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https://www.readbyqxmd.com/read/28551569/investigation-of-interfacial-properties-of-pure-and-mixed-poloxamers-for-surfactant-mediated-shear-protection-of-mammalian-cells
#1
David Chang, Ryan Fox, Ethan Hicks, Rachel Ferguson, Kevin Chang, Douglas Osborne, Weiwei Hu, Orlin D Velev
The Poloxamer family of surfactants are commonly used in the biopharmaceutical industry as cell culture media additives to protect cells from the turbulent environment of sparged bioreactors. Despite the widespread use of poloxamers in cell culture, their performance as cell protectants varies depending on their physical structure, molecular weight, and batch-to-batch composition. In this study, the interfacial properties of Poloxamer 188 (P188), Poloxamer 407 (P407), and a mixture of P188 and P407 were characterized to investigate the mechanism of surfactant-mediated shear protection of mammalian cells...
May 16, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28551493/residential-greenness-and-adiposity-findings-from-the-uk-biobank
#2
Chinmoy Sarkar
BACKGROUND: With the rapid urbanization and prevailing obesity pandemic, the role of residential green exposures in obesity prevention has gained renewed focus. The study investigated the effects of residential green exposures on adiposity using a large and diverse population sample drawn from the UK Biobank. MATERIALS AND METHODS: This was a population based cross-sectional study of 333,183 participants aged 38-73years with individual-level data on residential greenness and built environment exposures...
May 25, 2017: Environment International
https://www.readbyqxmd.com/read/28548713/co-culture-systems-based-strategies-for-articular-cartilage-tissue-engineering
#3
REVIEW
Yu Zhang, Shuyun Liu, Weimin Guo, Mingjie Wang, Chunxiang Hao, Shuang Gao, Xueliang Zhang, Li Xu, Mingxue Chen, Li Penghao, Peng Jiang, Shibi Lu, Quanyi Guo
Cartilage engineering facilitates repair and regeneration of damaged cartilage using engineered tissue that restores the functional properties of the impaired joint. The seed cells used most frequently in tissue engineering, are chondrocytes and mesenchymal stem cells. Seed cells activity plays a key role in the regeneration of functional cartilage tissue. However, seed cells undergo undesirable changes after in vitro processing procedures, such as degeneration of cartilage cells and induced hypertrophy of mesenchymal stem cells, which hinder cartilage tissue engineering...
May 26, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28548556/a-physical-education-intervention-effects-on-correlates-of-physical-activity-and-motivation
#4
Stephen E Palmer, Dierdra K Bycura, Meghan Warren
PURPOSE: The purpose of this study was to measure effects of a modified physical education (PE) unit on leisure time physical activity (LTPA), relative autonomy, and known correlates of LTPA in seventh-grade boys and girls. METHOD: A seventh-grade mountain biking unit was modified to include instructional activities targeting known correlates of PA behavior following principles of Physical Education Dedicated to Physical Activity for Life (PEDAL). A three-group design (intervention, standard PE, no PE) was employed...
May 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28546137/activity-recognition-for-persons-with-stroke-using-mobile-phone-technology-toward-improved-performance-in-a-home-setting
#5
Megan K O'Brien, Nicholas Shawen, Chaithanya K Mummidisetty, Saninder Kaur, Xiao Bo, Christian Poellabauer, Konrad Kording, Arun Jayaraman
BACKGROUND: Smartphones contain sensors that measure movement-related data, making them promising tools for monitoring physical activity after a stroke. Activity recognition (AR) systems are typically trained on movement data from healthy individuals collected in a laboratory setting. However, movement patterns change after a stroke (eg, gait impairment), and activities may be performed differently at home than in a lab. Thus, it is important to validate AR for gait-impaired stroke patients in a home setting for accurate clinical predictions...
