keyword
MENU ▼
Read by QxMD icon Read
search

Oropharyngeal cancer

keyword
https://www.readbyqxmd.com/read/29044631/frailty-hospital-volume-and-failure-to-rescue-after-head-and-neck-cancer-surgery
#1
Carrie L Nieman, C Matthew Stewart, David W Eisele, Peter J Pronovost, Christine G Gourin
OBJECTIVES/HYPOTHESIS: We previously reported that high-volume hospital head and neck cancer (HNCA) surgical care is associated with decreased mortality, largely explained by reduced rates of failure to rescue. Frailty is an independent predictor of mortality, but is significantly less likely in patients receiving high-volume care. We investigate whether differences in frailty rates explain the relationship between volume and outcomes in HNCA patients and whether frailty confounds the relationship between failure to rescue and mortality...
October 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29044458/patient-reported-quality-of-life-outcomes-after-de-escalated-chemoradiation-for-human-papillomavirus-positive-oropharyngeal-carcinoma-findings-from-a-phase-2-trial
#2
John V Hegde, Narek Shaverdian, Megan E Daly, Carol Felix, Deborah L Wong, Michael H Rosove, Jordan H Garst, Pin-Chieh Wang, Darlene Veruttipong, Shyam Rao, Ruben C Fragoso, Jonathan W Riess, Michael L Steinberg, Allen M Chen
BACKGROUND: The current study represents a subset analysis of quality-of-life (QOL) outcomes among patients treated on a phase 2 trial of de-escalated chemoradiation for human papillomavirus (HPV)-associated oropharyngeal cancer. METHODS: Eligibility included newly diagnosed, (American Joint Committee on Cancer, 7th edition) stage III or IV oropharyngeal squamous cell carcinoma, p16 positivity, age ≥ 18 years, and a Zubrod performance status of 0 to 1. Treatment was induction paclitaxel at a dose of 175 mg/m(2) and carboplatin at an area under the curve of 6 for 2 cycles followed by response-adapted, dose-reduced radiation of 54 Gy or 60 Gy with weekly concurrent paclitaxel at a dose of 30 mg/m(2) ...
October 17, 2017: Cancer
https://www.readbyqxmd.com/read/29039250/predictors-of-clinicopathologic-stage-discrepancy-in-oropharyngeal-squamous-cell-carcinoma-a-national-cancer-database-study
#3
Suat Kılıç, Sarah S Kılıç, Kajal P Shah, Jean Anderson Eloy, Soly Baredes, Omar M Mahmoud, Richard Chan Woo Park
Objective To determine the frequency, associated factors, and prognosis of clinicopathologic stage discrepancy in oropharyngeal squamous cell carcinoma (OPSCC). Study Design Retrospective study using a national database. Setting National Cancer Database. Subjects and Methods Cases of OPSCC diagnosed between January 1, 2004, and December 31, 2013, with full clinical and pathologic staging information available were identified. Demographic, clinicopathologic, and treatment variables associated with overall stage discrepancy were identified by multivariate logistic regression analysis...
October 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29037233/cancer-incidence-in-germany-attributable-to-human-papillomavirus-in-2013
#4
Nina Buttmann-Schweiger, Yvonne Deleré, Stefanie J Klug, Klaus Kraywinkel
BACKGROUND: It is estimated that a total of 120,000 new cancer cases in men and in women in more developed countries could be avoided if exposure to HPV was prevented. We used the nationwide pool of German population-based cancer registry data to estimate the burden of HPV-attributable cancer in this population for the year 2013. METHODS: Incident cases of cervical cancer, squamous cell carcinoma of the anus, oropharynx (OP), as well as of the vulva, vagina and penis were classified as potentially HPV-associated and identified from the nationwide cancer registry data-pool...
