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https://www.readbyqxmd.com/read/28108991/mucosal-immune-tolerance-at-the-ocular-surface-in-health-and-disease
#1
REVIEW
Jeremías G Galletti, Mauricio Guzmán, Mirta N Giordano
The ocular surface is constantly exposed to environmental irritants, allergens and pathogens, against which it can mount a prompt immune response to preserve its integrity. But to avoid unnecessary inflammation, the ocular surface's mucosal immune system must also discriminate between harmless and potentially dangerous antigens, a seemingly complicated task. Despite its unique features, the ocular surface is a mucosal lining, and as such, it shares some homeostatic and pathophysiological mechanisms with other mucosal surfaces...
January 20, 2017: Immunology
https://www.readbyqxmd.com/read/28105700/derivation-and-validation-of-a-diagnostic-test-for-irritable-bowel-syndrome-using-latent-class-analysis
#2
R Sood, D J Gracie, M J Gold, N To, M I Pinto-Sanchez, P Bercik, P Moayyedi, A C Ford, G R Law
BACKGROUND: The accuracy of symptom-based diagnostic criteria for irritable bowel syndrome (IBS) is modest. AIMS: To derive and validate a new test that utilises latent class analysis. METHODS: Symptom, colonoscopy, and histology data were collected from 1981 patients and 360 patients in two cohorts referred to secondary care for investigation of their gastrointestinal symptoms in Canada and the UK, respectively. Latent class analysis was used to identify naturally occurring clusters in patient-reported symptoms in the Canadian dataset, and the latent class model derived from this was then applied to the UK dataset in order to validate it...
January 20, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28103869/sinularin-induces-dna-damage-g2-m-phase-arrest-and-apoptosis-in-human-hepatocellular-carcinoma-cells
#3
Ting-Wen Chung, Shih-Chao Lin, Jui-Hsin Su, Yu-Kuo Chen, Chi-Chien Lin, Hong-Lin Chan
BACKGROUND: Sinularin isolated from the cultured soft coral Sinularia flexibilis has been reported to exert potent cytotoxic effects against particular types of cancer. This study was carried out to investigate the cytotoxic effects in sinularin-treated human hepatocellular carcinoma cells, HepG2, and to subsequently explore the underlying molecular mechanisms. METHODS: TheMTT (3-[4,5-dimethylthiazol-2-yl]-2, 5-diphenyl- tetrazolium bromide) method was used to evaluate the cytotoxicity of sinularin on HepG2 and Hep3B cell lines...
January 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28101990/a-single-centre-study-of-1779-heart-transplant-patients-factors-affecting-pacemaker-implantation
#4
P Wellmann, F E M Herrmann, C Hagl, G Juchem
BACKGROUND: After around 10 % of heart transplants patients require pacemaker implantation. The bradyarrhythmias causing pacemaker requirement include sinus node dysfunction (SND) and atrioventricular block (AVB). This study sought to define clinical predictors for pacemaker requirement as well as identify differences in the patient groups developing SND and AVB. METHODS: Our operative data base was used to collect retrospective recipient, donor and operative data of all patients receiving orthotopic heart transplants between 1981 and 2016...
January 19, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28099653/erratum-the-genesis-of-the-aids-policy-and-aids-space-in-brazil-1981-1989
#5
(no author information available yet)
[This corrects the article doi: 10.1590/S1518-8787.2016050005801].
December 22, 2016: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28098018/-don-t-be-afraid-to-push-at-doors
#6
(no author information available yet)
Alison Twycross started her nursing career in 1981, volunteering at a local hospice while doing her A levels. A registered adult, mental health and children's nurse, she has worked in nurse education for 21 years and is professor and head of children's nursing at London South Bank University. Ms Twycross has edited three books on research related to managing pain in children, and is the editor of the RCNi journal Evidence-Based Nursing.
January 18, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28095707/variations-in-mesothelioma-mortality-rates-among-migrants-to-australia-and-australian-born
#7
Si Si, Susan Peters, Alison Reid
BACKGROUND: Australia's use and consumption of asbestos occurred at the same time as its immigration boom. Our objective was to investigate mesothelioma death rates among migrants and Australian-born between 1981 and 2012. METHODS: Australian national mesothelioma deaths from 1981 to 2002 and 2006 to 2012 together with national censuses from 1981 to 2011 were extracted and combined. Directly standardised rates and negative binomial regression were applied examining differences in mesothelioma death rates with regard to country of birth...
