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https://www.readbyqxmd.com/read/29149018/please-wait-processing-a-selective-literature-review-of-the-neurological-understanding-of-emotional-processing-in-asd-and-its-potential-contribution-to-neuroeducation
#1
REVIEW
Eric Shyman
Autism spectrum disorder (ASD) and its corresponding conditions have been investigated from a multitude of perspectives resulting in varying understandings of its origin, its outplay, its prognosis, and potential methods of intervention and education for individuals with the disorder. One area that has contributed significantly to providing a different type of understanding is that of neuroscience, and specifically neuroimaging. This paper will offer a selective literature review of research that investigates the role of emotional processing in ASD, and how a deepening of this line of understanding can be used to inform more comprehensive educational practices...
November 17, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29134267/complement-in-the-pathogenesis-of-alzheimer-s-disease
#2
REVIEW
B Paul Morgan
The emergence of complement as an important player in normal brain development and pathological remodelling has come as a major surprise to most scientists working in neuroscience and almost all those working in complement. That a system, evolved to protect the host against infection, should have these unanticipated roles has forced a rethink about what complement might be doing in the brain in health and disease, where it is coming from, and whether we can, or indeed should, manipulate complement in the brain to improve function or restore homeostasis...
November 13, 2017: Seminars in Immunopathology
https://www.readbyqxmd.com/read/29111001/the-professional-practice-and-training-of-neurology-in-the-asian-and-oceanian-region-a-cross-sectional-survey-by-the-asian-and-oceanian-association-of-neurology-aoan
#3
Artemio Roxas, Man Mohan Mehndiratta, Natan Bornstein, Richard Macdonell, Kheng Seang Lim, Ping-Wing Ng, Shuren Dashzeveg, Hidehiro Mizusawa, Hamed Esmatullah, Shey Lin Wu, Christopher Chen, Mohammad Kurniawan, Joung-Ho Rha, Mohammad Wasay, Niphon Poungvarin, Saman Gunatilake, Nguyen Huy Thang
OBJECTIVE: To survey AOAN member countries regarding their organizational structure, postgraduate neurology training program, and resources for neurological care provision. METHODOLOGY: A cross-sectional survey using a 36-item questionnaire was conducted among country representatives to AOAN from August 2015 to August 2016. RESULTS: A total of 18/20 AOAN member countries participated in the survey. All the countries have organized association with regular meetings, election of officers and neurology training program...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29110344/current-technical-approaches-to-brain-energy-metabolism
#4
REVIEW
L Felipe Barros, Juan P Bolaños, Gilles Bonvento, Anne-Karine Bouzier-Sore, Angus Brown, Johannes Hirrlinger, Sergey Kasparov, Frank Kirchhoff, Anne N Murphy, Luc Pellerin, Michael B Robinson, Bruno Weber
Neuroscience is a technology-driven discipline and brain energy metabolism is no exception. Once satisfied with mapping metabolic pathways at organ level, we are now looking to learn what it is exactly that metabolic enzymes and transporters do and when, where do they reside, how are they regulated, and how do they relate to the specific functions of neurons, glial cells, and their subcellular domains and organelles, in different areas of the brain. Moreover, we aim to quantify the fluxes of metabolites within and between cells...
November 7, 2017: Glia
https://www.readbyqxmd.com/read/29109247/highly-scalable-multichannel-mesh-electronics-for-stable-chronic-brain-electrophysiology
#5
Tian-Ming Fu, Guosong Hong, Robert D Viveros, Tao Zhou, Charles M Lieber
Implantable electrical probes have led to advances in neuroscience, brain-machine interfaces, and treatment of neurological diseases, yet they remain limited in several key aspects. Ideally, an electrical probe should be capable of recording from large numbers of neurons across multiple local circuits and, importantly, allow stable tracking of the evolution of these neurons over the entire course of study. Silicon probes based on microfabrication can yield large-scale, high-density recording but face challenges of chronic gliosis and instability due to mechanical and structural mismatch with the brain...
November 6, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29101377/a-high-throughput-model-for-investigating-neuronal-function-and-synaptic-transmission-in-cultured-neuronal-networks
#6
Jasmeet K Virdee, Gabriella Saro, Antoine Fouillet, Jeremy Findlay, Filipa Ferreira, Sarah Eversden, Michael J O'Neill, Joanna Wolak, Daniel Ursu
Loss of synapses or alteration of synaptic activity is associated with cognitive impairment observed in a number of psychiatric and neurological disorders, such as schizophrenia and Alzheimer's disease. Therefore successful development of in vitro methods that can investigate synaptic function in a high-throughput format could be highly impactful for neuroscience drug discovery. We present here the development, characterisation and validation of a novel high-throughput in vitro model for assessing neuronal function and synaptic transmission in primary rodent neurons...
