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https://www.readbyqxmd.com/read/28693622/prevention-and-treatment-of-long-term-social-disability-amongst-young-people-with-emerging-severe-mental-illness-with-social-recovery-therapy-the-prodigy-trial-study-protocol-for-a-randomised-controlled-trial
#1
David Fowler, Paul French, Robin Banerjee, Garry Barton, Clio Berry, Rory Byrne, Timothy Clarke, Rick Fraser, Brioney Gee, Kathryn Greenwood, Caitlin Notley, Sophie Parker, Lee Shepstone, Jon Wilson, Alison R Yung, Joanne Hodgekins
BACKGROUND: Young people who have social disability associated with severe and complex mental health problems are an important group in need of early intervention. Their problems often date back to childhood and become chronic at an early age. Without intervention, the long-term prognosis is often poor and the economic costs very large. There is a major gap in the provision of evidence-based interventions for this group, and therefore new approaches to detection and intervention are needed...
July 11, 2017: Trials
https://www.readbyqxmd.com/read/28560920/care-homes-needed-for-new-research-into-managing-falls
#2
Matthew Mckew
Academics conducting a £1.8 million research project are recruiting care homes to test a new falls procedure. Funded by the National Institute for Health Research, the three-year project involves trials of a new training package and guidelines designed by the University of Nottingham's Division of Rehabilitation and Ageing. The trials are taking place at residential and care homes in the East Midlands, West Yorkshire and East Anglia.
May 31, 2017: Nursing Older People
https://www.readbyqxmd.com/read/28541111/interprofessional-learning-benefits-for-healthcare-teams-and-patients
#3
Ruth Stone
Ruth Stone, a final-year student at the University of East Anglia, describes her experiences of attending conferences and workshops on interprofessional learning.
May 25, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28532503/an-updated-predict-breast-cancer-prognostication-and-treatment-benefit-prediction-model-with-independent-validation
#4
Francisco J Candido Dos Reis, Gordon C Wishart, Ed M Dicks, David Greenberg, Jem Rashbass, Marjanka K Schmidt, Alexandra J van den Broek, Ian O Ellis, Andrew Green, Emad Rakha, Tom Maishman, Diana M Eccles, Paul D P Pharoah
BACKGROUND: PREDICT is a breast cancer prognostic and treatment benefit model implemented online. The overall fit of the model has been good in multiple independent case series, but PREDICT has been shown to underestimate breast cancer specific mortality in women diagnosed under the age of 40. Another limitation is the use of discrete categories for tumour size and node status resulting in 'step' changes in risk estimates on moving between categories. We have refitted the PREDICT prognostic model using the original cohort of cases from East Anglia with updated survival time in order to take into account age at diagnosis and to smooth out the survival function for tumour size and node status...
May 22, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28485241/airport-security-rules-pose-risk-for-users-of-insulin-pumps
#5
(no author information available yet)
University of East Anglia child health nursing lecturer Katie McGhee has responded to a letter published in International Airport Review.
May 9, 2017: Nursing Children and Young People
https://www.readbyqxmd.com/read/28403876/development-of-a-core-outcome-set-for-effectiveness-trials-aimed-at-optimising-prescribing-in-older-adults-in-care-homes
#6
Anna N Millar, Amrit Daffu-O'Reilly, Carmel M Hughes, David P Alldred, Garry Barton, Christine M Bond, James A Desborough, Phyo K Myint, Richard Holland, Fiona M Poland, David Wright
BACKGROUND: Prescribing medicines for older adults in care homes is known to be sub-optimal. Whilst trials testing interventions to optimise prescribing in this setting have been published, heterogeneity in outcome reporting has hindered comparison of interventions, thus limiting evidence synthesis. The aim of this study was to develop a core outcome set (COS), a list of outcomes which should be measured and reported, as a minimum, for all effectiveness trials involving optimising prescribing in care homes...
April 12, 2017: Trials
https://www.readbyqxmd.com/read/28394249/cognitive-behavioural-therapy-and-short-term-psychoanalytic-psychotherapy-versus-brief-psychosocial-intervention-in-adolescents-with-unipolar-major-depression-impact-a-multicentre-pragmatic-observer-blind-randomised-controlled-trial
#7
Ian M Goodyer, Shirley Reynolds, Barbara Barrett, Sarah Byford, Bernadka Dubicka, Jonathan Hill, Fiona Holland, Raphael Kelvin, Nick Midgley, Chris Roberts, Rob Senior, Mary Target, Barry Widmer, Paul Wilkinson, Peter Fonagy
BACKGROUND: Although there are effective psychological treatments for unipolar major depression in adolescents, whether or not one or more of the available therapies maintain reduced depressive symptoms 1 year after the end of treatment is not known. This is a non-trivial issue because maintaining lowered depressive symptoms below a clinical threshold level reduces the risk for diagnostic relapse into the adult years. OBJECTIVE: To determine whether or not either of two specialist psychological treatments, cognitive-behavioural therapy (CBT) or short-term psychoanalytic psychotherapy (STPP), is more effective than a reference brief psychosocial intervention (BPI) in maintaining reduction of depression symptoms in the year after treatment...
