keyword
https://read.qxmd.com/read/38491857/psychiatric-risks-for-worsened-mental-health-after-psychedelic-use
#21
JOURNAL ARTICLE
Alessia Marrocu, Hannes Kettner, Brandon Weiss, Richard J Zeifman, David Erritzoe, Robin L Carhart-Harris
BACKGROUND: Resurgent psychedelic research has largely supported the safety and efficacy of psychedelic therapy for the treatment of various psychiatric disorders. As psychedelic use and therapy increase in prevalence, so does the importance of understanding associated risks. Cases of prolonged negative psychological responses to psychedelic therapy seem to be rare; however, studies are limited by biases and small sample sizes. The current analytical approach was motivated by the question of whether rare but significant adverse effects have been under-sampled in psychedelic research studies...
March 2024: Journal of Psychopharmacology
https://read.qxmd.com/read/38489017/leveraging-measurement-based-care-to-reduce-mental-health-treatment-disparities-for-populations-of-color
#22
JOURNAL ARTICLE
Jessica Barber, Amber W Childs, Sandra Resnick, Elizabeth H Connors
Disparities in mental health treatment have consistently been documented for clients of color as compared to White clients. Most mental health care disparities literature focuses on access to care at the point of initial engagement to treatment, resulting in a dearth of viable solutions being explored to retain clients in care once they begin. Measurement-based care (MBC) is a person-centered practice that has been shown to improve the therapeutic relationship, make treatment more personalized, and empower the client to have an active role in their care...
March 15, 2024: Administration and Policy in Mental Health
https://read.qxmd.com/read/38488093/mental-health-in-paediatric-and-adult-myositis-related-diseases-current-state-of-research-interventions-and-future-steps-from-the-mihra-psychological-impact-scientific-working-group
#23
REVIEW
Aviya Lanis, Helene Alexanderson, Kaveh Ardalan, Suzanne Edison, Christopher D Graham, Ingrid de Groot, Latika Gupta, Susan Kim, Andrea M Knight, Linda Kobert, Polly Livermore, Christian Lood, Clarissa Pilkington, Malin Regardt, Tamar B Rubinstein, Susan Shenoi, Luke Turnier, Nicole B M Voet, Dawn M Wahezi, Lesley Ann Saketkoo
Psychological and emotional well-being are critical aspects of overall health for individuals with chronic rheumatologic conditions. Mental health-related literature, however, predominantly focuses on systemic lupus erythematosus or rheumatoid arthritis, with limited emphasis on idiopathic inflammatory myopathies (IIMs). High proportions of those with juvenile myositis report psychological distress at levels warranting mental health referral. Adults with dermatomyositis diagnosed with depression or anxiety do not receive adequate mental health care...
February 2024: Clinical and Experimental Rheumatology
https://read.qxmd.com/read/38483940/the-therapeutic-alliance-between-study-participants-and-intervention-facilitators-is-associated-with-acute-effects-and-clinical-outcomes-in-a-psilocybin-assisted-therapy-trial-for-major-depressive-disorder
#24
JOURNAL ARTICLE
Adam W Levin, Rafaelle Lancelotta, Nathan D Sepeda, Natalie Gukasyan, Sandeep Nayak, Theodore L Wagener, Frederick S Barrett, Roland R Griffiths, Alan K Davis
We examined if the therapeutic alliance between study participants and intervention facilitators in a psilocybin-assisted therapy (PAT) trial changed over time and whether there were relationships between alliance, acute psilocybin experiences, and depression outcomes. In a randomized, waiting list-controlled clinical trial for major depressive disorder in adults (N = 24), participants were randomized to an immediate (N = 13) or delayed (N = 11) condition with two oral doses of psilocybin (20mg/70kg and 30mg/70kg)...
2024: PloS One
https://read.qxmd.com/read/38483789/does-the-mode-of-care-delivery-affect-therapeutic-alliance-patient-care-satisfaction-or-patient-reported-outcomes-psycho-oncological-care-evaluation-data-collected-during-the-covid-19-pandemic
#25
JOURNAL ARTICLE
Natalia Cecon-Stabel, Meriam Omairat, Sandra Salm, Anna Hagemeier, Antje Dresen, Theresia Krieger
PURPOSE: Since the COVID-19 pandemic, psycho-oncological care has increasingly been provided virtually and/or telephonically. We examined whether patients' therapeutic alliance (TA) - an essential processual outcome - differs due to altered modes of care delivery (MOCD) and assessed, if MOCD impacts patients' care satisfaction and patient reported outcomes. METHODS: Survey and documentation data from newly diagnosed cancer patients that were cared for in the new form of care 'isPO' in Germany, were analyzed...
