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Pneumonia childhood

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https://www.readbyqxmd.com/read/27918383/etiology-of-acute-otitis-media-in-children-less-than-5-years-of-age-a-pooled-analysis-of-10-similarly-designed-observational-studies
#1
Melissa K Van Dyke, Jean-Yves Pirçon, Robert Cohen, Shabir A Madhi, Andrés Rosenblüt, Mercedes Macias Parra, Khalid Al-Mazrou, Gerhard Grevers, Pio Lopez, Laura Naranjo, Felix Pumarola, Nuntigar Sonsuwan, William P Hausdorff
BACKGROUND: Acute otitis media (AOM) is an important cause of childhood morbidity and antibiotic prescriptions. However, the relative importance of the well-known otopathogens, Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu), remains unclear due to a limited number of tympanocentesis-based studies that vary significantly in populations sampled, case definitions, and heptavalent pneumococcal conjugate vaccine (PCV7-CRM) use. METHODS: We conducted a pooled analysis of results from ten AOM etiology studies of similar design the protocols of which were derived from a common protocol and conducted in children 3 months to 5 years of age in different countries...
November 30, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27917707/management-of-pneumonia-in-the-pediatric-critical-care-unit-an-area-for-antimicrobial-stewardship
#2
Aimee M Dassner, David P Nicolau, Jennifer E Girotto
Pediatric pneumonia is one of the most common causes of childhood infection requiring hospitalization and is a substantial driver of antimicrobial use among hospitalized children. About 12-20% of pediatric patients hospitalized with community-acquired pneumonia (CAP) require critical care. Additionally, nosocomial pneumonias (i.e. hospital-acquired and ventilator-associated pneumonias) are responsible for 15-53% of hospital-associated infections and are the most common indication for empiric antibiotics in the pediatric intensive care unit...
December 4, 2016: Current Pediatric Reviews
https://www.readbyqxmd.com/read/27914588/obesity-in-pediatric-trauma
#3
Cordelie E Witt, Saman Arbabi, Avery B Nathens, Monica S Vavilala, Frederick P Rivara
BACKGROUND/PURPOSE: The implications of childhood obesity on pediatric trauma outcomes are not clearly established. Anthropomorphic data were recently added to the National Trauma Data Bank (NTDB) Research Datasets, enabling a large, multicenter evaluation of the effect of obesity on pediatric trauma patients. METHODS: Children ages 2 to 19years who required hospitalization for traumatic injury were identified in the 2013-2014 NTDB Research Datasets. Age and gender-specific body mass indices (BMI) were calculated...
November 23, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27903240/central-line-associated-bloodstream-infections-in-a-tertiary-care-children-s-university-hospital-a-prospective-study
#4
Elisabetta Venturini, Carlotta Montagnani, Alessandra Benni, Sabrina Becciani, Klaus Peter Biermann, Salvatore De Masi, Elena Chiappini, Maurizio de Martino, Luisa Galli
BACKGROUND: The central-line associated bloodstream infections (CLABSI) are the most common healthcare-associated infections in childhood. Despite the international data available on healthcare-associated infections in selected groups of patients, there is a lack of large and good quality studies. The present survey is the first prospective study monitoring for 6 months the occurrence of central-line associated bloodstream infections in all departments of an Italian tertiary care children's university hospital...
December 1, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27899204/stevens-johnson-syndrome-in-childhood
#5
N Blanco, B Gutiérrez, I Valls, D Puertas, C Martín, M Rivera, Á Hernández, A Torrelo
INTRODUCTION: Stevens-Johnson syndrome and toxic epidermal necrolysis are two serious immune diseases within the context of bullous mucocutaneous syndrome. These have varying degrees of involvement of the skin and usually at least two mucous membranes. CLINICAL CASES: Three clinical cases are presented, two of them with significant ophthalmological sequelae, who had received drug treatment as a possible trigger, and another milder clinical case caused by Mycoplasma pneumoniae...
November 26, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27889731/comparison-of-lung-ultrasonography-and-chest-radiography-for-diagnosis-of-childhood-pneumonia-pediatric-emergency-medicine-physicians-viewpoint
#6
Sathyaseelan Subramaniam, Jennifer H Chao
No abstract text is available yet for this article.
November 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27889730/comparison-of-lung-ultrasonography-and-chest-radiography-for-diagnosis-of-childhood-pneumonia-evidence-based-medicine-viewpoint
#7
Joseph L Mathew
No abstract text is available yet for this article.
November 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27882866/the-performance-of-community-health-workers-in-the-management-of-multiple-childhood-infectious-diseases-in-lira-northern-uganda-a-mixed-methods-cross-sectional-study
#8
Phillip Wanduru, Moses Tetui, Doreen Tuhebwe, Michael Ediau, Monica Okuga, Christine Nalwadda, Elizabeth Ekirapa-Kiracho, Peter Waiswa, Elizeus Rutebemberwa
BACKGROUND: Community health workers (CHWs) have the potential to reduce child mortality by improving access to care, especially in remote areas. Uganda has one of the highest child mortality rates globally. Moreover, rural areas bear the highest proportion of this burden. The optimal performance of CHWs is critical. In this study, we assess the performance of CHWs in managing malaria, pneumonia, and diarrhea in the rural district of Lira, in northern Uganda. DESIGNS: A cross-sectional mixed methods study was undertaken to investigate the performance of 393 eligible CHWs in the Lira district of Uganda...
