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https://www.readbyqxmd.com/read/30017713/midterm-outcomes-after-arthroscopic-surgery-for-hypermobile-lateral-meniscus-in-adults-restriction-of-paradoxical-motion
#1
Tomoaki Kamiya, Tomoyuki Suzuki, Hidenori Otsubo, Miki Kuroda, Takashi Matsumura, Chihiro Kubota, Toshihiko Yamashita
BACKGROUND: Hypermobile lateral meniscus (HLM) is one of the causes of knee pain and a locking sensation. It is thought that disruption of the popliteomeniscle fascicles lead to hypermobility of the lateral meniscus in adults. In cases of HLM, the posterior portion of the lateral meniscus shows forward abnormal translation with knee flexion and backward translation with knee extension. We refer to this phenomenon as paradoxical motion. The purpose of this study was to report an arthroscopic HLM stabilization and evaluate the midterm clinical outcomes...
July 13, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29950777/hypermobile-ehlers-danlos-syndrome-and-rehabilitation-taking-stock-of-evidence-based-medicine-a-systematic-review-of-the-literature
#2
REVIEW
Bruno Corrado, Gianluca Ciardi
[Purpose] The aim of the study was to conduct a systematic review about rehabilitation treatment of hypermobile Ehlers-Danlos syndrome, according to Evidence Based Medicine. [Methods] A systematic search has been conducted in following database: PubMed, PEDro, Cochrane, EDS Base Index, TRIP and CINHAL; no time restrictions were adopted. PICO method was employed to formulate the clinical query. Hypermobile Ehlers-Danlos syndrome and physiotherapy were the main keywords of the research. [Results] 1,869 articles emerged from the primary search...
June 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29892537/widely-disseminated-sporadic-burkitt-lymphoma-initially-presented-as-oral-manifestations-in-a-6-year-old-boy
#3
Bong-Hae Cho, Dong-Hoon Shin, Yun-Hoa Jung, Hae-Ryoun Park
Burkitt lymphoma, a subtype of non-Hodgkin's lymphoma, is an aggressive neoplasm with three variants that are endemic, sporadic, and immunodeficiency associated. We present an unusual case of sporadic Burkitt lymphoma in a 6-year-old boy who initially presented with hypermobile teeth and no other specific signs or symptoms. On dental radiography, the patient was found to have alveolar bone resorption adjacent to the maxillary first molars, with the appearance of floating teeth. In addition, magnetic resonance imaging (MRI) showed extensive soft tissue masses involving four quadrants of the jaws...
May 2018: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/29843388/relationship-between-body-mass-index-cardiorespiratory-and-musculoskeletal-fitness-among-south-african-adolescent-girls
#4
Emmanuel Bonney, Gillian Ferguson, Bouwien Smits-Engelsman
Background : Cardiorespiratory and musculoskeletal fitness are important health indicators that support optimal physical functioning. Understanding the relationship between body mass index and these health markers may contribute to the development of evidence-based interventions to address obesity-related complications. The relationship between body mass index, cardiorespiratory and musculoskeletal fitness has not been well explored, particularly in female adolescents. The aim of this study was to investigate the association between body mass index, cardiorespiratory and musculoskeletal fitness among South African adolescent girls in low-income communities...
May 28, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29775909/sensorimotor-control-and-neuromuscular-activity-of-the-shoulder-in-adolescent-competitive-swimmers-with-generalized-joint-hypermobility
#5
Thomas Frydendal, Henrik Eshøj, Behnam Liaghat, Pascal Edouard, Karen Søgaard, Birgit Juul-Kristensen
INTRODUCTION: Shoulder pain is highly prevalent in competitive swimmers, and generalized joint hypermobility (GJH) is considered a risk factor. Sensorimotor control deficiencies and altered neuromuscular activation of the shoulder may represent underlying factors. RESEARCH QUESTION: To investigate whether competitive swimmers with GJH including shoulder hypermobility (GJHS) differ in shoulder sensorimotor control and muscle activity from those without GJH and no shoulder hypermobility (NGJH)...
