keyword
https://read.qxmd.com/read/38169779/medical-management-to-treat-chronic-non-healing-ulcers-a-case-series
#1
JOURNAL ARTICLE
Joseph Jose, Bhanushree Soni, Saji Jose, Jose K Kokkatt
INTRODUCTION: Chronic non-healing leg ulcers are skin defects below the knee that resist healing for more than six weeks. They cause physical, emotional, and economic burdens to patients and society. OBJECTIVES: To introduce an innovative medical strategy that targets the chronic inflammation component in non-healing ulcers (NHUs) with rheumatic features and to evaluate its potential effectiveness in achieving complete healing. METHODS: We employed an empirical medical therapy regimen, which combined medications like deflazacort, colchicine, dapsone, hydroxychloroquine, and azathioprine...
January 2024: Curēus
https://read.qxmd.com/read/37865447/combined-management-of-wound-ulcers-with-focus-on-interventional-techniques
#2
JOURNAL ARTICLE
Teodora Bochnakova, Claire Kaufman
This review provides a summary of current practice patterns in managing venous ulcers. The authors will describe the workup for venous ulcers, including differentiation of symptoms, physical examination, and imaging to guide the most effective treatment course for each patient. An overview of conservative management and minimally invasive treatment options for venous ulcers will be provided with a specific focus on periulcer foam sclerotherapy to aid in preventing ulcer recurrence and promoting healing. We will give interventional troubleshooting techniques for challenging patient presentations...
June 2023: Techniques in Vascular and Interventional Radiology
https://read.qxmd.com/read/37711789/effectiveness-of-iliac-vein-stenting-combined-with-endovenous-laser-treatment-of-recurrent-varicose-veins-associated-with-iliac-vein-compression
#3
JOURNAL ARTICLE
Mingzhu Zeng, Biyun Teng, Yu Zhao, Fenghe Li, Xuehu Wang, Chuli Jiang, Wei Zhang, Zhi Xiang, Qiu Zeng
BACKGROUND: Iliac vein compression syndrome (IVCS) is an underlying cause of varicose vein (VV) recurrence after venous surgery. However, the management of recurrent varicose veins (RVVs) combined with IVCS has rarely been reported. This study aimed to investigate the outcomes of a one-stop procedure to correct outflow obstruction and superficial reflux for patients with RVVs and IVCS. METHODS: A retrospective analysis was conducted of 102 consecutive patients diagnosed with RVVs...
September 1, 2023: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/37647614/impact-of-lymphedema-in-the-management-of-venous-leg-ulcers
#4
JOURNAL ARTICLE
Tina Moon, Thomas F O'Donnell, Derek Weycker, Mark Iafrati
INTRODUCTION: Lymphedema (LED) in patients with venous leg ulcers (VLU) [VLU+LED] can impair ulcer healing and predispose to cellulitis. There is little data, however, demonstrating how lymphatic dysfunction may impact the clinical course, treatment, and healthcare expenditures for VLU+LED versus VLU-LED patients. OBJECTIVE: To determine how lymphatic dysfunction might influence treatment and expenditures among VLU patients in a large deidentified healthcare claims database...
August 30, 2023: Phlebology
https://read.qxmd.com/read/37592807/a-systematic-review-network-meta-analysis-and-meta-regression-on-surgical-and-endovenous-interventions-for-the-treatment-of-lower-limb-venous-ulcer-disease
#5
REVIEW
Vangelis Bontinis, Kiriakos Ktenidis, Alkis Bontinis, Andreas Koutsoumpelis, Constantine N Antonopoulos, Argirios Giannopoulos, Vasileios Rafailidis, Angeliki Chorti, Andrew W Bradbury
BACKGROUND: Venous leg ulcer (VLU) disease constitutes the most severe form of chronic venous insufficiency. We performed a network meta-analysis and meta-regression to investigate the efficacy and safety of the various available interventions in the treatment of VLU. METHODS: We conducted a systematic research corresponding to the instructions by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement for studies reporting on surgical or endovenous interventions for the treatment of VLU...
