keyword
https://read.qxmd.com/read/38529664/strategies-for-co-2-laser-use-in-laryngeal-microsurgery-a-systematic-review
#1
REVIEW
Vivianne Landry, Ève Sedillot-Daniel, Tareck Ayad, Andrée-Anne Leclerc
OBJECTIVE: We aim to systematically review the literature addressing perioperative practices for optimal use of the CO2 laser in laryngeal transoral laser microsurgery (TOLMS), with a focus on safety. DATA SOURCES: A systematic review of publications indexed in Medline, Embase, and EBM reviews-Cochrane Central Register of Controlled Trials which evaluated perioperative strategies for the use of CO2 laser in laryngeal TOLMS was conducted. REVIEW METHODS: Records obtained from the search strategy were assessed for eligibility in a 2-step process by 2 independent researchers using the Covidence software...
March 26, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38500712/a-case-of-photoimmunotherapy-for-nasopharyngeal-carcinoma-requiring-emergency-tracheostomy
#2
Yukiomi Kushihashi, Tatsuo Masubuchi, Isaku Okamoto, Chihiro Fushimi, Morio Yamazaki, Hisashi Asano, Reo Aoki, Shota Fujii, Yukiko Asako, Yuichiro Tada
INTRODUCTION: Photoimmunotherapy (PIT) is a treatment wherein intravenous cetuximab sarotalocan sodium is administered followed by laser light irradiation. This treatment exhibits a specific antitumor effect if in tumors expressing the epidermal growth factor receptor, regardless of the carcinoma [Mitsunaga et al.: Nat Med. 2011;17(12):1685-91, Sato et al.: ACS Cent Sci. 2018;4(11):1559-69, Nakajima et al.: Cancer Sci. 2018;109(9):2889-96]. The current indications are unresectable, locally advanced, or locally recurrent head and neck cancer...
2024: Case Reports in Oncology
https://read.qxmd.com/read/38435927/understanding-zenker-s-diverticulum-treatment-transoral-co2-laser-microsurgery
#3
Patrícia S Sousa, Helena Silveira, Gil Coutinho, Cecília Pereira, Carla P Moura
The authors present a case of a 36-year-old woman with a recurrent throat foreign body sensation and persistent dysphagia. On physical examination, a polypoid mass was visible at the postcricoid region, mobile with swallowing. A barium swallowing test confirmed the diagnosis of Zenker's diverticulum. The patient underwent transoral CO2 laser microsurgery for excision of the pharyngeal pouch. At the four-month evaluation, the patient was remarkably asymptomatic and without evidence of recurrence. This clinical case illustrates in detail the endoscopic view of the pre and postoperative aspects of the pharyngeal pouch, showing a step-by-step transoral CO2 laser microsurgery technique, with video...
January 2024: Curēus
https://read.qxmd.com/read/38424299/transoral-laser-microsurgery-for-t1-glottic-cancer-with-anterior-commissure-identifying-clinical-and-radiological-variables-that-predict-oncological-outcome
#4
JOURNAL ARTICLE
Caglar Eker, Ozgur Surmelioglu, Muhammed Dagkiran, Omer Kaya, Ilda Tanrisever, Burak Arpaci, Bedir Kaya, Sevinc Puren Yucel Karakaya, Elvan Onan
PURPOSE: The involvement of the anterior commissure (AC) is regarded to be a risk factor for poor results after transoral laser microsurgery (TLM) for early glottic cancer. The objective of this study was to determine how AC-related clinical and radiological factors affected oncological outcomes in a cohort of patients with T1 stage early glottic carcinoma involving the anterior commissure who were treated with TLM with negative surgical margins. METHODS: Retrospective analysis was performed on clinical, radiological, and follow-up data of patients consecutively treated with TLM at a tertiary academic center between November 2011 and August 2021 for T1 glottic squamous cell carcinoma involving the anterior commissure...
February 29, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38420351/racial-disparities-in-surgical-management-for-early-stage-laryngeal-squamous-cell-carcinoma-and-recurrent-dysplasia
#5
JOURNAL ARTICLE
Thomas F Cyberski, Alexander Z Wang, Brandon J Baird
OBJECTIVE: The aim of this study is to evaluate the association between race and the treatment of laryngeal dysplasia and early-stage laryngeal squamous cell carcinoma (LSCC). STUDY DESIGN: Retrospective Cohort Study. SETTING: Large multispecialty academic medical center. METHODS: Patients were treated for laryngeal dysplasia or LSCC between September 2019 and September 2022. A retrospective chart review was conducted to collect demographic and clinical information...
