keyword
https://read.qxmd.com/read/38407357/product-development-within-the-national-institutes-of-health-radiation-and-nuclear-countermeasures-program
#21
JOURNAL ARTICLE
David R Cassatt, Andrea L DiCarlo, Olivia Molinar-Inglis
The Radiation and Nuclear Countermeasures Program (RNCP) at the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) was established to facilitate the development of medical countermeasures (MCMs) and diagnostic approaches for use in a radiation public health emergency. Approvals for MCMs can be very challenging but are made possible under the United States Food and Drug Administration (FDA) Animal Rule, which is designed to enable licensure of drugs or biologics when clinical efficacy studies are unethical or unfeasible...
February 26, 2024: Radiation Research
https://read.qxmd.com/read/38359023/representation-of-the-hierarchical-and-functional-structure-of-an-ambulatory-network-of-medical-consultations-through-social-network-analysis-with-an-emphasis-on-the-role-of-medical-specialties
#22
JOURNAL ARTICLE
Fernando Martín Biscione, Juliano Domingues da Silva
BACKGROUND: Ambulatory Health Care Networks (Amb-HCN) are circuits of patient referral and counter-referral that emerge, explicitly or spontaneously, between doctors who provide care in their offices. Finding a meaningful analytical representation for the organic and hierarchical functioning of an Amb-HCN may have managerial and health policymaking implications. We aimed to characterize the structural and functional topology of an Amb-HCN of a private health insurance provider (PHIP) using objective metrics from graph theory...
2024: PloS One
https://read.qxmd.com/read/38355176/compliance-of-adolescent-friendly-health-clinics-with-national-and-international-standards-quantitative-findings-from-the-i-saathiya-study
#23
JOURNAL ARTICLE
Deepika Bahl, Shalini Bassi, Heeya Maity, Supriya Krishnan, Stefanie Dringus, Amanda Mason-Jones, Anku Malik, Monika Arora
OBJECTIVE: Indian adolescents experience several health challenges requiring acceptable, equitable, appropriate and effective healthcare services. Our objective was to assess the compliance of Adolescent Friendly Health Clinics (AFHCs) in two of India's largest states, using both national benchmarks (under Rashtriya Kishor Swasthya Karyakram-RKSK) and global standards (by WHO). DESIGN: Cross-sectional study comprising structured observations and interactions (November 2021 to June 2022)...
February 13, 2024: BMJ Open
https://read.qxmd.com/read/38318034/a-systematic-review-of-work-related-musculoskeletal-disorders-and-risk-factors-among-computer-users
#24
JOURNAL ARTICLE
Biruk Demissie, Eniyew Tegegne Bayih, Alelign Alemu Demmelash
INTRODUCTION: Rapid technological developments, especially in the use of electronic devices, have affected workers. MSDs are a major burden for both employees and employers, and in contemporary society. Millions of computer workers suffer musculoskeletal diseases and it is the most common cause of occupational illness in the USA and result in medical costs and absenteeism that cost the sector between $45 and $54 billion annually. A single review was done about WMSDs, however it only investigated neck and upper extremities disorders...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38314898/lipiflow-for-the-treatment-of-dry-eye-disease
#25
REVIEW
Andrew D Pucker, Tsz Wing Yim, Erin Rueff, William Ngo, Anna A Tichenor, John E Conto
BACKGROUND: Meibomian gland dysfunction (MGD) is the most common underlying cause of dry eye disease (DED). MGD leads to pathological alteration of the composition or quantity of meibum, or both, which subsequently results in tear evaporation and the typical signs and symptoms associated with DED. The LipiFlow Thermal Pulsation System (LipiFlow) is a medical device used to treat MGD in office; however, it is unclear if LipiFlow can outperform other DED treatments. OBJECTIVES: To evaluate the effectiveness of LipiFlow for treating DED signs and symptoms and the safety of LipiFlow compared with sham or other available treatments for MGD in adults...
