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Florian Ernst Martin Herrmann, Petra Wellmann, Sebastian Sadoni, René Schramm, Christian Hagl, Gerd Juchem
INTRODUCTION: We investigated the development of sinus node dysfunction (SND) requiring pacemaker implantation after heart transplant (HTx) especially regarding pacing burden in these patients. PATIENTS AND METHODS: Patients requiring a pacemaker for SND were compared to all other patients in an HTx cohort including transplant patients from 1981-2016. RESULTS: SND requiring pacemaker implantation developed in 118 patients (10%). These patients had received a biatrial anastomosis more frequently than those in the No SND group 95...
January 18, 2018: Clinical Transplantation
Changyou Wang, Jinqiang Guo, Shengkang Liang, Yunfei Wang, Yanqun Yang, Xiulin Wang
The concentrations of the potentially toxic dissolved elements (PTEs) As, Hg, Cr, Pb, Cd, and Cu in the main rivers into Jiaozhou Bay (JZB) during 1981-2006 were measured, and the impact of the fluvial PTE fluxes on their distributions in the bay was investigated. The overall average concentration in the rivers into JZB ranged from 8.8 to 39.6 μg L-1 for As, 10.1 to 632.6 ng L-1 for Hg, 4.1 to 3003.6 μg L-1 for Cr, 8.5 to 141.9 μg L-1 for Pb, 1.1 to 34.2 μg L-1 for Cd, and 13.2 to 1042.8 μg L-1 for Cu...
January 12, 2018: Environmental Science and Pollution Research International
James P Fischer, Austin E Wininger, David C Scofield, Aamir Tucker, Ethan J Kacena-Merrell, Elizabeth C Whipple, Melissa A Kacena, Randall T Loder
BACKGROUND: Orthopaedics is the clinical discipline with the lowest percentage of female residents and faculty. Pediatric orthopaedics has a higher percentage of women than other orthopaedic subspecialties. It was the purpose of this study to examine bibliometric trends in the Journal of Pediatric Orthopaedics (JPO) with a specific focus on sex. METHODS: A bibliometeric analysis for the years 2015, 2005, 1995, 1985, 1981 was performed. The names of first and corresponding authors; corresponding author position; country of origin; number of institutions, countries, authors, printed pages, and references was tabulated...
January 6, 2018: Journal of Pediatric Orthopedics
Mehdi Assmar, Marjan Keypour, Mehdi Rohani, Ehsan Mostafavi, Dariush Daneshvar Farhud
Background: The present study was conducted approximately 40 years ago, but its results have not been released. At the time of this study, the importance of the gut microbiota was not fully understood. Methods: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in Iran, were compared in a disease endemic area (Akanlu, Hamadan, western Iran) and a non-endemic zone (Telo, Tehran, Iran) from 1977 to 1981. Results: This study was able to transmit the resistance to Y...
January 2018: Iranian Journal of Public Health
Monika Sparber-Sauer, Guido Seitz, Thekla von Kalle, Christian Vokuhl, Ivo Leuschner, Monika Scheer, Marc Münter, Gustaf Ljungman, Stefan S Bielack, Felix Niggli, Ruth Ladenstein, Thomas Klingebiel, Joerg Fuchs, Ewa Koscielniak
BACKGROUND: Treatment algorithms for patients with aggressive fibromatosis (AF) are challenging. There are limited data available about the use of systemic therapy (ST) in pediatric patients with AF. METHODS: Patient-, tumor-, and treatment-related factors of 90 children and adolescents with AF treated on multiple prospective trials of the Cooperative Weichteilsarkom Studiengruppe (1981-2015) were analyzed with focus on response and outcome of ST. RESULTS: Median age was 9...
January 5, 2018: Pediatric Blood & Cancer
Justin J Lang
Emerging evidence has demonstrated the strong link between cardiorespiratory fitness and multiple aspects of health (i.e., physiological, physical, psychosocial, cognitive), independent of physical activity, among school-aged children and youth. Cardiorespiratory fitness is a trait that does not vary substantially from day-to-day, and provides an indication of recent physical activity levels, making it an important possible indicator of population health. Thus, the objective of this dissertation was to investigate the utility of cardiorespiratory fitness, measured using the 20-m shuttle run test, as a broad, holistic health indicator for population health surveillance among children and youth...
January 9, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Federico Venuta, Dirk Van Raemdonck
Lung transplantation nowadays is a well-accepted and routine treatment for well selected patients with terminal respiratory disease. However, it took several decades of experimental studies and clinical attempts to reach this success. In this paper, we describe the early experimental activity from the mid-forties until the early sixties. The first clinical attempt in humans was reported by Hardy and Webb in 1963 followed by others with short survival only except for one case by Derom et al. who lived for 10 months...