March 14, 2024: Journal of Psychosocial Oncology
https://read.qxmd.com/read/38483750/the-effects-of-switching-to-video-therapy-on-in-session-processes-in-psychotherapy-during-the-covid-19-pandemic
#26
JOURNAL ARTICLE
Susanne Edelbluth, Brian Schwartz, Wolfgang Lutz
OBJECTIVE AND AIM: This study aimed to assess the impact of switching from face-to-face (f2f) psychotherapy to video therapy (VT) due to the COVID-19 pandemic on in-session processes, i.e., the therapeutic alliance, coping skills, and emotional involvement, as rated by both patients and therapists. METHODS: A total of N = 454 patients with mood or anxiety disorders were examined. The intervention group (IG) consisted of n = 227 patient-therapist dyads, who switched from f2f to VT, while the control group (CG) consisted of n = 227 patient-therapist dyads, who were treated f2f before the pandemic...
March 14, 2024: Administration and Policy in Mental Health
https://read.qxmd.com/read/38483053/the-relationship-between-expressive-suppression-therapeutic-bond-and-treatment-outcomes-of-a-positive-affect-intervention-for-adults-with-anxiety-and-or-depression
#27
JOURNAL ARTICLE
Samantha N Hoffman, Murray B Stein, Charles T Taylor
Expressive suppression (ES; reducing emotional expression) is linked with reduced social connectedness in individuals with anxiety or depression. One implication is that people who use ES may have difficulty establishing a bond with their therapist which may impede clinical improvement. We examined this hypothesis in 33 adults with clinically elevated anxiety or depression receiving treatment focused on enhancing positive thoughts, emotions, and behaviors. At baseline, participants rated ES for positive and negative emotions during a standardized conversation task designed to generate connectedness...
March 14, 2024: Cognitive Behaviour Therapy
https://read.qxmd.com/read/38482759/-challenges-and-perspectives-for-the-treatment-of-giant-cell-arteritis
#28
JOURNAL ARTICLE
Céline Schweri, Michele Iudici
Early diagnosis and prompt initiation of treatment are crucial to avoid severe complications in giant cell arteritis (GCA). The European Alliance of Associations for Rheumatology (EULAR) recommendations for the use of imaging in large vessel vasculitis have helped better define the role of different techniques for diagnosing and monitoring the disease. Regarding the treatment, corticosteroids remain the standard, and tocilizumab is the preferred corticosteroid-sparing treatment. New corticosteroid-sparing treatments and "ultra-light" corticosteroid usage regimens are also under study and could represent valid therapeutic alternatives in the future...
March 13, 2024: Revue Médicale Suisse
https://read.qxmd.com/read/38482732/borderline-personality-disorder-and-stigma-lived-experience-perspectives-on-helpful-and-hurtful-language
#29
JOURNAL ARTICLE
Charlotte C van Schie, Kate Lewis, Karlen R Barr, Mahlie Jewell, Natalie Malcolmson, Michelle L Townsend, Brin F S Grenyer
Borderline personality disorder (BPD) is a severe mental health disorder that is subject to significant stigmatisation. With language being a key reinforcer of stigma, this co-produced study aims to explore the language use regarding BPD and its effect on those with BPD and carers. Recommendations to reduce stigmatisation are provided for both clinicians and researchers. Participants with BPD (consumer n = 33) and those supporting someone with BPD (carer n = 30) discussed their experience of hurtful and helpful language...
March 14, 2024: Personality and Mental Health
https://read.qxmd.com/read/38481218/exploring-the-role-of-community-pharmacies-as-a-harm-reduction-environment-for-anabolic-androgenic-steroid-consumers-triangulating-the-perspectives-of-consumers-and-pharmacists
#30
JOURNAL ARTICLE
Timothy Piatkowski, Sarah Benn, Lkhagvadulam Ayurzana, Michelle King, Sara McMillan, Laetitia Hattingh
BACKGROUND: While community pharmacies have been successful in providing harm reduction support for illicit substance consumers, little research has explored their role in addressing the needs of anabolic-androgenic steroid (AAS) consumers. OBJECTIVE: This study aimed to triangulate the attitudes and experiences of AAS consumers and community pharmacist's regarding AAS harm reduction. METHODS: Semi-structured interviews were conducted with AAS consumers (n = 8) and community pharmacists (n = 15) between December 2022 and August 2023 in Australia...
