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josef parnas

Yoshiaki Motobayashi, Josef Parnas, Yoshiaki Motobayashi, Bin Kimura, Dylan Luers Toda
No abstract text is available yet for this article.
July 29, 2016: History of Psychiatry
Julie Nordgaard, Kasper Jessen, Ditte Sæbye, Josef Parnas
AIMS: To explore whether the diagnostic homogeneity in a daily, routine clinical activity changed visibly over two historical periods (the ICD-8 and the ICD-10 era) across and within five psychiatric in-patient clinics. METHODS: In this register study, we analyzed the discharge diagnoses from five university-affiliated departments of psychiatry in Denmark in two time periods: 1980-1985 (ICD-8) and 2001-2010 (ICD-10). RESULTS: The synchronic inter-departmental diagnostic differences did not decrease in the ICD-10 era compared with ICD-8 era...
September 2016: Social Psychiatry and Psychiatric Epidemiology
Josef Parnas, Mads Gram Henriksen
No abstract text is available yet for this article.
June 2016: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Josef Parnas, Mads Gram Henriksen
Mysticism and schizophrenia are different categories of human existence and experience. Nonetheless, they exhibit important phenomenological affinities, which, however, remain largely unaddressed. In this study, we explore structural analogies between key features of mysticism and major clinical-phenomenological aspects of the schizophrenia spectrum disorders-i.e. attitudes, the nature of experience, and the 'other', mystical or psychotic reality. Not only do these features gravitate around the issue of the basic dimensions of consciousness, they crucially seem to implicate and presuppose a specific alteration of the very structure of consciousness...
July 2016: Consciousness and Cognition
Danny Koren, Liza Lacoua, Lily Rothschild-Yakar, Josef Parnas
BACKGROUND AND GOAL: Recent findings have provided preliminary support for the notion that basic self-disturbances (SD) are related to prodromal symptoms among nonpsychotic help-seeking adolescents. As a sizable proportion of adolescents who are at risk do not seek help, this study attempts to assess the extent to which these findings can be generalized to the entire population of adolescents who are at risk for psychosis. METHOD: The concurrent relationship between SD and prodromal symptoms was explored in a sample of 100 non-help-seeking adolescents (age 13-15) from the community...
September 2016: Schizophrenia Bulletin
Elizabeth Barry
This article will explore the representation of certain mental and somatic phenomena in Beckett's trilogy of novels Molloy, Malone Dies and The Unnamable, exploring how his understanding of schizophrenia and psychosis informs his representation of the relationship between mind and body. It will also examine recent phenomenological and philosophical accounts of schizophrenia (Louis Sass, Josef Parnas, Shaun Gallagher) that see the condition as a disorder of selfhood and concentrate in it on the disruption to ipseity, a fundamental and pre-reflective awareness of self that leads to a loss of 'grip' (in the term of Merleau-Ponty) on concepts and percepts...
June 2016: Journal of Medical Humanities
Lisa Maria Dersch, Veronique Beckers, Detlev Rasch, Guido Melzer, Christoph Bolten, Katina Kiep, Horst Becker, Oliver Ernst Bläsing, Regine Fuchs, Thomas Ehrhardt, Christoph Wittmann
Here, we demonstrate whole-plant metabolic profiling by stable isotope labeling and combustion isotope-ratio mass spectrometry for precise quantification of assimilation, translocation, and molecular reallocation of (13)CO2 and (15)NH4NO3 The technology was applied to rice (Oryza sativa) plants at different growth stages. For adult plants, (13)CO2 labeling revealed enhanced carbon assimilation of the flag leaf from flowering to late grain-filling stage, linked to efficient translocation into the panicle. Simultaneous (13)CO2 and (15)NH4NO3 labeling with hydroponically grown seedlings was used to quantify the relative distribution of carbon and nitrogen...
May 2016: Plant Physiology
Josef Parnas
No abstract text is available yet for this article.
October 2015: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Michael Kyrios, Barnaby Nelson, Claire Ahern, Thomas Fuchs, Josef Parnas
No abstract text is available yet for this article.
2015: Psychopathology
Andreas Rosén Rasmussen, Josef Parnas
Vivid mental imagery occurs frequently in schizophrenia spectrum disorders (SSDs). Overlapping phenomena, such as obsessions or ruminations, are also frequent in other psychiatric disorders, raising significant diagnostic challenges. Unfortunately, contemporary operational psychopathology lacks the epistemological and phenomenological framework to address such questions. Using the resources of phenomenology and philosophy of mind, we articulate the structure of imagination and describe its distinctive modifications in the SSDs...
