keyword
https://read.qxmd.com/read/38287256/assessment-of-bla-tem-bla-shv-and-bla-ctx-m-genes-of-antibiotic-resistance-in-gram-negative-bacilli-causing-urinary-tract-infections-in-khartoum-state-a-cross-sectional-study
#1
JOURNAL ARTICLE
Manal Ismail Abdalla Mohammedkheir, Elsheikh Mahgoub Gaafar, Eltayeb GareebAlla Eltayeb AbdAlla
BACKGROUND: Gram-negative bacilli are the most common etiological agents responsible for urinary tract infections. The prevalence of antibiotic resistance in Gram-negative bacilli is increasing at a rapid pace globally, which is constraining the available choices for UTI treatment. The objectives of this study are to identify the most common causal organisms of urinary tract infections (UTIs), and to determine their drug resistance patterns. MATERIALS AND METHODS: This was a cross-sectional hospital-based study conducted at El-Amal Hospital, Bahri Teaching Hospital, and Al-Baraha Hospital, Khartoum State, from March to October 2022...
January 29, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38144113/polyphenol-fingerprint-biological-activities-and-in-silico-studies-of-the-medicinal-plant-cistus-parviflorus-l-extract
#2
JOURNAL ARTICLE
Fatma A A El-Shibani, Ghassan M Sulaiman, Amr S Abouzied, Amer Al Ali, Abdulnaser Kh Abdulkarim, Abdullah D Alamami, Mohammed Asiri, Hamdoon A Mohammed
Cistus parviflorus L. (Cistaceae) is a medicinal plant with several folkloric applications, including being used for urinary tract infections and as a food additive. In this study, the polyphenolic diversity and the antioxidant, antidiabetic, and antimicrobial activities of the C. parviflorus methanolic extract were evaluated. Spectrophotometric and HPLC-based analyses using standard polyphenolic compounds were conducted to measure the phenolics and flavonoids in the plant extract. The in vitro DPPH, ORAC, FRAP, and α-glucosidase assays were used to evaluate the plant's antioxidant and antidiabetic activities...
December 19, 2023: ACS Omega
https://read.qxmd.com/read/38045632/frequency-of-urinary-tract-infection-among-patients-undergoing-implant-fixation-for-acute-trauma
#3
JOURNAL ARTICLE
Malik Amna Khatoon, Syed Muhammad Khalid Karim, Muhammad Wasim, Rufina Ali, Mariam Zaighum, Naveed Iqbal
OBJECTIVE: This study aims to determine the frequency of urinary tract infection (UTI), identify the isolated bacteria, and assess antibiotic sensitivity in patients undergoing orthopedic implant fixation for hip fractures. METHODOLOGY: After ethical approval from the institutional review board, this retrospective cross-sectional study was conducted at the Orthopedic Surgery Department of Dow University Hospital Karachi from June 2022 to June 2023. Through non-probability consecutive sampling, 186 patients above 16 years of age, of either gender, presenting with hip fractures such as intracapsular or extracapsular fractures, who underwent surgical fixation, were included in the study...
December 2023: Curēus
https://read.qxmd.com/read/37692408/antimicrobial-susceptibility-of-escherichia-coli-isolated-from-diabetic-patients-in-mogadishu-somalia
#4
JOURNAL ARTICLE
Shafie Abdulkadir Hassan, Yousif Mousa Alobaid Ahmed, Gallad Dahir Hassan
BACKGROUND: Urinary tract infections (UTIs) are a major concern for diabetic patients due to the impact of diabetes on the urinary tract and immune system. Escherichia coli is the most common pathogen causing UTIs in diabetic patients and is known for its resistance. This study aimed to assess the antimicrobial susceptibility of Escherichia coli strains isolated from diabetic patients in Mogadishu, Somalia. METHODS: This descriptive cross-sectional study was conducted at Ummah Hospital in Mogadishu, Somalia, from November 2021 to April 2022...
2023: Frontiers in Microbiology
https://read.qxmd.com/read/37599485/multi-drug-resistance-pattern-of-bacterial-isolates-from-urinary-tract-infection
#5
JOURNAL ARTICLE
- Faiza Asghar, - Sardar Muhammad, - Aftab Ahmad Anjum, - Tehreem Ali, - Abdul Shaheed Asghar, - Sobia Naureen, - Rabia Manzoor
In the community and among hospitalized patients, urinary tract infections (UTIs) rank as the most common bacterial infections. The researchers processed urine samples obtained from affiliated hospitals of Peshawar Medical College. The samples were examined under a microscope to assess the presence of bacteria, pus cells and red blood cells. Following this, the samples were inoculated on MacConkey and blood agar and subsequent antibiotic susceptibility testing was conducted. The findings revealed that 35.9% of hospitalized patients and 16...