March 13, 2024: Harm Reduction Journal
https://read.qxmd.com/read/38477975/navigating-social-cognitive-impairments-in-schizophrenia-spectrum-disorders-protocol-for-a-pilot-pre-post-quasi-experimental-study-for-remote-avatar-assisted-cognitive-remediation-therapy
#31
JOURNAL ARTICLE
Elisabeth Thibaudeau, Elodie Peyroux, Nicolas Franck, Hannah Carling, Martin Lepage
BACKGROUND: Social cognitive impairments are prevalent in schizophrenia spectrum disorder (SSD) and have detrimental effects on functioning. Cognitive remediation (CR) has shown its efficacy in improving social cognitive impairments, although the transfer of these skills to daily life and the personalization of these interventions remain challenging. RC2S (Remédiation Cognitive de la Cognition Sociale dans la Schizophrénie; Cognitive remediation of social cognition in Schizophrenia) is a French CR that combines the learning of strategies and practice using paper-and-pencil exercises and digital relational simulations...
March 13, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38477256/importance-of-capgras-syndrome-in-shared-psychotic-disorder-a-case-report
#32
JOURNAL ARTICLE
Vladimir Knezevic, Dragana Ratkovic, Svetlana Ivanovic Kovacevic, Valentina Sobot, Ana Marija Vejnovic, Masa Comic
Shared psychotic disorder characterized by Capgras syndrome is an extremely rare condition. To our knowledge, there are only a few published papers on this condition. This paper presents a case of shared Capgras syndrome in two sisters. The inducer was a younger sister with schizophrenia, who passed on her Capgras delusion to her older sister after the death of their father. After committing a violent offense caused by Capgras delusion, a court ordered the sisters' involuntary admission to a psychiatric hospital...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38467517/tolerability-and-safety-outcomes-of-first-line-oral-second-generation-antipsychotics-in-patients-with-schizophrenia
#33
REVIEW
Kristen Ward, Leslie Citrome
INTRODUCTION: Antipsychotics are the foundation of pharmacologic treatment for schizophrenia. There are many oral antipsychotics available and given that these medications are generally considered comparably efficacious when titrated to an adequate dose, their varied tolerability and safety profiles become critically important for medication selection. AREAS COVERED: This paper reviews tolerability and safety considerations for first-line second-generation oral antipsychotics currently approved for the treatment of schizophrenia in the United States...
March 11, 2024: Expert Opinion on Drug Safety
https://read.qxmd.com/read/38465669/exploring-mental-health-stigma-among-indonesian-healthcare-students-towards-individuals-with-mental-illnesses-a-qualitative-study
#34
JOURNAL ARTICLE
Muhammad Arsyad Subu, Jacqueline Maria Dias, Richard Mottershead, Fatma Refaat Ahmed, Sari Narulita, Maryuni Maryuni, Zakiyah Zakiyah, Irma Nurbaeti, Alounoud Mohamed Al Marzouqi, Nabeel Al-Yateem
BACKGROUND: The social disapproval or stigma surrounding mental illness contributes to the postponement of individuals seeking assistance and frequently undermines therapeutic alliances between mental illness sufferers and health care professionals. AIMS: This study explored perceptions and attitudes towards individuals with mental illness among college healthcare students in Indonesia. METHODS: This study used a qualitative method. Twenty five students enrolled in six healthcare programs were interviewed using a semi structured format...
December 2024: International Journal of Qualitative Studies on Health and Well-being
https://read.qxmd.com/read/38457374/identifying-central-elements-of-the-therapeutic-alliance-in-the-setting-of-telerehabilitation-a-qualitative-study
#35
JOURNAL ARTICLE
Barbara Seebacher, Carole Geimer, Julia Neu, Maria Schwarz, Gudrun Diermayr
INTRODUCTION: Therapeutic alliance is a relevant aspect of healthcare and may influence patient outcomes. So far, little is known about the therapeutic alliance in telerehabilitation. PURPOSE: To identify and describe central elements of therapeutic alliance in the setting of telerehabilitation and compare it to those in conventional rehabilitation. METHODS: In this qualitative study, a literature search and in-depth semi-structured interviews with rehabilitation and telerehabilitation experts were conducted from 15...
