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Shakil Ahmed Nagori, Anson Jose, Venkatesan Gopalakrishnan, Indranil Deb Roy, Probodh K Chattopadhyay, Ajoy Roychoudhury
OBJECTIVE: The aim of the systematic review was to analyse the available evidence in order to assess the efficacy of dextrose prolotherapy in improving outcomes in temporomandibular joint (TMJ) hypermobility patients as compared to placebo. METHODS: An electronic search of PubMed, Scopus, CENTRAL and Google scholar databases was performed for English language papers published up to February 2018. Randomised clinical trials (RCTs) and controlled clinical trials (CCTs) comparing dextrose prolotherapy with placebo for TMJ hypermobility were included...
July 19, 2018: Journal of Oral Rehabilitation
Richard J van Arkel, K C Geoffrey Ng, Sarah K Muirhead-Allwood, Jonathan R T Jeffers
BACKGROUND: The hip joint capsule passively restrains extreme range of motion, protecting the native hip against impingement, dislocation, and edge-loading. We hypothesized that following total hip arthroplasty (THA), the reduced femoral head size impairs this protective biomechanical function. METHODS: In cadavers, THA was performed through the acetabular medial wall, preserving the entire capsule, and avoiding the targeting of a particular surgical approach. Eight hips were examined...
July 18, 2018: Journal of Bone and Joint Surgery. American Volume
Tomoaki Kamiya, Tomoyuki Suzuki, Hidenori Otsubo, Miki Kuroda, Takashi Matsumura, Chihiro Kubota, Toshihiko Yamashita
BACKGROUND: Hypermobile lateral meniscus (HLM) is one of the causes of knee pain and a locking sensation. It is thought that disruption of the popliteomeniscle fascicles lead to hypermobility of the lateral meniscus in adults. In cases of HLM, the posterior portion of the lateral meniscus shows forward abnormal translation with knee flexion and backward translation with knee extension. We refer to this phenomenon as paradoxical motion. The purpose of this study was to report an arthroscopic HLM stabilization and evaluate the midterm clinical outcomes...
July 13, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Gadi Revivo, Diane K Amstutz, Christine M Gagnon, Zachary L McCormick
BACKGROUND: The relationship between chronic musculoskeletal pain and joint hypermobility in a small percentage of the pediatric population is well described. However, literature discussing the treatment of chronic pain associated with joint hypermobility in pediatrics is limited. The present study examines the impact of interdisciplinary treatment on chronic pain in pediatrics with joint hypermobility syndrome (JHS). OBJECTIVE: To determine if pediatric patients with chronic pain related to joint hypermobility can be effectively treated with an intensive, interdisciplinary pain management program, as measured by changes in pain, psychosocial and physical functioning, as well as parental coping...
July 13, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
Bernardita Suárez, Andrés Lozano-Arango, Diego Araneda, Fanny Cortés, Cecilia Hervias, Giancarlo Calcagno, Ximena Ortega, Claudia Castiglioni
Myopathies secondary to collagen VI mutations (COLVI-M) are the most frequent in the northern hemisphere, affecting the adult and pediatric population. There are no data on its prevalence in Latin America. They are characterized by a great clinical variability, from severe phenotypes, such as Ullrich congenital muscular dystrophy (UCMD), to intermediate and mild ones such as Bethlem myopathy (BM). Its onset is also variable and extends from the neonatal period to adulthood. Given the presence of joint hypermobility, the differential diagnosis should be made with various connective tissue diseases...
June 2018: Revista Chilena de Pediatría
Rene Burchard, Robin Massa, Christian Soost, Wolfgang Richter, Gerhard Dietrich, Arne Ohrndorf, Hans-Jürgen Christ, Claus-Peter Fritzen, Jan Adriaan Graw, Jan Schmitt
BACKGROUND: Hallux valgus disease is a common deformity of the forefoot. There are currently more than 100 surgical approaches for operative treatment. Because hypermobility of the first tarsometatarsal joint is considered to be causal for hallux valgus disease, fusion of the tarsometatarsal joint is an upcoming surgical procedure. Despite the development of new and increasingly stable fixation devices like different locking plates, malunion rates have been reported in 5 to 15% of cases...
July 11, 2018: Journal of Orthopaedic Surgery and Research
Leandro Arribillaga, Rubén Guillermo Bengió, Marta Ledesma, Ariel Montedoro, Sergio Orellana, Florencia Pisano, Ruben Hugo Bengió
INTRODUCTION: Various authors argued that the voiding urgency component in mixed urinary incontinence (MUI) is different than urge urinary incontinence (UUI). In this last case they suggest that incontinence in MUI could be overdiagnosed in patients with SUI, misunderstanding the leak as UUI. OBJETIVES: To evaluate clinical and urodynamic characteristics of patients with MUI and pure UUI. METHODS: A retrospective study of our urodynamics database was performed evaluating 450 women with MUI and UUI...