August 17, 2023: Journal of Endovascular Therapy
https://read.qxmd.com/read/37497816/endovenous-ablation-for-venous-leg-ulcers
#6
REVIEW
Paris L Cai, Louise H Hitchman, Abduraheem H Mohamed, George E Smith, Ian Chetter, Daniel Carradice
BACKGROUND: Venous leg ulcers (VLUs) are a serious manifestation of chronic venous disease affecting up to 3% of the adult population. This typically recalcitrant and recurring condition significantly impairs quality of life, and its treatment places a heavy financial burden upon healthcare systems. The longstanding mainstay treatment for VLUs is compression therapy. Surgical removal of incompetent veins reduces the risk of ulcer recurrence. However, open surgery is an unpopular option amongst people with VLU, and many people are unsuitable for it...
July 27, 2023: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/37422812/outcome-of-the-compression-dressing-for-two-days-vs-seven-days-after-varicose-vein-surgery
#7
JOURNAL ARTICLE
Aamir Khan, Naima Shakeel, Ahmad Rafique
BACKGROUND: Incompetence of the great saphenous vein (GSV) is a global issue and the most prevalent cause of chronic venous disease of the leg. Clinical manifestations range from moderate to severe, including tiredness, heaviness, and irritation, as well as hyperpigmentation and leg ulcers. Significant advancements in GSV ablation employing percutaneous methods, such as endovenous laser ablation, have been made in recent years. (EVLA). The objective of the study is to compare the outcome of the compression dressing for two days vs...
2023: Journal of Ayub Medical College, Abbottabad: JAMC
https://read.qxmd.com/read/37030444/early-results-following-comparison-of-radiofrequency-and-microfoam-ablation-of-large-diameter-truncal-veins-demonstrate-high-closure-rates-and-symptomatic-relief
#8
JOURNAL ARTICLE
Amanda L Chin, Stephanie D Talutis, Peter F Lawrence, Juan Carlos Jimenez
OBJECTIVE: Endovenous closure of truncal veins with a large diameter (LD) (≥8 mm) has been associated with higher risk of post ablation thrombus propagation into the deep venous system. Similar findings after Varithena microfoam ablation (MFA) have not been characterized. The study objective was to analyze outcomes after both radiofrequency ablation (RFA) and MFA and of LD truncal veins. METHODS: A retrospective review of a prospectively maintained database was performed...
July 2023: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/36972751/view-vlu-observational-study-of-the-effect-of-varithena-on-wound-healing-in-the-treatment-of-venous-leg-ulcers
#9
JOURNAL ARTICLE
Michael Y Shao, Stuart Harlin, Beverly Chan, KathyLee Santangelo, Eri Fukaya, Julianne Stoughton, Raghu Kolluri
OBJECTIVES: Chronic venous hypertension, triggered by venous reflux and/or obstruction, leads to skin changes and venous leg ulcers. Compression therapy is standard of care, but many wounds remain unhealed. The objectives of this study were to observe the effects of endovenous chemical ablation with commercially available 1% polidocanol injectable microfoam on venous leg ulcer healing and recurrence rates. METHODS: The VIEW VLU study was a multicenter, open-label, Phase 4 registry of patients with active venous leg ulcers resulting from venous insufficiency of the great saphenous vein and/or anterior accessory saphenous vein systems who underwent ablation with 1% polidocanol microfoam...
March 25, 2023: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/36897618/use-of-advanced-elastomeric-skin-protectant-on-venous-leg-ulcer-periwound-skin
#10
JOURNAL ARTICLE
Emily Greenstein
INTRODUCTION: VLUs are associated with prolonged wound healing, high recurrence rates, and fragile periwound skin. OBJECTIVE: Skin protectant use with wound dressings and multilayer compression wraps was examined. METHODS: Deidentified retrospective patient data were assessed. Patients received endovenous ablation, followed by application of zinc barrier cream to periwound skin before wound dressing and multilayer compression wrap use. Dressings were changed every 7 days, and zinc barrier cream reapplied...