February 5, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38293502/prevalence-and-prescribers-knowledge-of-psychotropic-polypharmacy-in-the-bono-bono-east-and-ahafo-regions-ghana
#26
JOURNAL ARTICLE
James Dumba, Antwi Joseph Barimah, Mohammed Mohammed Ibrahim, Solomon Saka Allotey, Semefa Alorvi, William Appertey, Luke Sopaal, Frank Acheampong, Rebecca Dorcas Commey, Yaw Boakye Nketiah, Deborah Ampofo, Bernard Opoku Amoah, Larry Agyemang
The use of psychotropic medications for treating simple and complex psychological and emotional problems is common and relevant among prescribers. This, therefore, come with the tendency to prescribe many medications to a patient on a single visit due to varied reasons. The study, therefore, sought to ascertain the prevalence and prescribers' knowledge of psychotropic polypharmacy. A quantitative, descriptive study was conducted using a simple random approach to select and review the prescription records (both regular and prn basis) of three hundred and nine (309) patients' folders retrospectively within seven (7) mental health units across the study area to ascertain the prevalence of Psychotropic Polypharmacy (PP)...
January 30, 2024: Heliyon
https://read.qxmd.com/read/38285712/coping-health-anxiety-and-stress-among-health-professionals-during-covid-19-cape-coast-ghana
#27
JOURNAL ARTICLE
Anthony K Nkyi, Bridgette Baaba
The aim of this study is to investigate coping strategies, health anxiety and stress among healthcare professionals in selected hospitals in the Cape Coast Metropolis during the Covid 19 pandemic. This study adopted the Descriptive survey design. The Multistage sampling technique was used to select 322 health professionals. The health professionals included Medical Officers, Physician Assistants and Nurses. Data were gathered using the Health Anxiety Inventory (HAI-SF), Perceived Stress Scale (PSS), and the Brief-COPE Inventory...
2024: PloS One
https://read.qxmd.com/read/38281318/radiology-image-interpretation-services-in-a-low-resource-setting-medical-doctors-experiences-and-the-potential-role-of-radiographers
#28
JOURNAL ARTICLE
A Karera, P Engel-Hills, F Davidson
INTRODUCTION: Medical doctors can encounter significant challenges in both the radiology image interpretation service and their ability to interpret images to promote effective patient management. This study aimed to explore the experiences of medical doctors in a low-resource setting regarding the image interpretation service received in state-funded hospitals and the potential role of radiographers. METHODS: A qualitative approach with a descriptive phenomenology design was employed...
January 27, 2024: Radiography
https://read.qxmd.com/read/38271206/rapid-antigen-testing-in-school-health-offices-for-surveillance-of-sars-cov-2-and-influenza-a
#29
JOURNAL ARTICLE
Jonathan Temte, Shari Barlow, Emily Temte, Maureen Goss
Context: Evaluation of acute respiratory infections (ARIs) has been disrupted by the SARS-CoV-2 (SC2) pandemic, limiting comprehensive surveillance for respiratory pathogens in clinical settings. Alternatives to using medically attended ARI for public health surveillance are needed. A potential approach involves assessing children and school personnel in school health offices (SHOs) as pandemic-related responses enhanced innovative approaches for SC2 testing in novel settings. Objective: Evaluate the comparability of SC2 and influenza A (FLuA) detection based on rapid antigen testing in SHOs to traditional surveillance systems...
November 1, 2024: Annals of Family Medicine
https://read.qxmd.com/read/38271105/development-of-a-pharmacy-point-of-dispensing-toolkit-for-anthrax-post-exposure-prophylaxis-for-allegheny-county-postal-workers
#30
JOURNAL ARTICLE
Sarah N Schneider, Thai Q Nguyen, Kelsey L Hake, Barbara S Nightingale, Thomas P Mangan, Amanda N Rice, Joni C Carroll
CONTEXT: The Centers for Disease Control and Prevention (CDC) and the US Postal Service (USPS) consider anthrax to be a potential threat to USPS workers. A county health department-owned pharmacy supports local USPS response in the event of an exposure. The pharmacy team identified the need to review and update the local anthrax response plan. PROGRAM/POLICY: A Pharmacy Point-of-Dispensing Toolkit and response plan for initial 10-day post-exposure antibiotic prophylaxis was developed for use by a local health department in the event of a mass anthrax exposure at a US Post Office sorting facility...
