keyword
https://read.qxmd.com/read/38536594/pathologic-maternal-and-neonatal-outcomes-associated-with-programmed-embryo-transfer
#21
REVIEW
Kirk P Conrad, Frauke von Versen-Höynck, Valerie L Baker
PURPOSE: In this first of two companion papers, we critically review the evidence recently published in the primary literature, which addresses adverse maternal and neonatal pregnancy outcomes associated with programmed embryo transfer cycles. We next consider whether these pathological pregnancy outcomes might be attributable to traditional risk factors, unknown parental factors, embryo culture, culture duration, or cryopreservation. Finally, in the second companion article, we explore potential etiologies and suggest strategies for prevention...
March 27, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38536575/ethnic-inequities-in-use-of-breast-conserving-surgery-and-radiation-therapy-in-aotearoa-new-zealand-which-factors-contribute
#22
JOURNAL ARTICLE
Leah Boyle, Ross Lawrenson, Vili Nosa, Ian Campbell, Sandar Tin Tin
PURPOSE: Aotearoa/New Zealand (NZ) faces ethnic inequities with respect to breast cancer survival and treatment. This study establishes if there are ethnic differences in (i) type of surgery and (ii) receipt of radiotherapy (RT) following breast conserving surgery (BCS), among women with early-stage breast cancer in NZ. METHODS: This analysis used Te Rēhita Mata Ūtaetae (Breast Cancer Foundation National Register), a prospectively maintained database of breast cancers from 2000 to 2020...
March 27, 2024: Breast Cancer Research and Treatment
https://read.qxmd.com/read/38536536/what-keeps-the-style-under-tension-experimental-tests-to-understand-the-biomechanics-of-the-explosive-style-movement-in-marantaceae
#23
JOURNAL ARTICLE
Marcus Jerominek, Regine Claßen-Bockhoff
Pollination in Marantaceae is mediated by an explosive style movement. Before release, style tension is held by the hooded staminode. When a pollinator touches the trigger appendage of the hooded staminode the latter deforms and the style rapidly curls upwards. This movement has been interpreted as a turgor movement by some authors, but recent studies clearly indicate that setup, hold and release of tension are purely mechanical processes. However, in view of the high diversity of hooded staminodes, the question arises what keeps the tension in species with very thin staminodes...
March 27, 2024: Journal of Plant Research
https://read.qxmd.com/read/38536531/minimally-invasive-approaches-to-diagnose-and-monitor-eosinophilic-gi-diseases
#24
REVIEW
Ellie J M Furuta, Glenn T Furuta, Robin Shandas
PURPOSE OF REVIEW: This review seeks to understand novel avenues for eosinophilic GI disease management. Biomarkers offer a unique and non-invasive approach to tracking EoE disease progression. While no biomarkers have definitively met the diagnostic criteria for eosinophilic GI diseases, some biomarkers have been shown to be associated with disease activity. Here, we examine the potential of recently studied biomarkers. RECENT FINDINGS: Current research shows advancements in blood, luminal fluid, and breath testing...
March 27, 2024: Current Allergy and Asthma Reports
https://read.qxmd.com/read/38536512/potential-role-of-immune-cell-therapy-in-gynecological-cancer-and-future-promises-a-comprehensive-review
#25
REVIEW
Sandipan Dasgupta, Sakuntala Gayen, Tania Chakraborty, Naureen Afrose, Ranita Pal, Sutapa Mahata, Vilas Nasare, Souvik Roy
Gynecological malignancies are most leading causes of death among women worldwide. The high prevalence of gynecologic malignancies remains significant, necessitating to turn the novel treatment approach like immunotherapy, wherein cancer cells are killed by the invasion of immune system. In recent year, immunotherapy has mostly an advanced treatment approach to repressing the tumor cells survival, proliferation, and invasion via the activation of immune systems. Moreover, various types of immune cells including T-cells, B-cells, and dendritic cells are associated with the immunotherapeutic strategy in cancer treatment...
March 27, 2024: Medical Oncology
https://read.qxmd.com/read/38536500/the-interactions-of-subcellular-organelles-in-pulmonary-fibrosis-induced-by-carbon-black-nanoparticles-a-comprehensive-review
#26
REVIEW
Lei Bao, Qingping Liu, Jingyuan Wang, Lili Shi, Yaxian Pang, Yujie Niu, Rong Zhang
Owing to the widespread use and improper emissions of carbon black nanoparticles (CBNPs), the adverse effects of CBNPs on human health have attracted much attention. In toxicological research, carbon black is frequently utilized as a negative control because of its low toxicity and poor solubility. However, recent studies have indicated that inhalation exposure to CBNPs could be a risk factor for severe and prolonged pulmonary inflammation and fibrosis. At present, the pathogenesis of pulmonary fibrosis induced by CBNPs is still not fully elucidated, but it is known that with small particle size and large surface area, CBNPs are more easily ingested by cells, leading to organelle damage and abnormal interactions between organelles...
