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Daniel Mulder

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https://www.readbyqxmd.com/read/29097266/direct-quantitative-measurement-of-the-kinetics-of-hla-specific-antibody-interactions-with-isolated-hla-proteins
#1
Sunil Daga, Harry Moyse, David Briggs, David Lowe, Neil Evans, James Jones, Rico Buchli, Curtis McMurtrey, Arend Mulder, William Hildebrand, Frans Claas, Robert Higgins, Daniel A Mitchell, Daniel Zehnder
HLA specific antibodies vary in their pathogenicity and this is likely to be the net effect of constant chain usage, quantity, specificity, and affinity. Here we have measured the affinity of human monoclonal antibodies for a range of HLA proteins. Purified antibodies and ligands allowed dynamic interactions to be measured directly by surface plasmon resonance. Physiochemical differences between pairs of ligands were quantified using electrostatic mismatch and hydrophobic mismatch scores. All antibodies were characterized by fast on-rates and slow off rates but with a wide range of association rates (kon, 3...
October 31, 2017: Human Immunology
https://www.readbyqxmd.com/read/29068511/multiple-hypotheses-explain-variation-in-extra-pair-paternity-at-different-levels-in-a-single-bird-family
#2
Lyanne Brouwer, Martijn van de Pol, Nataly Hidalgo Aranzamendi, Glen Bain, Daniel T Baldassarre, Lesley C Brooker, Michael G Brooker, Diane Colombelli-Négrel, Erik Enbody, Kurt Gielow, Michelle L Hall, Allison E Johnson, Jordan Karubian, Sjouke A Kingma, Sonia Kleindorfer, Marina Louter, Raoul A Mulder, Anne Peters, Stephen Pruett-Jones, Keith A Tarvin, Derrick J Thrasher, Claire W Varian-Ramos, Michael S Webster, Andrew Cockburn
Extra-pair paternity (EPP), where offspring are sired by a male other than the social male, varies enormously both within and among species. Trying to explain this variation has proved difficult because the majority of the interspecific variation is phylogenetically-based. Ideally, variation in EPP should be investigated in closely related species, but clades with sufficient variation are rare. We present a comprehensive multifactorial test to explain variation in EPP among individuals in 20 populations of nine species over 89 years from a single bird family (Maluridae)...
October 25, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28835363/the-metabolic-syndrome-and-risk-of-sudden-cardiac-death-the-atherosclerosis-risk-in-communities-study
#3
Paul L Hess, Hussein R Al-Khalidi, Daniel J Friedman, Hillary Mulder, Anna Kucharska-Newton, Wayne R Rosamond, Renato D Lopes, Bernard J Gersh, Daniel B Mark, Lesley H Curtis, Wendy S Post, Ronald J Prineas, Nona Sotoodehnia, Sana M Al-Khatib
BACKGROUND: Prior studies have demonstrated a link between the metabolic syndrome and increased risk of cardiovascular mortality. Whether the metabolic syndrome is associated with sudden cardiac death is uncertain. METHODS AND RESULTS: We characterized the relationship between sudden cardiac death and metabolic syndrome status among participants of the ARIC (Atherosclerosis Risk in Communities) Study (1987-2012) free of prevalent coronary heart disease or heart failure...
August 23, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28751965/four-simple-recommendations-to-encourage-best-practices-in-research-software
#4
Rafael C Jiménez, Mateusz Kuzak, Monther Alhamdoosh, Michelle Barker, Bérénice Batut, Mikael Borg, Salvador Capella-Gutierrez, Neil Chue Hong, Martin Cook, Manuel Corpas, Madison Flannery, Leyla Garcia, Josep Ll Gelpí, Simon Gladman, Carole Goble, Montserrat González Ferreiro, Alejandra Gonzalez-Beltran, Philippa C Griffin, Björn Grüning, Jonas Hagberg, Petr Holub, Rob Hooft, Jon Ison, Daniel S Katz, Brane Leskošek, Federico López Gómez, Luis J Oliveira, David Mellor, Rowland Mosbergen, Nicola Mulder, Yasset Perez-Riverol, Robert Pergl, Horst Pichler, Bernard Pope, Ferran Sanz, Maria V Schneider, Victoria Stodden, Radosław Suchecki, Radka Svobodová Vařeková, Harry-Anton Talvik, Ilian Todorov, Andrew Treloar, Sonika Tyagi, Maarten van Gompel, Daniel Vaughan, Allegra Via, Xiaochuan Wang, Nathan S Watson-Haigh, Steve Crouch
Scientific research relies on computer software, yet software is not always developed following practices that ensure its quality and sustainability. This manuscript does not aim to propose new software development best practices, but rather to provide simple recommendations that encourage the adoption of existing best practices. Software development best practices promote better quality software, and better quality software improves the reproducibility and reusability of research. These recommendations are designed around Open Source values, and provide practical suggestions that contribute to making research software and its source code more discoverable, reusable and transparent...
