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https://www.readbyqxmd.com/read/27909858/distribution-and-morphology-of-cholinergic-cells-in-the-branchial-epithelium-of-zebrafish-danio-rerio
#1
Peter C Zachar, Wen Pan, Michael G Jonz
Acetylcholine is an excitatory neurotransmitter important for oxygen sensing in mammals. A cholinergic mechanism in the fish gill has been implicated in the hyperventilatory response to acute hypoxia; however, the identity and distribution of acetylcholine-containing cells in the gills is poorly defined. We test the hypothesis that cholinergic cells are present in the gill filament epithelium in zebrafish (Danio rerio), a model vertebrate for which oxygen chemoreceptors are well characterized, and that these cells would receive nervous innervation...
December 2, 2016: Cell and Tissue Research
https://www.readbyqxmd.com/read/27907013/development-and-implementation-of-the-ebola-traveler-monitoring-program-and-clinical-outcomes-of-monitored-travelers-during-october-may-2015-minnesota
#2
Aaron DeVries, Pamela Talley, Kristin Sweet, Susan Kline, Patricia Stinchfield, Pritish Tosh, Richard Danila
BACKGROUND: In October 2014, the United States began actively monitoring all persons who had traveled from Guinea, Liberia, and Sierra Leone in the previous 21 days. State public health departments were responsible for monitoring all travelers; Minnesota has the largest Liberian population in the United States. The MDH Ebola Clinical Team (ECT) was established to assess travelers with symptoms of concern for Ebola virus disease (EVD), coordinate access to healthcare at appropriate facilities including Ebola Assessment and Treatment Units (EATU), and provide guidance to clinicians...
2016: PloS One
https://www.readbyqxmd.com/read/27906081/vacht-overexpression-increases-acetylcholine-at-the-synaptic-cleft-and-accelerates-aging-of-neuromuscular-junctions
#3
Satoshi Sugita, Leland L Fleming, Caleb Wood, Sydney K Vaughan, Matheus P S M Gomes, Wallace Camargo, Ligia A Naves, Vania F Prado, Marco A M Prado, Cristina Guatimosim, Gregorio Valdez
BACKGROUND: Cholinergic dysfunction occurs during aging and in a variety of diseases, including amyotrophic lateral sclerosis (ALS). However, it remains unknown whether changes in cholinergic transmission contributes to age- and disease-related degeneration of the motor system. Here we investigated the effect of moderately increasing levels of synaptic acetylcholine (ACh) on the neuromuscular junction (NMJ), muscle fibers, and motor neurons during development and aging and in a mouse model for amyotrophic lateral sclerosis (ALS)...
October 5, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27905541/serbian-language-version-of-the-modified-checklist-for-autism-in-toddlers-revised-with-follow-up-cross-cultural-adaptation-and-assessment-of-reliability
#4
Mia Carakovac, Jelena Jovanovic, Marko Kalanj, Nenad Rudic, Olivera Aleksic-Hil, Branko Aleksic, Itzel Bustos Villalobos, Hideki Kasuya, Norio Ozaki, Dusica Lecic-Tosevski, Milica Pejovic-Milovancevic
Early detection of Autism Spectrum Disorder (ASD) has proven to be of high significance, however there is a limited availability of ASD screening tools in Serbian language. In this study we aim to translate, assess reliability and, in part, test the applicability of Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT R/F) in Serbian Healthcare environment. We screened 128 children in three primary healthcare centres and 20 children in a tertiary psychiatric center, using M-CHAT R/F translated into Serbian language, between December 2014 and October 2015...
December 1, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27902890/sexual-behavior-and-sexually-transmitted-infections-among-swingers-results-from-an-online-survey-in-belgium
#5
Tom Platteau, Jacques van Lankveld, Lieselot Ooms, Eric Florence
Swingers are couples practicing consensual extradyadic heterosexual relations. This subculture is defined by venues, and online communities. This study aimed to assess swingers' lifestyle, sexual health, history of testing for sexually transmitted infections (STI), and review risk factors for sexual risk behavior and STI transmission. An online survey was distributed through venues, chat- and dating websites. Most of 480 swingers starting the survey completed it (n = 392, 81.6%). Women (n = 146) reported more frequent swinging (p = 0...
