Prunier, Alain Furber, Vincent Probst
AIM: To assess the arrhythmic determinants and prognosis of patients presenting with myocardial infarction and non-obstructive coronary arteries (MINOCA) with normal ejection fraction (EF). METHODS: This is an observational analysis of 131 MINOCA patients with normal EF. Three cardiac magnetic resonance (CMR) diagnosis classes were recognized according to the late gadolinium enhancement (LGE) pattern: Myocardial infarction (MI) (n = 34), myocarditis (n = 47), and "no LGE" (n = 50)...
March 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28179398/medical-therapy-for-secondary-prevention-and-long-term-outcome-in-patients-with-myocardial-infarction-with-nonobstructive-coronary-artery-disease
#10
Bertil Lindahl, Tomasz Baron, David Erlinge, Nermin Hadziosmanovic, Anna Nordenskjöld, Anton Gard, Tomas Jernberg
BACKGROUND: Myocardial infarction with nonobstructive coronary arteries (MINOCA) occurs in 5% to 10% of all patients with myocardial infarction. Clinical trials of secondary prevention treatment in MINOCA patients are lacking. Therefore, the aim of this study was to examine the associations between treatment with statins, renin-angiotensin system blockers, β-blockers, dual antiplatelet therapy, and long-term cardiovascular events. METHODS: This is an observational study of MINOCA patients recorded in the SWEDEHEART registry (the Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapy) between July 2003 and June 2013 and followed until December 2013 for outcome events in the Swedish Cause of Death Register and National Patient Register...
April 18, 2017: Circulation
https://www.readbyqxmd.com/read/27892770/myocardial-infarction-with-non-obstructive-coronary-arteries-minoca-a-whole-new-ball-game
#11
REVIEW
Nana Poku, Stephane Noble
MINOCA is a clinical syndrome that encompasses a subgroup of heterogeneous patients who present with myocardial infarction yet do not have any significant coronary artery obstruction on angiogram. As many as one in ten patients with acute myocardial infarction (AMI) will not have an occluded coronary artery, and the reported prevalence keeps rising, in part due to better recognition of this syndrome. Current guidelines offer several diagnostic algorithms but MINOCA remains largely under-recognised and little is known about whether patients might benefit from a more specific treatment modality...
January 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/27459149/stress-cardiac-mri-in-women-with-myocardial-infarction-and-nonobstructive-coronary-artery-disease
#12
Rina Mauricio, Monvadi B Srichai, Leon Axel, Judith S Hochman, Harmony R Reynolds
BACKGROUND: In a prospective study, cardiac MRI (CMR) and intravascular ultrasound were performed in women with myocardial infarction (MI) and nonobstructive coronary artery disease (MINOCA). Forty participants underwent adenosine-stress CMR (sCMR). HYPOTHESIS: Abnormal perfusion may co-localize with ischemic late gadolinium enhancement (LGE) and T2-weighted signal hyperintensity (T2+), suggesting microvascular dysfunction contributed to MI. METHODS: Qualitative perfusion analysis was performed by 2 independent readers...
October 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27390950/impact-of-aspirin-on-the-prognosis-in-patients-with-coronary-spasm-without-significant-atherosclerotic-stenosis
#13
Masanobu Ishii, Koichi Kaikita, Koji Sato, Kenshi Yamanaga, Takashi Miyazaki, Tomonori Akasaka, Noriaki Tabata, Yuichiro Arima, Daisuke Sueta, Kenji Sakamoto, Eiichiro Yamamoto, Kenichi Tsujita, Megumi Yamamuro, Sunao Kojima, Hirofumi Soejima, Seiji Hokimoto, Kunihiko Matsui, Hisao Ogawa
BACKGROUND: Coronary spasm is one of the mechanisms of myocardial infarction with nonobstructive coronary arteries (MINOCA). The aim of this study was to investigate the effects of aspirin on future cardiovascular events in patients with coronary vasospastic angina (VSA) with non-significant atherosclerotic stenosis. METHODS: This was the retrospective analysis of the 640 VSA patients with non-significant atherosclerotic stenosis (≤50% stenosis) among 1,877 consecutive patients who underwent acetylcholine (ACh)-provocation testing between January 1991 and December 2010...
