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Christine courtois

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https://www.readbyqxmd.com/read/27045564/the-burden-of-venipuncture-pain-in-neonatal-intensive-care-units-epippain-2-a-prospective-observational-study
#1
Emilie Courtois, Patricia Cimerman, Valérie Dubuche, Marie-France Goiset, Claire Orfèvre, Audrey Lagarde, Betty Sgaggero, Céline Guiot, Mélanie Goussot, Etienne Huraux, Marie-Christine Nanquette, Céline Butel, Anne-Marie Ferreira, Sylvie Lacoste, Sandrine Séjourné, Valérie Jolly, Gladys Lajoie, Valérie Maillard, Romain Guedj, Hélène Chappuy, Ricardo Carbajal
BACKGROUND: Newborns in intensive care units (ICUs) undergo numerous painful procedures including venipunctures. Skin-breaking procedures have been associated with adverse neurodevelopment long-term effects in very preterm neonates. The venipuncture frequency and its real bedside pain management treatment are not well known in this setting. OBJECTIVES: To describe venipuncture frequency, its pain intensity, and the analgesic approach in ICU newborns; to determine the factors associated with the lack of preprocedural analgesia and with a high pain score during venipuncture...
May 2016: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/26454080/targeting-iron-mediated-retinal-degeneration-by-local-delivery-of-transferrin
#2
Emilie Picard, Quentin Le Rouzic, Antonin Oudar, Marianne Berdugo, Mohamed El Sanharawi, Charlotte Andrieu-Soler, Marie-Christine Naud, Laurent Jonet, Chloé Latour, Christophe Klein, Stéphane Galiacy, François Malecaze, Hélène Coppin, Marie-Paule Roth, Jean-Claude Jeanny, Yves Courtois, Francine Behar-Cohen
Iron is essential for retinal function but contributes to oxidative stress-mediated degeneration. Iron retinal homeostasis is highly regulated and transferrin (Tf), a potent iron chelator, is endogenously secreted by retinal cells. In this study, therapeutic potential of a local Tf delivery was evaluated in animal models of retinal degeneration. After intravitreal injection, Tf spread rapidly within the retina and accumulated in photoreceptors and retinal pigment epithelium, before reaching the blood circulation...
December 2015: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/26388117/delayed-onset-friedreich-s-ataxia-revisited
#3
MULTICENTER STUDY
Claire Lecocq, Perrine Charles, Jean-Philippe Azulay, Wassilios Meissner, Myriam Rai, Karine N'Guyen, Yann Péréon, Nelly Fabre, Elsa Robin, Sylvie Courtois, Lucie Guyant-Maréchal, Fabien Zagnoli, Gabrielle Rudolf, Mathilde Renaud, Mathieu Sévin-Allouet, Fabien Lesne, Nick Alaerts, Cyril Goizet, Patrick Calvas, Alexandre Eusebio, Claire Guissart, Pascal Derkinderen, Francois Tison, Alexis Brice, Michel Koenig, Massimo Pandolfo, Christine Tranchant, Alexandra Dürr, Mathieu Anheim
BACKGROUND: Friedreich's ataxia usually occurs before the age of 25. Rare variants have been described, such as late-onset Friedreich's ataxia and very-late-onset Friedreich's ataxia, occurring after 25 and 40 years, respectively. We describe the clinical, functional, and molecular findings from a large series of late-onset Friedreich's ataxia and very-late-onset Friedreich's ataxia and compare them with typical-onset Friedreich's ataxia. METHODS: Phenotypic and genotypic comparison of 44 late-onset Friedreich's ataxia, 30 very late-onset Friedreich's ataxia, and 180 typical Friedreich's ataxia was undertaken...
January 2016: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/26339487/susceptibility-to-cognitive-distortions-the-role-of-eating-pathology
#4
Jennifer S Coelho, Catherine Ouellet-Courtois, Christine Purdon, Howard Steiger
BACKGROUND: Thought-Shape Fusion (TSF) and Thought-Action Fusion (TAF) are cognitive distortions that are associated with eating and obsessional pathology respectively. Both involve the underlying belief that mere thoughts and mental images can lead to negative outcomes. TSF involves the belief that food-related thoughts lead to weight gain, body dissatisfaction, and perceptions of moral wrong-doing. TAF is more general, and involves the belief that merely thinking about a negative event (e...
