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https://www.readbyqxmd.com/read/28109184/comparative-cardiovascular-risks-of-dipeptidyl-peptidase-4-inhibitors-with-other-2-nd-and-3-rd-line-antidiabetic-drugs-in-patients-with-type-2-diabetes
#1
Huang-Tz Ou, Kai-Cheng Chang, Chung-Yi Li, Jin-Shang Wu
AIMS: Dipeptidyl peptidase-4 inhibitors (DPP4i) are suggested as 2(nd) and 3(rd) add-on antidiabetic treatment for type 2 diabetes. Previous studies only assessed cardiovascular effects of DPP4i as 2(nd) line treatment, included sulfonylurea as only one comparator, and yielded inconclusive results on the risk of heart failure. This study therefore evaluated comparative cardiovascular risks of DPP4i with other 2(nd) and 3(rd) line antidiabetic drugs. METHODS: Based on a large nation-wide diabetic cohort, 113,051 patients with type 2 diabetes newly on metformin-based dual or triple therapy were identified in 2009-2011 and followed until death or 2013...
January 21, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28109006/attitudes-towards-non-invasive-prenatal-diagnosis-among-obstetricians-in-pakistan-a-developing-islamic-country
#2
Shenaz Ahmed, Hussain Jafri, Yasmin Rashid, Gerald Mason, Yasmin Ehsan, Mushtaq Ahmed
OBJECTIVES: Stakeholders' views are essential for informing implementation strategies for non-invasive prenatal testing (NIPT). Little is known about such views in developing countries. We explored attitudes toward NIPT among obstetricians in Pakistan, a developing Islamic country. METHODS: A 35-item questionnaire was distributed and collected at eight events (a national conference and seven workshops in five cities) for obstetric professionals on advances in fetal medicine...
January 20, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28109000/implementation-of-the-7th-edition-ajcc-staging-system-effects-on-staging-and-survival-for-pt1-melanoma-a-dutch-population-based-study
#3
C M C Oude Ophuis, M W J Louwman, D J Grünhagen, C Verhoef, A C J van Akkooi
: In the 7(th) edition of the AJCC staging system the mitotic rate criterion replaced Clark level to increase correct classification of high risk thin melanoma patients (pT1B). Additionally, sentinel node biopsy (SNB) was recommended for nodal staging for pT1B melanomas. AIM: to evaluate the effects on pT1 substaging and clinical implications in the national pT1 melanoma population. All pT1 melanomas diagnosed in the Netherlands between 2003-2014 were selected from the Netherlands Cancer Registry (IKNL)...
January 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28108996/physical-activity-and-risk-of-endometrial-cancer-in-the-norwegian-women-and-cancer-nowac-study
#4
Kristin B Borch, Elisabete Weiderpass, Tonje Braaten, Mie Jareid, Oxana A Gavrilyuk, Idlir Licaj
Few studies have investigated the association between endometrial cancer and physical activity (PA) using repeated measures of PA and different subtypes of endometrial cancer. We aimed to investigate the association between endometrial cancer and PA level at two points in time in women with different body mass index (BMI) profiles, and to calculate the population attributable fraction (PAF) of endometrial cancer for low PA levels. We included 82,759 women with complete information on PA at baseline in the Norwegian Women and Cancer Study; 52,370 had follow-up information on PA...
January 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28108993/experience-from-a-multi-country-initiative-to-improve-the-monitoring-of-selected-reproductive-health-indicators-in-africa
#5
Maria Barreix, Özge Tunçalp, Namuunda Mutombo, Ayotunde A Adegboyega, Lale Say
Universal access to sexual and reproductive health remains part of the unfinished business of global development in the Africa. To achieve it, health interventions should be monitored using programmatic indicators. WHO's Strengthening Measurement of Reproductive Health Indicators in Africa initiative, implemented in Ghana, Nigeria, Kenya, Uganda, and Zimbabwe, aimed to improve national information systems for routine monitoring of reproductive health indicators. Participating countries developed action plans employing a two-pronged strategy: (1) revising, standardizing, and harmonizing existing information-system reproductive health indicators; and (2) building data-collection capacity through training and supervision at select pilot sites...