2017: F1000Research
https://www.readbyqxmd.com/read/28707452/on-the-dimensional-control-of-2%C3%A2-d-hybrid-nanomaterials
#5
Alessandro Longo, Dirk-Jan Mulder, Huub P C van Kuringen, Daniel Hermida-Merino, Dipanjan Banerjee, Debarshi Dasgupta, Irina K Shishmanova, Anne B Spoelstra, Dirk J Broer, Albert P H J Schenning, Giuseppe Portale
Thermotropic smectic liquid crystalline polymers were used as a scaffold to create organic/inorganic hybrid layered nanomaterials. Different polymers were prepared by photopolymerizing blends of a hydrogen bonded carboxylic acid derivative and a 10 % cross-linker of variable length in their liquid crystalline phase. Nanopores with dimensions close to 1 nm were generated by breaking the hydrogen bonded dimers in a high pH solution. The pores were filled with positively charged silver (Ag) ions, resulting in a layered silver(I)-polymeric hybrid material...
September 12, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28398520/injury-leads-to-the-appearance-of-cells-with-characteristics-of-both-microglia-and-astrocytes-in-mouse-and-human-brain
#6
Ulrika Wilhelmsson, Daniel Andersson, Yolanda de Pablo, Roy Pekny, Anders Ståhlberg, Jan Mulder, Nicholas Mitsios, Tibor Hortobágyi, Milos Pekny, Marcela Pekna
Microglia and astrocytes have been considered until now as cells with very distinct identities. Here, we assessed the heterogeneity within microglia/monocyte cell population in mouse hippocampus and determined their response to injury, by using single-cell gene expression profiling of cells isolated from uninjured and deafferented hippocampus. We found that in individual cells, microglial markers Cx3cr1, Aif1, Itgam, and Cd68 were co-expressed. Interestingly, injury led to the co-expression of the astrocyte marker Gfap in a subpopulation of Cx3cr1-expressing cells from both the injured and contralesional hippocampus...
June 1, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28214419/recommendations-for-gonadotoxicity-surveillance-in-male-childhood-adolescent-and-young-adult-cancer-survivors-a-report-from-the-international-late-effects-of-childhood-cancer-guideline-harmonization-group-in-collaboration-with-the-pancaresurfup-consortium
#7
REVIEW
Roderick Skinner, Renee L Mulder, Leontien C Kremer, Melissa M Hudson, Louis S Constine, Edit Bardi, Annelies Boekhout, Anja Borgmann-Staudt, Morven C Brown, Richard Cohn, Uta Dirksen, Alexsander Giwercman, Hiroyuki Ishiguro, Kirsi Jahnukainen, Lisa B Kenney, Jacqueline J Loonen, Lilian Meacham, Sebastian Neggers, Stephen Nussey, Cecilia Petersen, Margarett Shnorhavorian, Marry M van den Heuvel-Eibrink, Hanneke M van Santen, William H B Wallace, Daniel M Green
Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommendations vary considerably, causing uncertainty about optimum screening practices. This clinical practice guideline recommended by the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium, developed using evidence-based methodology, critically synthesises surveillance recommendations for gonadotoxicity in male childhood, adolescent, and young adult (CAYA) cancer survivors...
