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https://www.readbyqxmd.com/read/29226832/the-current-treatment-landscape-of-irritable-bowel-syndrome-in-adults-in-hong-kong-consensus-statements
#1
J Cy Wu, A Oo Chan, Y W Chan, G Cl Cheung, T K Cheung, A Cp Kwan, V Ks Leung, A Dp Mak, W C Sze, R Wong
OBJECTIVE: The estimated prevalence of irritable bowel syndrome in Hong Kong is 6.6%. With the increasing availability of pharmacological and non-pharmacological treatments, the Hong Kong Advisory Council on Irritable Bowel Syndrome has developed a set of consensus statements intended to serve as local recommendations for clinicians about diagnosis and management of irritable bowel syndrome. PARTICIPANTS: A multidisciplinary group of clinicians constituting the Hong Kong Advisory Council on Irritable Bowel Syndrome-seven gastroenterologists, one clinical psychologist, one psychiatrist, and one nutritionist-convened on 20 April 2017 in Hong Kong...
December 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29225668/advanced-image-enhancement-method-for-distant-vessels-and-structures-in-capsule-endoscopy
#2
Olivier Rukundo, Marius Pedersen, Øistein Hovde
This paper proposes an advanced method for contrast enhancement of capsule endoscopic images, with the main objective to obtain sufficient information about the vessels and structures in more distant (or darker) parts of capsule endoscopic images. The proposed method (PM) combines two algorithms for the enhancement of darker and brighter areas of capsule endoscopic images, respectively. The half-unit weighted-bilinear algorithm (HWB) proposed in our previous work is used to enhance darker areas according to the darker map content of its HSV's component V...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29225082/comparison-of-eus-with-magnetic-resonance-cholangiopancreatography-in-idiopathic-acute-pancreatitis-a-systematic-review-and-meta-analysis
#3
REVIEW
Jianhua Wan, Yaobin Ouyang, Chen Yu, Xiaoyu Yang, Liang Xia, Nonghua Lu
BACKGROUND: /Aims: Idiopathic acute pancreatitis (IAP) poses a diagnostic challenge for gastroenterologists, as confirmation of the disease etiology has important implications for the selection of the best possible treatment and the prevention of possible recurrence or the development of chronic pancreatitis. ERCP, EUS, and magnetic resonance cholangiopancreatography (MRCP) are typically used to diagnose IAP when conventional radiological methods fail. However, their exact role in the diagnosis of IAP has not yet been determined...
December 7, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29218318/patient-comfort-scores-do-not-affect-endoscopist-behavior-during-colonoscopy-while-trainee-involvement-has-negative-effects-on-patient-comfort
#4
Brian P H Chan, Amanda Hussey, Natalie Rubinger, Lawrence C Hookey
Introduction : Patient comfort is an important part of endoscopy and reflects procedure quality and endoscopist technique. Using the validated, Nurse Assisted Patient Comfort Score (NAPCOMS), this study aimed to determine whether the introduction of NAPCOMS would affect sedation use by endoscopists. Patients and methods : The study was conducted over 3 phases. Phase One and Two consisted of 8 weeks of endoscopist blinded and aware data collection, respectively...
December 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29218313/factors-associated-with-number-of-duodenal-samples-obtained-in-suspected-celiac-disease
#5
Leonid Shamban, Serge Sorser, Stan Naydin, Benjamin Lebwohl, Mousa Shukr, Charlotte Wiemann, Daniel Yevsyukov, Michael H Piper, Bradley Warren, Peter H R Green
Background and study aims:  Many people with celiac disease are undiagnosed and there is evidence that insufficient duodenal samples may contribute to underdiagnosis. The aims of this study were to investigate whether more samples leads to a greater likelihood of a diagnosis of celiac disease and to elucidate factors that influence the number of samples collected. Patients and methods:  We identified patients from two community hospitals who were undergoing duodenal biopsy for indications (as identified by International Classification of Diseases code) compatible with possible celiac disease...
December 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29216349/developing-a-standard-set-of-patient-centred-outcomes-for-inflammatory-bowel-disease-an-international-cross-disciplinary-consensus
#6
Andrew H Kim, Charlotte Roberts, Brian G Feagan, Rupa Banerjee, Willem Bemelman, Keith Bodger, Marc Derieppe, Axel Dignass, Richard Driscoll, Ray Fitzpatrick, Janette Gaarentstroom-Lunt, Peter D Higgins, Paulo Gustavo Kotze, Jillian Meissner, Marian O'Connor, Zhi-Hua Ran, Corey A Siegel, Helen Terry, Welmoed K van Deen, C Janneke van der Woude, Alandra Weaver, Suk-Kyun Yang, Bruce E Sands, Séverine Vermeire, Simon Pl Travis
Background and Aims: Success in delivering value-based healthcare involves measuring outcomes that matter most to patients. Our aim was to develop a minimum Standard Set of patient-centred outcome measures for inflammatory bowel disease (IBD), for use in different healthcare settings. Methods: An international working group (n=25) representing patients, patient associations, gastroenterologists, surgeons, specialist nurses, IBD registries and patient-reported outcome measure (PROM) methodologists participated in a series of teleconferences incorporating a modified Delphi process...