October 16, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29037027/refining-prognostic-stratification-of-human-papillomavirus-related-oropharyngeal-squamous-cell-carcinoma-different-prognosis-between-t1-and-t2
#5
Sumin Lee, Sang-Wook Lee, Sunmin Park, Sang Min Yoon, Jin-Hong Park, Si Yeol Song, Seung Do Ahn, Jong Hoon Kim, Eun Kyung Choi, Su Ssan Kim, Jinhong Jung, Young Seok Kim
PURPOSE: To validate the 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system for human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) and investigate whether a modified classification better reflects the prognosis. MATERIALS AND METHODS: Medical records of patients diagnosed with non-metastatic HPV-related OPSCC between 2010 and 2016 at a single institution were retrospectively reviewed...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29031503/assessing-dentists-human-papillomavirus-related-health-literacy-for-oropharyngeal-cancer-prevention
#6
Coralia Vázquez-Otero, Cheryl A Vamos, Erika L Thompson, Laura K Merrell, Stacey B Griner, Nolan S Kline, Frank A Catalanotto, Anna R Giuliano, Ellen M Daley
BACKGROUND: Oropharyngeal cancers related to human papillomavirus (HPV) are on the rise. Dentists may be the next group of providers participating in the prevention of HPV. The aim of this study was to assess dentists' health literacy regarding the connection of HPV and oropharyngeal cancer. METHODS: The authors conducted 4 focus groups with dentists (N = 33) during a regional dental conference in 2016. Guided by the health literacy competencies (that is, access, understand, appraise, and apply), the authors used constant comparison methods for data analysis...
October 12, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29029021/aetiological-heterogeneity-of-head-and-neck-squamous-cell-carcinomas-the-role-of-human-papillomavirus-infections-smoking-and-alcohol
#7
Nada J Farsi, Marie-Claude Rousseau, Nicolas Schlecht, Geneviève Castonguay, Paul Allison, Phuc Félix Nguyen-Tan, Denis Soulieres, Francois Coutlée, Michael Hier, Sreenath Madathil, Eduardo L Franco, Belinda Nicolau
Tobacco and alcohol consumption are the main risk factors for head and neck squamous cell carcinoma (HNSCC). In addition, human papillomavirus (HPV) infection plays a causal role in oropharyngeal cancer (OPC), a subset of HNSCC. We assessed the independent effects of tobacco, alcohol, and HPV infection on OPC risk in the Head and Neck Cancer(HeNCe) Life study, a hospital-based case-control study of HNSCC with frequency-matched controls by age and sex from four Montreal hospitals. Interviewers collected information on socio-demographic and behavioural factors...
September 28, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29025723/setting-the-stage-for-2018-how-the-changes-in-the-american-joint-committee-on-cancer-union-for-international-cancer-control-cancer-staging-manual-eighth-edition-impact-radiologists
#8
C M Glastonbury, S K Mukherji, B O'Sullivan, W M Lydiatt
The updated eighth edition of the Cancer Staging Manual of the American Joint Committee on Cancer will be implemented in January 2018. There are multiple changes to the head and neck section of the manual, which will be relevant to radiologists participating in multidisciplinary head and neck tumor boards and reading pretreatment head and neck cancer scans. Human papillomavirus-related/p16(+) oropharyngeal squamous cell carcinoma will now be staged separately; this change reflects the markedly better prognosis of these tumors compared with non-human papillomavirus/p16(-) oropharyngeal squamous cell carcinoma...
October 12, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29024186/fear-of-cancer-recurrence-in-oral-and-oropharyngeal-cancer-patients-an-investigation-of-the-clinical-encounter
#9
G Ozakinci, B Swash, G Humphris, S N Rogers, N J Hulbert-Williams
Fear of cancer recurrence (FCR) is common among individuals treated for cancer. Explorations of how this fear is expressed within an oncology setting and responded to are currently lacking. The aim was to investigate how head and neck cancer survivors in follow-up consultations express FCR, investigate how a healthcare professional addresses recurrence fears, and examine how survivors experience this interaction. We recorded the follow-up consultations of those participants who have reported FCR as a concern on the Patient Concerns Inventory...
October 12, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/29024178/familial-clustering-of-oropharyngeal-squamous-cell-carcinoma-in-the-utah-population
#10
Marcus M Monroe, Mia Hashibe, Quinn Orb, Jeremiah Alt, Luke Buchmann, Jason Hunt, Lisa A Cannon-Albright
BACKGROUND: The main purpose of the current study was to define the familial aggregation of oropharyngeal squamous cell carcinoma (SCC) and risk to relatives of patients with oropharyngeal SCC. METHODS: We conducted a retrospective study utilizing linked population-based genealogy and state cancer registry databases between 1966 and 2012. Relative risks for oropharyngeal SCC and other malignancies among patients with oropharyngeal SCC and their relatives were estimated...
