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Supannika Kawvised, Jintanaporn Wattanathorn, Wipawee Thukham-Mee
Currently, the neuroprotectant and memory-enhancing agent for menopausal women with metabolic syndrome is required. Based on the advantages of polyphenolics on numerous changes observed in menopause with metabolic syndrome and the encapsulation method, we hypothesized that microencapsulated mulberry fruit extract (MME) could protect brain damage and improve memory impairment in an animal model of menopause with metabolic syndrome. To test this hypothesis, MME at doses of 10, 50, and 250 mg/kg was given to female Wistar rats which were induced experimental menopause with metabolic syndrome by bilateral ovariectomy (OVX) and fed with high-carbohydrate high-fat (HCHF) diet for 8 weeks...
2017: Oxidative Medicine and Cellular Longevity
E Carbó-Laso, P Sanz-Ruiz, J C Del Real-Romero, Y Ballesteros-Iglesias, E Paz-Jiménez, F Arán-Ais, M Sánchez-Navarro, M A Pérez-Limiñana, I López-Torres, J Vaquero-Martín
INTRODUCTION: The increasing antimicrobial resistance is promoting the addition of antibiotics with high antistaphylococcal activity to polymethylmethacrylate (PMMA), for use in cement spacers in periprosthetic joint infection. Linezolid and levofloxacin have already been used in in-vitro studies, however, rifampicin has been shown to have a deleterious effect on the mechanical properties of PMMA, because it inhibits PMMA polymerization. The objective of our study was to isolate the rifampicin during the polymerization process using microencapsulation techniques, in order to obtain a PMMA suitable for manufacturing bone cement spacers...
November 17, 2017: Revista Española de Cirugía Ortopédica y Traumatología
Yuxia Pang, Shengwen Wang, Xueqing Qiu, Yanling Luo, Hongming Lou, Jinhao Huang
Lignin is a vastly underutilized biomass resource. The preparation of water dispersed lignin nanoparticles is an effective way to realize the high-value utilization of lignin. However, the currently reported preparation methods of lignin nanoparticles still have some drawbacks, such as the requirement for toxic organic solvent or chemical modification, complicated operation process and poor dispersibility. Here, lignin/SDS composite nanoparticles (LSNPs) with outstanding water dispersibility and a size range of 70-200 nm were facilely prepared via acidifying the mixed basic solution of alkaline lignin and sodium dodecyl sulfate (SDS)...
November 20, 2017: Journal of Agricultural and Food Chemistry
Maryam Kavosi, Abdorreza Mohammadi, Saeedeh Shojaee-Aliabadi, Ramin Khaksar, Seyede Marzieh Hosseini
BACKGROUND: Purslane seed oil, as a potential nutritious source of omega-3 fatty acid, is susceptible to oxidation. Encapsulation in yeast cells is a possible approach for overcoming this problem. In the present study, purslane seed oil was encapsulated in non-plasmolysed, plasmolysed and plasmolysed carboxy methyl cellulose (CMC)-coated Saccharomyces cerevisiae cells and measurements of oil loading capacity (LC), encapsulation efficiency (EE), oxidative stability and the fatty acid composition of oil-loaded microcapsules were made...
November 14, 2017: Journal of the Science of Food and Agriculture
Hanie Ahmadi, Qi Wang, Loong-Tak Lim, S Balamurugan
Microencapsulation is a versatile method for enhancing the stability of bacteriophages under harsh conditions, such as those which occur during thermal processing. For food applications, encapsulation in food-grade polymer matrices is desirable owing to their nontoxicity and low cost. Here, we describe the encapsulation of Listeria phage A511 using sodium alginate, gum arabic, and gelatin to maximize its viability during thermal processing.
2018: Methods in Molecular Biology
Liu Shi, Sarah K Beamer, Hong Yang, Jacek Jaczynski
This study determined feasibility of krill protein isolated with isoelectric solubilization/precipitation (ISP) as wall material to microencapsulate krill oil by freeze-drying. Effects of krill oil/krill protein ratio on properties of microcapsules were investigated. With increased ratio, crude protein of microcapsules decreased, while total lipid increased. Although microcapsule oil loading capacity increased, loading and encapsulation efficiencies decreased. Thin layer chromatography (TLC) confirmed abundance of phospholipids, which are amphiphilic; and thus, resulted in stable emulsion (emulsion stability index)...
April 1, 2018: Food Chemistry
Yoshinari Taguchi, Takanori Suzuki, Natsukaze Saito, Hiroshi Yokoyama, Masato Tanaka
The soft microcapsules containing Eucalyptus oil, Ubiquinone and the fine water droplets could be prepared with interfacial dehydration reaction between hydroxy methyl cellulose and tannic acid using the (W/O)/W emulsion. The diameters of the microcapsules and the content and the microencapsulation efficiency of the core materials were significantly affected by the revolution velocity (Nr1) to form the (W/O) emulsion and that (Nr2) to form the (W/O)/W emulsion and the lecithin concentration. The mean diameters of the inner water droplets and those of the microcapsules were proportional to Nr1(-1...