December 5, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29212101/invitation-letters-increase-participation-in-colorectal-cancer-screening-results-from-an-observational-study
#7
Tianzuo Zhan, Thomas Hielscher, Asmé Bilge, Thomas Giese, Christoph Schäfer, Jürgen F Riemann, Matthias P Ebert, Sebastian Belle
Background and Aim Participation rates in the German colorectal cancer screening program are low. Starting in 2013, a large health insurance plan in Bavaria, Germany, is sending an additional invitation letter to insured individuals when they turn 50 or 55 years and become eligible for participation in the program. The letter provides detailed information on colorectal cancer screening. We assessed the impact of the invitation letter on utilization rates. Methods Insurance claims data of a total of 48 343 individuals who had turned 50 or 55 years between 2012 to 2014 were reviewed for utilization rates of screening colonoscopy and fecal blood tests...
December 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29207229/-bilirubin-removal-with-coupled-plasma-filtration-and-adsorption-in-patients-affected-by-hilar-cholangiocarcinoma
#8
Walter De Simone, Francesco Crafa, Adele Noviello, Francesco Esposito, Bruno Zito, Rocco Manganelli, Antonella De Simone, Luigi Covotta, Giuseppe Palladino, Emanuele De Simone
Background: Patients affected by hilar cholangiocarcinoma are eligible for surgery only in the 20-30% of the cases and postoperative mortality is 40-50%. Many specialists are involved in the treatment of this disease, like surgeons, gastroenterologists, oncologists and radiotherapists. Recent studies have shown that preoperative bilirubinaemia is a predictor of morbidity and mortality after surgery. Coupled Plasma Filtration and Adsorption (CPFA) is a blood purification extracorporeal therapy recommended for sepsis and able to reduce bilirubinaemia...
December 5, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/29203343/wide-variation-in-organisation-and-clinical-practice-of-paediatric-intestinal-failure-teams-an-international-survey
#9
Esther Neelis, Barbara de Koning, Myriam van Winckel, Merit Tabbers, Susan Hill, Jessie Hulst
BACKGROUND & AIMS: We aimed to assess the current organisation and clinical practice of teams treating children with intestinal failure (IF) across Europe and compare the results with the current guideline. METHODS: A two-part online survey was sent to all the major European specialist IF services. The first part concerned general information about the team and patients monitored. The second part concerned important care topics such as vascular access and monitoring of complications...
November 22, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29199159/how-is-gastroesophageal-reflux-disease-classified
#10
Filiz Akyüz, Özlem Mutluay Soyer
Gastroesophageal reflux disease (GERD) is one of the most commonly diagnosed conditions in the daily practice of gastroenterologists. Due to variations in symptoms and clinical findings, differences in the severity of the disease in each patient and the fact that diverse methods are used for making a diagnosis makes a single and standard classification of this disease impossible. Here a step-approach suitable for GERD classification is summarized.
December 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/29192650/intramucosal-lipomas-of-the-colon-implicate-cowden-syndrome
#11
Aybuke Caliskan, Wendy K Kohlmann, Kajsa E Affolter, Erinn Downs-Kelly, Priyanka Kanth, Mary P Bronner
Intramucosal lipomas are rare and easily overlooked by pathologists, despite their diagnostic significance for Cowden syndrome (PTEN hamartoma tumor syndrome), an inherited multiorgan cancer syndrome. Only 25-35% of patients harbor identifiable PTEN mutations, thus clinical features, like intramucosal lipomas, remain the mainstay of diagnosis. The significance and diagnostic approach to intramucosal lipomas have not been thoroughly addressed in the literature. Intramucosal lipomas are mimicked by pseudolipomatosis coli, an artifactual mucosal gas infiltration from endoscopic insufflation...
December 1, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29189514/somatic-ptpn11-mutation-in-a-child-with-neuroblastoma-and-protein-losing-enteropathy
#12
Patience Obasaju, Jennifer Brondon, Sabina Mir, Lynn A Fordham, Sang Lee, Julie Blatt
Neuroblastoma and protein losing enteropathy (PLE) are diagnoses commonly seen by oncologists and gastroenterologists, respectively. The concurrence of these 2 entities is rare, and not well explained. We describe the sixth case of PLE in a child with neuroblastoma, and the first for which genetic information is available. Tumor DNA had a mutation in the PTPN11 gene, which has been described in neuroblastoma, and in Noonan syndrome-a diagnosis in which neuroblastoma and PLE independently have been reported...
November 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29184610/colonoscopy-procedural-volume-increases-adenoma-and-polyp-detection-rates-in-gastroenterologytrainees
#13
Emad Qayed, Ravi Vora, Sara Levy, Roberd M Bostick
AIM: To investigate changes in polyp detection throughout fellowship training, and estimate colonoscopy volume required to achieve the adenoma detection rate (ADRs) and polyp detection rate (PDRs) of attending gastroenterologists. METHODS: We reviewed colonoscopies from July 1, 2009 to June 30, 2014. Fellows' procedural logs were used to retrieve colonoscopy procedural volumes, and these were treated as the time variable. Findings from screening colonoscopies were used to calculate colonoscopy outcomes for each fellow for the prior 50 colonoscopies at each time point...