December 2017: Journal of Thoracic Disease
Grigoris Rousakis, Ioannis P Panagiotopoulos, Paraskevi Drakopoulou, Panos Georgiou, Dimitrios Nikolopoulos, Nikolaos Mporompokas, Vasilios Kapsimalis, Isidoros Livanos, Ioannis A Morfis, Christos Anagnostou, Maria Koutra
The modern climate trend and population growth have dramatically increased the need for maximization of the net benefit from the existing storage space in freshwater reservoirs. However, sedimentation in reservoirs through physical deposition and/or slope failures is a major threat to their productivity and life expectancy. In this context, the sedimentation impact on the sustainability of Mornos Lake/Reservoir, which is exceptionally vital for the ~ 3.1 million inhabitants of Athens, had to be evaluated...
January 6, 2018: Environmental Monitoring and Assessment
Fereidoun Azizi, Atieh Amouzegar
BACKGROUND: Diffuse toxic goiter accounts for about 15% of all childhood thyroid diseases. There is great controversy over the management of Graves' disease in children and adolescents. This article reports our experience in 304 children and juvenile patients with Graves' disease. METHODS: Between 1981 and 2015, 304 patients aged 5-19 years with diffuse toxic goiter were studied, of whom 296 patients were treated with antithyroid drugs (ATD) for 18 months. Patients with persistent or relapsed hyperthyroidism who refused ablative therapy with surgery or radioiodine were managed with continuous methimazole (MMI) treatment...
January 8, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
Gholamreza Roshandel, Shahryar Semnani, Abdolreza Fazel, Mohammadreza Honarvar, MohammadHossein Taziki, SeyedMehdi Sedaghat, Nafiseh Abdolahi, Mohammad Ashaari, Mohammad Poorabbasi, Susan Hasanpour, SeyedAhmad Hosseini, SeyedMohsen Mansuri, Ataollah Jahangirrad, Sima Besharat, Abbas Moghaddami, Honeyehsadat Mirkarimi, Faezeh Salamat, Fatemeh Ghasemi-Kebria, Nastaran Jafari, Nesa Shokoohifar, Masoomeh Gholami, Alireza Sadjadi, Hossein Poustchi, Freddie Bray, Reza Malekzadeh
INTRODUCTION: The Golestan population-based cancer registry (GPCR) was established in Golestan province, Northern Iran, within the Asian belt with predominance of upper-gastrointestinal cancers. We aimed to present the experiences of the registry in a resource-limited setting over the 10 years since its inception (2004-2013). METHODS: The GPCR was established as a research project to enable sustainable funding. A clear plan was developed for use of the GPCR data...
January 4, 2018: Cancer Epidemiology
Laura Wirth, Alexander Klein, Andrea Baur-Melnyk, Thomas Knösel, Lars H Lindner, Falk Roeder, Volkmar Jansson, Hans Roland Dürr
BACKGROUND: Desmoid-type fibromatosis (DF) is a aggressive (myo)fibroblastic neoplasm with an infiltrative growth and a tendency to local recurrence. Resection of the tumour and/or radiation were proposed as principal treatment. The aim of this retrospective study was to analyze the local control rates focusing on the effect of surgical margins and radiotherapy. METHODS: From 1981 to 2014, 44 patients had been treated. Fifty four therapies had been applied, in 50 cases surgery +/- radiation therapy, NSAIDs or chemotherapy...
January 5, 2018: BMC Musculoskeletal Disorders
Amr El-Demerdash, Atanas G Atanasov, Anupam Bishayee, Mamdouh Abdel-Mogib, John N A Hooper, Ali Al-Mourabit
Pyrroloquinoline and guanidine-derived alkaloids present distinct groups of marine secondary metabolites with structural diversity that displayed potentialities in biological research. A considerable number of these molecular architectures had been recorded from marine sponges belonging to different marine genera, including Batzella, Crambe, Monanchora, Clathria, Ptilocaulis and New Caledonian starfishes Fromia monilis and Celerina heffernani. In this review, we aim to comprehensively cover the chemodiversity and the bioactivities landmarks centered around the chemical constituents exclusively isolated from these three marine genera including Batzella, Crambe and Monanchora over the period 1981-2017, paying a special attention to the polycyclic guanidinic compounds and their proposed biomimetic landmarks...
January 2, 2018: Nutrients
I Bloch
The development of animal ethics and animal rights from the antiquity up to modern times is described. The relationship of humans to animals was primarily based on fear and animal cult, developed by the domestication to a partnership. The philosophers of the early modern age denied the animals the reason, what was disadvantageous to the position of the animals in the society and the behavior of humans to the animals. By the end of the 19th century the animal protection concept developed with numerous postulates for legal regulations...