June 2018: Gait & Posture
https://www.readbyqxmd.com/read/29669593/association-between-general-joint-hypermobility-and-knee-hip-and-lumbar-spine-osteoarthritis-by-race-a-cross-sectional-study
#6
Portia P E Flowers, Rebecca J Cleveland, Todd A Schwartz, Amanda E Nelson, Virginia B Kraus, Howard J Hillstrom, Adam P Goode, Marian T Hannan, Jordan B Renner, Joanne M Jordan, Yvonne M Golightly
BACKGROUND: Osteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and its relationship with knee, hip, and lumbar spine OA by race (African American vs. Caucasian). METHODS: Data were from the Johnston County OA project, collected 2003-2010. GJH was defined as Beighton score ≥4. OA symptoms were defined as the presence of pain, aching, or stiffness on most days separately at the knee, hip, and lower back...
April 18, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29666082/knee-joint-instability-after-total-knee-replacement-in-a-patient-with-ehlers-danlos-syndrome-the-role-of-insert-changes-as-practical-solution
#7
Ajmal Farid, Stefan Beekhuizen, Joris van der Lugt, Marijn Rutgers
Treatment of knee joint instability in patients with hypermobile Ehlers-Danlos syndrome (EDS) can be challenging. A 53-year-old woman with hypermobile EDS underwent bilateral total knee replacement (TKR) due to valgus osteoarthritis. During follow-up, she developed hypermobility of both knee replacements. Revision of the insert resolved the issue in her left knee; however, the right TKR required two insert exchanges and unfortunately instability persisted. Therefore, a revision to a constrained prosthesis was performed...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29587413/multifaced-roles-of-the-%C3%AE-v%C3%AE-3-integrin-in-ehlers-danlos-and-arterial-tortuosity-syndromes-dermal-fibroblasts
#8
REVIEW
Nicoletta Zoppi, Nicola Chiarelli, Marco Ritelli, Marina Colombi
The αvβ3 integrin, an endothelial cells' receptor-binding fibronectin (FN) in the extracellular matrix (ECM) of blood vessels, regulates ECM remodeling during migration, invasion, angiogenesis, wound healing and inflammation, and is also involved in the epithelial mesenchymal transition. In vitro-grown human control fibroblasts organize a fibrillar network of FN, which is preferentially bound on the entire cell surface to its canonical α5β1 integrin receptor, whereas the αvβ3 integrin is present only in rare patches in focal contacts...
March 26, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29576785/incidental-finding-of-a-large-mobile-aortic-arch-mass-during-conventional-angiography
#9
Hassan Aghajani, Shahrooz Yazdani, Mohammad Ghafaripoor, Zahra Shajari
Thromboembolism occurs commonly in general practice and leads to significant health burden. Apart from cardiac sources, aortic atherosclerotic plaques contribute considerably to thromboembolism. A 63-year-old diabetic hypertensive woman referred to our center due to exertional chest pain unresponsive to optimal medical therapy and underwent coronary angiography. Owing to resistance during guide-wire advancement, an aortography was performed. Aortic arch injection demonstrated a large suspended mass distal to the left subclavian artery with free movement in the descending thoracic aorta...
October 2017: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/29549458/gastrointestinal-symptoms-in-postural-tachycardia-syndrome-a-systematic-review
#10
REVIEW
Shahram E Mehr, Adrian Barbul, Cyndya A Shibao
Gastrointestinal symptoms are among the most common complaints in patients with postural tachycardia syndrome (POTS). In some cases, they dominate the clinical presentation and cause substantial disabilities, including significant weight loss and malnutrition, that require the use of invasive treatment to support caloric intake. Multiple cross-sectional studies have reported a high prevalence of gastrointestinal symptoms in POTS patients with connective tissue diseases, such as Ehlers-Danlos, hypermobile type, and in patients with evidence of autonomic neuropathy...