July 2023: Pakistan Journal of Pharmaceutical Sciences
https://read.qxmd.com/read/37426467/profiling-of-antibiotic-resistance-among-uropathogens-isolated-from-patients-attending-kericho-county-referral-hospital
#6
JOURNAL ARTICLE
Gladys Chepkoech Mosonik, Janeth Jemutai Kombich
INTRODUCTION: urinary tract infection (UTI) comes second after respiratory infections in most communities and hospital settings, affecting people of all ages. Frequent use of antibiotics to manage UTI has resulted in development of resistance, calling upon policymakers to fast-track and enforce policies that guide the use of antibiotics in the country. This study intended to determine the current antibiotic resistance to uropathogens among patients attending Kericho County Referral Hospital...
2023: Pan African Medical Journal
https://read.qxmd.com/read/37303774/urinary-tract-infection-and-associated-factors-among-pregnant-women-receiving-antenatal-care-at-a-primary-health-care-facility-in-the-northern-region-of-ghana
#7
JOURNAL ARTICLE
Ezekiel K Vicar, Samuel E K Acquah, Williams Wallana, Eugene D Kuugbee, Emmanuel K Osbutey, Abigail Aidoo, Emmanuel Acheampong, Gloria Ivy Mensah
Urinary tract infection (UTI) is frequently encountered during pregnancy and is associated with adverse maternal, fetal, and neonatal effects. However, very little information is available on the prevalence of UTI among pregnant women in the northern part of Ghana, a region with a high birth rate. This study employed a cross-sectional analysis of the prevalence, antimicrobial profile, and risk factors associated with UTI in 560 pregnant women attending primary care for antenatal check-ups. Sociodemographic obstetrical history and personal hygiene information were obtained using a well-structured questionnaire...
2023: International Journal of Microbiology
https://read.qxmd.com/read/37257122/high-rates-of-esbl-producing-and-gentamycin-resistant-gram-negative-bacteria-during-the-first-week-of-life-a-multicenter-cross-sectional-study-among-infants-younger-than-2-months-with-urinary-tract-infection
#8
MULTICENTER STUDY
Muhammad Washahi, Dan Miron, Zohar Steinberg Ben Zeev, Gilad Chayen, Ron Jacob
INTRODUCTION: Reducing the risk of renal scarring in infants with urinary tract infection (UTI) necessitates timely and effective administration of antimicrobial treatment. The Israeli Medical Association recommends the empirical use of gentamicin and ampicillin for febrile infants younger than 2 months with suspected UTI. We aimed to assess the prevalence of Extended Spectrum Beta-Lactamase (ESBL)-producing and gentamicin-resistant Gram-negative UTI among infants younger than 2 months...
September 1, 2023: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/36803102/a-comparison-of-short-versus-long-course-intravenous-antibiotics-when-treating-urinary-tract-infection-in-infants-60-days-of-age
#9
JOURNAL ARTICLE
Fadi Zu'bi, Martha Pokarowski, Rusul Al-Kutbi, Michelle Science, Janaki Vallipuram, Fardod O'Kelly, Michael Chua, Jeremy Friedman, Martin Koyle
Urinary tract infections (UTIs) are a common reason for hospitalization in infants younger than 60 days, and the optimal approach to intravenous (IV) antibiotic therapy upon UTI diagnosis in this cohort is unknown. We determined whether there was an association between IV antibiotic therapy duration (long [>3 days] vs short [≤3 days]) and treatment failure via a retrospective review of infants with confirmed UTIs receiving IV antibiotics at a tertiary referral center. A total of 403 infants were included; 39% were treated with ampicillin and cefotaxime, and 34% with ampicillin and gentamycin or tobramycin...
February 21, 2023: Clinical Pediatrics
https://read.qxmd.com/read/36677505/susceptibility-and-virulence-of-enterobacteriaceae-isolated-from-urinary-tract-infections-in-benin
#10
JOURNAL ARTICLE
Funkè F Assouma, Haziz Sina, Tomabu Adjobimey, Agossou Damien Pacôme Noumavo, Akim Socohou, Bawa Boya, Ange D Dossou, Lauriane Akpovo, Basile Boni Saka Konmy, Jacques F Mavoungou, Adolphe Adjanohoun, Lamine Baba-Moussa
Enterobacteriaceae represent one of the main families of Gram-negative bacilli responsible for serious urinary tract infections (UTIs). The present study aimed to define the resistance profile and the virulence of Enterobacteriaceae strains isolated in urinary tract infections in Benin. A total of 390 urine samples were collected from patients with UTIs, and Enterobacteriaceae strains were isolated according to standard microbiology methods. The API 20E gallery was used for biochemical identification. All the isolated strains were subjected to antimicrobial susceptibility testing using the disc diffusion method...