May 25, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28545539/the-role-of-nature-in-cancer-patients-lives-a-systematic-review-and-qualitative-meta-synthesis
#6
Sarah Blaschke
BACKGROUND: A systematic review and meta-synthesis was conducted to identify, compare and synthesize the published qualitative literature contributing to our understanding of the role of nature in cancer patients' lives. METHOD: An electronic search of Medline, CINAHL, PsycINFO and Cochrane Databases was conducted to identify qualitative studies focused on cancer patients' nature experiences published between January 1985 and May 2015. Records were assessed according to pre-defined inclusion criteria...
May 25, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28545415/capturing-how-age-friendly-communities-foster-positive-health-social-participation-and-health-equity-a-study-protocol-of-key-components-and-processes-that-promote-population-health-in-aging-canadians
#7
Mélanie Levasseur, Marie-France Dubois, Mélissa Généreux, Verena Menec, Parminder Raina, Mathieu Roy, Catherine Gabaude, Yves Couturier, Catherine St-Pierre
BACKGROUND: To address the challenges of the global aging population, the World Health Organization promoted age-friendly communities as a way to foster the development of active aging community initiatives. Accordingly, key components (i.e., policies, services and structures related to the communities' physical and social environments) should be designed to be age-friendly and help all aging adults to live safely, enjoy good health and stay involved in their communities. Although age-friendly communities are believed to be a promising way to help aging Canadians lead healthy and active lives, little is known about which key components best foster positive health, social participation and health equity, and their underlying mechanisms...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28544991/associations-of-neighborhood-social-environment-attributes-and-physical-activity-among-9-11-year-old-children-from-12-countries
#8
Samaah M Sullivan, Stephanie T Broyles, Tiago V Barreira, Jean-Philippe Chaput, Mikael Fogelholm, Gang Hu, Rebecca Kuriyan, Anura Kurpad, Estelle V Lambert, Carol Maher, Jose Maia, Victor Matsudo, Tim Olds, Vincent Onywera, Olga L Sarmiento, Martyn Standage, Mark S Tremblay, Catrine Tudor-Locke, Pei Zhao, Peter T Katzmarzyk
We investigated whether associations of neighborhood social environment attributes and physical activity differed among 12 countries and levels of economic development using World Bank classification (low/lower-middle-, upper-middle- and high- income countries) among 9-11 year old children (N=6161) from the International Study of Childhood Obesity, Lifestyle, and the Environment (ISCOLE). Collective efficacy and perceived crime were obtained via parental/guardian report. Moderate-to-vigorous physical activity (MVPA) was assessed with waist-worn Actigraph accelerometers...
May 22, 2017: Health & Place
https://www.readbyqxmd.com/read/28543739/sound-at-the-zoo-using-animal-monitoring-sound-measurement-and-noise-reduction-in-zoo-animal-management
#9
David A Orban, Joseph Soltis, Lori Perkins, Jill D Mellen
A clear need for evidence-based animal management in zoos and aquariums has been expressed by industry leaders. Here, we show how individual animal welfare monitoring can be combined with measurement of environmental conditions to inform science-based animal management decisions. Over the last several years, Disney's Animal Kingdom® has been undergoing significant construction and exhibit renovation, warranting institution-wide animal welfare monitoring. Animal care and science staff developed a model that tracked animal keepers' daily assessments of an animal's physical health, behavior, and responses to husbandry activity; these data were matched to different external stimuli and environmental conditions, including sound levels...
May 23, 2017: Zoo Biology
https://www.readbyqxmd.com/read/28543269/building-expert-agreement-on-the-importance-and-feasibility-of-workplace-health-promotion-interventions-for-nurses-and-midwives-a-modified-delphi-consultation
#10
Lin Perry, Rachel Nicholls, Christine Duffield, Robyn Gallagher
AIM: To use a Delphi panel to determine the relative importance and feasibility of workplace health promotion interventions to promote and support the health of the Australian nursing and midwifery workforce BACKGROUND: The nursing workforce experiences rates of ill health above that of other workforces yet there is little investment in workplace health promotion. DESIGN: The study used a modified Delphi design conducted between September - November 2015. METHODS: Eleven of 19 purposively selected expert panellists discussed, rated and provided feedback through two rounds of an electronic questionnaire about the relative importance and feasibility of 46 workplace health promotion interventions and processes for nurses and midwives...