October 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/29018052/intratumoral-hpv16-specific-t-cells-constitute-a-type-1-oriented-tumor-microenvironment-to-improve-survival-in-hpv16-driven-oropharyngeal-cancer
#11
Marij J P Welters, Wenbo Ma, Saskia J Santegoets, Renske Goedemans, Ilina Ehsan, Katja S Jordanova, Vanessa J van Ham, Vincent van Unen, Frits Koning, Sylvia I van Egmond, Pornpimol Charoentong, Zlatko Trajanoski, Lilly-Ann van der Velden, Sjoerd H van der Burg
PURPOSE: Human papilloma virus (HPV)-associated oropharyngeal squamous cell cancer (OPSCC) has a much better prognosis than HPV-negative OPSCC and this is linked to dense tumor immune infiltration. Since the viral antigens may trigger potent immunity, we studied the relationship between the presence of intratumoral HPV-specific T-cell responses, the immune contexture in tumor microenvironment and clinical outcome. EXPERIMENTAL DESIGN: To this purpose an in-depth analysis of tumor-infiltrating immune cells in a prospective cohort of 97 HPV16-positive and -negative OPSCC patients was performed using functional T-cell assays, mass cytometry (CyTOF), flow cytometry and fluorescent immunostaining of tumor tissues...
October 10, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28990700/application-of-the-eighth-edition-american-joint-committee-on-cancer-staging-system-for-hpv-related-oropharyngeal-cancer-treated-with-transoral-robotic-surgery
#12
Arvind K Badhey, Ashley Olson, Sameep Kadakia, Jack Russo, Peter Ting, Mian Khalid, Mike Yao, Marita S Teng, Eric M Genden, Brett A Miles, Raymond L Chai
OBJECTIVE: Analyze patients treated with transoral robotic surgery (TORS) in the context of the eighth edition of the American Joint Committee on Cancer (AJCC) staging system. METHODS: Retrospective cohort study including 110 human papillomavirus-related oropharyngeal cancer (HPV+OPC) patients with a minimum 1-year follow-up treated with TORS between 2007 to 2016. Kaplan-Meier methods were used to estimate 3-year disease-free survival and assess differences in recurrence...
October 9, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28990257/validation-of-the-eighth-edition-american-joint-committee-on-cancer-staging-system-for-human-papillomavirus-associated-oropharyngeal-cancer
#13
John D Cramer, Kate E Hicks, Alfred W Rademaker, Urjeet A Patel, Sandeep Samant
BACKGROUND: The eighth edition American Joint Committee on Cancer (AJCC) staging manual includes major changes in staging of oropharyngeal cancer (OPC). We evaluated the new staging system in order to validate this shift in classification. METHODS: We used the National Cancer Database (NCDB) to identify patients with human papillomavirus-associated (HPV-positive) OPC from 2010-2013. We restaged patients using the eighth edition guidelines and compared them with those from the seventh edition...
October 9, 2017: Head & Neck
https://www.readbyqxmd.com/read/28988705/implementing-head-and-neck-contouring-peer-review-without-pathway-delay-the-on-demand-approach
#14
C Fong, P Sanghera, J Good, P Nightingale, A Hartley
AIMS: Peer review of contour volume is a priority in the radiotherapy treatment quality assurance process for head and neck cancer. It is essential that incorporation of peer review activity does not introduce additional delays. An on-demand peer review process was piloted to assess the feasibility and efficiency of this approach, as compared with a historic scheduled weekly approach. MATERIALS AND METHODS: Between November 2016 and April 2017 four head and neck clinicians in one centre took part in an on-demand peer review process...
