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https://www.readbyqxmd.com/read/29434428/evaluation-of-endovenous-laser-ablation-for-varicose-veins-using-a-computer-simulation-model-secondary-publication
#1
REVIEW
Hisanao Hazama, Masato Yoshimori, Norihiro Honda, Kunio Awazu
Background and aims: Endovenous laser ablation (EVLA) has been well-reported as a minimally invasive method to deal with varices of the lower extremities. The lasers used fall into two categories: pigment, i.e., hemoglobin-specific lasers in the visible and near-infrared (near-IR) wavebands and longer wavelength mid-infrared lasers where the chromophore is water. The fiber used to deliver the laser energy is also important, and not enough attention has been paid to this element of EVLA...
December 31, 2017: Laser Therapy
https://www.readbyqxmd.com/read/29429602/-characteristics-and-health-status-of-homeless-women-born-in-france-and-abroad-results-of-insee-ined-2012-survey
#2
M-E Gomes do Espirito Santo, A-L Perrine, C Bonaldi, I Guseva-Canu
BACKGROUND: French national surveys among the homeless population in 2001 and 2012 provided a general description of the homeless beneficiaries of medical and social aids. However, given the increasing number of women in this population, mostly born abroad and accompanied by their children, a descriptive study of homeless women according to the fact of being born in France or abroad was conducted. METHODS: A probability sample of 1470 French-speaking homeless women was recruited for the Insee-Ined 2012 survey...
February 8, 2018: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29401783/design-of-a-compact-cmos-compatible-photonic-antenna-by-topological-optimization
#3
Julián L Pita, Ivan Aldaya, Paulo Dainese, Hugo E Hernandez-Figueroa, Lucas H Gabrielli
Photonic antennas are critical in applications such as spectroscopy, photovoltaics, optical communications, holography, and sensors. In most of those applications, metallic antennas have been employed due to their reduced sizes. Nevertheless, compact metallic antennas suffer from high dissipative loss, wavelength-dependent radiation pattern, and they are difficult to integrate with CMOS technology. All-dielectric antennas have been proposed to overcome those disadvantages because, in contrast to metallic ones, they are CMOS-compatible, easier to integrate with typical silicon waveguides, and they generally present a broader wavelength range of operation...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29390960/a-high-throughput-screen-for-active-human-transposable-elements
#4
Erika M Kvikstad, Paolo Piazza, Jenny C Taylor, Gerton Lunter
BACKGROUND: Transposable elements (TEs) are mobile genetic sequences that randomly propagate within their host's genome. This mobility has the potential to affect gene transcription and cause disease. However, TEs are technically challenging to identify, which complicates efforts to assess the impact of TE insertions on disease. Here we present a targeted sequencing protocol and computational pipeline to identify polymorphic and novel TE insertions using next-generation sequencing: TE-NGS...
February 1, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29388061/clinical-impact-of-pi3k-braf-mutations-in-ras-wild-metastatic-colorectal-cancer-meta-analysis-results
#5
Amr Mohamed, Brandon Twardy, Nadine AbdAllah, Alaa Akhras, Hibah Ismail, Magdi Zordok, Kelly Schrapp, Taraq Attumi, Anteneh Tesfaye, Bassel El-Rayes
BACKGROUND: Understanding the molecular mechanisms of colorectal cancer has evolved during the last decade ushering the era of personalized medicine. Alteration of BRAF and PI3K is common in colorectal cancer, and can affect several signaling pathways including EGFR (epidermal growth factor receptor). The aim of this meta-analysis is to evaluate the clinical role of PI3K and BRAF mutations in patients with KRAS wild-type metastatic colorectal cancer (MCRC) receiving an EGFR monoclonal antibody (anti-EGFR) inhibitor as first-line therapy...