February 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28035926/pleiotropic-effect-of-human-apoe4-on-cerebral-ceramide-and-saturated-fatty-acid-levels
#8
Sandra den Hoedt, Carola I F Janssen, Giuseppe Astarita, Daniele Piomelli, Frank P J Leijten, Simone M Crivelli, Adrie J M Verhoeven, Helga E de Vries, Jochen Walter, Pilar Martinez-Martinez, Eric J G Sijbrands, Amanda J Kiliaan, Monique T Mulder
BACKGROUND: Apolipoprotein E (ApoE) is known for its role in lipid trafficking and the ɛ4 allele is a risk factor for late onset Alzheimer's disease (AD). Recently, aberrant ceramide and fatty acid (FA) levels have been implicated in AD. OBJECTIVE: To determine the specific effects of human ApoE4 (hE4) on cerebral ceramide and FA content during chow or a high fat/high cholesterol (HFHC) diet. METHODS: Cerebral ceramide and FA profiles were determined by LC-MSMS in 15-month-old female wild-type (WT), ApoE-knockout (E0), and hE4-knockin mice fed chow or a HFHC diet for 3 months...
December 30, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27485812/production-of-a-polar-fish-antimicrobial-peptide-in-escherichia-coli-using-an-elp-intein-tag
#9
Daniel A Sousa, Kelly C L Mulder, Kethly S Nobre, Nádia S Parachin, Octávio L Franco
An important aspect related to infectious pathogens is their exceptional adaptability in developing resistance, which leads to a perpetual challenge in the discovery of antimicrobial drugs with novel mechanisms of action. Among them, antimicrobial peptides (AMPs) stand out as promising anti-infective molecules. In order to overcome the high costs associated with isolation from natural sources or chemical synthesis of AMPs we propose the expression of Pa-MAP 2, a polyalanine AMP. Pa-MAP 2 was fused to an ELP-intein tag where the ELP (Elastin-like polypeptide) was used to promote aggregation and fast and cost-effective isolation after expression, and the intein was used to stimulate a controlled AMP release...
September 20, 2016: Journal of Biotechnology
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#10
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27218086/how-to-classify-plantar-plate-injuries-parameters-from-history-and-physical-examination
#11
Caio Nery, Michael Coughlin, Daniel Baumfeld, Fernando Raduan, Tania Szejnfeld Mann, Fernanda Catena
OBJECTIVE: To find the best clinical parameters for defining and classifying the degree of plantar plate injuries. METHOD: Sixty-eight patients (100 metatarsophalangeal joints) were classified in accordance with the Arthroscopic Anatomical Classification for plantar plate injuries and were divided into five groups (0 to IV). Their medical files were reviewed and the incidence of each parameter for the respective group was correlated. These parameters were: use of high heels, sports, acute pain, local edema, Mulder's sign, widening of the interdigital space, pain in the head of the corresponding metatarsal, touching the ground, "drawer test", toe grip and toe deformities (in the sagittal, coronal and transversal planes)...
November 2015: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/27175996/applying-evaluating-and-refining-bioinformatics-core-competencies-an-update-from-the-curriculum-task-force-of-iscb-s-education-committee
#12
Lonnie Welch, Cath Brooksbank, Russell Schwartz, Sarah L Morgan, Bruno Gaeta, Alastair M Kilpatrick, Daniel Mietchen, Benjamin L Moore, Nicola Mulder, Mark Pauley, William Pearson, Predrag Radivojac, Naomi Rosenberg, Anne Rosenwald, Gabriella Rustici, Tandy Warnow
No abstract text is available yet for this article.
May 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27058070/single-spin-asymmetries-from-a-single-wilson-loop
#13
Daniël Boer, Miguel G Echevarria, Piet J Mulders, Jian Zhou
We study the leading-power gluon transverse-momentum-dependent distributions (TMDs) of relevance to the study of asymmetries in the scattering off transversely polarized hadrons. Next-to-leading-order perturbative calculations of these TMDs show that at large transverse momentum they have common dynamical origins but that in the limit of a small longitudinal momentum fraction x, only one origin remains. We find that in this limit, only the dipole-type gluon TMDs survive and become identical to each other. At small x, they are all given by the expectation value of a single Wilson loop inside the transversely polarized hadron, the so-called spin-dependent odderon...
