keyword
MENU ▼
Read by QxMD icon Read
search

Neuroscience neurology

keyword
https://www.readbyqxmd.com/read/29773777/seeking-biomarkers-of-early-childhood-malnutrition-s-long-term-effects
#1
Pedro A Valdés-Sosa, Janina R Galler, Cyralene P Bryce, Arielle G Rabinowitz, María L Bringas-Vega, Nibaldo Hernández-Mesa, Alberto Taboada-Crispi
Protein-energy malnutrition affects one in nine people worldwide and is most prevalent among children aged less than five years in low-income countries. Early childhood malnutrition can have damaging neurodevelopmental effects, with significant increases in cognitive, neurological and mental health problems over the lifespan, outcomes which can also extend to the next generation. This article describes a research collaboration involving scientists from five centers in Barbados, China, Cuba and the USA. It builds on longer-term joint work between the Barbados Nutrition Study (which, over a 45-year span, has extensively documented nutritional, health, behavioral, social and economic outcomes of individuals who experienced protein-energy malnutrition in the first year of life and healthy controls from the same classrooms and neighborhoods) and the Cuban Neuroscience Center (which has developed low-cost brain imaging methods that can be readily used in low income settings to identify biomarkers for early detection and treatment of adverse consequences of childhood malnutrition)...
April 2018: MEDICC Review
https://www.readbyqxmd.com/read/29757270/establishing-mouse-models-for-zika-virus-induced-neurological-disorders-using-intracerebral-injection-strategies-embryonic-neonatal-and-adult
#2
Stephanie A Herrlinger, Qiang Shao, Li Ma, Melinda Brindley, Jian-Fu Chen
The Zika virus (ZIKV) is a flavivirus currently endemic in North, Central, and South America. It is now established that the ZIKV can cause microcephaly and additional brain abnormalities. However, the mechanism underlying the pathogenesis of ZIKV in the developing brain remains unclear. Intracerebral surgical methods are frequently used in neuroscience research to address questions about both normal and abnormal brain development and brain function. This protocol utilizes classical surgical techniques and describes methods that allow one to model ZIKV-associated human neurological disease in the mouse nervous system...
April 26, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29742814/optogenetic-stimulation-understanding-memory-and-treating-deficits
#3
S C Barnett, B A L Perry, J C Dalrymple-Alford, L C Parr-Brownlie
Technology allowing genetically targeted cells to be modulated by light has revolutionised neuroscience in the past decade, and given rise to the field of optogenetic stimulation. For this, non-native, light activated proteins (e.g. channelrhodopsin) are expressed in a specific cell phenotype (e.g. glutamatergic neurons) in a subset of central nervous system nuclei, and short pulses of light of a narrow wavelength (e.g. blue, 473 nm) are used to modulate cell activity. Cell activity can be increased or decreased depending on which light activated protein is used...
May 9, 2018: Hippocampus
https://www.readbyqxmd.com/read/29738432/neuroimmunology-research-a-report-from-the-cuban-network-of-neuroimmunology
#4
María de Los Angeles Robinson-Agramonte, Lourdes Lorigados Pedre, Orlando Ramón Serrano-Barrera
Neuroimmunology can be traced back to the XIX century through the descriptions of some of the disease’s models (e.g., multiple sclerosis and Guillain Barret syndrome, amongst others). The diagnostic tools are based in the cerebrospinal fluid (CSF) analysis developed by Quincke or in the development of neuroimmunotherapy with the earlier expression in Pasteur’s vaccine for rabies. Nevertheless, this field, which began to become delineated as an independent research area in the 1940s, has evolved as an innovative and integrative field at the shared edges of neurosciences, immunology, and related clinical and research areas, which are currently becoming a major concern for neuroscience and indeed for all of the scientific community linked to it...