November 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29184185/cellular-senescence-in-gastrointestinal-diseases-from-pathogenesis-to-therapeutics
#14
REVIEW
Nina Frey, Sascha Venturelli, Lars Zender, Michael Bitzer
Senescence is a durable cell cycle arrest that can be induced in response to various stress factors, such as telomere erosion, DNA damage or the aberrant activation of oncogenes. In addition to its well-established role as a stress response programme, research has revealed important physiological roles of senescence in nondisease settings, such as embryonic development, wound healing, tissue repair and ageing. Senescent cells secrete various cytokines, chemokines, matrix remodelling proteases and growth factors, a phenotype collectively referred to as the senescence-associated secretory phenotype...
November 29, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29181702/geoepidemiology-of-primary-biliary-cholangitis-lessons-from-switzerland
#15
Benedetta Terziroli Beretta-Piccoli, Guido Stirnimann, Andreas Cerny, David Semela, Roxane Hessler, Beat Helbling, Felix Stickel, Carolina Kalid-de Bakker, Florian Bihl, Emiliano Giostra, Magdalena Filipowicz Sinnreich, Carl Oneta, Adriana Baserga, Pietro Invernizzi, Marco Carbone, Joachim Mertens
No data on primary biliary cholangitis (PBC) are available in Switzerland. We established a national patient cohort to obtain information on PBC phenotypes and disease course in Switzerland. Local databases in all university hospitals and in two large secondary centers were searched for case finding. In addition, all primary care physicians, gastroenterologists, rheumatologists, and dermatologists were invited to contribute patients from their own medical records. PBC diagnosis was centrally reviewed. Five hundred one PBC patients were identified, 474 were included in data analysis, and 449 of them were enrolled by tertiary centers...
November 27, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29174547/living-like-an-academic-athlete-how-to-improve-clinical-and%C3%A2-academic-productivity-as-a-gastroenterologist
#16
Eric I Benchimol, Richard Keijzer
No abstract text is available yet for this article.
November 22, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29173303/are-we-using-abdominal-radiographs-appropriately-in-the-management-of-pediatric-constipation
#17
Beate Beinvogl, Sabina Sabharwal, Maireade McSweeney, Samuel Nurko
OBJECTIVE: To identify the reasons why pediatric gastroenterologists obtain abdominal radiographs in the management of pediatric constipation. STUDY DESIGN: This was a prospective study surveying providers regarding their rationale, interpretation, resultant change, and confidence in their management before and after obtaining KUBs in patients seen for suspected constipation. Demographics and clinical findings were obtained from medical records. RESULTS: A total of 24 providers were surveyed after 72 patient encounters...
December 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29165435/there-is-no-correlation-between-signs-of-reflux-laryngitis-and-reflux-oesophagitis-in-patients-with-gastro-oesophageal-reflux-disease-symptoms
#18
K Zelenik, I M Kajzrlikova, P Vitek, O Urban, M Hanousek, P Kominek
The objective of the present study was to determine if there is correlation between signs of reflux laryngitis (RL) and reflux oesophagitis (RE) in patients with gastro-oesophageal reflux disease (GORD) symptoms. Laryngeal photography obtained from patients during oesophagogastroduodenoscopy were examined by two otolaryngologists experienced in the field of extra-oesophageal reflux regarding the presence and severity of RL. The presence of RE was evaluated by gastroenterologist. Smokers, heavy drinkers and patients with bronchial asthma were excluded from the statistical analysis...
October 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29163962/chronic-anemia-due-to-gastrointestinal-bleeding-when-do-gastroenterologists-transfuse
#19
K V Grooteman, Ejm van Geenen, W Kievit, Jph Drenth
Background: The hypothesis is that decision-making for transfusion varies considerably among gastroenterologists. The aim is to identify preferences and predictors of transfusion decision-making in chronic anemia. Study design and methods: Between February and April of 2015, a computerized adaptive choice-based conjoint survey was administered to gastroenterologists in the Netherlands. The survey included seven patient attributes: hemoglobin levels, hemoglobin stability, age, iron indices, the presence of anemia-related symptoms, cardiovascular comorbidities, and the number of transfusions in the past half year...
November 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29159605/outcomes-of-emergency-laparotomy-el-care-protocol-at-tertiary-care-center-from-low-middle-income-country-lmic
#20
Nitin Vashistha, Dinesh Singhal, Sandeep Budhiraja, Bharat Aggarwal, Raj Tobin, Kamal Fotedar
BACKGROUND: Emergency laparotomy mortality ranges between 10 and 20% in best of Western healthcare systems and is currently a major focus for quality improvement programs. In contrast, emergency surgery scenario in LMIC is largely undefined, often neglected and complex (large burden of diseases but only limited capacity for adequate treatment). We evaluated the efficacy of 'EL care protocol' aimed at cost-effective optimal utilization of best available local expertise and infrastructure...
November 20, 2017: World Journal of Surgery
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