2015: Journal of Eating Disorders
https://www.readbyqxmd.com/read/25778986/identification-of-early-nuclear-target-genes-of-plastidial-redox-signals-that-trigger-the-long-term-response-of-arabidopsis-to-light-quality-shifts
#5
Lars Dietzel, Christine Gläßer, Monique Liebers, Stefan Hiekel, Florence Courtois, Olaf Czarnecki, Hagen Schlicke, Yan Zubo, Thomas Börner, Klaus Mayer, Bernhard Grimm, Thomas Pfannschmidt
Natural illumination conditions are highly variable and because of their sessile life style, plants are forced to acclimate to them at the cellular and molecular level. Changes in light intensity or quality induce changes in the reduction/oxidation (redox) state of the photosynthetic electron chain that acts as a trigger for compensatory acclimation responses comprising functional and structural adjustments of photosynthesis and metabolism. Such responses include redox-controlled changes in plant gene expression in the nucleus and organelles...
August 2015: Molecular Plant
https://www.readbyqxmd.com/read/25398856/highly-dynamic-genomic-loci-drive-the-synthesis-of-two-types-of-capsular-or-secreted-polysaccharides-within-the-mycoplasma-mycoides-cluster
#6
Clothilde Bertin, Corinne Pau-Roblot, Josiane Courtois, Lucía Manso-Silván, Florence Tardy, François Poumarat, Christine Citti, Pascal Sirand-Pugnet, Patrice Gaurivaud, François Thiaucourt
Mycoplasmas of the Mycoplasma mycoides cluster are all ruminant pathogens. Mycoplasma mycoides subsp. mycoides is responsible for contagious bovine pleuropneumonia and is known to produce capsular polysaccharide (CPS) and exopolysaccharide (EPS). Previous studies have strongly suggested a role for Mycoplasma mycoides subsp. mycoides polysaccharides in pathogenicity. Mycoplasma mycoides subsp. mycoides-secreted EPS was recently characterized as a β(1→6)-galactofuranose homopolymer (galactan) identical to the capsular product...
January 2015: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/24566807/switching-from-natalizumab-to-fingolimod-in-multiple-sclerosis-a-french-prospective-study
#7
MULTICENTER STUDY
Mikael Cohen, Elisabeth Maillart, Ayman Tourbah, Jérôme De Sèze, Sandra Vukusic, David Brassat, Olivier Anne, Sandrine Wiertlewski, William Camu, Sylvie Courtois, Aurélie Ruet, Marc Debouverie, Emmanuelle Le Page, Olivier Casez, Olivier Heinzlef, Bruno Stankoff, Bertrand Bourre, Giovanni Castelnovo, Audrey Rico, Eric Berger, Jean-Philippe Camdessanche, Gilles Defer, Pierre Clavelou, Abdullatif Al Khedr, Hélène Zephir, Agnès Fromont, Caroline Papeix, Bruno Brochet, Jean Pelletier, Christine Lebrun
IMPORTANCE: The safety and efficacy of switching from natalizumab to fingolimod have not yet been evaluated in a large cohort of patients with multiple sclerosis (MS) to our knowledge. OBJECTIVE: To collect data from patients with MS switching from natalizumab to fingolimod. DESIGN, SETTING, AND PARTICIPANTS: The Enquête Nationale sur l'Introduction du Fingolimod en Relais au Natalizumab (ENIGM) study, a survey-based, observational multicenter cohort study among MS tertiary referral centers...
April 2014: JAMA Neurology
https://www.readbyqxmd.com/read/23741532/responses-of-a-sample-of-practicing-psychologists-to-questions-about-clinical-work-with-trauma-and-interest-in-specialized-training
#8
Joan M Cook, Omar Rehman, Lynn Bufka, Stephanie Dinnen, Christine Courtois
This study reports on selected findings from a survey conducted by the American Psychological Association Practice Organization, which assessed the number of hours per month that practicing psychologists estimated they spent treating trauma survivors and their interest in additional clinical training on trauma-related issues and topics. Respondents reported 14.3 mean number of hours spent working with trauma survivors over the past month. Of the 76% of the sample who treated any trauma patients, the mean was 16...