May 8, 2018: Behavioral Sciences
https://www.readbyqxmd.com/read/29733950/recent-advances-in-carrier-mediated-nose-to-brain-delivery-of-pharmaceutics
#5
REVIEW
Vassilis Bourganis, Olga Kammona, Aleck Alexopoulos, Costas Kiparissides
Central nervous system (CNS) disorders (e.g., multiple sclerosis, Alzheimer's disease, etc.) represent a growing public health issue, primarily due to the increased life expectancy and the aging population. The treatment of such disorders is notably elaborate and requires the delivery of therapeutics to the brain in appropriate amounts to elicit a pharmacological response. However, despite the major advances both in neuroscience and drug delivery research, the administration of drugs to the CNS still remains elusive...
May 4, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29729527/the-hippocampus-in-depth-a-sublayer-specific-perspective-of-entorhinal-hippocampal-function
#6
REVIEW
Manuel Valero, Liset Menendez de la Prida
Understanding how the brain represents events is a fundamental question in neuroscience. The entorhinal-hippocampal system is central to such representations, which are severely compromised in some neurological diseases. In spite of much progress, a comprehensive, integrated view of spatial, temporal and other aspects of episodic representation remains elusive. Here, we review recent data on the role of cell-type specific entorhinal inputs which excite deep and superficial CA1 pyramidal cells by direct and indirect pathways...
May 2, 2018: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29720792/preventing-neurophobia-remodeling-neurology-education-for-21-st-century-medical-students-through-effective-pedagogical-strategies-for-neurophilia
#7
REVIEW
Bhaskara P Shelley, Thomas V Chacko, Balakrishnan R Nair
Neurology has a reputation, particularly as a complex "head-to-toe" discipline for undergraduate medical students. Neurophobia syndrome, a global phenomenon, fundamentally stems from pedagogical deficiencies during the undergraduate curriculum, the lack of vertical integration between basic neurosciences and clinical bedside neurology, the lack of clinical reasoning exercises, cognitive heuristics, and clinical problem-solving, errors in diagnostic competence, and hyposkilia. This ultimately results in poor clinical competence and proficiency in clinical neurology and causes attrition in nurturing a passion for learning the neurology discipline...
January 2018: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29717896/the-importance-of-food-nutrition-and-physical-activity-in-cancer-prevention-an-interview-with-dr-kate-allen
#8
Kate Allen
Kate Allen speaks to Roshaine Wijayatunga, Managing Commissioning Editor. Dr Kate Allen works as an Executive Director in Science and Public Affairs at World Cancer Research Fund International ( http://wcrf.org ), an NGO and leading authority in the field of cancer prevention through diet, weight and physical activity. Kate is responsible for the organization's scientific, policy and conference programs in the areas of food, nutrition, physical activity and weight management. An important aspect of her role is helping to create collaborative relationships and activities across the WCRF national charities (in Europe, America and Asia) in these areas, as well as maintaining and creating external partnerships...
May 2, 2018: Future Oncology
https://www.readbyqxmd.com/read/29707189/a-review-of-robotics-in-neurorehabilitation-towards-an-automated-process-for-upper-limb
#9
REVIEW
E D Oña, R Cano-de la Cuerda, P Sánchez-Herrera, C Balaguer, A Jardón
Robot-mediated neurorehabilitation is a growing field that seeks to incorporate advances in robotics combined with neuroscience and rehabilitation to define new methods for treating problems related with neurological diseases. In this paper, a systematic literature review is conducted to identify the contribution of robotics for upper limb neurorehabilitation, highlighting its relation with the rehabilitation cycle, and to clarify the prospective research directions in the development of more autonomous rehabilitation processes...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29705849/application-of-chemogenetics-and-optogenetics-to-dissect-brain-immune-interactions
#10
Ben Korin, Asya Rolls
For many years, the complexity and multifactorial nature of brain-immune interactions limited our ability to dissect their underlying mechanisms. An especially challenging question was how the brain controls immunity, since the repertoire of techniques to control the brain's activity was extremely limited. New tools, such as optogenetics and chemogenetics (e.g., DREADDs), developed over the last decade, opened new frontiers in neuroscience with major implications for neuroimmunology. These tools enable mapping the causal effects of activating/attenuating defined neurons in the brain, on the immune system...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29705626/the-montreal-procedure-the-legacy-of-the-great-wilder-penfield
#11
REVIEW
Lady Diana Ladino, Syed Rizvi, José Francisco Téllez-Zenteno
Wilder Penfield pioneered the early practice of brain surgery. In binding together the disciplines of neurosurgery, neurology, neuropathology, psychology, and related basic sciences, Penfield transformed our understanding of the field of neuroscience. He brought to the operating room the meticulous techniques of Sherrington, combined with methods of stimulation described by Foerster, which he complemented with expert knowledge of the neurocytology of nervous tissue. While developing surgical treatments for epilepsy, Penfield began to map the brain...
