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Pneumonia childhood

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https://www.readbyqxmd.com/read/29333842/an-adolescent-with-idiopathic-pleuroparenchymal-fibroelastosis-case-report
#1
Emine Atag, Nilay Bas Ikizoglu, Yasemin Gokdemir, Ela Erdem Eralp, Gursu Kiyan, Dilek Yilmazbayhan, Bulent Karadag
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a rare disorder recently included in rare idiopathic interstitial pneumonias according to the updated American Thoracic Society/European Respiratory Society classification. IPPFE is characterized by pleural and subpleural parenchymal fibrosis causing volume loss predominantly in the upper lung lobes. Age of onset is variable, IPPFE mainly occurs in third and fourth decades. We present a 16 year old patient with a 2-year history of exertional dyspnea, nonproductive cough and weight loss...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29313476/serotype-distribution-of-clinical-streptococcus-pneumoniae-isolates-before-the-introduction-of-the-13-valent-pneumococcal-conjugate-vaccine-in-cambodia
#2
Malin Inghammar, Youlet By, Christina Farris, Thong Phe, Laurence Borand, Alexandra Kerleguer, Sophie Goyet, Vonthanak Saphonn, Chanleakhena Phoeung, Sirenda Vong, Blandine Rammaert, Charles Mayaud, Bertrand Guillard, Chadwick Yasuda, Matthew R Kasper, Gavin Ford, Steven W Newell, Ung Sam An, Buth Sokhal, Sok Touch, Paul Turner, Jan Jacobs, Mélina Messaoudi, Florence Komurian-Pradel, Arnaud Tarantola
Childhood vaccination with the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in Cambodia in January 2015. Baseline data regarding circulating serotypes are scarce. All microbiology laboratories in Cambodia were contacted for identification of stored isolates of Streptococcus pneumoniae from clinical specimens taken before the introduction of PCV13. Available isolates were serotyped using a multiplex polymerase chain reaction method. Among 166 identified isolates available for serotyping from patients with pneumococcal disease, 4% were isolated from upper respiratory samples and 80% were from lower respiratory samples, and 16% were invasive isolates...
January 8, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29302520/care-seeking-for-childhood-pneumonia-by-rural-and-poor-urban-communities-in-lucknow-a-community-based-cross-sectional-study
#3
Anurag Minz, Monika Agarwal, J V Singh, V K Singh
Context: Globally, around 16% of under-five children die due to pneumonia. Childhood pneumonia, if identified early is a readily treatable through low-cost antibiotics. Access to timely and appropriate care is a key action to control pneumonia. Aims: The aim of the study was to understand the caregiver's care-seeking behavior for the management of childhood pneumonia among rural and urban poor communities in Lucknow. Settings and Design: Rural areas and urban slums of Lucknow district, from September 2014 to August 2015...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29289943/pneumonia-diagnosis-in-childhood-and-incidence-of-leukaemia-lymphoma-and-brain-cancer-a-danish-nationwide-cohort-study
#4
Kirstine Kobberøe Søgaard, Dóra Körmendiné Farkas, Henrik Toft Sørensen
OBJECTIVES: There is an ongoing debate on the possible association between infections in early childhood and subsequent cancer risk, but it remains unclear if a hospital admission for infection is associated with risk of childhood cancer diagnosis. We examined if a hospital-based diagnosis of pneumonia was a clinical marker of the three most common childhood cancers. DESIGN: Population-based cohort study. SETTING: Denmark, hospital diagnoses, 1994-2013...
December 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/29284418/the-aetiologies-of-central-nervous-system-infections-in-hospitalised-cambodian-children
#5
Paul Turner, Kuong Suy, Le Van Tan, Pora Sar, Thyl Miliya, Nguyen Thi Thu Hong, Vu Thi Ty Hang, Nguyen Thi Han Ny, Sona Soeng, Nicholas P J Day, H Rogier van Doorn, Claudia Turner
BACKGROUND: Central nervous system (CNS) infections are an important cause of childhood morbidity and mortality. The aetiologies of these potentially vaccine-preventable infections have not been well established in Cambodia. METHODS: We did a one year prospective study of children hospitalised with suspected CNS infection at Angkor Hospital for Children, Siem Reap. Cerebrospinal fluid specimens (CSF) samples underwent culture, multiplex PCR and serological analysis to identify a range of bacterial and viral pathogens...
December 29, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29278609/mycoplasma-induced-rash-and-mucositis-in-a-father-and-son-a-case-report
#6
Hannah Song, Jennifer T Huang, Jennifer K Tan
This case report describes a father and son with recurrent Mycoplasma-induced rash and mucositis (MIRM). A father with a remote history of a similar rash in childhood presented to the hospital with a severe rash with mucosal involvement, and elevated Mycoplasma pneumoniae IgM titers, consistent with MIRM. Four years later, his son also developed a similar rash with a positive Mycoplasma pneumoniae polymerase chain reaction assay, which was consistent with MIRM. His course was complicated by recurrence of disease shortly after discharge from the hospital...