March 2024: Journal of Public Health Management and Practice: JPHMP
https://read.qxmd.com/read/38254201/ala-rdt-in-gbm-protocol-of-the-phase-i-ii-dose-escalation-trial-of-radiodynamic-therapy-with-5-aminolevulinic-acid-in-patients-with-recurrent-glioblastoma
#31
JOURNAL ARTICLE
Niklas Benedikt Pepper, Hans Theodor Eich, Michael Müther, Michael Oertel, Stephan Rehn, Dorothee Cäcilia Spille, Walter Stummer
BACKGROUND: Despite improvements in surgical as well as adjuvant therapies over the last decades, the prognosis for patients with glioblastoma remains poor. Five-Aminolevulinic acid (5-ALA) induced porphyrins are already used for fluorescence-guided resection and as photosensitizer for photodynamic therapy. New findings reveal their potential use as sensitizing agents in combination with ionizing radiation. METHODS: We initiated a phase I/II dose escalation study, treating patients with recurrence of glioblastoma with oral 5-ALA concurrent to radiotherapy (RT)...
January 22, 2024: Radiation Oncology
https://read.qxmd.com/read/38244644/targeted-use-of-postoperative-discharge-phone-calls-to-reduce-early-readmission-rates
#32
JOURNAL ARTICLE
Katherine E Salley, Allison S Crawford, Devon I Robichaud, Gabrielle DeVivo, Robert C Steppacher, Andres Schanzer, Jessica P Simons
OBJECTIVES: Postoperative readmissions are common and costly. Office-initiated phone calls to patients shortly after discharge may identify concerns and allow for early intervention to prevent readmission. We sought to evaluate our 30-day readmission rate after the implementation of a standardized postoperative discharge phone call (PODPC) intervention, compared with a historical aggregated cohort. METHODS: From July 2020 to 21, postoperative patients were prospectively identified at 48 hour after discharge...
January 18, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38236516/rates-of-lower-respiratory-tract-illness-in-us-adults-by-age-and-comorbidity-profile
#33
JOURNAL ARTICLE
Derek Weycker, Ahuva Averin, Linnea Houde, Kevin Ottino, Kimberly Shea, Reiko Sato, Bradford D Gessner, Kari Yacisin, Daniel Curcio, Elizabeth Begier, Mark Rozenbaum
INTRODUCTION: While it is widely recognized that older adults, adults with chronic medical conditions (CMC), and adults with immunocompromising conditions (IC) are at increased risk of lower respiratory tract illness (LRTI), evidence of the magnitude of increased risk is limited. This study was thus undertaken to characterize rates of hospitalized and ambulatory LRTI among United States (US) adults by age and comorbidity profile. METHODS: A retrospective cohort design and US healthcare claims database (2016-2019) were employed...
January 18, 2024: Infectious Diseases and Therapy
https://read.qxmd.com/read/38230851/increasing-injury-intensity-among-6500-violent-deaths-in-the-state-of-maryland
#34
JOURNAL ARTICLE
Joseph V Sakran, Nicole Lunardi, Ambar Mehta, Hiba M Ezzeddine, Majid Chammas, Ryan Fransman, James P Byrne, Kent Stevens, David Efron
BACKGROUND: Anecdotal evidence strongly suggests there has been a rise in violent crimes. This study sought to examine trends in injury characteristics of homicide victims in Maryland. We hypothesized that there would be an increase in the severity of wound characteristics. STUDY DESIGN: The Office of the Chief Medical Examiner is a statewide agency designated by law to investigate all homicides, suicides, or unusual/suspicious circumstances. Using individual autopsy reports, we collected data among all homicides from 2005-2017, categorizing them into three time-periods: 2005-2008 (early), 2009-2013, and 2014-2017 (late)...
January 17, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38225816/the-nurse-police-assistance-crisis-team-n-pact-a-new-role-for-nursing
#35
JOURNAL ARTICLE
Victor G Petreca, Joanne T Barros, Courtney Hoblock, Ann W Burgess
AIM: This study aimed to gain insights into forensic nurses' perspectives and approaches to behavioural crisis situations, comparing them to disciplines traditionally involved in first-line behavioural crisis response. DESIGN: This study used a descriptive, qualitative exploratory design and was informed by Systems Theory. METHODS: The study was carried in the United States, between 2022 and 2023. Data were gathered through four focus groups: police officers (n = 12), co-response (mental health) clinicians (n = 13), sexual assault nurse examiners (n = 6) and correctional nurses (n = 4)...