January 14, 2023: Microorganisms
https://read.qxmd.com/read/36532664/cluster-analysis-and-geospatial-mapping-of-antibiotic-resistant-escherichia-coli-o157-in-southwest-nigerian-communities
#11
JOURNAL ARTICLE
Akinniyi Paul Akinduti, Oluwafunmilayo Ayodele, Babatunde Olanrewaju Motayo, Yemisi Dorcas Obafemi, Patrick Omoregie Isibor, Olubukola Wuraola Aboderin
Geospatial spread and antibiotic-resistant relatedness of Escherichia coli O157, which are important virulent serotypes causing severe complications leading to high intestinal morbidity and occasional mortality in several communities in southwest Nigeria, were evaluated. Biotyped Escherichia coli strains ( n  = 508) from subjects with diarrhea and related intestinal infections, various domestic water sources and food animal products were evaluated for antibiotic resistance relatedness, conjugative activity, virulence factor and biofilm production...
December 2022: One Health
https://read.qxmd.com/read/36310010/etiology-and-antibiotic-susceptibility-patterns-of-urinary-tract-infections-in-children-in-a-general-hospital-in-kuwait-a-5-year-retrospective-study
#12
JOURNAL ARTICLE
Khalifa Al Benwan, Wafaa Jamal
OBJECTIVE: The purpose was to determine the bacterial profile and prevalence of antibiotic resistance patterns of uropathogens, as well as evaluate the problem with extended-spectrum β-lactamases (ESBLs) producing isolates, causing urinary tract infections (UTIs) in children in Al-Amiri Hospital, Kuwait, over a 5-year period. MATERIALS AND METHODS: Significant isolates from symptomatic pediatric patients with UTIs from January 2017 to December 2021 were identified by conventional methods and the VITEK 2 identification card system...
October 29, 2022: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/36016776/bacterial-profile-and-antibiotic-susceptibility-pattern-of-uropathogens-causing-urinary-tract-infection-in-the-eastern-part-of-northern-india
#13
JOURNAL ARTICLE
Kanika Bhargava, Gopal Nath, Amit Bhargava, Ritu Kumari, G K Aseri, Neelam Jain
Urinary tract infection (UTI) is a common infectious disease that affects men and women. It is a significant health concern due to multidrug-resistant (MDR) organisms. Therefore, it is necessary to have a current understanding of the antibiotic susceptibility (AS) pattern of uropathogens to manage UTI effectively. Since the bacterial pathogen causing UTI and its AS vary with time and place, the prevailing AS pattern of the causative agents are essential for empirical antibiotic therapy. This study aims to determine the prevalence and AS of uropathogens isolated from UTI patients in the eastern part of Northern India...
2022: Frontiers in Microbiology
https://read.qxmd.com/read/34767605/bacterial-uropathogens-and-burden-of-antimicrobial-resistance-pattern-in-urine-specimens-referred-to-ethiopian-public-health-institute
#14
JOURNAL ARTICLE
Tesfa Addis, Yonas Mekonnen, Zeleke Ayenew, Surafel Fentaw, Habtamu Biazin
BACKGROUND: Urinary tract infections (UTIs) are the leading causes of morbidity in the general population, and is the second most common infectious disease after respiratory infections. Appropriate antibiotic therapy is essential to achieving good therapeutic results. Therefore, the purpose of this study was to investigate the profile of pathogens cultured from urinary tract infections and to determine their resistance profiles to commonly prescribed antibiotics. METHOD: A cross-sectional study was carried out at the National Referral Laboratory of the Ethiopian Institute of Public Health from January 2017 to December 2018...
2021: PloS One
https://read.qxmd.com/read/34607572/prevalence-antimicrobial-susceptibility-pattern-and-associated-risk-factors-for-urinary-tract-infections-in-pregnant-women-attending-anc-in-some-integrated-health-centers-in-the-buea-health-district
#15
JOURNAL ARTICLE
Innocentia Nji Ngong, Jerome Fru-Cho, Melduine Akom Yung, Jane-Francis Kihla Tatah Akoachere
BACKGROUND: Urinary tract infections (UTIs) are the second most frequent infections after respiratory tract infections that affect humans, with over 150 million cases per year. The anatomy of the female urinary tract predisposes them to UTIs than men. More so, physiological and hormonal changes during pregnancy put pregnant woman at risk of UTIs. Untreated UTI(s) in pregnancy can be detrimental to both the mother and child causing preterm labour, low birth weight and pyelonephritis. The situation is worrisome because the infection can be asymptomatic...