2024: OTO Open
https://read.qxmd.com/read/38414192/airway-protection-and-outcomes-after-staged-versus-concurrent-bilateral-neck-dissections-with-transoral-base-of-tongue-cancer-resection
#6
JOURNAL ARTICLE
Jake J Lee, Nicholas A Rapoport, Patrik Pipkorn, Sidharth V Puram, Ryan S Jackson
OBJECTIVES: To assess airway, safety, and resource utilization outcomes between transoral base of tongue (BOT) surgery with staged versus concurrent bilateral neck dissections (BND). METHODS: A retrospective cohort study of patients with human papilloma virus (HPV)-related BOT cancer who underwent transoral surgery and BND from January 2015 through June 2022 was conducted. Free flap patients were excluded. RESULTS: Of 126 patients (46 [37%] staged and 80 [63%] concurrent BND), there were no significant differences in rates of postoperative intubation, tracheostomy, intensive care admission, operative takebacks, gastrostomy, and 30-day readmission...
February 27, 2024: Head & Neck
https://read.qxmd.com/read/38386208/awake-endoscopic-laser-surgery-for-early-glottic-carcinoma
#7
JOURNAL ARTICLE
Petru Gurău
The objective of this study was to demonstrate the oncologic efficacy of awake endoscopic laryngeal surgery in the treatment of T1-T2 glottic carcinoma. This is a retrospective study. Seventy-one patients with early glottic carcinoma (T1a- 26, T1b- 18, T2- 27) who underwent awake flexible endoscopic laryngeal surgery under local anesthesia and mild intravenous sedation were included in the study. In 64 cases (90.1%) only endoscopic tumor ablation by Nd:YAG laser (in 32.4% of cases being preceded by diathermy snare excision) was performed, and in 7 T2 cases postoperative radiotherapy was also offered...
February 22, 2024: Lasers in Medical Science
https://read.qxmd.com/read/38196290/prognostic-value-of-preoperative-inflammatory-ratios-in-early-glottic-cancer-treated-with-transoral-laser-surgery
#8
JOURNAL ARTICLE
Luis Juesas Iglesias, Mario Sánchez-Canteli, Daniel Pedregal Mallo, María Otero-Rosales, Fernando López, Juana M García-Pedrero, Juan P Rodrigo
BACKGROUND: There is growing evidence regarding the prognostic utility of ratios such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammatory index (SIII) in head and neck squamous cell carcinoma (HNSCC). However, most studies to date include heterogeneous series with different treatments or tumor subsites. METHODS: We collected data from 201 patients with stage I-II glottic squamous cell carcinoma treated with transoral laser surgery...
January 9, 2024: Head & Neck
https://read.qxmd.com/read/38158419/recent-updates-in-laryngeal-hemangioma-management-a-scoping-review
#9
REVIEW
Ali Almothahbi, Manal Bukhari, Mohammed Almohizea, Nawaf Alsubaie, Talal F Alharbi, Hassan M Alhazzani, Faisal Zagzoog
PURPOSE: To provide a comprehensive review of the current strategies in the management of laryngeal hemangiomas, with an aim to introduce a management algorithm that aligns with the variable clinical presentations and anatomical complexities of these lesions. METHODS: We conducted an extensive literature search across major databases using specific and general terms, combined with Boolean operators, to ensure comprehensiveness. Articles from January 2004 to August 2023 were included, with findings categorized by management approach...
December 29, 2023: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38130264/management-of-positive-resection-margins-following-transoral-laser-microsurgery-for-glottic-cancer
#10
JOURNAL ARTICLE
Usman Khan, Colin MacKay, Matthew Rigby, Jonathan Trites, Martin Corsten, S Mark Taylor
OBJECTIVES: The current literature provides limited guidance on the management of positive margins (PMs) following transoral laser microsurgery (TLM) for glottic squamous cell carcinoma (SCC). Long-term data exploring the treatment of PMs with both initial observation and re-resection are limited. Our objective was to determine the optimal treatment for PM patients following TLM for glottic SCC. METHODS: Clinical information on glottic SCC patients with PMs following treatment with TLM was prospectively collected at our institution from 2007 to 2018...