February 2023: Wounds: a Compendium of Clinical Research and Practice
https://read.qxmd.com/read/36751227/effect-of-endovenous-laser-ablation-along-with-compression-therapy-on-chronic-venous-ulcer-healing
#11
JOURNAL ARTICLE
Sheetal Uttaray, Venkata Vineeth Vaddavalli, Ajay Savlania, Arunanshu Behera, Lileswar Kaman, Ujjwal Gorsi
Introduction Chronic venous insufficiency is a major cause of morbidity, and there is a paucity of data regarding its epidemiology due to the lack of a central wound registry. In this study, we aimed to study the time for healing of the ulcer and compliance with compression therapy (CT) following endovenous laser ablation (EVLA) ± ultrasound-guided foam sclerotherapy (UGFS) along with CT in patients with chronic venous ulcers. Methods This prospective observational study was conducted from January 2020 to June 2021 after obtaining institutional ethical committee clearance...
January 2023: Curēus
https://read.qxmd.com/read/36685771/national-trend-of-the-treatment-for-chronic-venous-diseases-in-korea-between-2010-and-2020
#12
JOURNAL ARTICLE
SooBum Shon, Hyangkyoung Kim, Hyeong Cheol Kim, Sungsin Cho, Seung Hwan Lee, Jin Hyun Joh
PURPOSE: Limited data are available on the nationwide trend of treatments for chronic venous disease (CVD). The aim of the present study was to identify the nationwide trends of CVD treatments in Korea. METHODS: A serial, cross-sectional study was conducted with the use of time trends to analyze patients with CVD between 2010 and 2020. The trends in the number of patients and procedures were analyzed including sclerotherapy, open surgery, and endovenous thermal ablation (ETA)...
January 2023: Annals of Surgical Treatment and Research
https://read.qxmd.com/read/36542379/cost-effectiveness-of-compression-therapy-with-early-endovenous-ablation-in-venous-ulceration-for-a-medicare-population
#13
JOURNAL ARTICLE
Hanke Zheng, Gregory A Magee, Tze-Woei Tan, David G Armstrong, William V Padula
IMPORTANCE: Venous leg ulcers (VLU) are the most common cause of lower extremity ulceration that commonly occur among older individuals and are characterized by a slow healing trajectory and frequent recurrence; in the United States, VLUs affect more than 600 000 people per year with an estimated cost of $3.5 billion. Clinical trial data show that early intervention with endovenous ablation substantially improves the healing rate and reduces recurrence among patients with VLUs, but there is a need to assess the cost-effectiveness of early endovenous ablation in the US context...
December 1, 2022: JAMA Network Open
https://read.qxmd.com/read/36063058/efficiency-of-endovenous-laser-and-glue-ablation-methods-in-comparison-with-conventional-surgery-for-the-treatment-of-venous-ulcers
#14
JOURNAL ARTICLE
Ibrahim Erdinc
INTRODUCTION: In this study, we aimed to investigate the efficiency of endovenous laser and glue ablation techniques and compared the results with conventional surgical stripping. PATIENTS AND METHODS: Between January 2005 and January 2020, among 3133 consecutive patients with superficial venous reflux disease receiving treatment at our institution, there were 112 consecutive patients with active venous ulcers. Patients were divided into 3 groups as receiving conventional open surgical treatment (Group 1, n : 70), endovenous glue ablation (Group 2, n : 20), and endovenous laser ablation (Group 3, n : 22)...
October 2022: Phlebology
https://read.qxmd.com/read/35961629/factors-associated-with-delayed-venous-ulcer-healing-after-endovenous-intervention-for-superficial-venous-insufficiency
#15
JOURNAL ARTICLE
Toni Pihlaja, Laura-Maria Vanttila, Pasi Ohtonen, Matti Pokela
OBJECTIVE: This retrospective trial analyzed the effect of predetermined variables on venous ulcer healing after endovenous ablation of insufficient veins. METHODS: A total of 259 patients presenting 273 venous leg ulcers (VLUs) at Oulu University Hospital vascular outpatient clinic between January 2010 and December 2020 were included in the study. In addition to compression therapy, all patients received endovenous ablation (endothermal ablation and/or foam sclerotherapy) to promote venous healing...