2016: Global Health Action
https://www.readbyqxmd.com/read/27880051/multimorbidities-of-asthma-allergies-and-airway-illnesses-in-childhood-chance-or-not-chance
#9
Wei Liu, Chen Huang, Xueying Wang, Jiao Cai, Yu Hu, Zhijun Zou, Louise B Weschler, Li Shen, Jan Sundell
OBJECTIVES: We investigated patterns of multimorbidities among asthma, allergies, and respiratory illnesses in preschool children. We examined lifetime multimorbidities of asthma, allergic rhinitis, eczema, food allergy, pneumonia, and ear infections; and current (in the last year before the survey) multimorbidities of wheeze, dry cough, rhinitis, eczema, and common cold during childhood. We further analyzed whether prevalences of these multimorbidities were due to chance. METHODS: A cross-sectional study was conducted in 72 kindergartens of Shanghai, China...
November 23, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27863648/biodegradable-airway-stents-in-infants-potential-life-threatening-pitfalls
#10
B Sztanó, G Kiss, K Márai, G Rácz, I Szegesdi, K Rácz, G Katona, L Rovó
OBJECTIVE: The solution of severe tracheobronchial obstructions in early childhood means a great challenge. Biodegradable stents were intended to be a minimally invasive temporary solution which may decrease the number of interventions and limit the possible complications of stenting procedures. However, our first experiences have brought out a new, - especially in childhood - potentially life-threatening complication of this concept. METHODS: Five SX-ELLA biodegradable polydioxanone stents was applied in three patients because of severe tracheobronchial obstruction: congenital tracheomalacia (7 day-old), acquired tracheomalacia (10 month-old), and congenital trachea-bronchomalacia (10 month-old)...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27855688/fatal-varicella-pneumonia-in-an-unvaccinated-child-with-down-syndrome-a-case-report
#11
Diletta Valentini, Simona Bianchi, Chiara Di Camillo, Anna Chiara Vittucci, Michaela Veronika Gonfiantini, Rita De Vito, Alberto Villani
BACKGROUND: Varicella is an acute infectious disease common during childhood. It has mostly an uncomplicated course in early childhood. Neverthless, it may result in severe complications, especially in particular age groups and clinical conditions. Down Syndrome represents a risk factor for developing complications, because of the frequent comorbidities and their immunodeficiency. CASE PRESENTATION: A 2-year-old white Caucasian female affected by Down Syndrome was referred to our hospital for cardiac arrest in course of varicella disease...
November 17, 2016: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/27846837/prevalence-aetiology-treatment-and-outcomes-of-shock-in-children-admitted-to-kenyan-hospitals
#12
George Mbevi, Philip Ayieko, Grace Irimu, Samuel Akech, Mike English
BACKGROUND: Shock may complicate several acute childhood illnesses in hospitals within low-income countries and has a high case fatality. Hypovolemic shock secondary to diarrhoea/dehydration and septic shock are thought to be common, but there are few reliable data on prevalence or treatment that differ for the two major forms of shock. Examining prevalence and treatment practices has become important since reports suggest high risks from liberal use of fluid boluses in African children...
November 16, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27843130/reduction-of-childhood-pneumonia-mortality-in-the-sustainable-development-era
#13
Eric D McCollum, Carina King, Laura L Hammitt, Amy S Ginsburg, Tim Colbourn, Abdullah H Baqui, Katherine L O'Brien
No abstract text is available yet for this article.
November 11, 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27806810/childhood-acute-bacterial-meningitis-clinical-spectrum-bacteriological-profile-and-outcome
#14
Attia Bari, Fatima Zeeshan, Aiza Zafar, Hassan Ejaz, Aisha Iftikhar, Ahsan Waheed Rathore
OBJECTIVE: To determine the disease pattern, etiological agents and outcome of childhood acute bacterial meningitis. STUDY DESIGN: Adescriptive study. PLACE AND DURATION OF STUDY: Department of Paediatric Medicine, The Children's Hospital, Lahore, from January to December 2012. METHODOLOGY: Atotal of 199 children between the ages of 1 month and 5 years, admitted with the diagnosis of meningitis on the basis of clinical findings and positive cerebrospinal fluid (CSF), were included...