November 9, 2017: Journal of Microencapsulation
Huanbin Zhou, Shunyi Li, Yao Chen, Qian Zhang, Xuequn Bai, Chune Zhu, Hu Liu, Lili Wang, Chuanyu Wu, Xin Pan, Chuanbin Wu
Microencapsulation technology has the potential to protect probiotics and to deliver them to the gut, and extrusion is one of the most commonly used methods. However, the rather large diameters of 1~5 mm produced tend to cause oral grittiness and result in low compliance. In this article, Streptococcus thermophilus IFFI 6038 (IFFI 6038) microcapsules were prepared using an ultra-fine particle processing system (UPPS) previously developed by this research group. IFFI 6038 suspension was pumped by a peristaltic pump to the feeding inlet nozzle and then dispersed into micro-droplets by a rotating disk, followed by solidification...
November 6, 2017: AAPS PharmSciTech
Hadi Afrasiabi Garekani, Nasim Sanadgol, Nafiseh Dehghan Nayyeri, Ali Nokhodchi, Fatemeh Sadeghi
Plasticizers play a crucial role in various process of microencapsulation. In this study, the effect of incorporation of plasticizer in process of emulsion solvent evaporation was investigated on properties of ethylcellulose (EC) microcapsules containing propranolol hydrochloride. The effect of plasticizer type and concentration were investigated on characteristics of microcapsules prepared from different viscosity grades of EC. Product yield, encapsulation efficiency, mean particle size, shape, surface characteristics, solid state of drug and drug release profiles were evaluated...
November 3, 2017: Drug Development and Industrial Pharmacy
Claudia M Asensio, Alejandro J Paredes, Maria P Martin, Daniel A Allemandi, Valeria Nepote, Nelson R Grosso
Release kinetics of the volatile compounds of oregano EO microcapsules and the relation with the antioxidant activity were studied. Different wall material (WM) to core (C) ratios (1:1 and 2:1; WM:C), addition of colloidal silicon dioxide (CSD); and different storage conditions: 23 °C (room temperature; R) and 4 °C (fridge temperature; F) were evaluated for 90 d. Volatile compounds, total phenolic content (TPC), free radical scavenging activity (FRSA), and Trolox equivalent antioxidant capacity (TEAC) were measured...
November 2, 2017: Journal of Food Science
Hyunkyu Lee, Heung-Myong Woo, Byung-Jae Kang
The purpose of this study was to identify the effect of collagen-alginate composition on the size and shape of microbeads and the proliferation and osteogenic properties of microencapsulated canine adipose-derived mesenchymal stem cells (ASCs) in vitro. Canine ASCs were microencapsulated in mixtures of various collagen-alginate compositions using a vibrational technologic encapsulator. The size and shape of the resultant microbeads were measured using a light field microscope and the viability of the microencapsulated canine ASCs was evaluated using a live/dead viability/cytotoxicity kit...
October 30, 2017: Journal of Biomaterials Science. Polymer Edition
Ilhwan Park, Carlito Baltazar Tabelin, Kagehiro Magaribuchi, Kensuke Seno, Mayumi Ito, Naoki Hiroyoshi
Arsenopyrite is the most common arsenic-bearing sulfide mineral in nature, and its weathering contributes to acid mine drainage (AMD) formation and the release of toxic arsenic (As). To mitigate this problem, carrier-microencapsulation (CME) using titanium (Ti)-catechol complex (i.e., Ti-based CME) was investigated to passivate arsenopyrite by forming a protective coating. Ti(4+) ion dissolved in sulfuric acid and catechol were used to successfully synthesize Ti(IV) tris-catecholate complex, [Ti(Cat)3](2-), which was stable in the pH range of 5-12...
October 14, 2017: Journal of Hazardous Materials
Lara Zampar Serra Brambilla, Eliana Harue Endo, Diógenes Aparício Garcia Cortez, Marli Miriam de Souza Lima, Benedito Prado Dias Filho
AIMS: This study aims to improve characteristics of Piper regnellii extract to make it applicable in formulations to treat dermatophytosis, also known as ringworm. METHODS AND RESULTS: Microparticles were produced by spray-drying with gelatin, alginate and chitosan as encapsulating agents, characterized by scanning electron microscopy, encapsulation efficiency, thermal analyses, X-ray diffraction, and tested against Trichophyton rubrum by broth microdilution. Produced microparticles had a mean diameter less than 2 μm, an increase in stability and release of the extract and good results for encapsulation efficiency, being 85...