September 1, 2011: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/23261128/development-of-superhydrophilic-and-superhydrophobic-polyester-fabric-by-growing-zinc-oxide-nanorods
#9
Munir Ashraf, Christine Campagne, Anne Perwuelz, Philippe Champagne, Anne Leriche, Christian Courtois
ZnO nanorods were grown on microfibers of Polyethylene terephthalate (PET) fabric by seeding method to develop hierarchical roughness structure. XRD and XPS analysis show the presence of crystalline ZnO and chemical Zn species at the fiber surface at each stage of the process. Five series of samples with different seed concentrations have been realized, and their surface morphology and topography were characterized by AFM and SEM. Increasing seed concentrations lead to samples with superhydrophilic properties...
March 15, 2013: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/23190530/eklf-driven-pit1-expression-is-critical-for-mouse-erythroid-maturation-in-vivo-and-in-vitro
#10
Anne Forand, Laurent Beck, Christine Leroy, Alice Rousseau, Valérie Boitez, Isabelle Cohen, Geneviève Courtois, Olivier Hermine, Gérard Friedlander
The PIT1/SLC20A1 protein, a well-described sodium/phosphate cotransporter and retrovirus receptor, has been identified recently as a modular of proliferation and apoptosis in vitro. The targeted deletion of the PIT1 gene in mice revealed a lethal phenotype due to severe anemia attributed to defects in liver development. However, the presence of immature erythroid cells associated with impaired maturation of the globin switch led us to investigate the role of PIT1 in hematopoietic development. In the present study, specific deletion of PIT1 in the hematopoietic system and fetal liver transplantation experiments demonstrated that anemia was associated with an erythroid cell- autonomous defect...
January 24, 2013: Blood
https://www.readbyqxmd.com/read/22998014/plasma-transfusion-in-liver-transplantation-a-randomized-double-blind-multicenter-clinical-comparison-of-three-virally-secured-plasmas
#11
RANDOMIZED CONTROLLED TRIAL
Tonine Bartelmaos, Anne Chabanel, Julie Léger, Loïc Villalon, Marie Christine Gillon, Claude Rouget, Alexandra Gomola, Marie Hélène Denninger, René Tardivel, Christian Naegelen, Françoise Courtois, Laurent Bardiaux, Bruno Giraudeau, Yves Ozier
BACKGROUND: The clinical equivalence of plasma treated to reduce pathogen transmission and untreated plasma has not been extensively studied. A clinical trial was conducted in liver transplant recipients to compare the efficacy of three plasmas. STUDY DESIGN AND METHODS: A randomized, equivalence, blinded trial was performed in four French liver transplantation centers. The three studied (fresh-frozen) plasmas were quarantine (Q-FFP), methylene blue (MB-FFP), and solvent/detergent (S/D-FFP) plasmas...
June 2013: Transfusion
https://www.readbyqxmd.com/read/22147449/treatment-of-complex-ptsd-results-of-the-istss-expert-clinician-survey-on-best-practices
#12
Marylene Cloitre, Christine A Courtois, Anthony Charuvastra, Richard Carapezza, Bradley C Stolbach, Bonnie L Green
This study provides a summary of the results of an expert opinion survey initiated by the International Society for Traumatic Stress Studies Complex Trauma Task Force regarding best practices for the treatment of complex posttraumatic stress disorder (PTSD). Ratings from a mail-in survey from 25 complex PTSD experts and 25 classic PTSD experts regarding the most appropriate treatment approaches and interventions for complex PTSD were examined for areas of consensus and disagreement. Experts agreed on several aspects of treatment, with 84% endorsing a phase-based or sequenced therapy as the most appropriate treatment approach with interventions tailored to specific symptom sets...
December 2011: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/20454772/structure-allelic-diversity-and-selection-of-asr-genes-candidate-for-drought-tolerance-in-oryza-sativa-l-and-wild-relatives
#13
Romain Philippe, Brigitte Courtois, Kenneth L McNally, Pierre Mournet, Redouane El-Malki, Marie Christine Le Paslier, Denis Fabre, Claire Billot, Dominique Brunel, Jean-Christophe Glaszmann, Dominique This
Asr (ABA, stress, ripening) genes represent a small gene family potentially involved in drought tolerance in several plant species. To analyze their interest for rice breeding for water-limited environments, this gene family was characterized further. Genomic organization of the gene family reveals six members located on four different chromosomes and with the same exon-intron structure. The maintenance of six members of the Asr gene family, which are the result of combination between tandem duplication and whole genome duplication, and their differential regulation under water stress, involves probably some sub-functionalization...