November 30, 2016: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/27886734/does-the-internet-affect-assortative-mating-evidence-from-the-u-s-and-germany
#6
Gina Potarca
The Internet has now become a habitual channel for finding a partner, but little is known about the impact of this recent partnership market on mate selection patterns. This study revisits the supply side perspective on assortative mating by exploring the role played by online venues in breeding educational, racial/ethnic and religious endogamy. It compares couples that met online (through either online dating platforms, Internet social networking, Internet gaming website, Internet chat, Internet community, etc...
January 2017: Social Science Research
https://www.readbyqxmd.com/read/27884324/postconditioning-with-sevoflurane-ameliorates-spatial-learning-and-memory-deficit-after-hemorrhage-shock-and-resuscitation-in-rats
#7
Xianwen Hu, Jingxian Wang, Qiquan Zhang, Xiaowen Duan, Zhiwu Chen, Ye Zhang
BACKGROUND: Severe hemorrhage shock and resuscitation are a systemic ischemia-reperfusion phenomenon which can induce learning and memory deficit in human and rats. Sevoflurane postconditioning has been proved to offer neuroprotection under different setting of cerebral ischemia-reperfusion in rats. The aim of this study was to investigate whether sevoflurane postconditioning could improve spatial learning and memory ability after hemorrhage shock and resuscitation in rats. METHODS: Thirty-five male rats were randomized into five groups: sham group, shock group, low concentration (sevo1, 1...
December 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27883997/cbt4bn-a-randomized-controlled-trial-of-online-chat-and-face-to-face-group-therapy-for-bulimia-nervosa
#8
Stephanie C Zerwas, Hunna J Watson, Sara M Hofmeier, Michele D Levine, Robert M Hamer, Ross D Crosby, Cristin D Runfola, Christine M Peat, Jennifer R Shapiro, Benjamin Zimmer, Markus Moessner, Hans Kordy, Marsha D Marcus, Cynthia M Bulik
OBJECTIVE: Although cognitive-behavioral therapy (CBT) represents the first-line evidence-based psychotherapy for bulimia nervosa (BN), most individuals seeking treatment do not have access to this specialized intervention. We compared an Internet-based manualized version of CBT group therapy for BN conducted via a therapeutic chat group (CBT4BN) to the same treatment conducted via a traditional face-to-face group therapy (CBTF2F). METHOD: In a two-site, randomized, controlled noninferiority trial, we tested the hypothesis that CBT4BN would not be inferior to CBTF2F...
November 25, 2016: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/27881576/exploring-men-s-perceptions-of-a-community-based-men-s-shed-programme-in-england
#9
Grant J McGeechan, C Richardson, L Wilson, G O'Neill, D Newbury-Birch
BACKGROUND: Sheds have been used in Australia for decades as an intervention to try and promote 'health by stealth' among men by providing a social space for those who may be particularly vulnerable to poor mental health. Little is known about the impact of men's sheds in England. METHODS: Members of 19 sheds from one local authority area were invited to participate in focus groups to explore their perceptions of their shed. In total, 32 men participated in five focus groups which were analysed using applied thematic analysis...
November 23, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27880781/assessment-of-blood-pressure-control-among-hypertensive-patients-in-southwest-ethiopia
#10
Solomon Woldegebriel Asgedom, Esayas Kebede Gudina, Tigestu Alemu Desse
BACKGROUND: The rate of blood pressure control among hypertensive patients is poor and the reasons for poor control of blood pressure remain poorly understood globally. OBJECTIVE: To assess the rate of blood pressure control among adult hypertensive patients at Jimma University Specialized Hospital. MATERIALS AND METHODS: We conducted a hospital based cross sectional study among adult hypertensive patients at Jimma University Specialized Hospital hypertension clinic from March 4, 2015 to April 3, 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27875066/sexuality-and-the-internet-a-study-of-the-perspectives-of-turkish-university-students
#11
Tuba Ucar, Zehra Golbasi, Ayten Senturk Erenel
The purpose of this study was to determine Turkish university students' uses of and attitudes toward the Internet concerning sexuality. The study was conducted in two public universities in the Central Anatolia and Eastern Anatolia regions of Turkey. Among the students invited to take part in the study, 1,330 students agreed to do so. The study data were collected using a questionnaire designed by researchers to determine participants' personal characteristics, computer and Internet uses in general, and for sexual matters...