March 16, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29536137/-mediocarpal-instability-of-the-wrist
#11
REVIEW
A L Sander, K Sommer, K Eichler, I Marzi, J Frank
Typical lesions of the carpal ligaments are mostly found after a fall on the wrist in hyperextension or as complex injuries after severe trauma, e. g. after a fall from a significant height, motorcycle accident or as accompanying lesions in multiple trauma. The typical mechanisms, patterns and diagnostic algorithms are well known for the common ligamentous injuries (e.g. scapholunate, lunotriquetral and perilunate); therefore, consistent diagnostic procedures and adequate therapy are increasingly performed after such lesions, e...
May 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29517867/-severe-mast-cell-activation-syndrome-in-a-15-year-old-patient-with-an-hypermobile-ehlers-danlos-syndrome
#12
S Daens, D Grossin, T Hermanns-Lê, D Peeters, D Manicourt
We report the history of a 15-year old patient with a hypermobile Ehlers-Danlos syndrome (hEDS) (his mother, his two brothers and his sister have the same phenotype as him). He suffers mainly from a severe mast cell activation syndrome (MCAS) with an overreaction of the skin to any kind of contact (water of the shower, clothes, bed sheets) but he has also fatigue, headaches, and rash. This impressive rash is exacerbated after the shower and he has the urge to rest («shower's sign»). We describe the MCAS and its easy, fast and very effective medication management, without any significant side effects as well as its frequent association with the hEDS...
February 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29510315/the-upper-limb-hypermobility-assessment-tool-a-novel-validated-measure-of-adult-joint-mobility
#13
Leslie L Nicholson, Cliffton Chan
BACKGROUND: Existing measures of generalized joint hypermobility do not include commonly affected upper limb joints. OBJECTIVE: To evaluate the reliability of a novel clinically-applicable measure of upper limb joint mobility, its ability to discriminate between varying extents of hypermobility, identify generalized joint hypermobility, and to establish a cut-point for hypermobility classification. DESIGN: Validation of a diagnostic tool. METHOD: Participants were sought from three groups - healthy controls, likely and known hypermobiles, and assessed using the Upper Limb Hypermobility Assessment Tool (ULHAT), Beighton score and clinical opinion...
June 2018: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29497845/low-and-high-anxious-hypermobile-ehlers-danlos-syndrome-patients-comparison-of-psychosocial-and-health-variables
#14
Carolina Baeza-Velasco, Caroline Bourdon, Lucile Montalescot, Cécile de Cazotte, Guillem Pailhez, Antonio Bulbena, Claude Hamonet
Despite the frequent co-ocurrence of hypermobile Ehler-Danlos syndrome (hEDS) and pathological anxiety, little is known about the psychosocial and health implications of such comorbidity. Our aim was to explore the association between high levels of anxiety and psychosocial (catastrophizing, kinesiophobia, somatosensory amplification, social support and functioning), health (pain, fatigue, BMI, tobacco/alcohol use, depression, diagnosis delay, general health), and sociodemographic factors in people with hEDS...
May 2018: Rheumatology International
https://www.readbyqxmd.com/read/29446032/attention-deficit-hyperactivity-disorder-joint-hypermobility-related-disorders-and-pain-expanding-body-mind-connections-to-the-developmental-age
#15
REVIEW
Carolina Baeza-Velasco, Lorenzo Sinibaldi, Marco Castori
Attention-deficit/hyperactivity disorder (ADHD) and generalized joint hypermobility (JH) are two separated conditions, assessed, and managed by different specialists without overlapping interests. Recently, some researchers highlighted an unexpected association between these two clinical entities. This happens in a scenario of increasing awareness on the protean detrimental effects that congenital anomalies of the connective tissue may have on human health and development. To review pertinent literature to identify possible connections between ADHD and GJH, special emphasis was put on musculoskeletal pain and syndromic presentations of GJH, particularly the hypermobile Ehlers-Danlos syndrome...