February 1, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29387324/development-and-validation-of-a-semi-quantitative-food-frequency-questionnaire-among-older-people-in-north-of-iran
#6
Ali Bijani, Haleh Esmaili, Reza Ghadimi, Atekeh Babazadeh, Reyhaneh Rezaei, Robert G Cumming, Seyed Reza Hosseini
Background: The study was conducted to assess reliability of modified semi-quantitative food frequency questionnaire (SQFFQ) as a part of the Amirkola Health and Aging Project (AHAP). Methods: The study was carried out in a sample of 200 men and women aged 60 years and older. A 138-item SQFFQ and two 24-hour dietary recalls were completed. The reliability of SQFFQ was evaluated by comparing eighteen food groups, energy and nutrient intakes derived from both methods using Spearman and Pearson's correlation coefficients for food groups and nutrients, respectively...
2018: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29377512/association-of-nrg1-and-auts2-genetic-polymorphisms-with-hirschsprung-disease-in-a-south-chinese-population
#7
Yan Zhang, Xiaoli Xie, Jixiao Zeng, Qiang Wu, Ruizhong Zhang, Deli Zhu, Huimin Xia
Hirschsprung disease (HSCR) is a genetic disorder characterized by the absence of enteric ganglia. There are more than 15 genes identified as contributed to HSCR by family-based or population-based approaches. However, these findings were not fulfilled to explain the heritability of most sporadic cases. In this study, using 1470 HSCR and 1473 control subjects in South Chinese population, we replicated two variants in NRG1 (rs16879552, P = 1.05E-04 and rs7835688, P = 1.19E-07), and further clarified the two replicated SNPs were more essential for patients with short-segment aganglionosis (SHSCR) (P = 2...
January 29, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29344220/overexpression-of-microrna-1470-promotes-proliferation-and-migration-and-inhibits-senescence-of-esophageal-squamous-carcinoma-cells
#8
Li-Li Mei, Yun-Tan Qiu, Wen-Jun Wang, Jie Bai, Zhi-Zhou Shi
MicroRNA-1470 (miR-1470) is overexpressed in esophageal squamous cell carcinoma (ESCC); however, its role and underlying molecular mechanism remain unknown. The aim of the present study was to explore the tumorigenic role and mechanism of miR-1470 overexpression in ESCC. The expression of miR-1470 in ESCC tissues and cell lines was detected using human miRNA microarrays and the reverse transcription-quantitative polymerase chain reaction, respectively. The effects of miR-1470 on cell proliferation, migration and senescence were determined using a Cell Counting Kit-8 assay, Transwell migration assay and β-galactosidase staining kit...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29326812/endovascular-laser-treatment-of-incompetent-saphenous-veins-using-the-1470-nm-diode-laser-and-radial-fiber
#9
Georgios Vourliotakis, Georgios Sahsamanis, Paschalis Evagelidis, Christina Aivatidi
Objectives: To assess the technical success, complications, and patients' quality of life (QoL) after treatment of chronic venous disease (CVD) using the 1470 nm radial fiber laser. Methods: A total of 170 patients with chronic venous disease, classified as C2 to C4 according to CEAP classification, were treated for incompetent greater (GSV) and small (SSV) saphenous veins, using the 1470 nm radial fiber laser and application of tumescent anesthesia. Additional phlebectomies were performed through stab microincisions, while 11 patients further underwent sclerotherapy intraoperatively...
January 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29323779/effect-of-different-liners-on-fracture-resistance-of-premolars-restored-with-conventional-and-short-fiber-reinforced-composite-resins
#10
Fereshteh Shafiei, Maryam Doozandeh, Dordaneh Ghaffaripour
PURPOSE: To see whether applying four different liners under short fiber-reinforced composite (SFRC), everX Posterior, compared to conventional composite resin, Z250, affected their strengthening property in premolar MOD cavities. MATERIALS AND METHODS: Mesio-occluso-distal (MOD) cavities were prepared in 120 sound maxillary premolars divided into 10 groups (n = 12) in terms of two composite resin types and 4 liners or no liner. For each composite resin, in 5 groups no liner, resin-modified glass ionomer (RMGI), conventional flowable composite (COFL), self-adhesive flowable composite resin (SAFL), and self-adhesive resin cement (SARC) were applied prior to restoring incrementally...