December 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/38092608/removal-of-intraglandular-calculi-in-wharton-s-duct-clinical-outcome-and-treatment-algorithm
#11
JOURNAL ARTICLE
Y-N Zhao, D-N Zheng, L-Y Qu, X-Y Xie, D-G Liu, G-Y Yu
The aim of this study was to propose a treatment strategy for intraglandular submandibular calculi based on calculus site. Seventy-three consecutive patients with impalpable intraglandular submandibular calculi were enrolled retrospectively. The calculi were classified as either post-hilar type, central type, or superficial type. Treatment approaches included transoral duct slitting (TDS), interventional basket retrieval (IBR), intraductal laser lithotripsy (ILL), and transcervical lithotomy (TCL). Complete calculus removal with gland preservation was achieved in 64 patients (87...
December 12, 2023: International Journal of Oral and Maxillofacial Surgery
https://read.qxmd.com/read/37956498/outcomes-of-mini-invasive-transoral-surgery-without-neck-dissection-in-supraglottic-laryngeal-cancer-real-world-data-from-a-tertiary-cancer-center
#12
JOURNAL ARTICLE
Stefano Zorzi, Giacomo Pietrobon, Chiara Mossinelli, Francesco Bandi, Francesco Chu, Marta Tagliabue, Rita De Berardinis, Jacopo Zocchi, Daniela Alterio, Maria Cossu Rocca, Francesca Ruju, Mohssen Ansarin
PURPOSE: The neck management in early-stage cN0 supraglottic cancer represents an argument of debate. The aim of our study is to evaluate the oncological and functional outcomes in patients with early-stage cN0 supraglottic carcinoma treated with a wait-and-see policy for the neck. MATERIALS AND METHODS: Retrospective monocentric cohort study in a referral cancer care center. We collected a consecutive sample of patients from 2000 to 2020 with Squamous Cell Carcinoma of the supraglottis without clinical evidence of nodal metastases (cN0), surgically treated with Transoral Surgery (Laser or Robotic) without neck dissection...
November 10, 2023: American Journal of Otolaryngology
https://read.qxmd.com/read/37948822/oncological-outcomes-and-failure-patterns-of-laser-cordectomy-in-recurrent-glottic-cancer
#13
JOURNAL ARTICLE
Roee Noy, Yotam Shkedy, Nadeem Habashi, Salem Billan, Jacob Cohen
PURPOSE: Laser cordectomy is a widely accepted treatment modality for selected cases of early glottic cancers, but its role as a salvage treatment remains unclear. We aimed to investigate the oncological outcomes and failure patterns of salvage cordectomy. MATERIALS AND METHODS: This was a retrospective cohort study of patients who underwent cordectomy for early glottic cancer between 2013 and 2022 at a tertiary referral center. The main outcome measures were overall survival, larynx-preservation rate, tracheostomy dependency rate, and disease-free survival...
November 3, 2023: American Journal of Otolaryngology
https://read.qxmd.com/read/37860983/panitumumab-irdye800-improves-laryngeal-tumor-mapping-during-transoral-laser-microsurgery
#14
Luke Bailey, Logan D Stone, Manuel L Gonzalez, Carissa M Thomas, Hari Jeyarajan, Jason M Warram, Bharat Panuganti
Transoral laser microsurgery represents the primary surgical modality for early laryngeal cancers with oncologic outcomes equivalent to radiotherapy. Accurate tumor mapping and margin assessment can be difficult, however, particularly during piecemeal or ablative resections, and for tumors with a wider geographic footprint. Tumor-targeted fluorescence-guided surgery in patients with head and neck cancer has empirically improved tumor and margin identification; this case details, for the first time, a fluorescence-guided surgical resection of a T2N0M0 transglottic tumor using panitumumab-IRDye800, an epidermal growth factor receptor monoclonal antibody covalently linked to near-infrared (NIR) dye...
October 20, 2023: Laryngoscope
https://read.qxmd.com/read/37847285/permanent-occlusion-of-the-eustachian-tube-a-retrospective-study-on-reopening-procedures
#15
JOURNAL ARTICLE
Holger Sudhoff
PURPOSE: This study retrospectively evaluated the efficacy and versatility of reopening procedures for the permanent occlusion of the cartilaginous Eustachian tube (POET) by analyzing four consecutive cases. METHODS: The study included all patients diagnosed with POET who suffered from Eustachian tube occlusion and glue ear. A combined approach of endoscopic transnasal/transoral laser surgery was utilized to reopen the POET. This was subsequently followed by balloon dilation (BET) and stenting for a duration of six weeks...