March 25, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/26810070/genetic-alterations-in-uncommon-low-grade-neuroepithelial-tumors-braf-fgfr1-and-myb-mutations-occur-at-high-frequency-and-align-with-morphology
#14
Ibrahim Qaddoumi, Wilda Orisme, Ji Wen, Teresa Santiago, Kirti Gupta, James D Dalton, Bo Tang, Kelly Haupfear, Chandanamali Punchihewa, John Easton, Heather Mulder, Kristy Boggs, Ying Shao, Michael Rusch, Jared Becksfort, Pankaj Gupta, Shuoguo Wang, Ryan P Lee, Daniel Brat, V Peter Collins, Sonika Dahiya, David George, William Konomos, Kathreena M Kurian, Kathryn McFadden, Luciano Neder Serafini, Hilary Nickols, Arie Perry, Sheila Shurtleff, Amar Gajjar, Fredrick A Boop, Paul D Klimo, Elaine R Mardis, Richard K Wilson, Suzanne J Baker, Jinghui Zhang, Gang Wu, James R Downing, Ruth G Tatevossian, David W Ellison
Low-grade neuroepithelial tumors (LGNTs) are diverse CNS tumors presenting in children and young adults, often with a history of epilepsy. While the genetic profiles of common LGNTs, such as the pilocytic astrocytoma and 'adult-type' diffuse gliomas, are largely established, those of uncommon LGNTs remain to be defined. In this study, we have used massively parallel sequencing and various targeted molecular genetic approaches to study alterations in 91 LGNTs, mostly from children but including young adult patients...
June 2016: Acta Neuropathologica
https://www.readbyqxmd.com/read/26643054/royal-australian-and-new-zealand-college-of-psychiatrists-clinical-practice-guidelines-for-mood-disorders
#15
REVIEW
Gin S Malhi, Darryl Bassett, Philip Boyce, Richard Bryant, Paul B Fitzgerald, Kristina Fritz, Malcolm Hopwood, Bill Lyndon, Roger Mulder, Greg Murray, Richard Porter, Ajeet B Singh
OBJECTIVES: To provide guidance for the management of mood disorders, based on scientific evidence supplemented by expert clinical consensus and formulate recommendations to maximise clinical salience and utility. METHODS: Articles and information sourced from search engines including PubMed and EMBASE, MEDLINE, PsycINFO and Google Scholar were supplemented by literature known to the mood disorders committee (MDC) (e.g., books, book chapters and government reports) and from published depression and bipolar disorder guidelines...
December 2015: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/26627985/h3abionet-a-sustainable-pan-african-bioinformatics-network-for-human-heredity-and-health-in-africa
#16
Nicola J Mulder, Ezekiel Adebiyi, Raouf Alami, Alia Benkahla, James Brandful, Seydou Doumbia, Dean Everett, Faisal M Fadlelmola, Fatima Gaboun, Simani Gaseitsiwe, Hassan Ghazal, Scott Hazelhurst, Winston Hide, Azeddine Ibrahimi, Yasmina Jaufeerally Fakim, C Victor Jongeneel, Fourie Joubert, Samar Kassim, Jonathan Kayondo, Judit Kumuthini, Sylvester Lyantagaye, Julie Makani, Ahmed Mansour Alzohairy, Daniel Masiga, Ahmed Moussa, Oyekanmi Nash, Odile Ouwe Missi Oukem-Boyer, Ellis Owusu-Dabo, Sumir Panji, Hugh Patterton, Fouzia Radouani, Khalid Sadki, Fouad Seghrouchni, Özlem Tastan Bishop, Nicki Tiffin, Nzovu Ulenga
The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping and sequencing technologies and improved data analysis capabilities. Some of the greatest genetic diversity among humans, animals, plants, and microbiota occurs in Africa, yet genomic research outputs from the continent are limited. The Human Heredity and Health in Africa (H3Africa) initiative was established to drive the development of genomic research for human health in Africa, and through recognition of the critical role of bioinformatics in this process, spurred the establishment of H3ABioNet, a pan-African bioinformatics network for H3Africa...