January 11, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29300986/healthcare-services-utilization-following-admission-for-hip-fracture-in-elderly-patients
#11
Ehud Fliss, Orly Weinstein, Michael Sherf, Jacob Dreiher
Objectives: To assess the effect of hip fracture on healthcare utilization among elderly patients. Design: Retrospective cohort study. Setting: Eight general hospitals in Israel, owned by Clalit. Participants: Enrollees >65 years, admitted with a hip fracture during 2009-2013. Main outcome measures: Data collected included demographics, comorbidities, admission details related to the surgical and rehabilitation hospitalizations, mortality and costs...
December 29, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29288635/foxd3-inhibits-scn2a-gene-transcription-in-intractable-epilepsy-cell-models
#12
Jun Xiang, Fang Wen, Lingyun Zhang, Yu Zhou
The expression of sodium voltage-gated channel alpha subunit 2 (SCN2A) is closely related to the development of epilepsy. This study investigated regulatory element of the SCN2A gene involved in epilepsy. An intractable epilepsy cell model was constructed using hippocampal primary neurons and the SH-SY5Y cell line. SCN2A protein and gene expression in cells as well as the level of lactic acid dehydrogenase (LDH) in the cell culture supernatants was detected. Potential regulatory factors of SCN2A and its upstream regulatory elements were identified using the dual-luciferase reporter assay...
December 28, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29284464/potential-use-of-telephone-based-survey-for-non-communicable-disease-surveillance-in-sri-lanka
#13
H M M Herath, N P Weerasinghe, T P Weerarathna, A Hemantha, A Amarathunga
BACKGROUND: Telephone survey (TS) has been a popular tool for conducting health surveys, particularly in developed countries. However, the feasibility, and reliability of TS are not adequately explored in Sri Lanka. The main aim of this study is to assess the effectiveness of telephone-based survey in estimating the prevalence of common non-communicable diseases (NCDs) in Sri Lanka. METHODS: We carried out an observational cross-sectional study using telephone interview method in Galle district, Sri Lanka...
December 29, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29274045/overwork-accelerates-thrombotic-reaction-implications-for-the-pathogenesis-of-karoshi
#14
Kazunori Otsui, Junichiro Yamamoto, Nobutaka Inoue
Work-related stressors are potential causes of cardiovascular diseases (CVDs) and stroke; however, the pathophysiological mechanisms by which occupational stress induces and exacerbates CVDs remain unclear. The global thrombosis test (GTT) is a novel in vitro assay for evaluating both thrombotic reactions and subsequent thrombolysis. The time required to form an occlusive thrombus with the GTT, called as the occlusion time (OT), and the time to lyse the thrombus, the lysis time (LT), are markers of thrombotic and thrombolytic reactions, respectively...
December 22, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29273876/surgeon-performed-endoscopic-retrograde-cholangiopancreatography-outcomes-of-2392-procedures-at-two-tertiary-care-centers
#15
Mazen R Al-Mansour, Eleanor C Fung, Edward L Jones, Nichole E Zayan, Timothy D Wetzel, Sara E Martin Del Campo, Anahita D Jalilvand, Andrew J Suzo, Rebecca R Dettorre, James K Fullerton, Michael P Meara, John D Mellinger, Vimal K Narula, Jeffrey W Hazey
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is a common procedure that, in the United States, is traditionally performed by gastroenterologists. We hypothesized that when performed by well-trained surgeons, ERCP can be performed safely and effectively. The objectives of the study were to assess the rate of successful cannulation of the duct of interest and to assess the 30-day complication and mortality rates. METHODS: We retrospectively reviewed the charts of 1858 patients who underwent 2392 ERCP procedures performed by five surgeons between August 2003 and June 2016 in two centers...