January 2018: Schweizer Archiv Für Tierheilkunde
Robert L C Voeten, Iro K Ventouri, Rob Haselberg, Govert Willem Somsen
Since the introduction of modern capillary electrophoresis (CE) by Jorgenson and Lukacs in 1981, CE has evolved into a highly mature and versatile separation technique. After a first decade of development studies and instrument commercialization, CE took its place among established analytical techniques and, for instance, became the method of choice for fast high-resolution DNA sequencing in the nineties of the last century. Although with a considerably smaller footprint than liquid and gas chromatography, CE remains to play an essential role in contemporary analytics...
January 3, 2018: Analytical Chemistry
Chao Su, Yonglong Lu, Tieyu Wang, Xiaotian Lu, Shuai Song, Lei Li, Kifayatullah Khan, Chenchen Wang, Ruoyu Liang
Perfluorooctane sulfonate (PFOS) and related substances are widely used in various industrial and commercial applications in China that ultimately discharge sufficient quantities of PFOS to the environment. It remains unclear how emissions of PFOS ultimately affect its concentrations as well as its fate in the environment. In this study, an improved Berkeley-Trent (BETR) multimedia model is developed to predict the PFOS levels with spatial and temporal distributions on unsteady state mode from 1981 to 2050, by taking the Bohai Rim of China as a case...
December 29, 2017: Environmental Pollution
Darae Ko, Sarah R Preis, Steven A Lubitz, David D McManus, Ramachandran S Vasan, Naomi M Hamburg, Emelia J Benjamin, Gary F Mitchell
Previous studies have reported that orthostatic hypotension (OH) is associated with increased risk of atrial fibrillation (AF). We sought to determine whether the association persists after adjusting for hypertension and other cardiovascular risk factors. We studied the Framingham Heart Study Original cohort participants evaluated between 1981 and 1984 without baseline AF. OH was defined as drop in standing systolic blood pressure (BP) of at least 20 mm Hg or standing diastolic BP of at least 10 mm Hg from their supine values after standing for 2 minutes...
December 11, 2017: American Journal of Cardiology
Barbara Wozniak, Iwona Matraszek-Zuchowska, Sebastian Witek, Jan Zmudzki, Andrzej Posyniak
Thyreostatic compounds, such as thiouracil (TU) are orally active drugs that can be used to increase the weight of cattle before slaughter. Due to potentially teratogenic and carcinogenic effects of their residues on public health, the use of thyreostats in animal production has been banned in the European Union since 1981. Systematic detection of low concentrations of thiouracil in the urine of livestock in many countries is believed to be of endogenous origin due to the use of Brassicaceae plants in the animal diet...
December 26, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Dory Kranz, Abby Ellison, Natasha A Mesinkovska, Angela M Christiano, Maria K Hordinsky, John E Harris
Alopecia areata (AA) is a common autoimmune skin disease that results in the loss of hair on the scalp and elsewhere on the body and affects over 146 million people worldwide at some point in their lives. Founded in 1981, the National Alopecia Areata Foundation is a nonprofit organization that supports research to find a cure or acceptable treatment for AA, supports those with the disease, and educates the public about AA. The National Alopecia Areata Foundation conducts research summits every 2 years to review progress and create new directions in its funded and promoted research...
January 2018: Journal of Investigative Dermatology. Symposium Proceedings
Karina Ivanova, Pavel Zehtindjiev, Jean Mariaux, Dimitar Dimitrov, Boyko B Georgiev
The diversity of the haemosporidian genera Plasmodium, Haemoproteus and Leucocytozoon in birds from rain forests in Madagascar is characterized combining techniques of PCR and microscopy and based on the examination of 72 host individuals of 23 species in 15 families. High total prevalence of haemosporidians (68%) is detected, with Leucocytozoon infections being predominant (59.7%) and lower comparable prevalence of Plasmodium (18.0%) and Haemoproteus (23.6%) infections. Using mitochondrial cytochrome b (cytb) marker, 23 genetically distinct lineages are identified: 9 of Plasmodium spp...
December 16, 2017: Infection, Genetics and Evolution
Rémi Perronne, Isabelle Goldringer
We present and highlight a partitioning procedure based on the Rao quadratic entropy index to assess temporal in situ inter-annual varietal and genetic changes of crop diversity. For decades, Western-European agroecosystems have undergone profound changes, among which a reduction of crop genetic diversity. These changes have been highlighted in numerous studies, but no unified partitioning procedure has been proposed to compute the inter-annual variability in both varietal and genetic diversity. To fill this gap, we tested, adjusted and applied a partitioning procedure based on the Rao quadratic entropy index that made possible to describe the different components of crop diversity as well as to account for the relative acreages of varieties...
December 15, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
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