November 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29073084/disruption-and-rescue-of-interareal-theta-phase-coupling-and-adaptive-behavior
#7
Robert M G Reinhart
Rescuing executive functions in people with neurological and neuropsychiatric disorders has been a major goal of psychology and neuroscience for decades. Innovative computer-training regimes for executive functions have made tremendous inroads, yet the positive effects of training have not always translated into improved cognitive functioning and often take many days to emerge. In the present study, we asked whether it was possible to immediately change components of executive function by directly manipulating neural activity using a stimulation technology called high-definition transcranial alternating current stimulation (HD-tACS)...
October 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29060779/hemodynamic-response-to-optogenetic-stimulation-varied-under-different-stimulus-parameters
#8
B Bo, W Li, Y Wang, Y Li, S Tong
The coupling between neuronal activity and cerebral blood flow(CBF), known as neurovascular coupling, serves as the basis of functional brain imaging. Optogenetics provides a precise and selective approach to manipulate the activity in cell-specific neurons. It has been used in neuroscience research for comprehensive understanding about the light-evoked neurovascular coupling in rodent neuronal circuits. However, the spatiotemporal CBF response characteristics under different stimulus parameters such as pulse width and frequency remains unclear due to the lack of efficient CBF imaging technology...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060073/research-on-the-synchronous-detection-of-neuronal-signals-under-a-nerve-stimulation-system-control
#9
Yu Zhang, Shengwei Xu, Lili Yang, Guihua Xiao, Song Zhang, Fei Gao, Ziyue Li, Mixia Wang, Yilin Song, Xinxia Cai
Deep brain stimulation (DBS) provides a recognized research intervention for neurological disease currently. However, there is a lack of traditional electrical stimulator to observe neuronal firing activity synchronously. The aim of the present study was to realize concurrent detection of neuronal signals better under a nerve stimulation system control. Herein, we designed an integrated software, which could control not only neuro-stimulator but also detection instrument at the same time. Moreover, the actual stimulation signals applied to the experiment object could be collected back to data acquisition card and in consistent with the electrophysiological signals...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057385/a-network-neuroscience-of-neurofeedback-for-clinical-translation
#10
Andrew C Murphy, Danielle S Bassett
In the emerging field of network neuroscience, the brain is represented as a network of discrete yet functionally and structurally interconnected areas. Mathematical and computational tools to characterize the organization of this network can provide insights into the principles guiding brain structure and function, and can pinpoint differences between healthy individuals and individuals suffering from psychiatric disease or neurological disorders. The field is now faced with the question of how to devise clinical interventions that target these network alterations...
March 2017: Curr Opin Biomed Eng
https://www.readbyqxmd.com/read/29054772/through-clinical-observation-the-history-of-priapism-after-spinal-cord-injuries
#11
REVIEW
Mihaela Dana Turliuc, Serban Turliuc, Andrei Ionut Cucu, Camelia Tamas, Alexandru Carauleanu, Catalin Buzduga, Anca Sava, Gabriela Florenta Dumitrescu, Claudia Florida Costea
Since ancient times, the physicians of Antiquity noted the occurrence of priapism in some spinal cord injuries. Although priests saw it as a consequence of curses and witchcraft, after clinical observations of the Middle Ages and Renaissance, first medical hypotheses emerged in the 17(th)-19(th) centuries completed and argued by neuroscience and neurology developed in the European laboratories and hospitals. This study aims to present a short overview of the history of clinical observations of posttraumatic male priapism after spinal cord injuries since Antiquity until the beginning of the 20(th) century...
October 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29045403/mentalized-affectivity-a-new-model-and-assessment-of-emotion-regulation
#12
David M Greenberg, Jonela Kolasi, Camilla P Hegsted, Yoni Berkowitz, Elliot L Jurist
Here we introduce a new assessment of emotion regulation called the Mentalized Affectivity Scale (MAS). A large online adult sample (N = 2,840) completed the 60-item MAS along with a battery of psychological measures. Results revealed a robust three-component structure underlying mentalized affectivity, which we labeled: Identifying emotions (the ability to identify emotions and to reflect on the factors that influence them); Processing emotions (the ability to modulate and distinguish complex emotions); and Expressing emotions (the tendency to express emotions outwardly or inwardly)...