December 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29248107/prospective-comparative-cohort-study-evaluating-incompetent-great-saphenous-vein-closure-using-radiofrequency-powered-segmental-ablation-or-1470-nm-endovenous-laser-ablation-with-radial-tip-fibers-varico-2-study
#16
James A Lawson, Stefanie A Gauw, Clarissa J van Vlijmen, Pascal Pronk, Menno T W Gaastra, Marco J Tangelder, Michael C Mooij
BACKGROUND: Endovenous laser ablation (EVLA) and radiofrequency-powered segmental ablation (RPSA) of the incompetent great saphenous vein (GSV) are both known for their excellent technical and clinical outcomes for the treatment of varicose veins. RPSA has reduced postprocedural pain and morbidity with shorter recovery time for the patient compared with EVLA using bare-tip fibers. However, new-generation EVLA devices with less traumatic radial-tip fibers (RTFs) operating at longer wavelengths up to 1470 nm also reduce postprocedural pain...
January 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29186745/-laserhemorrhoidoplasty-with-1470%C3%A2-nm-diode-laser-in-the-treatment-of-second-to-fourth-degree-hemorrhoidal-disease-a-cohort-study-with-497-patients
#17
Guido Weyand, Claudia Susanne Theis, Aboubacar Nzambi Fofana, Felix Rüdiger, Thomas Gehrke
Background Laser haemorrhoidoplasty (LHP) with the 1470 nm diode laser in minimally invasive surgery for advanced haemorrhoid disease has been studied with respect to clinical variables, such as pain and complications, and intraoperative characteristics such as mucopexia, number of treated knots and energy consumed per patient. The study also included patient satisfaction, symptom relevance and cost effectiveness. Patients and Methods Between November 2010 and November 2016, 497 patients (age 55 ± 14 years) were submitted to laser haemorrhoidoplasty with a 1470 nm diode laser in the centre for minimally invasive proctology in Siegen District Hospital...
November 29, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29164454/postsurgical-sympathetic-ophthalmia-retrospective-analysis-of-a-rare-entity
#18
Parthopratim Dutta Majumder, Eliza Anthony, Amala Elizabeth George, Sudha K Ganesh, Jyotirmay Biswas
PURPOSE: To describe clinical manifestations, management and visual outcome in postsurgical sympathetic ophthalmia (SO). METHODS: Retrospective study. RESULTS: Mean age of the patients was 41.1 years, and males were affected 1.8 times than the female. Vitrectomy and scleral buckling were the most common inciting surgeries followed by cataract surgery. Among 10 eyes with anterior uveitis, mutton-fat keratic precipitate was seen in only two eyes...
November 21, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29156146/effectiveness-of-a-staged-us-and-unenhanced-mr-imaging-algorithm-in-the-diagnosis-of-pediatric-appendicitis
#19
Elizabeth H Dibble, David W Swenson, Claudia Cartagena, Grayson L Baird, Thaddeus W Herliczek
Purpose To establish, in a large cohort, the diagnostic performance of a staged algorithm involving ultrasonography (US) followed by conditional unenhanced magnetic resonance (MR) imaging for the imaging work-up of pediatric appendicitis. Materials and Methods A staged imaging algorithm in which US and unenhanced MR imaging were performed in pediatric patients suspected of having appendicitis was implemented at the authors' institution on January 1, 2011, with US as the initial modality followed by unenhanced MR imaging when US findings were equivocal...
November 20, 2017: Radiology
https://www.readbyqxmd.com/read/29133217/association-between-sleep-disturbance-and-new-onset-subjective-knee-pain-in-great-east-japan-earthquake-survivors-a-prospective-cohort-study-in-the-miyagi-prefecture
#20
Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Yutaka Yabe, Masashi Koide, Nobuyuki Itaya, Shinichiro Yoshida, Yasuhito Sogi, Masahiro Tsuchiya, Ichiro Tsuji, Eiji Itoi
BACKGROUND: The Great East Japan Earthquake (GEJE) and Tsunami devastated the northeastern coast of Japan on March 11, 2011. This study aimed to determine whether sociopsychological factors, such as sleep disturbance and psychological distress, influenced new-onset subjective knee pain in survivors during the post-disaster phase of the GEJE. METHODS: From November 2012 to February 2013 (2 years after the GEJE) and from November 2013 to February 2014 (3 years after the GEJE), survivors (≥18 years) completed self-reported questionnaires...
November 10, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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