May 24, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28542908/an-appraisal-of-the-enzyme-stability-activity-trade-off
#11
Scott R Miller
A longstanding idea in evolutionary physiology is that an enzyme cannot jointly optimize performance at both high and low temperatures due to a trade-off between stability and activity. Although a stability-activity trade-off has been observed for well-characterized examples, such a trade-off is not imposed by any physical chemical constraint. To better understand the pervasiveness of this trade-off, I investigated the stability-activity relationship for comparative biochemical studies of purified orthologous enzymes identified by a literature search...
May 24, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28542529/associations-between-quality-of-life-physical-activity-worry-depression-and-insomnia-a-cross-sectional-designed-study-in-healthy-pregnant-women
#12
Danielle Mourady, Sami Richa, Rita Karam, Tatiana Papazian, Fabienne Hajj Moussa, Nada El Osta, Assaad Kesrouani, Joseph Azouri, Hicham Jabbour, Aline Hajj, Lydia Rabbaa Khabbaz
Health-related quality of life (QOL) is reported to be reduced during pregnancy. Associations between QOL, physical activity (PA), insomnia, depression and worry are insufficiently investigated among pregnant women. The aim of this study was to evaluate QOL and PA patterns among healthy pregnant women, and to examine how QOL might correlate to PA, sleep, worry and depression. This is an observational cross-sectional study, conducted among a convenient sample of 141 healthy pregnant women using five questionnaires: WHOQOL-brief (WHO quality of life questionnaire, brief version, ISI (Insomnia Severity Index), PSWQ (Penn State Worry Questionnaire), ZSRDS (Zung Self-Rating Depression Scale), and Pregnancy Physical Activity Questionnaire (PPAQ)...
2017: PloS One
https://www.readbyqxmd.com/read/28539486/how-and-why-do-toxic-conformers-of-aberrant-proteins-accumulate-during-ageing
#13
REVIEW
Rebecca Josefson, Rebecca Andersson, Thomas Nyström
Ageing can be defined as a gradual decline in cellular and physical functions accompanied by an increased sensitivity to the environment and risk of death. The increased risk of mortality is causally connected to a gradual, intracellular accumulation of so-called ageing factors, of which damaged and aggregated proteins are believed to be one. Such aggregated proteins also contribute to several age-related neurodegenerative disorders e.g. Alzheimer's, Parkinson's, and Huntington's diseases, highlighting the importance of protein quality control (PQC) in ageing and its associated diseases...
May 24, 2017: Essays in Biochemistry
https://www.readbyqxmd.com/read/28539425/perceptual-competition-promotes-suppression-of-reward-salience-in-behavioral-selection-and-neural-representation
#14
Mengyuan Gong, Ke Jia, Sheng Li
Visual attentional selection is influenced by the value of objects. Previous studies have demonstrated that reward-associated items lead to rapid distraction and associated behavioral costs, which are difficult to override with top-down control. However, it has not been determined whether a perceptually competitive environment could render the reward-driven distraction more susceptible to top-down suppression. Here, we trained both genders of human subjects to associate two orientations with high and low magnitudes of reward...
May 24, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28538669/the-peroxisome-mitochondria-connection-how-and-why
#15
REVIEW
Marc Fransen, Celien Lismont, Paul Walton
Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid and reactive oxygen species metabolism. In mammals, these organelles have also been recognized as important hubs in redox-, lipid-, inflammatory-, and innate immune-signaling networks. To exert these activities, peroxisomes must interact both functionally and physically with other cell organelles. This review provides a comprehensive look of what is currently known about the interconnectivity between peroxisomes and mitochondria within mammalian cells...