March 27, 2024: Archives of Toxicology
https://read.qxmd.com/read/38536476/herombopag-for-the-treatment-of-persistent-thrombocytopenia-following-hematopoietic-stem-cell-transplantation
#27
JOURNAL ARTICLE
Miao Zhou, Tongyu Li, Ping Zhang, Yanli Lai, Lixia Sheng, Guifang Ouyang
Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) stands as a pivotal treatment for hematologic malignancies, often considered the sole effective treatment option. A frequent complication following allo-HSCT is poor graft function (PGF), with one of its primary manifestations being persistent thrombocytopenia (PT), comprising prolonged isolated thrombocytopenia (PIT) and secondary failure of platelet recovery (SFPR). Conventional treatment methods have had poor efficacy and a high transplantation-associated mortality rate...
March 27, 2024: Annals of Hematology
https://read.qxmd.com/read/38536455/matching-proposed-clinical-and-mri-criteria-of-aggressive-multiple-sclerosis-to-serum-and-cerebrospinal-fluid-markers-of-neuroaxonal-and-glial-injury
#28
JOURNAL ARTICLE
Martin A Schaller-Paule, Michelle Maiworm, Jan Hendrik Schäfer, Lucie Friedauer, Elke Hattingen, Katharina Johanna Wenger, Frank Weber, Jasmin Jakob, Falk Steffen, Stefan Bittner, Yavor Yalachkov, Christian Foerch
BACKGROUND: Definitions of aggressive MS employ clinical and MR imaging criteria to identify highly active, rapidly progressing disease courses. However, the degree of overlap between clinical and radiological parameters and biochemical markers of CNS injury is not fully understood. Aim of this cross-sectional study was to match clinical and MR imaging hallmarks of aggressive MS to serum/CSF markers of neuroaxonal and astroglial injury (neurofilament light chain (sNfL, cNfL), and glial fibrillary acidic protein (sGFAP, cGFAP))...
March 27, 2024: Journal of Neurology
https://read.qxmd.com/read/38536390/co2-photoreduction-over-semiconducting-2d-materials-with-supported-single-atoms-recent-progress-and-challenges
#29
JOURNAL ARTICLE
Zhangben Dai, Kejun Yang, Tianyi Yang, Yalin Guo, Jianfeng Huang
In the face of the growing energy crisis and environmental challenges, substantial efforts are now directed toward sustainable clean energy as a replacement for traditional fossil fuels. CO2 photoreduction into value-added chemicals and fuels is widely recognized as a promising approach to mitigate current energy and environmental concerns. Photocatalysts comprising single atoms (SAs) supported on two-dimensional (2D) semiconducting materials (SAs-2DSemi) have emerged as a novel frontier due to the combined merits of SA catalysts and 2D materials...
March 27, 2024: Chemistry: a European Journal
https://read.qxmd.com/read/38536216/virulence-genes-resistome-and-mobilome-of-streptococcus-suis-strains-isolated-in-france
#30
JOURNAL ARTICLE
Manon Dechêne-Tempier, Claire de Boisséson, Pierrick Lucas, Stéphanie Bougeard, Virginie Libante, Corinne Marois-Créhan, Sophie Payot
Streptococcus suis is a leading cause of infection in pigs, causing extensive economic losses. In addition, it can also infect wild fauna, and can be responsible for severe infections in humans. Increasing antimicrobial resistance (AMR) has been described in S. suis worldwide and most of the AMR genes are carried by mobile genetic elements (MGEs). This contributes to their dissemination by horizontal gene transfer. A collection of 102 strains isolated from humans, pigs and wild boars in France was subjected to whole genome sequencing in order to: (i) study their genetic diversity, (ii) evaluate their content in virulence-associated genes, (iii) decipher the mechanisms responsible for their AMR and their association with MGEs, and (iv) study their ability to acquire extracellular DNA by natural transformation...
March 2024: Microbial Genomics
https://read.qxmd.com/read/38536202/venous-disorders-as-an-occupational-disease-a-systematic-review-on-epidemiology-pathophysiology-and-modification-strategies
#31
REVIEW
Tobias Hirsch, Uwe Wahl, Eberhard Rabe
<b/> Background: Forced postures are common in the workplace. Work in the primary economic sector is characterised by a high degree of physical activity and movement; however, activities in the secondary and tertiary sectors commonly require workers to stand or sit. An expansion of the tertiary sector in recent decades has meant that people in industrialised and emerging economies primarily sit or stand at work. The aim of the systematic review was to identify occupational factors relating to the presence of chronic venous disease (CVD), to place these in the context of developments in the workplace, and to determine whether measures are in place to prevent CVD...