January 17, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28094888/association-between-body-height-and-month-of-birth-among-women-of-european-origin-in-northern-and-southern-hemispheres
#8
Iwona Rosset, Elżbieta Żądzińska, Dominik Strapagiel, Agnieszka Grzelak, Maciej Henneberg
OBJECTIVES: The purpose of this study was to examine the potential association between month of birth and body height among women in northern and southern hemispheres. METHODS: Body heights of adult women of European origin born between 1935 and 1981 who lived in Poland (N = 3,933) and in Australia (N = 1,118) were examined in relation to month of birth by analysis of variance. RESULTS: No association between month of birth and body height was observed in either Polish or Australian women...
January 17, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28079352/the-way-forward-in-italy-for-iodine
#9
Antonella Olivieri, Caterina DI Cosmo, Simona DE Angelis, Roberto DA Cas, Paolo Stacchini, Augusto Pastorelli, Paolo Vitti
Italy is dealing with iodine deficiency since ancient times. Indeed, iodine deficiency disorders, specifically goiter and cretinism, have been reported in some regions of Northern Italy already in the first century AD. However, a clear relationship between endemic goiter and endemic cretinism was recognized only in 1848 by an "ad hoc" committee appointed by the king of Sardinia, which identified extensive areas afflicted by these disorders in Piedmont, Liguria and Sardinia. With the identification in the early 20th century of iodine deficiency as the cause of endemic goiter1 many epidemiological studies were conducted in Italy...
January 12, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28078945/influences-of-population-size-and-density-on-birthplace-effects
#10
David J Hancock, Patrícia Coutinho, Jean Côté, Isabel Mesquita
Contextual influences on talent development (e.g., birthplace effects) have become a topic of interest for sport scientists. Birthplace effects occur when being born in a certain city size leads to participation or performance advantages, typically for those born in smaller or mid-sized cities. The purpose of this study was to investigate birthplace effects in Portuguese volleyball players by analysing city size, as well as population density - an important but infrequently used variable. Participants included 4062 volleyball players (Mage = 33), 53...
January 12, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28078832/pattern-of-clinical-benign-euthyroid-goitre-in-a-tertiary-care-center-in-the-central-province-of-sri-lanka-from-1981-2011
#11
P C Ratnatunga, R Dassanayaka, A N Kumari, A B Aglawatta, K B Galketiya, N V Ratnatunga
Objectives: To describe the pattern of clinical euthyroidgoitre in a tertiary care unit in Sri Lanka before and after iodination of salt in Sri Lanka. Methods: We reviewed our thirty-one year computerised database of patients with goitres, spanning iodination in 1995. Results: Prevalence of euthyroid clinical simple diffuse goitre did not reduce during the first thirteen years (p=0.822). However, it reduced in the latter four years from 2008 to 2011...
30, 2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/28078113/results-of-intraoperative-electron-beam-radiotherapy-containing-multimodality-treatment-for-locally-unresectable-t4-rectal-cancer-a-pooled-analysis-of-the-mayo-clinic-rochester-and-catharina-hospital-eindhoven
#12
Fabian A Holman, Michael G Haddock, Leonard L Gunderson, Miranda Kusters, Grard A P Nieuwenhuijzen, Hetty A van den Berg, Heidi Nelson, Harm J T Rutten
BACKGROUND: The aim of this study is to analyse the pooled results of intraoperative electron beam radiotherapy (IOERT) containing multimodality treatment of locally advanced T4 rectal cancer, initially unresectable for cure, from the Mayo Clinic, Rochester, USA (MCR) and Catharina Hospital, Eindhoven, The Netherlands (CHE), both major referral centers for locally advanced rectal cancer. A rectal tumor is called locally unresectable for cure if after full clinical work-up infiltration into the surrounding structures or organs has been demonstrated, which would result in positive surgical margins if resection was the initial component of treatment...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28068347/microbiologically-confirmed-tuberculosis-factors-associated-with-pre-treatment-loss-to-follow-up-and-time-to-treatment-initiation
#13
Judith Mwansa-Kambafwile, Boitumelo Maitshotlo, Andrew Black
BACKGROUND: The impact of new diagnostics on pre-treatment loss to follow up (Pre-treatment LTFU) has not been widely investigated. The reported rate of pre-treatment LTFU is however lower in studies where Xpert MTB/Rif (Xpert) has been used onsite as opposed to centrally. The use of the Xpert at point of care (POC) could have a role in reducing the pre-treatment LTFU rate among TB patients. We aimed to determine the pre-treatment LTFU rate and the time to treatment initiation as well as to describe associated factors in patients diagnosed with TB using POC Xpert or smear microscopy...
