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raynaulds syndrome

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https://www.readbyqxmd.com/read/25500708/an-autoimmune-myositis-overlap-syndrome-associated-with-autoantibodies-to-nuclear-pore-complexes-description-and-long-term-follow-up-of-the-anti-nup-syndrome
#1
Jean-Luc Senécal, Catherine Isabelle, Marvin J Fritzler, Ira N Targoff, Rose Goldstein, Michel Gagné, Jean-Pierre Raynauld, France Joyal, Yves Troyanov, Marie-Christine Dabauvalle
Autoimmune myositis encompasses various myositis-overlap syndromes, each being identified by the presence of serum marker autoantibodies. We describe a novel myositis-overlap syndrome in 4 patients characterized by the presence of a unique immunologic marker, autoantibodies to nuclear pore complexes. The clinical phenotype was characterized by prominent myositis in association with erosive, anti-CCP, and rheumatoid factor-positive arthritis, trigeminal neuralgia, mild interstitial lung disease, Raynaud phenomenon, and weight loss...
November 2014: Medicine (Baltimore)
https://www.readbyqxmd.com/read/10403261/strong-association-of-autoantibodies-to-human-nuclear-lamin-b1-with-lupus-anticoagulant-antibodies-in-systemic-lupus-erythematosus
#2
J L Senécal, J Rauch, T Grodzicky, J P Raynauld, I Uthman, A Nava, M Guimond, Y Raymond
OBJECTIVE: To determine the frequency and clinical significance of high titers of IgG autoantibodies to nuclear lamin B1 in a large number of unselected and well-characterized systemic lupus erythematosus (SLE) patients, disease controls, and normal healthy controls. METHODS: A cross-sectional study of anti-lamin B1 autoantibodies, as measured by enzyme-linked immunosorbent assay using human recombinant lamin B1 autoantigen, was performed on serum samples obtained at first evaluation of 238 consecutive French Canadian adults: 61 healthy control subjects, 20 patients with osteoarthritis, 22 with ankylosing spondylitis, 11 with autoimmune hepatitis, 30 with rheumatoid arthritis, and 94 with SLE...
July 1999: Arthritis and Rheumatism
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