March 27, 2024: VASA. Zeitschrift Für Gefässkrankheiten
https://read.qxmd.com/read/38536152/how-much-do-we-know-about-nursing-care-delivery-models-in-a-hospital-setting-a-mapping-review
#32
REVIEW
Klara Geltmeyer, Kristof Eeckloo, Laurence Dehennin, Emma De Meester, Sigrid De Meyer, Eva Pape, Margot Vanmeenen, Veerle Duprez, Simon Malfait
To deal with the upcoming challenges and complexity of the nursing profession, it is deemed important to reflect on our current organization of care. However, before starting to rethink the organization of nursing care, an overview of important elements concerning nursing care organization, more specifically nursing models, is necessary. The aim of this study was to conduct a mapping review, accompanied by an evidence map to map the existing literature, to map the field of knowledge on a meta-level and to identify current research gaps concerning nursing models in a hospital setting...
March 27, 2024: Nursing Inquiry
https://read.qxmd.com/read/38536140/primary-care-access-for-all-a-roadmap-for-addressing-the-primary-care-crisis-in-rhode-island
#33
JOURNAL ARTICLE
Jeffrey Borkan, Denise Coppa, Patricia Flanagan, Debra Hurwitz, Andrew Saal, Yolanda Bowes, Elena Nicolella, Peter Hollmann
BACKGROUND: Primary care in Rhode Island is in crisis. The dearth of primary care providers is already affecting access to services and the situation is likely to worsen unless major steps are taken. There are inadequate numbers of trainees in primary care medical residencies, nurse practitioner (NP) and physician assistant (PA) training programs who plan to practice primary care in our state. The Care Transformation Collaborative of RI (CTC-RI) has assembled a broadly representative task force of physicians, NPs, PAs, and others to build a strong and robust primary care delivery system across the state that recruits, trains, retains, and sustains primary care providers...
April 1, 2024: Rhode Island Medical Journal
https://read.qxmd.com/read/38536126/water-potential-from-adaptive-force-matching-for-ice-and-liquid-with-revised-dispersion-predicts-supercooled-liquid-anomalies-in-good-agreement-with-two-independent-experimental-fits
#34
JOURNAL ARTICLE
Raymond Weldon, Feng Wang
A revised version of the Water potential from Adaptive force matching for Ice and Liquid (WAIL) was developed by using the previous data set for fitting the WAIL model but with a dispersion term calculated using symmetry adapted perturbation theory (SAPT). The model has no adjustable parameters and relies solely on fitting first-principles information. The new model, named revised WAIL (rWAIL), shows improved predictions of most properties of water when compared to the previously published WAIL model. The rWAIL model also compares favorably to other first-principles-derived water models, such as MB-Pol, at only a fraction of the computational cost...
March 27, 2024: Journal of Physical Chemistry. B
https://read.qxmd.com/read/38536116/regular-use-of-aspirin-and-statins-reduces-the-risk-of-cancer-in-individuals-with-systemic-inflammatory-diseases
#35
JOURNAL ARTICLE
Jia-Run Lin, Duan-Duan Han, Wei Wei, Qin Zeng, Zi-Xuan Rong, Xue Bai, Yan-Pei Zhang, Jian Wang, Xiao-Ting Cai, Xu-Guang Rao, Si-Cong Ma, Zhong-Yi Dong
Aspirin has shown potential for cancer prevention, but a recent large randomized controlled trial found no evidence for a reduction in cancer risk. Given the anti-inflammatory effects of aspirin, systemic inflammatory diseases (SIDs), such as osteoporosis, cardiovascular diseases, and metabolic diseases, could potentially modify the aspirin-cancer link. To investigate the impact of aspirin in people with SIDs, we conducted an observational study on a prospective cohort of 478,615 UK Biobank participants. Individuals with at least one of the 41 SIDs displayed a higher cancer risk than those without SIDs...
March 27, 2024: Cancer Research
https://read.qxmd.com/read/38536101/evolution-of-intravenous-medication-errors-and-preventive-systemic-defenses-in-hospital-settings-a-narrative-review-of-recent-evidence
#36
JOURNAL ARTICLE
Sini Kuitunen, Marja Airaksinen, Anna-Riia Holmström
OBJECTIVES: Intravenous drug administration has been associated with severe medication errors in hospitals. The present narrative review is based on a systematic literature search, and aimed to describe the recent evolution in research on systemic causes and defenses in intravenous medication errors in hospitals. METHODS: This narrative review was based on Reason's theory of systems-based risk management. A systematic literature search covering the period from June 2016 to October 2021 was conducted on Medline (Ovid)...