October 5, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28988469/treatment-survival-and-costs-of-oropharyngeal-cancer-care-in-the-elderly
#15
Christine G Gourin, Carole Fakhry, Harry Quon, Hyunseok Kang, Ana P Kiess, Robert J Herbert, David W Eisele, Kevin D Frick
OBJECTIVES/HYPOTHESIS: To examine associations between treatment, survival, and costs in elderly patients with oropharyngeal squamous cell cancer (OPSCC). STUDY DESIGN: Retrospective cross-sectional analysis of Surveillance, Epidemiology, and End Results-Medicare data. METHODS: We evaluated 666 patients diagnosed with OPSCC from 2004 to 2007 using cross-tabulations, multivariate logistic and generalized linear regression modeling, and survival analysis...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28988426/primary-surgery-versus-primary-radiation-based-treatment-for-locally-advanced-oropharyngeal-cancer
#16
Sophia C Kamran, Muhammad M Qureshi, Scharukh Jalisi, Andrew Salama, Gregory Grillone, Minh Tam Truong
OBJECTIVE: Randomized data comparing surgery to radiation for locally advanced oropharyngeal cancer (OPC) are lacking. This study evaluated practice patterns and overall survival outcomes from the National Cancer Database. METHODS: A total of 22,676 patients with stage III to IV, locally advanced OPC were treated between 2004 to 2013 with primary chemoradiation (CRT) or surgery with adjuvant radiotherapy with or without chemotherapy (aRT ± CT). Survival rates were estimated using the Kaplan-Meier method...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28980780/-changes-in-the-new-tnm-classification-in-head-and-neck-oncology
#17
Silvia Lambiel, Pavel Dulguerov
The Union for International Cancer Control (UICC) published in 2017 a revised 8th edition of the TNM classification bringing numerous changes in the classification of head and neck tumors. Three new entities were introduced, namely HPV-positive oropharyngeal carcinoma, neck metastasis from an unknown primary, and skin carcinoma of the head and neck. Going beyond the traditional size of the lesions, several new predictive factors have been included, such as the depth of invasion of oral carcinoma and the extracapsular spread of neck metastasis...
October 4, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28973501/chemo-selection-with-docetaxel-cisplatin-and-5-fluorouracil-tpf-regimen-followed-by-radiation-therapy-or-surgery-for-pharyngeal-and-laryngeal-carcinoma
#18
Takuma Matoba, Kei Ijichi, Takeshi Yanagi, Kayoko Kabaya, Daisuke Kawakita, Shintaro Beppu, Junichi Torii, Shingo Murakami
Background: Induction chemotherapy for patients with head and neck cancer is widely performed, and several advantages of induction chemotherapy have been reported. However, there is currently insufficient evidence to strongly recommend induction chemotherapy. In this study, we analyzed the outcomes for patients treated with induction chemotherapy and subsequent definitive treatments. Methods: Operable patients with untreated oropharyngeal, hypopharyngeal and laryngeal squamous cell carcinoma treated with induction chemotherapy were included in this retrospective study...
August 18, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28963823/predictors-of-contralateral-bilateral-nodal-disease-in-oropharyngeal-cancer-a-national-cancer-data-base-study
#19
Masanari G Kato, Mark A Ellis, Shaun A Nguyen, Terry A Day
BACKGROUND: Oropharyngeal squamous cell carcinoma (SCC) frequently presents with cervical metastasis. Roles of human papillomavirus (HPV) status, among other factors, on laterality are elusive. METHODS: The National Cancer Database was reviewed for oropharyngeal SCC diagnosed from 2010-2014. Predictors of clinically evident contralateral or bilateral nodal disease were identified. RESULTS: A total of 15 517 patients with oropharyngeal SCC met criteria...
September 30, 2017: Head & Neck
https://www.readbyqxmd.com/read/28963817/comparison-of-outcomes-with-extensive-segmental-pectoralis-major-myocutaneous-flap-via-the-anterior-axillary-line-and-the-conventional-technique-in-oral-and-oropharyngeal-cancer
#20
Wei-Liang Chen, Da-Ming Zhang, Zhi-Quan Huang, Yan Wang, Bin Zhou, You-Yuan Wang
BACKGROUND: This study compared the outcomes of an extensive segmental pectoralis major myocutaneous flap (esPMMF) and a conventional pectoralis major myocutaneous flap (PMMF). METHODS: The study enrolled 91 patients with primary oral and oropharyngeal squamous cell carcinoma (SCC) who underwent radical resection followed by reconstruction of the defect using either an esPMMF via the anterior axillary line or a PMMF. The pedicle lengths of the esPMMF and PMMF were 22-28 and 18-22 cm, respectively...
September 30, 2017: Head & Neck
keyword
keyword
4760
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"