November 22, 2016: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/27871887/a-silk-peptide-fraction-restores-cognitive-function-in-af64a-induced-alzheimer-disease-model-rats-by-increasing-expression-of-choline-acetyltransferase-gene
#12
Yeseul Cha, Sang Hoon Lee, Su Kil Jang, Haiyu Guo, Young-Hwan Ban, Dongsun Park, Gwi Yeong Jang, Sungho Yeon, Jeong-Yong Lee, Ehn-Kyoung Choi, Seong Soo Joo, Heon-Sang Jeong, Yun-Bae Kim
This study investigated the effects of a silk peptide fraction obtained by incubating silk proteins with Protease N and Neutrase (SP-NN) on cognitive dysfunction of Alzheimer disease model rats. In order to elucidate underlying mechanisms, the effect of SP-NN on the expression of choline acetyltransferase (ChAT) mRNA was assessed in F3.ChAT neural stem cells and Neuro2a neuroblastoma cells; active amino acid sequence was identified using HPLC-MS. The expression of ChAT mRNA in F3.ChAT cells increased by 3.79-fold of the control level by treatment with SP-NN fraction...
November 18, 2016: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/27866826/the-impact-of-online-therapeutic-feedback-on-outcome-measures-in-internet-cbti-for-adolescents-with-insomnia
#13
Eduard Jan de Bruin, Anne Marie Meijer
BACKGROUND: Guided Internet cognitive behavioral therapy for insomnia (CBTI) offers an effective treatment for adolescents, but little is known about the active ingredients of therapeutic feedback on outcomes. OBJECTIVE: This study aims to identify which factors can be distinguished in written therapeutic feedback in Internet CBTI, and examine whether these factors and participation in a chat session contribute to sleep outcomes. METHODS: Internet CBTI was applied to 57 adolescents (mean age 15...
September 13, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27866394/repeated-otilonium-bromide-administration-prevents-neurotransmitter-changes-in-colon-of-rats-underwent-to-wrap-restraint-stress
#14
Chiara Traini, Stefano Evangelista, Vincent Girod, Maria Simonetta Faussone-Pellegrini, Maria Giuliana Vannucchi
Otilonium bromide (OB) is a spasmolytic drug successfully used for the treatment of irritable bowel syndrome (IBS). Its efficacy has been attributed to the block of L- and T-type Ca(2+) channels and muscarinic and tachykinin receptors in the smooth muscle. Furthermore, in healthy rats, repeated OB administration modified neurotransmitter expression and function suggesting other mechanisms of action. On this basis, we investigated whether repeated OB treatment prevented the functional and neurochemical changes observed in the colon of rats underwent to wrap restrain stress (WRS) a psychosocial stressor considered suitable to reproduce the main IBS signs and symptoms...
November 20, 2016: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/27865908/oleic-acid-promotes-the-expression-of-neural-markers-in-differentiated-human-endometrial-stem-cells
#15
Maryam Ali Mohammadie Kojour, Somayeh Ebrahimi-Barough, Homa Mohseni Kouchesfehani, Hanieh Jalali, Mohammah Hosein Karbalaie Ebrahim
Variety of neurodegenerative diseases in humans are caused by loss of cells along with loss of function and disability. Cell replacement therapy is a potential strategy to cure neurodegenerative diseases. Mesenchymal stem cells are pluripotent non-hematopoietic cells that can be isolated from numerous tissues. Human endometrial-derived stem cell (hEnSC) are the abundant and easy available source with no immunological response, for cell replacement therapy. In the nervous system, where fatty acids are found in huge amounts, they participate in its development and maintenance throughout life...