2015: Psychopathology
Josef Parnas, Lennart B Jansson
The release of DSM-5 and the preparations for the launch of the ICD-11 provoked a series of critiques of psychiatric classification, which continues to depend largely on clinical description. Among the immediate problems are those of arbitrary diagnostic thresholds, tendency to reification, rigid category boundaries, comorbidity, diagnostic 'epidemics' and differential diagnostic dilemmas. We argue that many of those problems stem from the polythetic-operational definitions of psychiatric categories, which thereby come to lack an organizing prototype-directed or gestaltic intelligibility principle...
2015: Psychopathology
Josef Parnas
No abstract text is available yet for this article.
June 2015: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Sidse M Arnfred, Andrea Raballo, Morten Morup, Josef Parnas
BACKGROUND: Anomalies of self-awareness (self-disorders, SDs) are theorized to be basic to schizophrenia psychopathology. We have previously observed dysfunction of brain processing of proprioception in schizophrenia spectrum disorders (SZS). We hypothesized that SDs could be associated with abnormalities of early contralateral proprioceptive evoked oscillatory brain activity. METHODS: We investigated the association between proprioceptive evoked potential components and SDs in a re-analysis of data from a subsample (n = 12) of SZS patients who had previously been observed with deviant proprioceptive evoked potentials and interviewed with the Examination of Anomalous Self-Experience (EASE) scale...
2015: Psychopathology
Josef Parnas, Mads Gram Henriksen
This article explores the phenomenological and empirical rediscovery of anomalous self-experience as a core feature of the schizophrenia spectrum disorders and presents the current status of research in this field. Historically, a disordered self was considered to be a constitutive phenotype of schizophrenia. Although the notion of a disordered self has continued to appear occasionally over the years-mainly in the phenomenologically or psychodynamically oriented literature-this notion was usually considered as a theoretical construct rather than as referring to concretely lived anomalous experiences...
September 2014: Harvard Review of Psychiatry
Josef Parnas, John Carter, Julie Nordgaard
AIM: The notion of a disordered self as a core disturbance of schizophrenia was proposed in many foundational texts. Recent studies, spurred by the development of the Examination of Anomalous Self-Experience (EASE), seem to indicate that self-disorders are a specific manifestation of schizophrenia vulnerability. Follow-up studies of help-seeking, prodromal and first-admission patients have demonstrated the utility of self-disorders for predicting later schizophrenia-spectrum disturbance...
February 2016: Early Intervention in Psychiatry
Barnaby Nelson, Josef Parnas, Louis A Sass
No abstract text is available yet for this article.
May 2014: Schizophrenia Bulletin
Josef Parnas
No abstract text is available yet for this article.
February 2014: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Julie Nordgaard, Josef Parnas
INTRODUCTION: Self-disorders (SD) have been described as a core feature of schizophrenia both in classical and recent psychopathological literature. However, the specificity of SD for the schizophrenia spectrum disorders has never been demonstrated in a diagnostically heterogeneous sample, nor has the concurrent validity of SD been examined. AIM: (1) To examine the specificity of Examination of Anomalous Self-Experiences (EASE) measured SD to the schizophrenia spectrum disorder in first contact inpatients, (2) to explore the internal consistency and factorial structure of the EASE, (3) to assess the concurrent validity of SD by exploring correlations between SD and the canonical psychopathological dimensions of schizophrenia, (4) to explore relations of SD to intelligence, sociodemographic, and extrinsic illness characteristics...
November 2014: Schizophrenia Bulletin
Josef Parnas, Mads Gram Henriksen
Psychiatry is in a time of crisis. The absence of significant breakthroughs to actionable etiological knowledge has left the discipline in a state of uncertainty and worries are being voiced about its status and future. In our view, the stagnation can be, at least in part, ascribed to an excessive, behaviorist-oriented, epistemological, and ontological simplification of psychopathology. The aim of this phenomenological study is to articulate the notion of the 'disordered self' in schizophrenia, a notion that we believe constitutes an important step forward in grasping its essential pathogenetic structures...
2013: Psychopathology
Mads G Henriksen, Josef Parnas
Poor insight into illness is considered the primary cause of treatment noncompliance in schizophrenia. In this article, we critically discuss the predominant conceptual accounts of poor insight, which consider it as an ineffective self-reflection, caused either by psychological defenses or impaired metacognition. We argue that these accounts are at odds with the phenomenology of schizophrenia, and we propose a novel account of poor insight. We suggest that the reason why schizophrenia patients have no or only partial insight and consequently do not comply with treatment is rooted in the nature of their anomalous self-experiences (ie, self- disorders) and the related articulation of their psychotic symptoms...
May 2014: Schizophrenia Bulletin
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