February 14, 2018: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/29397244/cataract-in-a-patient-with-47-xyy-sex-chromosome-aneuploidy
#16
A Medina-Andrade, C Villanueva-Mendoza, S Arenas, V Cortés-González
CASE REPORT: The case concerns a 16 year-old boy with a history of high myopia and unilateral congenital cataract, tall stature for age, facial dysmorphism, hypermobile metacarpal-phalangeal joints, as well as behavioural problems. The mother had a history of recurrent pregnancy loss. Chromosomal analysis of the peripheral blood lymphocytes reported 47,XYY. DISCUSSION: Patients with sex chromosome aneuploidy 47,XYY have higher risk of congenital malformations, although ophthalmological anomalies are unusual...
June 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29357955/demographics-of-a-large-paediatric-postural-orthostatic-tachycardia-syndrome-program
#17
Jeffrey R Boris, Thomas Bernadzikowski
OBJECTIVE: The aim of this study was to identify and evaluate demographic and clinical features of paediatric patients with postural orthostatic tachycardia syndrome in a tertiary hospital speciality clinic. METHOD: This is a retrospective review of clinical data obtained during initial outpatient evaluation. RESULTS: A total of 708 patients met the evaluation criteria. Female patients outnumbered males, 3.45:1. Caucasians were over-represented at 94...
May 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29314775/the-relationship-between-digit-independence-and-digital-sesamoids-in-humans-and-a-proposal-of-a-new-digital-sesamoid-evolutionary-hypothesis
#18
Kaissar Yammine
Digital sesamoids are found in the metapodial-phalangeal joints of most mammals and quadrupedal tetrapods, yet their functional significance is still unclear. During primate evolution, a slight decline in their frequency has been associated with brachiation in gibbons, followed by a quasi-complete absence in orangutans then a slight resurgence occurred in gorillas and chimpanzees. Simultaneously, forearm muscles showed a progressive division in hominoid evolution towards a more "individualistic" musculature yielding more mobility and independence to some fingers...
June 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29309923/dermal-fibroblast-to-myofibroblast-transition-sustained-by-%C3%AE-v%C3%A3-3-integrin-ilk-snail1-slug-signaling-is-a-common-feature-for-hypermobile-ehlers-danlos-syndrome-and-hypermobility-spectrum-disorders
#19
Nicoletta Zoppi, Nicola Chiarelli, Silvia Binetti, Marco Ritelli, Marina Colombi
Hypermobile Ehlers-Danlos syndrome (hEDS) is a heritable connective tissue disorder with unknown molecular basis mainly characterized by generalized joint hypermobility, joint instability complications, and minor skin changes. The phenotypic spectrum is broad and includes multiple associated symptoms shared with chronic inflammatory systemic diseases. The stricter criteria defined in the 2017 EDS nosology leave without an identity many individuals with symptomatic joint hypermobility and/or features of hEDS; for these patients, the term Hypermobility Spectrum Disorders (HSD) was introduced...
April 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29212541/identifying-lower-limb-specific-and-generalised-joint-hypermobility-in-adults-validation-of-the-lower-limb-assessment-score
#20
Kaitlin J Meyer, Cliffton Chan, Luke Hopper, Leslie L Nicholson
BACKGROUND: The Lower Limb Assessment Score (LLAS) has only been validated in a paediatric population. The aim of this study was to validate the use of the LLAS in an adult population by: i) evaluating its ability to discriminate between different extents of lower limb hypermobility, ii) establishing a cut-off score to identify lower limb hypermobility, and iii) determining if the LLAS is able to identify Generalised Joint Hypermobility (GJH). METHODS: Participants were recruited across three groups representing varying degrees of hypermobility...
December 6, 2017: BMC Musculoskeletal Disorders
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