October 4, 2021: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/34333491/prolapse-surgery-what-kind-of-antibiotic-prophylaxis-is-necessary
#16
JOURNAL ARTICLE
Ester Illiano, Francesco Trama, Felice Crocetto, Gianluigi Califano, Achille Aveta, Gloria Motta, Antonio Luigi Pastore, Stefano Brancorsini, Consuelo Fabi, Elisabetta Costantini
INTRODUCTION: The aim of this study was to assess whether antibiotic prophylaxis or therapy is sufficient for laparoscopic or vaginal prolapse surgery with mesh. METHODS: This is a single-center prospective study. The study was divided into 3 groups. Protocol A: metronidazole (15 mg/kg) and piperacillin-tazobactam (2 g) 1 h before surgery and, for postoperative treatment, gentamycin (160 mg) 1 h before surgery in a single dose. Metronidazole and piperacillin-tazobactam were administered until hospital discharge...
July 30, 2021: Urologia Internationalis
https://read.qxmd.com/read/34321002/role-of-crispr-cas-system-on-antibiotic-resistance-patterns-of-enterococcus-faecalis
#17
JOURNAL ARTICLE
Pourya Gholizadeh, Mohammad Aghazadeh, Reza Ghotaslou, Mohammad Ahangarzadeh Rezaee, Tahereh Pirzadeh, Longzhu Cui, Shinya Watanabe, Hadi Feizi, Hiva Kadkhoda, Hossein Samadi Kafil
Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are one of the factors which can contribute to limiting the development and evolution of antibiotic resistance in bacteria. There are three genomic loci of CRISPR-Cas in Enterococcus faecalis. In this study, we aimed to assess correlation of the CRISPR-Cas system distribution with the acquisition of antibiotic resistance among E. faecalis isolates. A total of 151 isolates of E. faecalis were collected from urinary tract infections (UTI) and dental-root canal (DRC)...
July 28, 2021: Annals of Clinical Microbiology and Antimicrobials
https://read.qxmd.com/read/34161207/antimicrobial-resistance-in-bacteria-causing-urinary-tract-infections
#18
JOURNAL ARTICLE
Khonaw Kader Salh
BACKGROUND: Bacteria Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) are the main causes of Urinary Tract Infections (UTIs). This research aims to investigate the isolation of etiologic agents from patients with UTIs. In addition, it tries to investigate the incidence of ESBL genes in an etiologic agent. METHODS: This study included 1,000 positive growth isolates. Accordingly, the predominant pathogens associated with urinary tract infections, i...
June 22, 2021: Combinatorial Chemistry & High Throughput Screening
https://read.qxmd.com/read/33911886/prevalence-of-multidrug-resistant-uti-among-people-living-with-hiv-in-northern-tanzania
#19
JOURNAL ARTICLE
Bartholomeo Nicholaus Ngowi, Bruno Sunguya, Ayesiga Herman, Alfred Chacha, Eusebious Maro, Leonard France Rugarabamu, John Bartlett, Emmanuel Balandya, Kien Alfred Mteta, Blandina Theophil Mmbaga
Background: Bacterial urinary tract infection (BUTI) is the commonest urinary tract infection among people living with human immunodeficiency virus (PLHIV). It causes significant morbidity in this vulnerable group. Immunosuppression due to HIV can mask the signs and symptoms of infection leading to asymptomatic disease. There is limited evidence in Tanzania regarding BUTI and PLHIV. This study aimed to determine the prevalence, etiology, risk factors and susceptibility pattern of isolates causing asymptomatic UTI in PLHIV at Kilimanjaro Christian Medical Centre (KCMC)...
2021: Infection and Drug Resistance
https://read.qxmd.com/read/33402950/prevalence-and-antibiotic-susceptibility-pattern-of-bacteriuria-among-hiv-seropositive-patients-attending-the-bamenda-regional-hospital-cameroon
#20
JOURNAL ARTICLE
Moses Samje, Onesimus Yongwa, Alice Mbi Enekegbe, Simon Njoya
Background: HIV causes a decrease in CD4+ lymphocyte cells count, exposing the individual to infections (urinary tract infections). This study was carried out to determine the prevalence of bacteriuria and antimicrobial susceptibility pattern of bacteria isolates among HIV patients. Methods: Clean catch mid-stream urine samples were collected from 135 HIV- seropositive patients, cultured on Cystein lactose electrolyte deficient (CLED) agar and incubated at 370C for 24 hours...
September 2020: African Health Sciences
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