October 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/26804291/optical-coherence-tomography-oct-evaluation-of-intermediate-coronary-lesions-in-patients-with-nstemi
#14
Nigussie Bogale, Mathieu Lempereur, Imran Sheikh, David Wood, Jacqueline Saw, Anthony Fung
INTRODUCTION: Coronary angiography is commonly performed following non-ST segment elevation myocardial infarction (NSTEMI) to assess the need for revascularization. Some of these patients have myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA). Patients without severe obstructive lesions are usually treated conservatively. However, coronary angiography has known limitations in the assessment of lesion severity. We report our experience of using coronary Optical Coherence Tomography (OCT) in a series of patients without severe obstructive coronary lesions...
March 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/26597354/the-what-when-who-why-how-and-where-of-myocardial-infarction-with-non-obstructive-coronary-arteries-minoca
#15
REVIEW
Sivabaskari Pasupathy, Rosanna Tavella, John F Beltrame
Myocardial infarction with non-obstructive coronary arteries (MINOCA) is an intriguing clinical entity that is being increasingly recognized with the more common use of coronary angiography during acute myocardial infarction. This review systematically addresses the contemporary understanding of MINOCA, including, (1) what are the diagnostic criteria, (2) when the diagnosis should be considered, (3) who is at risk, (4) why this new syndrome should be diagnosed, (5) how these patients should be managed, and (6) where to next?...
2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/26506121/prevalence-of-myocardial-bridging-in-patients-with-myocardial-infarction-and-nonobstructed-coronary-arteries
#16
Elin B Brolin, Torkel B Brismar, Olov Collste, Shams Y-Hassan, Loghman Henareh, Per Tornvall, Kerstin Cederlund
Mechanisms of acute myocardial infarction and nonobstructed coronary arteries (MINOCA) are incompletely understood. Myocardial bridging (MB) is usually considered a benign congenital variant, but serious complications have been reported. MB has also been proposed as a cause of takotsubo syndrome (TS). We aimed to examine whether MB was more frequent in patients with MINOCA or TS than in age- and gender-matched controls and to compare the MB detection rates of coronary computed tomography angiography (CTA) and invasive coronary angiography (ICA)...
December 15, 2015: American Journal of Cardiology
https://www.readbyqxmd.com/read/25967935/myocarditis-or-true-infarction-by-cardiac-magnetic-resonance-in-patients-with-a-clinical-diagnosis-of-myocardial-infarction-without-obstructive-coronary-disease-a-meta-analysis-of-individual-patient-data
#17
REVIEW
P Tornvall, E Gerbaud, A Behaghel, R Chopard, O Collste, E Laraudogoitia, G Leurent, N Meneveau, M Montaudon, E Perez-David, P Sörensson, S Agewall
OBJECTIVE: Myocardial Infarction with Non-Obstructed Coronary Arteries (MINOCA) is common, but the causes are to a large extent unknown. Thus, we aimed to study the prevalence of myocarditis and "true" myocardial infarction determined by cardiac magnetic resonance (CMR) imaging in MINOCA patients, and risk markers for these two conditions in this population. METHODS: A search was made in the PubMed and Cochrane databases using the search terms "Myocardial infarction", "Coronary angiography", "Normal coronary arteries" and "MRI"...
July 2015: Atherosclerosis
https://www.readbyqxmd.com/read/25587100/systematic-review-of-patients-presenting-with-suspected-myocardial-infarction-and-nonobstructive-coronary-arteries
#18
REVIEW
Sivabaskari Pasupathy, Tracy Air, Rachel P Dreyer, Rosanna Tavella, John F Beltrame
BACKGROUND: Myocardial infarction with nonobstructive coronary arteries (MINOCA) is a puzzling clinical entity with no previous evaluation of the literature. This systematic review aims to (1) quantify the prevalence, risk factors, and 12-month prognosis in patients with MINOCA, and (2) evaluate potential pathophysiological mechanisms underlying this disorder. METHODS AND RESULTS: Quantitative assessment of 28 publications using a meta-analytic approach evaluated the prevalence, clinical features, and prognosis of MINOCA...
March 10, 2015: Circulation
https://www.readbyqxmd.com/read/25526726/acute-myocardial-infarction-with-no-obstructive-coronary-atherosclerosis-mechanisms-and-management
#19
REVIEW
Giampaolo Niccoli, Giancarla Scalone, Filippo Crea
Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment...
February 21, 2015: European Heart Journal
https://www.readbyqxmd.com/read/22998397/assessing-patients-with-myocardial-infarction-and-nonobstructed-coronary-arteries-minoca
#20
EDITORIAL
John F Beltrame
No abstract text is available yet for this article.
February 2013: Journal of Internal Medicine
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