January 21, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28108941/factors-associated-with-emergency-department-useamong-veteran-psychiatric-patients
#6
Daniel M Blonigen, Kathryn S Macia, Xiaoyu Bi, Paola Suarez, Luisa Manfredi, Todd H Wagner
Frequent utilization of emergency department (ED) services contributes substantially to the cost of healthcare nationally and is often driven by psychiatric factors. Using national-level data from the Veterans Health Administration (VHA), the present study examined patient-level factors associated with ED use among veteran psychiatric patients. Veterans who had at least one ED visit with a psychiatric diagnosis in fiscal years 2011-2012 (n = 226,122) were identified in VHA administrative records. Andersen's behavioral model of healthcare utilization was used to identify need, enabling, and predisposing factors associated with frequency of ED use (primary outcome) in multivariate regression models...
January 21, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28108834/unmet-health-care-needs-among-children-exposed-to-parental-incarceration
#7
Kristin Turney
Objectives The incarceration rate in the United States has increased rapidly since the mid-1970s and, accordingly, a large number of children are exposed to parental incarceration. Research finds that parental incarceration is associated with deleterious physical and mental health outcomes among children, but little is known about these children's health care access. Methods I used data from the 2011-2012 National Survey of Children's Health (N = 95,531), a population-based and nationally representative survey of non-institutionalized children ages 0-17 in the United States, to estimate the association between exposure to parental incarceration and children's unmet health care needs...
January 20, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28108823/which-clinical-and-patient-factors-influence-the-national-economic-burden-of-hospital-readmissions-after-total-joint-arthroplasty
#8
Steven M Kurtz, Edmund C Lau, Kevin L Ong, Edward M Adler, Frank R Kolisek, Michael T Manley
BACKGROUND: The Affordable Care Act of 2010 advanced the economic model of bundled payments for total joint arthroplasty (TJA), in which hospitals will be financially responsible for readmissions, typically at 90 days after surgery. However, little is known about the financial burden of readmissions and what patient, clinical, and hospital factors drive readmission costs. QUESTIONS/PURPOSES: (1) What is the incidence, payer mix, and demographics of THA and TKA readmissions in the United States? (2) What patient, clinical, and hospital factors are associated with the cost of 30- and 90-day readmissions after primary THA and TKA? (3) Are there any differences in the economic burden of THA and TKA readmissions between payers? (4) What types of THA and TKA readmissions are most costly to the US hospital system? METHODS: The recently developed Nationwide Readmissions Database from the Healthcare Cost and Utilization Project (2006 hospitals from 21 states) was used to identify 719,394 primary TJAs and 62,493 90-day readmissions in the first 9 months of 2013 based on International Classification of Diseases, 9th Revision, Clinical Modification codes...
January 20, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28108765/score-study-quality-indicators-for-rheumatology-nursing-clinics
#9
Santiago Muñoz-Fernández, Ma Dolores Aguilar, Raquel Almodóvar, Laura Cano-García, Sandra Fortea, Cristina Patricia Alcañiz-Escandell, José R Rodríguez, Laura Cebrián, Pablo Lázaro
Nursing clinics in rheumatology (NCR) are organizational care models that provide care centred within the scope of nurses abilities. To analyse patients differences in the knowledge of the disease, adherence to the treatment, quality indicators of the Rheumatology Departments included quality perceived by the patients with and without NCR. National multicenter observational prospective cohort study 1 year follow-up, comparing patients attending rheumatology services with and without NCR. NCR was defined by the presence of: (1) office itself; (2) at least one dedicated nurse; (3) its own appointment schedule, and (4) phone...
January 20, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28108747/national-guidelines-for-smoking-cessation-in-primary-care-a-literature-review-and-evidence-analysis
#10
Marjolein Verbiest, Evelyn Brakema, Rianne van der Kleij, Kate Sheals, Georgia Allistone, Siân Williams, Andy McEwen, Niels Chavannes
: National guidelines for smoking cessation in primary care can be effective in improving clinical practice. This study assessed which parties are involved in the development of such guidelines worldwide, which national guidelines address primary care, what recommendations are made for primary care settings, and how these recommendations correlate with each other and with current evidence. We identified national guidelines using an online resource. Only the most recent version of a guideline was included...