October 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27790628/factors-associated-with-pneumonia-among-overweight-and-obese-under-five-children-in-an-urban-hospital-of-a-developing-country
#15
K M Shahunja, Tahmeed Ahmed, Md Iqbal Hossain, Sumon Kumar Das, Abu Syeed Golam Faruque, Md Munirul Islam, Abu Sadat Mohammad Sayeem Bin Shahid, Jui Das, Mohammad Habibur Rahman Sarker, Mohammod Jobayer Chisti
To our knowledge, there are no data on the role of overweight and obesity in childhood pneumonia. We sought to determine that impact of overweight and obesity in such children. In this retrospective chart analysis, we enrolled hospitalized children aged 6 to 59 months in the Dhaka Hospital of the icddr,b, Bangladesh (International Centre for Diarrhoeal Disease Research, Bangladesh), from January 2010 to June 2014. Children with pneumonia having overweight and obesity (body mass index Z score [BMIZ] >2.00) constituted cases (n = 25), and those who had pneumonia without overweight and obesity (BMIZ -2...
2016: Global Pediatric Health
https://www.readbyqxmd.com/read/27788179/mpneumonia-an-innovation-for-diagnosing-and-treating-childhood-pneumonia-in-low-resource-settings-a-feasibility-usability-and-acceptability-study-in-ghana
#16
Amy Sarah Ginsburg, Charlotte Tawiah Agyemang, Gwen Ambler, Jaclyn Delarosa, Waylon Brunette, Shahar Levari, Clarice Larson, Mitch Sundt, Sam Newton, Gaetano Borriello, Richard Anderson
Pneumonia is the leading cause of infectious disease mortality in children. Currently, health care providers (HCPs) are trained to use World Health Organization Integrated Management of Childhood Illness (IMCI) paper-based protocols and manually assess respiratory rate to diagnose pneumonia in low-resource settings (LRS). However, this approach of relying on clinical signs alone has proven problematic. Hypoxemia, a diagnostic indicator of pneumonia severity associated with an increased risk of death, is not assessed because pulse oximetry is often not available in LRS...
2016: PloS One
https://www.readbyqxmd.com/read/27779714/whole-exome-sequencing-identification-of-novel-dnah5-mutations-in-a-young-patient-with-primary-ciliary-dyskinesia
#17
Gen Kano, Hisashi Tsujii, Kazuhiko Takeuchi, Kaname Nakatani, Makoto Ikejiri, Satoru Ogawa, Hisami Kubo, Mizuho Nagao, Takao Fujisawa
Primary ciliary dyskinesia (PCD) is a rare genetic disorder caused by structural and/or functional impairment of cilia throughout the whole body. Early diagnosis of PCD is important for the prevention of long‑term sequelae, however early diagnosis is a challenge due to the phenotypic heterogeneity of PCD. In the current study, the patient with PCD was diagnosed at nine years old following several efforts to control intractable airway symptoms. The patient experienced a chronic productive cough beginning in early childhood and had multiple episodes of pneumonia and otitis media with effusion and sinusitis...
October 21, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27771185/role-of-antibodies-and-il17-mediated-immunity-in-protection-against-pneumococcal-otitis-media
#18
Marrit N Habets, Saskia van Selm, Fred J van Opzeeland, Elles Simonetti, Peter W M Hermans, Marien I de Jonge, Dimitri A Diavatopoulos
Widespread vaccination against Streptococcus pneumoniae (the pneumococcus) has significantly reduced pneumococcal disease caused by vaccine serotypes. Despite vaccination, overall pneumococcal colonization rates in children have not reduced and otitis media (OM) by non-vaccine serotypes remains one of the most common childhood infections. Pneumococcal surface protein A (PspA) has been shown to be a promising protein antigen to induce broad protection against pneumococcal colonization. However, its ability to protect against OM remains unclear...
October 19, 2016: Vaccine
https://www.readbyqxmd.com/read/27765020/demographic-and-mortality-analysis-of-hospitalized-children-at-a-referral-hospital-in-addis-ababa-ethiopia
#19
J A Bohn, B M Kassaye, D Record, B C Chou, I L Kraft, J C Purdy, K A Hilton, D A Miller, S Getachew, A Addissie, J A Robison
BACKGROUND: Global childhood mortality rates remain high. Millennium Development Goal 4 focused efforts on reducing rates by two-thirds between 1990 and 2015. In Ethiopia, child mortality rates dropped 71 % from 1990 to 2015, however it is estimated that 184,000 Ethiopian children die each year. There is limited information about pediatric hospital admissions in Ethiopia. Our aims were to examine the temporal relationship of mortality to admission, describe the demographics, and identify cause mortality of children admitted to the Zewditu Memorial Hospital (ZMH)...
October 21, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27761288/a-case-of-biotinidase-deficiency-in-an-adult-with-respiratory-failure-in-the-intensive-care-unit
#20
Zerrin Demirtürk, Evren Şentürk, Abbas Köse, Perihan Ergin Özcan, Lütfi Telci
BACKGROUND: Biotinidase deficiency (BD) is a rare, inherited autosomal recessive disorder that is treatable within childhood. We present a patient with pneumonia and respiratory acidosis who was not diagnosed with any systemic disorders; the patient was finally diagnosed as BD. CASE REPORT: A thirty-year-old woman was admitted to the emergency department with respiratory failure that had persisted for a few days and progressively weakening over the previous six months...
September 2016: Balkan Medical Journal
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