April 26, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29700773/correction-to-transplantation-of-human-chorion-derived-cholinergic-progenitor-cells-a-novel-treatment-for-neurological-disorders
#12
Alireza Mohammadi, Ali Maleki-Jamshid, Davood Sanooghi, Peiman Brouki Milan, Arash Rahmani, Farshid Sefat, Koorosh Shahpasand, Mansoureh Soleimani, Mehrdad Bakhtiari, Rafie Belali, Faezeh Faghihi, Mohammad Taghi Joghataei, George Perry, Masoud Mozafari
The original version of this article unfortunately contained mistake in the affiliation. Affiliation 1 should be read as "Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran". The original article has been corrected.
April 26, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29694315/is-intelligence-equivalent-to-executive-functions
#13
Alfredo Ardila
BACKGROUND: Since the mid 19th century, cognitive and behavioral neurosciences have attempted to find the neurological bases of intellectual abilities. During the early 20th century the psychometric concept of "intelligence" was coined; and toward the end of the 20th century the neuropsychological concept of "executive functions" was introduced. Controversies, however, remain about the unity or heterogeneity of so-called executive functions. METHODS: It is proposed that two major executive functions could be separated: metacognitive -or intelectual- and emotional/motivational...
May 2018: Psicothema
https://www.readbyqxmd.com/read/29693233/management-of-optic-neuritis-in-ireland-a-survey-comparing-the-management-practices-of-acute-demyelinating-optic-neuritis-amongst-ophthalmologists-and-neurologists-in-ireland
#14
Lina Kobayter, Shivona Chetty
BACKGROUND: Acute optic neuritis (ON) is often the first manifestation of multiple sclerosis which is particularly common in Ireland. Despite the specific clinical details regarding investigations and management of ON provided by the Optic Neuritis Treatment Trial (ONTT), international surveys have shown that there are still notable differences in the management of ON between neurologists and ophthalmologists. AIM: To compare the investigation and treatment of acute optic neuritis between ophthalmologists and neurologists in Ireland METHOD: A survey consisting of a case scenario and questions regarding treatment and investigations of a patient with ON was emailed to ophthalmology consultants, trainees and medical ophthalmologists registered with the Irish College of Ophthalmologists and to neurology consultants and registrars registered with the Irish Institute of Clinical Neuroscience...