October 17, 2023: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/37837405/horizontal-middle-partial-laryngectomy-with-cricothyroidopexy-an-effective-treatment-for-stage-t1b-glottic-carcinoma
#16
JOURNAL ARTICLE
Shiyan Chen, Hongxun Gong, Ning Huang, Fan Yang, Maoxin Wang
BACKGROUND: The current treatment options for T1b glottic carcinoma often lead to poor treatment outcomes or voice quality. OBJECTIVES: This study evaluates the therapeutic efficacy of horizontal middle partial laryngectomy with cricothyroidopexy (HMPL-CTP) for stage T1b glottic carcinoma. MATERIAL AND METHODS: A retrospective analysis was conducted on 73 patients with T1b glottic carcinoma. The patients were categorized into three groups: Group A ( n  = 22) underwent transoral laser microsurgery (TLMS), Group B ( n  = 21) received frontolateral vertical partial laryngectomy (FVPL), and Group C ( n  = 30) underwent HMPL-CTP...
October 14, 2023: Acta Oto-laryngologica
https://read.qxmd.com/read/37822063/role-of-endoscopy-in-gastroesophageal-reflux-disease
#17
REVIEW
Daniel Martin Simadibrata, Elvira Lesmana, Ronnie Fass
In general, gastroesophageal reflux disease (GERD) is diagnosed clinically based on typical symptoms and/or response to proton pump inhibitor treatment. Upper gastrointestinal endoscopy is reserved for patients presenting with alarm symptoms, such as dysphagia, odynophagia, significant weight loss, gastrointestinal bleeding, or anorexia; those who meet the criteria for Barrett's esophagus screening; those who report a lack or partial response to proton pump inhibitor treatment; and those with prior endoscopic or surgical anti-reflux interventions...
October 12, 2023: Clinical Endoscopy
https://read.qxmd.com/read/37785744/transoral-laser-microsurgery-and-radiotherapy-for-early-glottic-cancer-an-old-story-with-a-new-ending
#18
JOURNAL ARTICLE
J C Chien
PURPOSE/OBJECTIVE(S): Transoral laser microsurgery (TLM) and radiotherapy (RT) were stated equal in oncological outcome for early glottic cancer (EGC). But treatment rationale and cordectomy type might vary in TLM. We aimed to provide the clinical experience comparing TLM and RT in EGC. MATERIALS/METHODS: We retrospectively collected data of EGC from a medical center. Primary endpoint was local control (LC), defined as no in situ or invasive carcinoma found in the larynx after definitive treatment...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37772920/prospective-evaluation-and-validation-of-the-laryngoscore-and-the-mini-laryngoscore
#19
JOURNAL ARTICLE
Camille Clarysse, Jeroen Meulemans, Charlotte van Lierde, Annouschka Laenen, Pierre Delaere, Vincent Vander Poorten
OBJECTIVE: The Laryngoscore was described in 2014 as a practical preoperative assessment tool to predict difficult laryngeal exposure (DLE) during transoral approaches to the larynx. In 2019 the authors proposed a version with a reduced number of variables, called the mini-Laryngoscore. We aim to critically appraise and externally validate these two tools and if needed and possible, to optimize these tools. METHODS: 103 consecutive patients who underwent a microlaryngoscopy between November 2017 and June 2020 at the Leuven University Hospitals were prospectively included and subjected to a presurgical evaluation of 15 parameters and a peroperative scoring of the anterior commissure visualization...
September 29, 2023: Laryngoscope
https://read.qxmd.com/read/37740744/value-and-role-of-surgical-margins-in-transoral-laser-microsurgery-of-the-larynx-literature-review-and-clinical-considerations
#20
REVIEW
M Reale, M L Bardon, G Ciavarro, G Pedrazzi, G P Santoro
PURPOSE: There is no agreement on the most appropriate post-operative pathway for the management of positive margins after laser cordectomy for early stage glottic tumours (T1-2N0M0). This literature review and meta-analysis aim to evaluate the post-operative treatment with the best oncological results among follow-up, radiotherapy (RT) and surgical second look. The parameters utilized were incidence of recurrence, overall (OS), disease-specific (DSS) and disease-free (DFS) survival and larynx preservation (LP)...
September 23, 2023: European Archives of Oto-rhino-laryngology
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