2017: PloS One
https://www.readbyqxmd.com/read/28057005/intragenerational-social-mobility-and-functional-somatic-symptoms-in-a-northern-swedish-context-analyses-of-diagonal-reference-models
#14
Frida Jonsson, Miguel San Sebastian, Anne Hammarström, Per E Gustafsson
BACKGROUND: Research indicate that social class mobility could be potentially important for health, but whether this is due to the movement itself or a result of people having been integrated in different class contexts is, to date, difficult to infer. In addition, although several theories suggest that transitions between classes in the social hierarchy can be stressful experiences, few studies have empirically examined whether such movements may have health effects, over and above the implications of "being" in these classes...
January 3, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28056954/estimating-direct-effects-of-parental-occupation-on-spaniards-health-by-birth-cohort
#15
Jaime Pinilla, Beatriz G Lopez-Valcarcel, Rosa M Urbanos-Garrido
BACKGROUND: Social health inequalities in adult population are partly due to socioeconomic circumstances in childhood. A better understanding of how those circumstances affect health during adulthood may improve the opportunities for reducing health disparities. The objective of this study is to investigate the effect of parental socioeconomic status, which is proxied by occupation, on adult Spaniards' health by birth cohort. The analysis will allow checking not only the direct impact of parental occupation on their offspring's health, but also whether inherited inequality has been reduced over time...
January 5, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28050759/tension-among-women-in-north-india-an-idiom-of-distress-and-a-cultural-syndrome
#16
Lesley Jo Weaver
The existing literature on Indian ethnopsychology has long asserted that somatization is a key aspect of experiences of distress. The study of idioms of distress arose out of work done in India (Nichter in Cult Med Psychiatry 5(4):379-408, 1981), but ironically, little subsequent work has systematically explored idioms of distress in this part of the world. This ethnographic study focused on the term tension (tenśan) and its relation to a cultural syndrome among women in urban North India. This syndrome appears to involve rapid-onset anger, irritation, rumination, and sleeplessness as key symptoms...
January 3, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/28043632/mycobacterial-coinfection-and-persisting-bovine-tuberculosis-has-the-time-arrived-for-a-policy-review
#17
Nader Mosavari, Morad Moradi Geravand, Keyvan Tadayon, Rohollah Keshavarz
OBJECTIVE/BACKGROUND: Bovine tuberculosis (BTb) is mainly a disease of cattle, although it continues to infect human populations across the world. Operation of a test and slaughter plan in Iran since 1981 has lowered the frequency of BTb from >5% to <0.14% at the national scale. In 2015, unusual uncontrollable epidemics of BTb were detected in two cattle farms in municipal suburbs of Qazvin and Isfahan. These farms had a tuberculin-test-certified record of BTb-free status for the past 5 consecutive years, with no new cattle registered with either of the two herds during this time period...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043250/-analysis-on-the-incidence-of-occupational-radiation-diseases-in-zhejiang-province-from-1981-to-2015
#18
A F Ye, Z Q Xuan, Q Y Ni
No abstract text is available yet for this article.
October 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28040406/35-years-of-experience-from-the-american-association-for-women-radiologists-increasing-the-visibility-of-women-in-radiology
#19
Lucy B Spalluto, Elizabeth K Arleo, Katarzyna J Macura, Carol M Rumack
Women radiologists remain in minority, unchanged for the past several decades. In 1981, the American Association for Women Radiologists (AAWR) was founded to address the problems that women radiologists were experiencing in being subordinate to male radiologists in the workplace and at the national level in organizations with respect to political power and financial compensation, as well as additional issues unique to women in radiology. The AAWR defined goals to meet the needs of women in radiology: improve the visibility of women radiologists, advance the professional and academic standing of women in radiology, and identify and address issues faced by women in radiology...
December 28, 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28034681/risks-of-second-malignancies-after-breast-cancer-treatment-long-term-results
#20
L Bazire, Y De Rycke, B Asselain, A Fourquet, Y M Kirova
PURPOSE: To estimate the long-term risk of second malignancies after breast cancer treatment in a large homogeneous cohort from a single institution. PATIENTS AND METHODS: All patients in this study were treated for non-metastatic breast cancer at the Curie institute, Paris, between 1981 and 2000. We calculated the cumulative incidence of second malignancies and the risk of developing each type of second malignancies over a period of 10 to 15 years. The observed crude incidence rates in the entire patient population were then compared to the expected incidence in the general population of French women, as provided by age-standardized data...
December 26, 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
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