March 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28293559/data-driven-risk-assessment-from-small-scale-epidemics-estimation-and-model-choice-for-spatio-temporal-data-with-application-to-a-classical-swine-fever-outbreak
#8
Kokouvi Gamado, Glenn Marion, Thibaud Porphyre
Livestock epidemics have the potential to give rise to significant economic, welfare, and social costs. Incursions of emerging and re-emerging pathogens may lead to small and repeated outbreaks. Analysis of the resulting data is statistically challenging but can inform disease preparedness reducing potential future losses. We present a framework for spatial risk assessment of disease incursions based on data from small localized historic outbreaks. We focus on between-farm spread of livestock pathogens and illustrate our methods by application to data on the small outbreak of Classical Swine Fever (CSF) that occurred in 2000 in East Anglia, UK...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28230436/the-research-nursing-team-providing-evidence-promoting-high-quality-care
#9
Ruth Stone
Ruth Stone, a final-year student at the University of East Anglia, discusses her first introduction to research nurses, and how this placement week will influence her approach to research in future.
February 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28124636/is-cestode-infection-intensity-associated-with-decreased-body-condition-in-the-eurasian-woodcock-scolopax-rusticola
#10
C Sánchez-García, E Harris, A C Deacon, R Bray, A N Hoodless
The Eurasian woodcock Scolopax rusticola is a widespread woodland specialist and a widely harvested quarry species throughout its European wintering areas, including Britain. Woodcock are prone to cestodiasis, but prevalence levels and possible effects on body condition remain under-studied. We studied the prevalence, abundance and intensity of cestodiasis in 161 woodcock harvested in four British regions in December and January during two consecutive winters (2013/14 and 2014/15). Cestodiasis prevalence was 90%, and there was no difference in prevalence between birds harvested in Cornwall, Wessex, East Anglia and Scotland...
January 26, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/27925545/sea-hero-quest
#11
REVIEW
(no author information available yet)
Sea Hero Quest has been developed to help fight dementia. The mobile game is a collaboration between Alzheimer's Research UK and scientists from University College London and the University of East Anglia.
December 7, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27834527/the-day-unit-holistic-care-in-action
#12
Ruth Stone
Ruth Stone, a final year student at the University of East Anglia, reflects on her placement in a day unit, where she saw patients receive a wide range of support and care, from blood transfusions to singing sessions.
November 10, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27821357/evaluation-of-meat-fruit-and-vegetables-from-retail-stores-in-five-united-kingdom-regions-as-sources-of-extended-spectrum-beta-lactamase-esbl-producing-and-carbapenem-resistant-escherichia-coli
#13
L P Randall, M P Lodge, N C Elviss, F L Lemma, K L Hopkins, C J Teale, N Woodford
We determined the prevalence and types of extended-spectrum β-lactamase (ESBL)-producing and carbapenem-resistant Escherichia coli in raw retail beef, chicken, pork, fruit and vegetables in five UK regions in 2013-14. Raw meat (n=397), and fruit and vegetable samples (n=400) were purchased from retail stores in London, East Anglia, North West England, Scotland and Wales. Samples were tested for the presence of ESBL-producing E. coli by plating enriched samples on CHROMagar CTX and CHROMagar ESBL, for AmpC-type E...
January 16, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27771972/the-epidemiology-of-first-episode-psychosis-in-early-intervention-in-psychosis-services-findings-from-the-social-epidemiology-of-psychoses-in-east-anglia-sepea-study
#14
James B Kirkbride, Yasir Hameed, Gayatri Ankireddypalli, Konstantinos Ioannidis, Carolyn M Crane, Mukhtar Nasir, Nikolett Kabacs, Antonio Metastasio, Oliver Jenkins, Ashkan Espandian, Styliani Spyridi, Danica Ralevic, Suneetha Siddabattuni, Ben Walden, Adewale Adeoye, Jesus Perez, Peter B Jones
OBJECTIVE: Few studies have characterized the epidemiology of first-episode psychoses in rural or urban settings since the introduction of early intervention psychosis services. To address this, the authors conducted a naturalistic cohort study in England, where such services are well established. METHOD: All new first-episode psychosis cases, 16-35 years old, presenting to early intervention psychosis services in the East of England were identified during 2 million person-years follow-up...
February 1, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/27677423/it-s-not-what-you-do-it-s-the-way-that-it-s-measured-quality-assessment-of-minor-ailment-management-in-community-pharmacies
#15
Jackie Inch, Terry Porteous, Vivienne Maskrey, Annie Blyth, Jackie Burr, Jennifer Cleland, David J Wright, Richard Holland, Christine M Bond, Margaret C Watson
BACKGROUND: Effective management of minor ailments in community pharmacies could reduce the burden on alternative high-cost services (general practices, Emergency Departments). Evidence is needed regarding the appropriateness of management of these conditions in community pharmacies. OBJECTIVE: To explore the appropriateness of minor ailment management in community pharmacies. SETTING: Prospective, observational study of simulated patient (SP) visits to community pharmacies in Grampian (Scotland) and East Anglia (England)...