April 24, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29652315/-music-therapy-procedures-controlled-by-the-brain-potentials-in-treatment-of-functional-disorders
#15
A A Zemlyanaya, G S Radchenko, A I Fedotchev
Twenty years ago, the Korsakov's Journal of Neurology and Psychiatry has published the article of Ya.I. Levin 'Brain music in the treatment of patients with insomnia'. This publication was the starting point for an innovative approach to preventing and correcting functional disorders of a person via musical or music-like stimuli that are controlled by the brain potentials of patient's. This approach called 'Music of the brain' is fully consistent with modern ideas about preventive neuroscience as a new field of scientific research at the intersection of neuroscience and preventive medicine...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29627761/following-the-patient-s-orders-recommending-vs-offering-choice-in-neurology-outpatient-consultations
#16
Paul Chappell, Merran Toerien, Clare Jackson, Markus Reuber
The UK's Royal College of Surgeons (2016) has argued that health professionals must replace a 'paternalistic' approach to consent with 'informed choice'. We engage with these guidelines through analysis of neurology consultations in two UK-based neuroscience centres, where informed choice has been advocated for over a decade. Based on 223 recorded consultations and related questionnaire data (collected in 2012), we used conversation analysis (CA) to identify two practices for offering choice: patient view elicitors (PVEs) and option-lists...
March 26, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29623154/choosing-wisely-together-physical-and-occupational-therapy-consultation-for-acute-neurology-inpatients
#17
John C Probasco, Annette Lavezza, Andre Cassell, Tenise Shakes, Angie Feurer, Holly Russell, Hilary Sporney, Margie Burnett, Chepkorir Maritim, Victor Urrutia, H Adrian Puttgen, Michael Friedman, Erik H Hoyer
Background: Although many hospitalized neuroscience patients have physical and occupational therapy (rehabilitation) needs, patients with none or minimal physical impairments frequently receive rehabilitation consultation, diverting from patients with greatest need. Methods: A multidisciplinary team on the general and cerebrovascular neurology acute inpatient services mapped the rehabilitation consultation process, resulting in multiple implemented interventions including physician education on appropriate acute rehabilitation consultations, modification of multidisciplinary rounds, and discussion of patient rehabilitation needs throughout hospitalization...
April 2018: Neurohospitalist
https://www.readbyqxmd.com/read/29622559/who-s-contributing-most-to-american-neuroscience-journals-american-or-foreign-authors
#18
P Charkhchi, M Mirbolouk, R Jalilian, D M Yousem
BACKGROUND AND PURPOSE: With globalization, the contributions of authors from abroad to the American published literature has increased. We sought to determine the changes with time in the proportional contributions of American and non-American authors in the American neurosciences literature. We hypothesized the following: 1) During the past 21 years, manuscript contributions of American institutions have proportionally decreased in neuroradiology, more than in neurosurgery or neurology; 2) contributions of Asian institutions have affected neuroradiology more than neurosurgery and neurology; and 3) American articles garner more citations...
April 5, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29611254/oxytocin-levels-in-saliva-correlate-better-than-plasma-levels-with-concentrations-in-the-cerebrospinal-fluid-of-patients-in-neurocritical-care
#19
Jan Martin, Simone M Kagerbauer, Jens Gempt, Armin Podtschaske, Alexander Hapfelmeier, Gerhard Schneider
In the converging fields of neuroendocrinology and behavioural neuroscience, the interaction between peripheral secretion and central release of oxytocin in humans has not yet been comprehensively assessed. As the human brain is not directly accessible and as the collection of human cerebrospinal fluid (CSF) usually requires invasive procedures, easier accessible compartments such as blood or saliva attract increasing attention. In this study, we prospectively determined oxytocin concentrations in the three compartments plasma, CSF and saliva of fifty critically ill patients with neurological and neurosurgical diseases...
April 3, 2018: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29589121/sigmund-freud-early-network-theories-of-the-brain
#20
REVIEW
Werner Surbeck, Tim Killeen, Johannes Vetter, Gerhard Hildebrandt
Since the early days of modern neuroscience, psychological models of brain function have been a key component in the development of new knowledge. These models aim to provide a framework that allows the integration of discoveries derived from the fundamental disciplines of neuroscience, including anatomy and physiology, as well as clinical neurology and psychiatry. During the initial stages of his career, Sigmund Freud (1856-1939), became actively involved in these nascent fields with a burgeoning interest in functional neuroanatomy...
March 27, 2018: Acta Neurochirurgica
keyword
keyword
47778
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"