July 2018: Archivos Españoles de Urología
Louise C Mcloughlin, M Gleeson, S Francis, C O'rourke, H D Flood
INTRODUCTION: Pubo-vaginal sling placed at the bladder neck has been the gold standard treatment for stress urinary incontinence (SUI). The synthetic midurethral sling (MUS) is now widely used, as morbidity rates with this technique are substantially reduced. This is an initial report on long-term outcomes of a polypropylene sling (PPS) placed in the traditional bladder neck location. METHODS: A retrospective analysis of all patients who underwent PPS insertion at our institution between 2006 and 2014 was conducted...
June 8, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Ivan Adamec, Anamari Junakovic, Magdalena Krbot Skorić, Mario Habek
AIM: The aim of this study was to investigate the association of autonomic nervous system abnormalities on head-up tilt table test (HUTT) with generalized joint hypermobility, expressed by Beighton score (BS). METHODS: This was a prospective study that included 115 consecutive patients (91 females; mean age 34.35 ± 14.11) referred either for the HUTT or testing of the cardiovascular autonomic reflexes together with HUTT. Generalized joint hypermobility was evaluated according to the BS system after which HUTT was performed...
July 9, 2018: European Neurology
Pierrick Henneton, Anne Legrand, Cecilia Giunta, Michael Frank
Pathogenic variants in the lysyl-hydroxylase-1 gene (PLOD1) are responsible for the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS). The disease is classically responsible for severe hypotonia at birth, progressive kyphoscoliosis, generalised joint hypermobility and scleral fragility. Arterial fragility is an important feature of the disease, but its characterisation remains limited. We report the clinical history of a 41-year-old woman who presented repeated arterial accidents, which occurred in previously normal medium size arteries within a limited time span of 2 years...
July 6, 2018: BMJ Case Reports
Veria Vacchiano, Nicola Frattaruolo, Luca Mancinelli, Matteo Foschi, Antonio Carotenuto, Cinzia Scandellari, Maurizio Piattelli, Vincenzo Brescia Morra, Alessandra Lugaresi
BACKGROUND: Teriflunomide is a once-daily oral immunomodulator approved for the treatment of relapsing-remitting multiple sclerosis (RRMS) with a consistent safety profile in clinical trials. We report three cases of multiple teeth loss during teriflunomide treatment. CASE REPORTS: Case 1: a 39 year-old woman started teriflunomide for RRMS, switching from interferon beta. Four months later she complained about mandibular pain followed by the sudden loss of 4 teeth, in the absence of bleeding or trauma...
June 30, 2018: Multiple Sclerosis and related Disorders
Yves Y Palad, Andrew M Leaver, Marnee J McKay, Jennifer N Baldwin, Frances Rom M Lunar, Faith Deanne Mari Caube, Joshua Burns, Milena Simic
OBJECTIVE: To report the prevalence of varus thrust and normative values for hip-knee-ankle (HKA) angle deviation across the lifespan, and to explore associations between HKA angle deviation and selected clinical factors. DESIGN: This was a cross-sectional observational study of 572 participants from the 1000 Norms Project, aged 3-101 years and who self-reported as being healthy. Video recordings (2D) of frontal plane gait were reviewed by physiotherapists for presence of knee thrust and quantification of HKA angle deviation (the difference between HKA angle at initial contact and mid-stance)...
July 5, 2018: Osteoarthritis and Cartilage
Anwar Baban, Marco Castori
Joint hypermobility (JH) is the hallmark of many hereditary soft connective tissue disorders, including Ehlers-Danlos syndromes and related disorders, disorders of the TGFβ-pathway, lateral meningocele syndrome, arterial tortuosity syndrome and cutis laxa syndromes. Contemporary practice separates individuals with isolated, non-syndromic JH, from patients with Mendelian syndromes and those with hypermobility spectrum disorders. The latter is a new nosologic entity grouping together individuals with JH and related musculoskeletal manifestations, but lacking inclusion criteria for well-defined and/or single-gene disorders...