March 28, 2024: Journal of Patient Safety
https://read.qxmd.com/read/38536070/conductive-peptide-based-mxene-hydrogel-as-a-piezoresistive-sensor
#37
JOURNAL ARTICLE
Dana Cohen-Gerassi, Or Messer, Gal Finkelstein-Zuta, Moran Aviv, Bar Favelukis, Yosi Shacham-Diamand, Maxim Sokol, Lihi Adler-Abramovich
Wearable pressure sensors have become increasingly popular for personal healthcare and motion detection applications due to recent advances in materials science and functional nanomaterials. In this study, we present a novel composite hydrogel as a sensitive piezoresistive sensor that can be utilized for various biomedical applications, such as wearable skin patches and integrated artificial skin that can measure pulse and blood pressure, as well as monitor sound as a self-powered microphone. The hydrogel is composed of self-assembled short peptides containing aromatic, positively- or negatively charged amino acids combined with 2D Ti3 C2 Tz MXene nanosheets...
March 27, 2024: Advanced Healthcare Materials
https://read.qxmd.com/read/38535979/understanding-multiple-sclerosis-as-a-disease-spectrum-above-and-below-the-clinical-threshold
#38
JOURNAL ARTICLE
Stephen Krieger, Karin Cook, Carrie M Hersh
PURPOSE OF REVIEW: Research in multiple sclerosis (MS) has long been predicated on clinical groupings that do not reflect the underlying biologic heterogeneity apparent within patient populations. This review explicates the various levels of explanation through which the spectrum of disease is described and investigated both above and below the clinical threshold of detection, as framed by the topographical model of MS, to help advance a cogent mechanistic framework. RECENT FINDINGS: Contemporary evidence has amended the view of MS as consisting of sequential disease phases in favor of a spectrum of disease with an admixture of interdependent and dynamic pathobiological axes driving tissue injury and progression...
March 28, 2024: Current Opinion in Neurology
https://read.qxmd.com/read/38535953/indications-of-endocrine-disruptor-effects-of-jp-5-jet-fuel-using-a-rat-model-reproductive-study-and-an-in-vitro-human-hormone-receptor-assay
#39
JOURNAL ARTICLE
William R Howard, Joyce G Rohan, Kimberly S B Yeager, Chester P Gut, Kathleen A Frondorf, Shawn M McInturf, Nathan M Gargas, Karen L Mumy
Recent events concerning jet fuel contamination of drinking water have shown that we need a better understanding of the effects of ingested jet fuel. To this end, a reproductive study with ingested jet fuel in rats was undertaken with relatively high concentrations of Jet Propellant (JP)-5 along with a human estrogen receptor activation in vitro assay using JP-5, JP-8, and an alternative jet fuel derived from the camelina plant referred to as HydroRenewable Jet (HRJ) fuel, to help evaluate potential effects of ingested jet fuel...
March 16, 2024: Toxics
https://read.qxmd.com/read/38535857/molecular-detection-of-candidatus-anaplasma-camelii-in-naturally-infected-dromedary-camels-camelus-dromedarius-in-abu-dhabi-emirate-united-arab-emirates-2019-2023
#40
JOURNAL ARTICLE
Hassan Zackaria Ali Ishag, Shameem Habeeba, El Tigani Ahmed El Tigani-Asil, Mohd Farouk Yuosf, Zulaikha Mohamed Abdel Hameed Al Hammadi, Abraham Nii Okai Commey, Hashel Talal Aboud Amer Bin Hraiz, Asma Abdi Mohamed Shah, Abdelmalik Ibrahim Khalafalla
The recent emergence of anaplasmosis in camels has raised global interest in the pathogenicity and zoonotic potential of the pathogen causing it and the role of camels as reservoir hosts. In the United Arab Emirates (UAE), molecular studies and genetic characterization of camel-associated Anaplasma species are limited. This study aimed to characterize molecularly Anaplasmataceae strains circulating in dromedary camels in the UAE. Two hundred eighty-seven whole-blood samples collected from dromedary camels across regions of the Abu Dhabi Emirate were received between 2019 and 2023 at the Abu Dhabi Agriculture and Food Safety Authority (ADAFSA) veterinary laboratories for routine diagnosis of anaplasmosis...
March 7, 2024: Veterinary Sciences
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