October 26, 2017: Journal of Applied Microbiology
Tae-Wook Lim, Chan Woo Park, Scott R White, Nancy R Sottos
Time release of encapsulated vinylene carbonate (VC) from microcapsules in Li-ion batteries is demonstrated to enhance the rate performance without sacrificing capacity retention. VC-filled microcapsules are successfully prepared by the solvent exchange method that allows VC to diffuse through the microcapsule shell wall at an elevated temperature. The concentration of VC added directly to the electrolyte in a pouch cell (2 wt %) significantly decreases after the first cycle at C/10-rate. In pouch cells that contain 5 wt % VC-filled microcapsules, the concentration of VC increases from 0 to 3 wt % over the first cycle because of the diffusion of microencapsulated VC in the electrolyte...
November 13, 2017: ACS Applied Materials & Interfaces
Laura G Gómez-Mascaraque, Jesús Ambrosio-Martín, Rocío Perez-Masiá, Amparo Lopez-Rubio
In this work, coaxial electrospraying was used for the first time to microencapsulate probiotic bacteria, specifically Lactobacillus plantarum, within edible protein particles with the aim of improving their resistance to in vitro digestion. The developed structures, based on an inner core of whey protein concentrate and an outer layer of gelatin, were obtained in the presence of acetic acid in the outer solution as a requirement for the electrospraying of gelatin. Despite the limited contact of the inner suspension and outer solution during electrospraying, the combination of the high voltage used during electrospraying with the presence of acetic acid was found to have a severe impact on the lactobacilli, not only decreasing initial viability but also negatively affecting the survival of the bacteria during storage and their resistance to different stress conditions, including simulated in vitro digestion...
2017: Journal of Healthcare Engineering
Sara Spinelli, Lucia Lecce, Desislava Likyova, Matteo Alessandro Del Nobile, Amalia Conte
BACKGROUND: The orange industry produces considerable amounts of by-products, traditionally used for animal feed or fuel production. Most of these by-products could be used as functional ingredients. To assess the potential food application of orange epicarp, different percentages of microencapsulated orange extract were added to fresh fish burgers. Then, an in vitro digestion was also carried out, before and after microencapsulation, to measure the bio-accessibility of the active compounds...
October 24, 2017: Journal of the Science of Food and Agriculture
N G Vengerovich, M A Yudin, V N Bykov, A S Nikiforov, O I Aleshina, A A Kuz'min, T M Ustinova, S V Gadzikovskii
We compared samples of microencapsulated naloxone prepared by using spray drying technique. 2-Hydroxypropyl-β-cyclodextrin, sodium alginate, polycaprolactone, and carboxymethyl cellulose were used as the carriers. It was found that the combination of naloxone with sodium alginate was characterized by the highest naloxone content in the matrix and the lowest release rate (100% release time was 60 min). Using the model of respiratory disturbances caused by 10 ED50 fentanyl (anesthetic effect), we studied the effects of naloxone-sodium alginate complex on the dynamics of CO2 concentration in the expired air...
October 2017: Bulletin of Experimental Biology and Medicine
John P McQuilling, Sivanandane Sittadjody, Samuel Pendergraft, Alan C Farney, Emmanuel C Opara
Type-1 Diabetes (T1D) is a devastating autoimmune disorder which results in the destruction of beta cells within the pancreas. A promising treatment strategy for T1D is the replacement of the lost beta cell mass through implantation of immune-isolated microencapsulated islets referred to as the bioartificial pancreas. The goal of this approach is to restore blood glucose regulation and prevent the long-term comorbidities of T1D without the need for immunosuppressants. A major requirement in the quest to achieve this goal is to address the oxygen needs of islet cells...
November 21, 2017: Biomaterials Science
Ana M Kalušević, Steva M Lević, Bojan R Čalija, Jela R Milić, Vladimir B Pavlović, Branko M Bugarski, Viktor A Nedović
The goal of this study was to investigate the characteristics of grape skin extract (GSE) spray dried with different carriers: maltodextrin (MD), gum Arabic (GA) and skim milk powder (SMP). The grape skin extract was obtained from winery by-product of red grape variety Prokupac (Vitis vinifera L.). The morphology of the powders, their thermal, chemical and physical properties (water activity, bulk and tapped densities, solubility), as well as release studies in different pH conditions were analyzed. Total anthocyanin content and total phenolic content were determined by spectrophotometric methods...
October 2017: Journal of Food Science and Technology
Anton Gurkov, Anton Sadovoy, Ekaterina Shchapova, Cathleen Teh, Igor Meglinski, Maxim Timofeyev
In vivo physiological measurement is a major challenge in modern science and technology, as is environment conservation at the global scale. Proper toxicological testing of widely produced mixtures of chemicals is a necessary step in the development of new products, allowing us to minimize the human impact on aquatic ecosystems. However, currently available bioassay-based techniques utilizing small aquatic organisms such as fish embryos for toxicity testing do not allow assessing in time the changes in physiological parameters in the same individual...
2017: PloS One
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