December 22, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29258745/recovery-from-childhood-community-acquired-pneumonia-in-a-developing-country-prognostic-value-of-serum-procalcitonin
#7
Taiane S Fonseca, Ângela G Vasconcellos, Dominique Gendrel, Olli Ruuskanen, Cristiana M Nascimento-Carvalho
BACKGROUND: Childhood community-acquired pneumonia is a common and potentially life-threatening illness in developing countries. We assessed the prognostic value of serum procalcitonin level upon admission on clinical response to antibiotic treatment. METHODS: Out of 89 patients, the median (IQR) age was 19(12-29) months and 60% were boys. Viral (49.5%), typical bacterial (38%) and atypical bacterial (12.5%) infections as well as probable pneumococcal infections (26%) were diagnosed...
December 16, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29248621/asthma-is-a-risk-factor-for-respiratory-exacerbations-without-increased-rate-of-lung-function-decline-five-year-follow-up-in-adult-smokers-from-the-copdgene-study
#8
Lystra P Hayden, Megan E Hardin, Weiliang Qiu, David A Lynch, Matthew J Strand, Edwin J van Beek, James D Crapo, Edwin K Silverman, Craig P Hersh
BACKGROUND: Previous investigations in adult smokers from the COPDGene Study have shown that early-life respiratory disease is associated with reduced lung function, COPD, and airway thickening. Using five-year follow-up data we assessed disease progression in subjects with early-life respiratory disease. We hypothesized that there are alternative pathways to reaching reduced FEV1 and subjects with childhood pneumonia, childhood asthma, or asthma-COPD overlap (ACO), would have less lung function decline than subjects without these conditions...
December 14, 2017: Chest
https://www.readbyqxmd.com/read/29241620/trends-in-and-projections-of-indicators-of-universal-health-coverage-in-bangladesh-1995-2030-a-bayesian-analysis-of-population-based-household-data
#9
Md Shafiur Rahman, Md Mizanur Rahman, Stuart Gilmour, Khin Thet Swe, Sarah Krull Abe, Kenji Shibuya
BACKGROUND: Many countries are implementing health system reforms to achieve universal health coverage (UHC) by 2030. To understand the progress towards UHC in Bangladesh, we estimated trends in indicators of the health service and of financial risk protection. We also estimated the probability of Bangladesh's achieving of UHC targets of 80% essential health-service coverage and 100% financial risk protection by 2030. METHODS: We estimated the coverage of UHC indicators-13 prevention indicators and four treatment indicators-from 19 nationally representative population-based household surveys done in Bangladesh from Jan 1, 1991, to Dec 31, 2014...
January 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29241619/problems-with-the-who-guidelines-for-management-of-childhood-pneumonia
#10
Kim Mulholland
No abstract text is available yet for this article.
January 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29241618/appropriateness-of-clinical-severity-classification-of-new-who-childhood-pneumonia-guidance-a-multi-hospital-retrospective-cohort-study
#11
Ambrose Agweyu, Richard J Lilford, Mike English
BACKGROUND: Management of pneumonia in many low-income and middle-income countries is based on WHO guidelines that classify children according to clinical signs that define thresholds of risk. We aimed to establish whether some children categorised as eligible for outpatient treatment might have a risk of death warranting their treatment in hospital. METHODS: We did a retrospective cohort study of children aged 2-59 months admitted to one of 14 hospitals in Kenya with pneumonia between March 1, 2014, and Feb 29, 2016, before revised WHO pneumonia guidelines were adopted in the country...
January 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29237494/adherence-to-the-integrated-management-of-childhood-illness-guidelines-in-namibia-kenya-tanzania-and-uganda-evidence-from-the-national-service-provision-assessment-surveys
#12
Carsten Krüger, Monika Heinzel-Gutenbrunner, Mohammed Ali
BACKGROUND: Integrated Management of Childhood Illness (IMCI) is regarded as a standard public health approach to lowering child mortality in developing countries. However, little is known about how health workers adhere to the guidelines at the national level in sub-Saharan African countries. METHODS: Data from the Service Provision Assessment surveys of Namibia (NA) (survey year: 2009), Kenya (KE) (2010), Tanzania (TZ) (2006) and Uganda (UG) (2007) were analysed for adherence to the IMCI guidelines by health workers...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29226176/holistic-segmentation-of-the-lung-in-cine-mri
#13
William Kovacs, Nathan Hsieh, Holger Roth, Chioma Nnamdi-Emeratom, W Patricia Bandettini, Andrew Arai, Ami Mankodi, Ronald M Summers, Jianhua Yao
Duchenne muscular dystrophy (DMD) is a childhood-onset neuromuscular disease that results in the degeneration of muscle, starting in the extremities, before progressing to more vital areas, such as the lungs. Respiratory failure and pneumonia due to respiratory muscle weakness lead to hospitalization and early mortality. However, tracking the disease in this region can be difficult, as current methods are based on breathing tests and are incapable of distinguishing between muscle involvements. Cine MRI scans give insight into respiratory muscle movements, but the images suffer due to low spatial resolution and poor signal-to-noise ratio...