February 2016: Genome Research
https://www.readbyqxmd.com/read/26597956/the-effects-of-glp-1-analogues-in-obese-insulin-using-type-2-diabetes-in-relation-to-eating-behaviour
#17
MULTICENTER STUDY
Stefanie Amarens de Boer, Joop Daniel Lefrandt, Japke Frida Petersen, Hendrikus Hessel Boersma, Douwe Johannes Mulder, Klaas Hoogenberg
BACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1 RA) added to insulin in type 2 diabetes patients have shown to lower body weight, improve glycaemic control and reduce total daily insulin dose in short term studies, although the individual response greatly varies. OBJECTIVE: To evaluate GLP-1 RA treatment on body weight, glycaemic control and total daily insulin dose in obese, insulin-using type 2 diabetes patients after 2 years follow-up in a real life setting and to explore a possible relation with eating behaviour...
February 2016: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/26552515/leadership-in-mammalian-societies-emergence-distribution-power-and-payoff
#18
REVIEW
Jennifer E Smith, Sergey Gavrilets, Monique Borgerhoff Mulder, Paul L Hooper, Claire El Mouden, Daniel Nettle, Christoph Hauert, Kim Hill, Susan Perry, Anne E Pusey, Mark van Vugt, Eric Alden Smith
Leadership is an active area of research in both the biological and social sciences. This review provides a transdisciplinary synthesis of biological and social-science views of leadership from an evolutionary perspective, and examines patterns of leadership in a set of small-scale human and non-human mammalian societies. We review empirical and theoretical work on leadership in four domains: movement, food acquisition, within-group conflict mediation, and between-group interactions. We categorize patterns of variation in leadership in five dimensions: distribution (across individuals), emergence (achieved versus inherited), power, relative payoff to leadership, and generality (across domains)...
January 2016: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/26275916/near-complete-1h-13c-15n-resonance-assignments-of-dimethylsulfoxide-denatured-tgfbip-fas1-4-a546t
#19
Natalia V Kulminskaya, Yuichi Yoshimura, Kasper Runager, Charlotte S Sørensen, Morten Bjerring, Maria Andreasen, Daniel E Otzen, Jan J Enghild, Niels Chr Nielsen, Frans A A Mulder
The transforming growth factor beta induced protein (TGFBIp) is a major protein component of the human cornea. Mutations occurring in TGFBIp may cause corneal dystrophies, which ultimately lead to loss of vision. The majority of the disease-causing mutations are located in the C-terminal domain of TGFBIp, referred as the fourth fascilin-1 (FAS1-4) domain. In the present study the FAS1-4 Ala546Thr, a mutation that causes lattice corneal dystrophy, was investigated in dimethylsulfoxide using liquid-state NMR spectroscopy, to enable H/D exchange strategies for identification of the core formed in mature fibrils...
April 2016: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/26056966/the-care-of-adults-with-congenital-heart-disease-across-the-globe-current-assessment-and-future-perspective-a-position-statement-from-the-international-society-for-adult-congenital-heart-disease-isachd
#20
REVIEW
Gary Webb, Barbara J Mulder, Jamil Aboulhosn, Curt J Daniels, Maria Amalia Elizari, Gu Hong, Eric Horlick, Michael J Landzberg, Ariane J Marelli, Clare P O'Donnell, Erwin N Oechslin, Dorothy D Pearson, Els P G Pieper, Anita Saxena, Markus Schwerzmann, Karen K Stout, Carole A Warnes, Paul Khairy
The number of adults with congenital heart disease (CHD) has increased markedly over the past few decades as a result of astounding successes in pediatric cardiac care. Nevertheless, it is now well understood that CHD is not cured but palliated, such that life-long expert care is required to optimize outcomes. All countries in the world that experience improved survival in CHD must face new challenges inherent to the emergence of a growing and aging CHD population with changing needs and medical and psychosocial issues...
September 15, 2015: International Journal of Cardiology
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