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Surgicel Nu-knit

Kreg Howk, Jason Fortier, Robert Poston
BACKGROUND: Achieving hemostasis during surgery is a common challenge across surgical specialties and procedures, including cardiovascular and peripheral vascular procedures. Although several hemostatic agents are available, they all become less effective as bleeding becomes more vigorous. Veriset™ hemostatic patch is a topical hemostatic agent that has been approved for use on solid organs and in soft tissue. The primary aim of these studies was to assess the safety of Veriset hemostatic patch during cardiovascular and peripheral vascular procedures...
February 2016: Annals of Vascular Surgery
Scott M Tackett, Rebecca Sugarman, Huub T C Kreuwel, Piedad Alvarez, Giuseppe Nasso
OBJECTIVE: Improved health outcomes can result in economic savings for hospitals and payers. While effectiveness of topical hemostatic agents in cardiac surgery has been demonstrated, evaluations of their economic benefit are limited. This study quantifies the cost consequences to hospitals, based on clinical outcomes, from using a flowable hemostatic matrix vs non-flowable topical hemostatic agents in cardiac surgery. RESEARCH DESIGN AND METHODS: Applying clinical outcomes from a prospective randomized clinical trial, a cost consequence framework was utilized to model the economic impact of comparator groups...
September 2014: Journal of Medical Economics
Rena Moon, Andre Teixeira, Sheila Varnadore, Kelly Potenza, Muhammad A Jawad
BACKGROUND: In the literature, staple line leak rate is reported to be 1-6 %, and hemorrhage rate is 2-5 % in laparoscopic Roux-en-Y gastric bypass (LRYGB). Various buttress materials are available in an attempt to reduce perioperative complications. The aims of our study are to evaluate the effect of using absorbable hemostat (SNK) as buttress material and compare its usage with bovine pericardial strips (PSD). METHODS: Between January 2006 to May 2007 and from October 2007 to December 2009, a total of 1,074 patients underwent LRYGB at our institution...
June 2013: Obesity Surgery
Thomas Syburra, Dominik Weishaupt, Kirk Graves, Michele Genoni
Oxidized regenerated cellulose is widely used as a bioabsorbable topical hemostatic agent. Postoperative visualization of this material through routine chest imaging, such as conventional radiography, computer tomography (CT), magnetic resonance imaging as well as sonography, may prove difficult and, to our knowledge, is not described in the literature. We describe a case where the mediastinal packing with Surgicel™ Nu-Knit™ after a mitral valve repair procedure led to a delayed obstruction of the superior vena cava, necessitating a re-thoracotomy and curettage of the hemostatic material...
April 2011: Interactive Cardiovascular and Thoracic Surgery
Richard W Hutchinson, Duan Broughton, Thomas A Barbolt, Thomas Poandl, Tim Muench, Rick Rockar, Mark Johnson, James Hart
BACKGROUND: Current management of severe surgical or traumatic bleeding is often achieved by manual tamponade or occlusion using devices such as tourniquets or ligatures. There are some clinical scenarios where these options are either marginally effective or impractical. The present study evaluates a new combination device (Fibrin pad) consisting of biologically active components (human thrombin and fibrinogen) delivered to the targeted site by an absorbable synthetic matrix (oxidized regenerated cellulose and polyglactin 910) in a swine severe bleeding model...
May 15, 2011: Journal of Surgical Research
Iu V Belov, V V Bazylev, I A Alekseev
Efficacy of the oxygenated regenerated cellulose Surgicel Nu-Knit as a hemostatic agent by coronary shunting operation was evaluated. 84 patients were included in the study. Surgicel was locally used in 32 of patients after sternotomy and during wound closure. Intraoperative blood loss in the group of interest was higher than in the control group: 1215,4+/-146,3 ml (14,9+/-3,1 ml/kg) vs. 1066,6+/-106,8 ml (11,5+/-3,3 ml/kg). Surgicel Nu-Knit for the sternum bleeding permitted a good hemostatic effect without wax use...
2009: Khirurgiia
J B Sharma, Monika Malhotra
INTRODUCTION: Uterine hemorrhage is a common problem at the time of caesarean section especially in a repeat caesarean section and when the operation is performed for placenta praevia. CASE REPORT AND DISCUSSION: We present the case of a 28 year old woman undergoing a repeat emergency caesarean section for scar tenderness. She had excessive hemorrhage from the incision site that could not be controlled by traditional management including intravenous oxytocin and ergometrine, intramyometrial prostaglandin and local hemostatic sutures, but was successfully controlled with topical oxidized regenerated cellulose absorbable hemostat...
May 2006: Archives of Gynecology and Obstetrics
Helmut Mair, Ingo Kaczmarek, Martin Oberhoffer, Jan Groetzner, Sabine Daebritz, Bruno Reichart
No abstract text is available yet for this article.
August 2005: Journal of Thoracic and Cardiovascular Surgery
Daniel Spangler, Stephen Rothenburger, Kien Nguyen, Hanuman Jampani, Scott Weiss, Shubhangi Bhende
BACKGROUND: The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose (ORC), is a broad-spectrum physiological detriment to survival of microorganisms known to cause surgical infections. The purpose of this study was to examine the antimicrobial effect of ORC against antibiotic-resistant organisms. METHODS: ORC products were challenged with ATCC reference strains and clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), vancomycin-resistant Enterococcus (VRE), penicillin-resistant Streptococcus pneumoniae (PRSP), and non-resistant ATCC strains of S...
2003: Surgical Infections
C A Shinkwin, N Beasley, R Simo, L Rushton, N S Jones
A randomised, prospective trial to evaluate Surgicel Nu-knit with Vasolene ribbon gauze and Merocel packs, respectively. Sixty patients (36 males and 24 females) undergoing bilateral nasal surgery, each having the same procedure performed on both sides, were recruited. The mean age was 49 years (range: 16-70 years). At operation, Surgicel Nu-knit was placed in one nostril, the other nostril was randomised to Vasolene gauze or Merocel. Twenty-four hours post-operatively, patients were asked to assess the discomfort experienced in either side of the nose while the packs were in position and on removal...
March 1996: Rhinology
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