May 24, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28537204/best-practice-in-the-management-of-clinical-coding-services
#16
Beth A Reid, Lee Ridoutt, Paul O'Connor, Deirdre Murphy
INTRODUCTION: This is the second of two articles about best practice in the management of coding services. The best practice project was part of a year-long project conducted in the Republic of Ireland to review the quality of the Hospital Inpatient Enquiry data for its use in activity-based funding. METHODS: The four methods used to address the best practice aspect of the project were described in detail in Part 1. RESULTS: The results included in this article are those relating to the coding manager's background, preparation and style, clinical coder (CC) workforce adequacy, the CC workforce structure and career pathway, and the physical and psychological work environment for the clinical coding service...
January 1, 2017: HIM Journal
https://www.readbyqxmd.com/read/28536945/back-and-neck-pain-prevalence-and-their-association-with-physical-inactivity-domains-in-adolescents
#17
Catarina Covolo Scarabottolo, R Z Pinto, C B Oliveira, E F Zanuto, J R Cardoso, D G D Christofaro
PURPOSE: Back pain affects people of all ages. This may be associated with physical inactivity, and in the case of physical activity in different domains, the relationship with back pain is not clear in the literature. The aim of this study was to estimate the prevalence of low back and neck pain and investigate their association in different domains of physical inactivity. METHODS: 1011 randomly selected students participated in this study. Neck and back pain were assessed using the Nordic questionnaire, whereas the Baecke Physical Activity questionnaire was used to measure physical activity domains...
May 23, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28536499/decreasing-sedentary-behavior-effects-on-academic-performance-meta-cognition-and-sleep
#18
June J Pilcher, Drew M Morris, Stewart A Bryant, Paul A Merritt, Hayley B Feigl
There is growing interest in using activity workstations as a method of increasing light physical activity in normally sedentary environments. The current study (N = 117) compared the effects of studying in college students while slowly pedaling a stationary bike with a desktop with studying at traditional desks across 10 weeks in an academic semester. The students were assigned to study either on the stationary bike or at a traditional desk located in the campus library for a minimum of 2 h a week. During the 10 weeks, the students studied for tests or worked on other required academic activities while working at their assigned desk...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28536269/a-cognition-related-neural-oscillation-pattern-generated-in-the-prelimbic-cortex-can-control-operant-learning-in-rats
#19
Samuel Hernández-González, Celia Andreu-Sánchez, Miguel Ángel Martín-Pascual, Agnès Gruart, José María Delgado-García
The prelimbic (PrL) cortex constitutes one of the highest levels of cortical hierarchy dedicated to the execution of adaptive behaviors. We have identified a specific local field potential (LFP) pattern generated in the PrL cortex, associated with cognition-related behaviors, and used it to trigger the activation of a visual display on a touch screen as part of an operant conditioning task. Rats learned to increase the presentation rate of the selected theta/beta-gamma transition pattern across training sessions...
May 23, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28535815/internet-based-attentional-bias-modification-training-as-add-on-to-regular-treatment-in-alcohol-and-cannabis-dependent-outpatients-a-study-protocol-of-a-randomized-control-trial
#20
Janika Heitmann, Madelon E van Hemel-Ruiter, Karin M Vermeulen, Brian D Ostafin, Colin MacLeod, Reinout W Wiers, Laura DeFuentes-Merillas, Martine Fledderus, Wiebren Markus, Peter J de Jong
BACKGROUND: The automatic tendency to attend to and focus on substance-related cues in the environment (attentional bias), has been found to contribute to the persistence of addiction. Attentional bias modification (ABM) interventions might, therefore, contribute to treatment outcome and the reduction of relapse rates. Based on some promising research findings, we designed a study to test the clinical relevance of ABM as an add-on component of regular intervention for alcohol and cannabis patients...
May 23, 2017: BMC Psychiatry
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