January 15, 2024: Journal of Advanced Nursing
https://read.qxmd.com/read/38213333/a-knowledge-attitude-and-practice-kap-study-on-phlebotomy-among-nurses-in-a-tertiary-hospital-in-patna-india
#36
JOURNAL ARTICLE
Soma Dey, Neha Rai, Akash Bansal, Bandana Kumari, Bankim Das, Alka Kumari
INTRODUCTION: For most clinicians and nursing officers, laboratory testing is an unfamiliar part of medical caregiving, and ignorance may lead to serious avoidable errors. Phlebotomy, the first basic step towards laboratory testing, is to be taken seriously otherwise unnecessary repeat testing becomes mandatory. We hypothesized that there are some gaps in knowledge, attitude, and practice (KAP) among these nursing officers regarding practices of phlebotomy, which may influence the quality of blood samples...
December 2023: Curēus
https://read.qxmd.com/read/38197151/clinical-trial-design-for-assessing-hypertension-medications-are-critical-circadian-chronopharmacological-principles-being-taking-into-account
#37
JOURNAL ARTICLE
Ramón C Hermida, Michael H Smolensky, Artemio Mojón, José R Fernández
INTRODUCTION: Clinical hypertension trials typically rely on homeostatic principles, including single time-of-day office blood pressure (BP) measurements (OBPM), rather than circadian chronopharmacological principles, including ambulatory monitoring (ABPM) done around-the-clock to derive the asleep systolic BP (SBP) mean and sleep-time relative SBP decline - jointly the strongest prognosticators of cardiovascular disease (CVD) risk and true definition of hypertension - to qualify participants and assess outcomes...
January 10, 2024: Expert Review of Clinical Pharmacology
https://read.qxmd.com/read/38194742/phylogenomic-early-warning-signals-for-sars-cov-2-epidemic-waves
#38
JOURNAL ARTICLE
Kieran O Drake, Olivia Boyd, Vinicius B Franceschi, Rachel M Colquhoun, Nicholas A F Ellaby, Erik M Volz
BACKGROUND: Epidemic waves of coronavirus disease 2019 (COVID-19) infections have often been associated with the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Rapid detection of growing genomic variants can therefore serve as a predictor of future waves, enabling timely implementation of countermeasures such as non-pharmaceutical interventions (social distancing), additional vaccination (booster campaigns), or healthcare capacity adjustments...
January 8, 2024: EBioMedicine
https://read.qxmd.com/read/38190880/two-year-outcomes-after-total-ankle-replacement-with-a-novel-fixed-bearing-implant-by-a-single-surgeon-non-inventor
#39
JOURNAL ARTICLE
Dr James M Cottom, Dr Jay S Badell, Dr Joseph Wolf
Total ankle arthroplasty continues to gain popularity amongst surgeons and patients as an alternative to arthrodesis. Historically the designs of early implants were plagued with complications and frequently abandoned. Since that time the procedure and materials have undergone significant advancements in both surgical approach as well as design and function of the available implants.  In this study, 40 consecutive patients who received a semi-constrained prosthesis with a unique fixed bearing polyethylene insert were identified...
January 6, 2024: Journal of Foot and Ankle Surgery
https://read.qxmd.com/read/38188689/long-term-physical-and-psychological-symptoms-in-syrian-men-subjected-to-detention-conflict-related-sexual-violence-and-torture-cohort-study-of-self-reported-symptom-evolution
#40
JOURNAL ARTICLE
Coleen Kivlahan, Mohammad AlSharif, Ingrid Elliott, Agustin Garcia Pereira, Zina Hallak, Reem Yonso, Ahmad Odaimi, Naser AlHafez, Mahmoud Aswad
BACKGROUND: Since March 2011, more than 1 million people, mostly men, have been arrested, detained, and tortured by the Assad regime. Published literature does not reflect the evolution of symptoms after male sexual and physical violence in detention. This cohort study examines the constellation and evolution of self-reported symptoms after male conflict-related sexual violence (CRSV) in Syrian state detention. METHODS: Sexual, psychological, and physical symptoms and conditions experienced by a cohort of 106 male detainees after CRSV in Syrian regime detention were evaluated over a ten-year period (2012-2022)...
January 2024: EClinicalMedicine
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