December 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28108701/willingness-to-use-and-have-sex-with-men-taking-hiv-pre-exposure-prophylaxis-prep-results-of-online-surveys-of-australian-gay-and-bisexual-men-2011-2015
#11
Martin Holt, Toby Lea, Heather-Marie Schmidt, Johann Kolstee, Jeanne Ellard, Dean Murphy, Hong-Ha Truong, John de Wit
OBJECTIVE: Assess willingness to use HIV pre-exposure prophylaxis (PrEP), support for others using it and willingness to have sex with partners using PrEP among Australian gay and bisexual men (GBM). METHODS: National, online cross-sectional surveys of Australian GBM were conducted in 2011, 2013 and 2015. Scales measuring support for and willingness to have sex with men using PrEP were developed in 2015 using factor analysis. Trends and associations with key measures were analysed using multivariate logistic regression...
January 20, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28108620/adults-miscoded-and-misdiagnosed-as-having-pneumonia-results-from-the-british-thoracic-society-pneumonia-audit
#12
Priya Daniel, Thomas Bewick, Sally Welham, Tricia M Mckeever, Wei Shen Lim
A key objective of the British Thoracic Society national community-acquired pneumonia (CAP) audit was to determine the clinical characteristics and outcomes of hospitalised adults given a primary discharge code of pneumonia but who did not fulfil accepted diagnostic criteria for pneumonia. Adults miscoded as having pneumonia (n=1251) were older compared with adults with CAP (n=6660) (median 80 vs 78 years, p<0.001) and had more comorbid disease, significantly fewer respiratory symptoms (fever, cough, dyspnoea, pleuritic pain), more constitutional symptoms (general deterioration, falls) and significantly lower 30-day inpatient mortality (14...
January 20, 2017: Thorax
https://www.readbyqxmd.com/read/28108593/the-differentiated-effects-of-health-on-political-participation
#13
Jérôme Couture, Sandra Breux
BACKGROUND: Several studies have shown that an individual's state of health can significantly affect their decision to vote, but analysis is often only done on a single level of government; the national level. However, prior research has shown that the determining factors for voting can differ according to the level of government being considered. Our analysis is the first attempt to take a comprehensive look at the magnitude of health and political participation in a same country on different levels...
January 19, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28108592/social-class-variation-the-effect-of-the-economic-recession-and-childhood-obesity-at-3-years-of-age-in-ireland
#14
Samira Barbara Jabakhanji, Milena Pavlova, Wim Groot, Fiona Boland, Regien Biesma
BACKGROUND: Many studies have reported a social class gradient within overweight prevalence (1-4). Additionally, cross-country comparisons report high overweight trends and a change in food consumption patterns in countries affected by an economic crisis (5-11). The aim of this study was to assess the association between social class and recession on obesity levels in 3-year-old Irish children. METHODS: The population-based infant cohort of the national Growing Up in Ireland (GUI) study was used...
January 19, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28108591/quit-attempts-and-smoking-cessation-in-italian-adults-25-64-years-factors-associated-with-attempts-and-successes
#15
Alessandro Coppo, Sandro Baldissera, Alessandro Migliardi, Valentina Minardi, Elisa Quarchioni, Gianluigi Ferrante, Alberto Dal Molin, Fabrizio Faggiano
BACKGROUND: Over the past 50 years there was a substantial decrease in the prevalence of smoking in Italy. The objective of this work is to describe attempts to quit and cessation success in Italian smokers. METHODS: A surveillance on health-related behaviors (PASSI) was conducted in 2007 -: 13 on a sample of 203 610 Italian adults 25 -: 64 years of age. An analysis of smokers' characteristics and behaviors was performed, focusing on attempts to quit and quit success...