November 16, 2016: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/27864939/gabaergic-innervation-of-the-ciliary-ganglion-in-macaque-monkeys-a-light-and-electron-microscopic-study
#16
Miriam Barnerssoi, Paul J May, Anja K E Horn
The vertebrate ciliary ganglion (CG) is a relay station in the parasympathetic pathway activating the iris sphincter and ciliary muscle to mediate pupillary constriction and lens accommodation, respectively. While the postganglionic motoneurons in the CG are cholinergic, as are their inputs, there is evidence from avian studies that GABA may also be involved. Here, we used light and electron microscopic methods to examine the GABAergic innervation of the CG in Macaca fascicularis monkeys. Immunohistochemistry for the gamma aminobutyric acid synthesizing enzyme glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) revealed that all CG neurons are contacted by ChAT-positive terminals...
November 16, 2016: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/27853512/contextual-hub-analysis-tool-chat-a-cytoscape-app-for-identifying-contextually-relevant-hubs-in-biological-networks
#17
Tanja Muetze, Ivan H Goenawan, Heather L Wiencko, Manuel Bernal-Llinares, Kenneth Bryan, David J Lynn
: Highly connected nodes (hubs) in biological networks are topologically important to the structure of the network and have also been shown to be preferentially associated with a range of phenotypes of interest. The relative importance of a hub node, however, can change depending on the biological context. Here, we report a Cytoscape app, the Contextual Hub Analysis Tool (CHAT), which enables users to easily construct and visualize a network of interactions from a gene list of interest, integrate contextual information, such as gene expression data, and identify hub nodes that are more highly connected to contextual nodes (e...
2016: F1000Research
https://www.readbyqxmd.com/read/27822877/feasibility-and-preliminary-efficacy-of-an-internet-support-group-for-parents-of-a-child-with-neurofibromatosis-type-1-a-pilot-study
#18
S Martin, M C Roderick, R Lockridge, M A Toledo-Tamula, A Baldwin, P Knight, P Wolters
This pilot study investigated the feasibility and preliminary efficacy of an Internet Support Group (ISG) for parents of children with NF1. Eligible parents were recruited by email and completed baseline questionnaires assessing social support, self-efficacy, depression, and anxiety. The ISG involved eight weekly 90-min chat sessions and a discussion forum open 24 h/day for 8 weeks. Follow-up measures were completed immediately post-intervention and 3 months later. Parents from 33 families (29 mothers, 4 fathers) completed baseline measures...
November 7, 2016: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27819483/the-effects-of-the-music-with-movement-intervention-on-the-cognitive-functions-of-people-with-moderate-dementia-a-randomized-controlled-trial
#19
Daphne Sze Ki Cheung, Claudia Kam Yuk Lai, Frances Kam Yuet Wong, Mason Chin Pang Leung
OBJECTIVE: The aim of this study was to examine the effects of the six-week music-with-movement (MM) intervention, as compared with music listening (ML) and social activity (SA), on the cognitive functions of people with moderate dementia over time. METHODS: A multi-center randomized controlled trial was conducted on 165 nursing home residents with moderate dementia. The MM intervention protocol was developed based on a critical literature review, and tested in three rounds of pilot studies before undergoing testing in this study...
November 7, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27817161/the-french-version-of-the-modified-checklist-for-autism-in-toddlers-m-chat-a-validation-study-on-a-french-sample-of-24-month-old-children
#20
Sophie Baduel, Quentin Guillon, Mohammad H Afzali, Nadège Foudon, Jeanne Kruck, Bernadette Rogé
Early ASD screening has the potential to reduce delays between initial parental concerns and diagnosis, and promote early intervention. The aim of this study was to validate the M-CHAT on a French population sample of 24 month-old children. This study included a low-risk sample of 1227 children. A total of 20 children screened positive on the M-CHAT. Twelve out of 20 of these children received a diagnosis of ASD at 36 months, yielding a PPV of 0.60. These results add to the evidence that the M-CHAT is a useful screening instrument and further demonstrates the importance of the follow-up interview in primary care settings...
November 5, 2016: Journal of Autism and Developmental Disorders
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