2017: PloS One
https://www.readbyqxmd.com/read/29037334/an-international-curriculum-for-neuropsychiatry-and-behavioural-neurology
#13
Perminder Sachdev, Adith Mohan
With major advances in neuroscience in the last three decades, there is an emphasis on understanding disturbances in thought, behaviour and emotion in terms of their neuroscientific underpinnings. While psychiatry and neurology, both of which deal with brain diseases, have a historical standing as distinct disciplines, there has been an increasing need to have a combined neuropsychiatric approach to deal with many conditions and disorders. Additionally, there is a body of disorders and conditions that warrants the skills sets and knowledge bases of both disciplines...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29032089/transcranial-magnetic-stimulation-in-basic-and-clinical-neuroscience-a-comprehensive-review-of-fundamental-principles-and-novel-insights
#14
REVIEW
Antoni Valero-Cabré, Julià L Amengual, Chloé Stengel, Alvaro Pascual-Leone, Olivier A Coubard
Non-invasive brain stimulation methods, such as Transcranial Magnetic Stimulation (TMS), are widely used worldwide to make causality-based inferences about brain-behavior interactions. TMS-based clinical applications have been shown promising to treat neurological or psychiatric diseases. TMS works by inducing non-invasively electric currents in localized cortical regions thus modulating their excitability levels and ongoing activity patterns depending on stimulation settings: frequency, number of pulses, train duration and intertrain intervals...
October 13, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28987462/the-developing-utility-of-zebrafish-models-of-neurological-and-neuropsychiatric-disorders-a-critical-review
#15
REVIEW
Barbara D Fontana, Nathana J Mezzomo, Allan V Kalueff, Denis B Rosemberg
Zebrafish (Danio rerio) have become a powerful tool in neuroscience research due to their genetic tractability, molecular/physiological conservation, small body size, ease of experimental manipulations in vivo, and rich behavioral repertoire. Zebrafish models and tests are particularly useful in genetics research, neurophenotyping, CNS drug screening, as well as modeling complex neurological and psychiatric disorders. Here, we discuss selected examples of successful application of zebrafish models to mimicking various aspects of brain pathology, and emphasize their developing utility for studying the underlying molecular and genetic mechanisms...
October 5, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28975039/creative-music-therapy-to-promote-brain-structure-function-and-neurobehavioral-outcomes-in-preterm-infants-a-randomized-controlled-pilot-trial-protocol
#16
Friederike Barbara Haslbeck, Hans-Ulrich Bucher, Dirk Bassler, Cornelia Hagmann
BACKGROUND: Preterm birth is associated with increased risk of neurological impairment and deficits in cognition, motor function, and behavioral problems. Limited studies indicate that multi-sensory experiences support brain development in preterm infants. Music appears to promote neurobiological processes and neuronal learning in the human brain. Creative music therapy (CMT) is an individualized, interactive therapeutic approach based on the theory and methods of Nordoff and Robbins...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28973530/neurosurgical-patients-as-human-research-subjects-ethical-considerations-in-intracranial-electrophysiology-research
#17
Winston Chiong, Matthew K Leonard, Edward F Chang
Intracranial electrical recordings and stimulation of neurosurgical patients have been central to the advancement of human neuroscience. The use of these methods has rapidly expanded over the last decade due to theoretical and technical advances, as well as the growing number of neurosurgical patients undergoing functional procedures for indications such as epilepsy, tumor resection, and movement disorders. These methods pose the potential for ethical conflict, as they involve basic neuroscientific research utilizing invasive procedures in human patients undergoing treatment for neurological illnesses...
July 22, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28971385/biological-relevance-of-network-architecture
#18
Ioannis Gkigkitzis, Ioannis Haranas, Ilias Kotsireas
Mathematical representations of brain networks in neuroscience through the use of graph theory may be very useful for the understanding of neurological diseases and disorders and such an explanatory power is currently under intense investigation. Graph metrics are expected to vary across subjects and are likely to reflect behavioural and cognitive performances. The challenge is to set up a framework that can explain how behaviour, cognition, memory, and other brain properties can emerge through the combined interactions of neurons, ensembles of neurons, and larger-scale brain regions that make information transfer possible...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28961088/cross-disciplinary-medical-advances-with-neuroengineering-challenges-spur-development-of-unique-rehabilitative-and-therapeutic-interventions
#19
Sherif Elbasiouny
Neuroengineering brings tools and techniques from the engineering fields into neuroscience to create new approaches for investigating the central nervous system (CNS). This fusion of disciplines is advancing our knowledge of how the CNS works and how we can enhance our natural cognitive and emotional function and restore neurological functions that are compromised by disease or injury.
September 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28957666/the-neurovascular-unit-coming-of-age-a-journey-through-neurovascular-coupling-in-health-and-disease
#20
REVIEW
Costantino Iadecola
The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress Review Group meeting of the National Institute of Neurological Disorders and Stroke, emphasizes the intimate relationship between the brain and its vessels. Since then, the NVU has attracted the interest of the neuroscience community, resulting in considerable advances in the field. Here the current state of knowledge of the NVU will be assessed, focusing on one of its most vital roles: the coupling between neural activity and blood flow...
September 27, 2017: Neuron
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