2024: PloS One
https://read.qxmd.com/read/38453365/oncogenic-mutations-of-kras-modulate-its-turnover-by-the-cul3-lztr1-e3-ligase-complex
#36
JOURNAL ARTICLE
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt M Kessler
KRAS is a proto-oncogene encoding a small GTPase. Mutations contribute to ∼30% of human solid tumours, including lung adenocarcinoma, pancreatic, and colorectal carcinomas. Most KRAS activating mutations interfere with GTP hydrolysis, essential for its role as a molecular switch, leading to alterations in their molecular environment and oncogenic signalling. However, the precise signalling cascades these mutations affect are poorly understood. Here, APEX2 proximity labelling was used to profile the molecular environment of WT, G12D, G13D, and Q61H-activating KRAS mutants under starvation and stimulation conditions...
May 2024: Life Science Alliance
https://read.qxmd.com/read/38451851/group-member-attachment-style-interacts-with-actor-and-partner-helping-alliance-to-predict-decreasing-binge-eating-episodes
#37
JOURNAL ARTICLE
Gianluca Lo Coco, Agostino Brugnera, Laura Salerno, Angelo Compare, Giorgio A Tasca, Dennis M Kivlighan
OBJECTIVE: An individual's attachment style may impact how they interact with their therapy group. This study examined the moderating role of a group member's attachment on the dynamic relationships between that group member's (actor) and other group members' (partner) therapeutic alliances and symptom outcomes. Method: This is a secondary analysis of data from a trial testing the outcome of emotionally-focused group therapy for binge-eating disorder. The sample consisted of 2,360 sessions nested within 118 group members who attended a 20-session treatment...
March 7, 2024: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://read.qxmd.com/read/38450504/impact-and-utility-of-follicular-lymphoma-gelf-criteria-in-routine-care-an-australasian-lymphoma-alliance-study
#38
JOURNAL ARTICLE
Allison Barraclough, Shivam Agrawal, Dipti Talaulikar, Geoffrey Chong, Edward Yoo, Chan Y Cheah, Nunzio Franco, Bianca Nguyen, Howard Mutsando, Fatima Tahir, Judith Trotman, Jing Huang, Colm Keane, Mitchel Lincoln, Tara Cochrane, Anna M Johnston, Michael Dickinson, Stephen Opat, Zoe K McQuilten, Erica M Wood, Gayathri St George, Eliza A Hawkes
Follicular Lymphoma (FL) treatment initiation is largely determined by tumor burden and symptoms. In the pre-rituximab era, the Group d'Etude des Lymphomes Folliculaires (GELF) developed widely adopted criteria to identify high tumor burden FL patients to harmonize clinical trial populations. The utilization of GELF criteria (GELFc) in routine therapeutic decision-making is poorly described. This multicenter retrospective study evaluated patterns of GELFc at presentation and GELFc utilization in therapeutic decision-making in newly diagnosed, advanced stage rituximab-era FL...
March 7, 2024: Haematologica
https://read.qxmd.com/read/38450288/an-integrated-action-plan-to-fund-and-support-drug-development-for-dup15q-syndrome-a-patient-organization-perspective
#39
JOURNAL ARTICLE
Ryan Rogers-Hammond, Carrie Howell
Maternal 15q11.2-13.1 duplication syndrome, or Dup15q syndrome (Dup15q), is a rare neurodevelopmental disorder affecting as many as 1 in 5000 to 1 in 20,000 children worldwide. Autism and seizures are two of the most commonly observed phenotypes in Dup15q, with intellectual disability, hypotonia, gastrointestinal distress, and substantial fine and gross motor deficits also commonly reported. The community that is now known as the Dup15q Alliance started in 1994 as a small group of families raising children with chromosome 15q duplications...
2024: Ther Adv Rare Dis
https://read.qxmd.com/read/38446599/a-psychometric-analysis-of-the-patterns-of-adapted-learning-scales-pals-with-a-group-psychotherapy-patient-sample-a-measure-of-motivation
#40
JOURNAL ARTICLE
Gerta Bardhoshi, Martin Kivlighan, Byeolbee Um
Previous research has examined the role of clients' goal orientation, or the motives one uses to achieve specific tasks or goals in individual therapy highlighting the importance of clients' goal orientation within a therapeutic context. Constructing and validating a measure of clients' achievement goal orientation in group psychotherapy is needed to allow for additional methodologically sound research to examine the role of achievement goal orientation in the process and outcome of group psychotherapy. Data from 99 adult group members across 23 interpersonal process groups were used to investigate the psychometric properties of the Patterns of Adapted Learning Scales-Group Psychotherapy Version (PALS-GP), including internal reliability, structural validity, and concurrent and criterion-related validity...
July 2023: International Journal of Group Psychotherapy
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