January 19, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28108530/use-of-performance-metrics-for-the-measurement-of-universal-coverage-for-maternal-care-in-mexico
#16
Edson Serván-Mori, David Contreras-Loya, Octavio Gomez-Dantés, Gustavo Nigenda, Sandra G Sosa-Rubí, Rafael Lozano
This study provides evidence for those working in the maternal health metrics and health system performance fields, as well as those interested in achieving universal and effective health care coverage. Based on the perspective of continuity of health care and applying quasi-experimental methods to analyse the cross-sectional 2009 National Demographic Dynamics Survey (n = 14 414 women), we estimated the middle-term effects of Mexico's new public health insurance scheme, Seguro Popular de Salud (SPS) (vs women without health insurance) on seven indicators related to maternal health care (according to official guidelines): (a) access to skilled antenatal care (ANC); (b) timely ANC; (c) frequent ANC; (d) adequate content of ANC; (e) institutional delivery; (f) postnatal consultation and (g) access to standardized comprehensive antenatal and postnatal care (or the intersection of the seven process indicators)...
January 20, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28108499/relay-balloon-technique-for-recanalization-of-acute-symptomatic-proximal-internal-carotid-artery-occlusion-with-short-balloon-tipped-guiding-catheter-landing-zone
#17
Sang Hun Lee, Dong Geun Lee, Sun U Kwon, Deok Hee Lee
BACKGROUND: Endovascular recanalization of a completely occluded proximal internal carotid artery (ICA) with underlying stenosis may be challenging owing to a possible thrombotic component. This is especially true when the landing zone for a balloon-tipped guiding catheter (BGC) at the bulb portion is insufficient. Sequential application of the balloons of a BGC and an angioplasty catheter may prevent thromboembolism during revascularization. This study analyzed the safety and effectiveness of this relay-balloon technique...
January 20, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28108367/a-propensity-score-matched-analysis-of-the-impact-of-minimum-inhibitory-concentration-on-mortality-in-patients-with-pseudomonas-aeruginosa-bacteraemia-treated-with-piperacillin-tazobactam
#18
Chris A Gentry, Riley J Williams
The Clinical and Laboratory Standards Institute (CLSI) recently re-examined Pseudomonas aeruginosa minimum inhibitory concentration (MIC) susceptibility breakpoints for piperacillin/tazobactam (TZP). The objectives of this study were to analyse the impact of elevated TZP MICs (32-64 mg/L) versus lower respective MICs on P. aeruginosa bacteraemia patient outcomes. Data were gathered from a Veterans Health Administration national clinical database on P. aeruginosa bacteraemia episodes from 2007 to 2013. Patients treated with TZP were identified, comprising 53 elevated MIC episodes and 301 low MIC episodes...
January 17, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28108269/are-hemoglobin-levels-really-lower-in-faecal-immunochemical-test-positive-patients-with-colorectal-cancer
#19
Jing Yu Ng, Ian Jse-Wei Tan, Ker-Kan Tan
INTRODUCTION: Faecal immunochemical test (FIT) is advocated in many colorectal cancer-screening programs. A positive FIT translates to the need for a colonoscopy. However, waiting times for diagnostic colonoscopy is long. The aim of our study is to determine the correlation of hemoglobin levels in patients with a positive FIT who were subsequently diagnosed with colorectal cancer, and to compare them with patients with only colonic adenomas and those with normal colonoscopy with the intention of determining if hemoglobin levels could be used to stratify the urgency of colonoscopy...
January 17, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28108238/effect-of-an-evidence-based-guideline-on-the-treatment-of-maxillofacial-cancer-a-prospective-analysis
#20
Klaus-Dietrich Wolff, Andrea Rau, Julia Ferencz, Thomas Langer, Marco Kesting, Markus Nieberler, Simone Wesselmann
BACKGROUND: In 2012, a guideline for the diagnosis and treatment of oral cavity cancer based on the best available evidence was implemented at certified German cancer centres for head and neck carcinomas. The present analysis was performed to determine whether the implementation of the guideline via certification improved the level of care, leading to a benefit for the patients. METHODS: A prospective observational study was performed based on the annual operating figures at 31 certified head and neck cancer centres...
December 20, 2016: Journal of Cranio-maxillo-facial Surgery
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