November 2022: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/35689289/axial-ablation-versus-terminal-interruption-of-the-reflux-source-aavtirs-a-randomised-controlled-trial
#16
RANDOMIZED CONTROLLED TRIAL
C R Keohane, D Westby, M Twyford, T Ahern, W Tawfick, S R Walsh
BACKGROUND: Treatment of superficial venous reflux has been shown to improve ulcer healing time and reduce the risk of ulcer recurrence. Terminal ablation of the reflux source (TIRS) is an alternative to formal endovenous ablation or surgery which can be performed by injecting sclerosant foam into the peri-ulcer plexus of the veins. TIRS has been shown to be successful and in our experience is the option preferred by many patients, when offered as an alternative to axial ablation (AA)...
June 10, 2022: Trials
https://read.qxmd.com/read/35490951/clinical-outcomes-of-different-endovenous-procedures-among-patients-with-varicose-veins-and-iliac-vein-compression-a-retrospective-cohort-study
#17
MULTICENTER STUDY
Yang Han, Ye Tian, Lu Gao, Jingdong Tang, Pengcheng Fan, Longlong Cong, Jian Dong, Lin Yang
OBJECTIVE: This study aimed to investigate the short-term outcomes of three endovenous procedures in patients with varicose veins (VVs) and severe iliac vein compression syndrome (IVCS). METHODS: A total of 158 consecutive patients were included in this multicenter retrospective study from May 2017 to December 2019; 54 patients underwent endovenous laser ablation (EVLA) alone, 47 patients underwent EVLA and balloon angioplasty (BA), and 57 patients underwent EVLA and stenting angioplasty (SA)...
May 2022: International Journal of Surgery
https://read.qxmd.com/read/35472495/a-contemporary-comparison-of-cyanoacrylate-radiofrequency-and-endovenous-laser-ablation-on-healing-of-active-venous-ulceration
#18
COMPARATIVE STUDY
Lindsey Korepta, Matthew Ward, Matthew Blecha, James Sinacore, Bernadette Aulivola
BACKGROUND: The goal of this study is to compare the healing rates of active lower extremity venous ulcers for patients receiving one of 3 ablation methods, compare their complications, and identify factors affecting successful healing and prevention of recurrence. METHODS: For this study, data were collected retrospectively on 146 patients at a single institution, tertiary referral center, with an active venous ulcer who underwent ablation therapy via cyanoacrylate (VenaSeal), radiofrequency (RFA), or endovenous laser ablation (EVLA) from 2010 to 2020...
November 2022: Annals of Vascular Surgery
https://read.qxmd.com/read/35452407/a-strategy-to-enable-rapid-healing-and-prevent-recurrence-of-venous-ulcers
#19
JOURNAL ARTICLE
Kenji Yamamoto, Senri Miwa, Tomoyuki Yamada, Shuji Setozaki, Mamoru Hamuro, Shunji Kurokawa, Sakae Enomoto
INTRODUCTION: Venous ulcers are often intractable. OBJECTIVE: The aim of this study was to retrospectively analyze the effectiveness of endovenous ablation, compression therapy, moist wound healing, and skin care in the management of venous ulcers. MATERIALS AND METHODS: Twenty-eight consecutive patients (10 male, 18 female; mean age, 70.1 years) with Clinical-Etiology-Anatomy-Pathophysiology (CEAP) class C6 venous ulcer underwent endovenous ablation between December 2014 and August 2020...
April 2022: Wounds: a Compendium of Clinical Research and Practice
https://read.qxmd.com/read/35418769/current-best-practice-in-the-management-of-varicose-veins
#20
REVIEW
Mark Steven Whiteley
This article outlines the current best practice in the management of varicose veins. "Varicose veins" traditionally means bulging veins, usually seen on the legs, when standing. It is now a general term used to describe these bulging veins, and also underlying incompetent veins that reflux and cause the surface varicose veins. Importantly, "varicose veins" is often used for superficial venous reflux even in the absence of visible bulging veins. These can be simply called "hidden varicose veins". Varicose veins usually deteriorate, progressing to discomfort, swollen ankles, skin damage, leg ulcers, superficial venous thrombosis and venous bleeds...
2022: Clinical, Cosmetic and Investigational Dermatology
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