September 28, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27618197/time-to-computerized-tomography-scan-age-and-mortality-in-acute-stroke
#16
MULTICENTER STUDY
Phyo Kyaw Myint, Andrew C Kidd, Chun Shing Kwok, Stanley D Musgrave, Oliver Redmayne, Anthony K Metcalf, Joseph Ngeh, Anne Nicolson, Peter Owusu-Agyei, Raj Shekhar, Kevin Walsh, Diana J Day, Elizabeth A Warburton, Max O Bachmann, John F Potter
BACKGROUND: Time to computerized tomography (CT) is important to institute appropriate and timely hyperacute management in stroke. We aimed to evaluate mortality outcomes in relation to age and time to CT scan. METHODS: We used routinely collected data in 8 National Health Service trusts in East of England between September 2008 and April 2011. Stroke cases were prospectively identified and confirmed. Odds ratios (ORs) for unadjusted and adjusted models for age categories (<65, 65-74, 75-84, and ≥85 years) as well as time to CT categories (<90 minutes, ≥90 to <180 minutes, ≥180 minutes to 24 hours, and >24 hours) and in-hospital and early (<7 days) mortality outcomes were calculated...
December 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27523766/self-development-and-earning-that-staff-nurse-uniform
#17
Ruth Stone
Ruth Stone, Second-year student at the University of East Anglia, reflects on her past 2 years as a nursing student and considers what she has ahead of her in her final year of study.
August 11, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27241345/the-potential-for-deprescribing-in-care-home-residents-with-type-2-diabetes
#18
Lillan Mo Andreassen, Reidun Lisbet Skeide Kjome, Una Ørvim Sølvik, Julie Houghton, James Antony Desborough
Background Type 2 diabetes is a common diagnosis in care home residents that is associated with potentially inappropriate prescribing and thus risk of additional suffering. Previous studies found that diabetes medicines can be safely withdrawn in care home residents, encouraging further investigation of the potential for deprescribing amongst these patients. Objectives Describe comorbidities and medicine use in care home residents with Type 2 diabetes; identify number of potentially inappropriate medicines prescribed for these residents using a medicines optimisation tool; assess clinical applicability of the tool...
August 2016: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/27208206/new-paradigms-for-brca1-brca2-testing-in-women-with-ovarian-cancer-results-of-the-genetic-testing-in-epithelial-ovarian-cancer-gteoc-study
#19
Inga Plaskocinska, Hannah Shipman, James Drummond, Edward Thompson, Vanessa Buchanan, Barbara Newcombe, Charlotte Hodgkin, Elisa Barter, Paul Ridley, Rita Ng, Suzanne Miller, Adela Dann, Victoria Licence, Hayley Webb, Li Tee Tan, Margaret Daly, Sarah Ayers, Barnaby Rufford, Helena Earl, Christine Parkinson, Timothy Duncan, Mercedes Jimenez-Linan, Gurdeep S Sagoo, Stephen Abbs, Nicholas Hulbert-Williams, Paul Pharoah, Robin Crawford, James D Brenton, Marc Tischkowitz
BACKGROUND: Over recent years genetic testing for germline mutations in BRCA1/BRCA2 has become more readily available because of technological advances and reducing costs. OBJECTIVE: To explore the feasibility and acceptability of offering genetic testing to all women recently diagnosed with epithelial ovarian cancer (EOC). METHODS: Between 1 July 2013 and 30 June 2015 women newly diagnosed with EOC were recruited through six sites in East Anglia, UK into the Genetic Testing in Epithelial Ovarian Cancer (GTEOC) study...
October 2016: Journal of Medical Genetics
https://www.readbyqxmd.com/read/27191657/an-update-on-the-clinical-utility-of-the-children-s-post-traumatic-cognitions-inventory
#20
Anna McKinnon, Patrick Smith, Richard Bryant, Karen Salmon, William Yule, Tim Dalgleish, Clare Dixon, Reginald D V Nixon, Richard Meiser-Stedman
The Children's Post-Traumatic Cognitions Inventory (CPTCI) is a self-report questionnaire that measures maladaptive cognitions in children and young people following exposure to trauma. In this study, the psychometric properties of the CPTCI were examined in further detail with the objective of furthering its utility as a clinical tool. Specifically, we investigated the CPTCI's discriminant validity, test-retest reliability, and the potential for the development of a short form of the measure. Three samples (London, East Anglia, Australia) of children and young people exposed to trauma (N = 535; 7-17 years old) completed the CPTCI and a structured clinical interview to measure posttraumatic stress disorder (PTSD) symptoms between 1 and 6 months following trauma...
June 2016: Journal of Traumatic Stress
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