October 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29219259/nursing-management-of-childhood-chickenpox-infection
#14
Grace Boyd, Paul Anthony Heaton, Rachel Wilkinson, Siba Prosad Paul
Chickenpox is an extremely contagious infectious disease caused by varicella zoster virus (VZV). It is a common childhood illness characterised by an itchy vesicular rash and fever, which usually resolves spontaneously without medical intervention. Serious, and rarely fatal, complications can occur, including pneumonia, central nervous system infection, overwhelming secondary bacterial infections, especially with Group A streptococcus, and necrotising fasciitis. Therefore it is crucial that emergency department (ED) nurses can recognise the signs and symptoms that indicate deterioration...
December 8, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/29198820/resveratrol-improves-efficacy-of-oral-amoxicillin-against-childhood-fast-breathing-pneumonia-in-a-randomized-placebo-controlled-double-blind-clinical-trial
#15
Li Qiang, Yunfei Di, Zhilan Jiang, Juanjuan Xu
Childhood pneumonia has been considered as a major cause of child morbidity and mortality worldwide. We aimed to investigate the effect of resveratral in synergizing with oral amoxicillin to improve the treatment outcome of oral amoxicillin administration against childhood fast breathing pneumonia. 647 children diagnosed fast breathing pneumonia were recruited and randomized to receive oral amoxicillin plus either resveratrol (AX + RV) or placebo (AX + placebo). The primary outcome was defined as treatment failure up to day 3, while the secondary outcome was defined as treatment failure at day 6 and 12 upon follow up...
November 30, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29198542/kawasaki-disease-substantially-impacts-health-related-quality-of-life
#16
Soultana Kourtidou, April E Slee, Margaret E Bruce, Haaland Wren, Rita M Mangione-Smith, Michael A Portman
OBJECTIVE: To prospectively evaluate the acute impact of Kawasaki disease (KD) on health-related quality of life (HRQoL) and to assess deterioration in the HRQoL experienced by children with KD compared with other childhood diseases. STUDY DESIGN: We merged the Outcomes Assessment Program database obtained prospectively with the existing KD database and queried for KD admissions between 1 month and 13 years of age. HRQoL was evaluated with the parent-proxy Pediatric Quality of Life Inventory (PedsQL) 4...
November 30, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29192574/-a-woman-with-skin-rash-and-dyspnoea
#17
J L J Hanssen, N M Delfos
We present a 36-year-old woman who was born and raised in Hongkong but currently lived in the Netherlands. She was admitted with a varicella-zoster virus (VZV) primo-infection complicated by pneumonia and hepatitis. The patient was successfully treated with aciclovir. Adult VZV primo-infections are uncommon in Dutch natives but occur more often in immigrants from countries with a temperate climate where less people are infected during childhood.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29187536/inflammasome-antagonism-by-human-parainfluenza-virus-type-3-c-protein
#18
Niraj K Shil, Swechha M Pokharel, Amiya K Banerjee, Michael Hoffman, Santanu Bose
Human parainfluenza virus type 3 (HPIV3) is a negative-sense single-stranded RNA virus belonging to the paramyxoviridae family. HPIV3 is a lung tropic virus causing airway diseases including pneumonia, croup, and bronchiolitis during infancy and childhood. Activation of inflammasome by pathogens results in production of pro-inflammatory cytokines like IL-1β during infection. Thus, inflammasome mediated pro-inflammatory response plays a critical role in regulating immune response and virus clearance. Inflammasome is a multimeric protein complex triggering caspase-1 activation...
November 29, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29184760/rhabdomyolysis-with-different-etiologies-in-childhood
#19
Demet Alaygut, Meral Torun Bayram, Belde Kasap, Alper Soylu, Mehmet Türkmen, Salih Kavukcu
AIM: To investigate different etiologies and management of the rhabdomyolysis in children. METHODS: Eight pediatric rhabdomyolysis cases who applied to the Dokuz Eylul University Faculty of Medicine Department of Pediatric Nephrology with different etiologies between January 2004 and January 2012 were evaluated in terms of age, gender, admission symptoms, physical examination findings, factors provoking rhabdomyolysis, number of rhabdomyolysis attacks, laboratory results, family history and the final diagnosis received after the treatment...
November 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/29182949/modeling-the-potential-health-benefits-of-lower-household-air-pollution-after-a-hypothetical-liquified-petroleum-gas-lpg-cookstove-intervention
#20
Kyle Steenland, Ajay Pillarisetti, Miles Kirby, Jennifer Peel, Maggie Clark, Will Checkley, Howard H Chang, Thomas Clasen
INTRODUCTION: Improved biomass and advanced fuel cookstoves can lower household air pollution (HAP), but levels of fine particulate matter (PM2.5) often remain above the World Health Organization (WHO) recommended interim target of 35μg/m3. METHODS: Based on existing literature, we first estimate a range of likely levels of personal PM2.5 before and after a liquefied petroleum gas (LPG) intervention. Using simulations reflecting uncertainty in both the exposure estimates and exposure-response coefficients, we estimate corresponding expected health benefits for systolic blood pressure (SBP) in adults, birthweight, and pneumonia incidence among children <2years old...
November 25, 2017: Environment International
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