August 2010: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/18466272/perceived-physiological-and-orgasmic-sensations-at-ejaculation-in-spinal-cord-injured-men
#14
Frédérique Courtois, Kathleen Charvier, Albert Leriche, Jean-Guy Vézina, Isabelle Côté, Denis Raymond, Géraldine Jacquemin, Christine Fournier, Marc Bélanger
INTRODUCTION: With the advances in penile vibrator stimulation (PVS), most spinal cord injured (SCI) men can self-ejaculate. Oral midodrine may further increase ejaculation success, while maintaining autonomy. Since most SCI men attempt ejaculation for sexual rather than reproductive purposes, self-ejaculation should be emphasized and sensations explored. AIMS: Explore (i) self-ejaculation success rate in SCI men; (ii) vascular parameters indicative of autonomic dysreflexia (AD) during sexual stimulation and ejaculation; and (iii) sensations associated with ejaculation...
October 2008: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/16913604/-a-flying-library-in-long-term-care
#15
Christine Courtois
No abstract text is available yet for this article.
July 2006: Soins. Gérontologie
https://www.readbyqxmd.com/read/16281242/clinical-applications-of-the-attachment-framework-relational-treatment-of-complex-trauma
#16
REVIEW
Laurie Anne Pearlman, Christine A Courtois
The self and attachment difficulties associated with chronic childhood abuse and other forms of pervasive trauma must be understood and addressed in the context of the therapeutic relationship for healing to extend beyond resolution of traditional psychiatric symptoms and skill deficits. The authors integrate contemporary research and theory about attachment and complex developmental trauma, including dissociation, and apply it to psychotherapy of complex trauma, especially as this research and theory inform the therapeutic relationship...
October 2005: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/16281241/treatment-of-complex-posttraumatic-self-dysregulation
#17
REVIEW
Julian D Ford, Christine A Courtois, Kathy Steele, Onno van der Hart, Ellert R S Nijenhuis
The authors describe a three-phase sequential integrative model for the psychotherapy of complex posttraumatic self-dysregulation: Phase 1 (alliance formation and stabilization), Phase 2 (trauma processing), and Phase 3 (functional reintegration). The technical precautions designed to maximize safety, trauma processing, and reintegration regardless of the specific treatment approach are discussed. Existing and emerging treatment models that address posttraumatic dysregulation of consciousness, bodily functioning, emotion, and interpersonal attachments are also described...
October 2005: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/16281236/editorial-comments-complex-developmental-trauma
#18
EDITORIAL
Bessel A van der Kolk, Christine A Courtois
No abstract text is available yet for this article.
October 2005: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/15606764/escherichia-coli-cyclopropane-fatty-acid-synthase
#19
Fabienne Courtois, Christine Guérard, Xavier Thomas, Olivier Ploux
Escherichia coli fatty acid cyclopropane synthase (CFAS) was overproduced and purified as a His6-tagged protein. This recombinant enzyme is as active as the native enzyme with a Km of 90 microm for S-AdoMet and a specific activity of 5 x 10(-2) micromol.min(-1).mg(-1). The enzyme is devoid of organic or metal cofactors and is unable to catalyze the wash-out of the methyl protons of S-AdoMet to the solvent, data that do not support the ylide mechanism. Inactivation of the enzyme by 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB), a pseudo first-order process with a rate constant of 1...
December 2004: European Journal of Biochemistry
https://www.readbyqxmd.com/read/15170389/interaction-of-the-tyrosine-phosphatase-shp-2-with-gab2-regulates-rho-dependent-activation-of-the-c-fos-serum-response-element-by-interleukin-2
#20
Mary Arnaud, Rym Mzali, Franck Gesbert, Catherine Crouin, Christine Guenzi, Claudine Vermot-Desroches, John Wijdenes, Geneviève Courtois, Olivier Bernard, Jacques Bertoglio
Gab2 (Grb2-associated binder-2), a member of the IRS (insulin receptor substrate)/Gab family of adapter proteins, undergoes tyrosine phosphorylation in response to cytokine or growth factor stimulation and serves as a docking platform for many signal transduction effectors, including the tyrosine phosphatase SHP-2 [SH2 (Src homology 2)-domain-containing tyrosine phosphatase]. Here, we report that, following IL-2 (interleukin-2) stimulation of human T lymphocytes, SHP-2 binds tyrosine residues 614 and 643 of human Gab2 through its N- and C-terminal SH2 domains respectively...
September 1, 2004: Biochemical Journal
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