July 6, 2018: Expert Review of Clinical Pharmacology
Diego Costa Astur, Paulo Henrique Schmidt Lara, Marcelo Abdulklech Santos, Gabriel Taniguti DE Oliveira, Gustavo Gonçalves Arliani, Moisés Cohen
Objective: To evaluate the prevalence of joint hypermobility in patients undergoing knee surgery to treat traumatic injury to the meniscus and anterior cruciate ligament, and the influence of this hypermobility on postoperative results. Methods: This prospective study assessed joint hypermobility in patients who underwent surgical reconstruction of the anterior cruciate ligament (ACL), partial meniscectomy, or a procedure combining ACL reconstruction and partial meniscectomy during the period 2011-2015...
January 2018: Acta Ortopedica Brasileira
M Tuijt, A Parsa, M Koutris, W E R Berkhout, J H Koolstra, F Lobbezoo
Patients with hypermobility disorders of the jaw joint experience joint sounds and jerky movements of the jaw. In severe cases, a subluxation or luxation can occur. Clinically, hypermobility disorders should be differentiated from disc displacements. With biomechanical modeling, we previously identified the anterior slope angle of the eminence and the orientation of the jaw closers to potentially contribute to hypermobility disorders. Using cone-beam computed tomography (CBCT), we constructed patient-specific models of the masticatory system to incorporate these aspects...
July 4, 2018: Journal of Oral Rehabilitation
Najla Alsiri, Saud Al-Obaidi, Akram Asbeutah, Mariam Almandeel, Shea Palmer
Hypermobility spectrum disorders (HSDs) are conditions associated with chronic joint pain and laxity. HSD's diagnostic approach is highly subjective, its validity is not well studied, and it does not consider many of the most commonly affected joints. Strain elastography (SEL) reflects musculoskeletal elasticity with sonographic images. The study explored the impact of HSD on musculoskeletal elasticity using SEL. A cross-sectional design compared 21 participants with HSD against 22 controls. SEL was used to assess the elasticity of the deltoid, biceps brachii, brachioradialis, rectus femoris, and gastrocnemius muscles, and the patellar and Achilles tendon...
July 3, 2018: Clinical Rheumatology
Yvonne M Golightly, Marian T Hannan, Amanda E Nelson, Howard J Hillstrom, Rebecca J Cleveland, Virginia B Kraus, Todd A Schwartz, Adam P Goode, Portia Flowers, Jordan B Renner, Joanne M Jordan
OBJECTIVE: To explore associations of joint hypermobility (a condition where range of motion is greater than normal) with ankle and foot radiographic osteoarthritis and symptoms in a large community-based cohort of African American and Caucasian adults 55-94 years old. METHODS: Ankle and foot radiographs and joint hypermobility data (Beighton Criteria) were available for 848 participants (2003-2010) in this cross-sectional study. General joint hypermobility was defined as a Beighton score ≥4 (range 0-9); knee hypermobility was defined as hyperextension of at least one knee...
June 28, 2018: Arthritis Care & Research
Patrizio Antonazzo, Ilenia Di Bartolo, Francesca Parisi, Irene Cetin, Valeria M Savasi
INTRODUCTIONː The role of ultrasound imaging in urogynecology is not defined. Significant developments in visualization techniques and interpretation of images allowed to study structures of the lower genitourinary tract and pelvic floor. EVIDENCE ACQUISITIONː PubMed and Scopus database were searched for publications on the following item: stress urinary incontinence, ultrasound, perineal ultrasound and preoperative and postoperative assessment. EVIDENCE SYNTHESISː The role of ultrasound in urogynecology could be helpful in diagnosing of urinary incontinence and urethral hypermobility, to document pelvic floor anatomy and to assess anatomic and functional changes before and after surgery...
June 27, 2018: Minerva Ginecologica
Adena Zadourian, Taylor A Doherty, Iwona Swiatkiewicz, Pam R Taub
Postural orthostatic tachycardia syndrome (POTS) is a debilitating disease that predominantly affects young women. It is a multifactorial disorder that is characterized by severe tachycardia and orthostatic intolerance. Patients with POTS experience a variety of cardiac, neurological, and immunological symptoms that significantly reduce quality of life. In this review, a comprehensive framework is provided to aid in helping identify and treat patients with POTS. Given its heterogenous nature, it is crucial to understand each component of POTS in relation to one another instead of distinct parts...
July 2018: Drugs
Maurizio S Tonetti, Henry Greenwell, Kenneth S Kornman
BACKGROUND: Authors were assigned the task to develop case definitions for periodontitis in the context of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. The aim of this manuscript is to review evidence and rationale for a revision of the current classification, to provide a framework for case definition that fully implicates state-of-the-art knowledge and can be adapted as new evidence emerges, and to suggest a case definition system that can be implemented in clinical practice, research and epidemiologic surveillance...
June 2018: Journal of Periodontology
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