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Transcranial alternating current stimulation

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https://www.readbyqxmd.com/read/29021749/phase-dependent-modulation-of-signal-transmission-in-cortical-networks-through-tacs-induced-neural-oscillations
#1
Kristoffer D Fehér, Masahito Nakataki, Yosuke Morishima
Oscillatory neural activity is considered a basis of signal transmission in brain networks. However, the causal role of neural oscillations in regulating cortico-cortical signal transmission has so far not been directly demonstrated. To date, due to methodological limitations, studies on the online modulatory mechanisms of transcranial alternating current stimulation (tACS)-induced neural oscillations are confined to the primary motor cortex. To address the causal role of oscillatory activity in modulating cortico-cortical signal transmission, we have established a new method using concurrent tACS, transcranial magnetic stimulation (TMS) and electroencephalography (EEG)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29018896/hypericum-perforatum-extract-modulates-cortical-plasticity-in-humans
#2
Carmen Concerto, Hyunji Boo, Charles Hu, Priam Sandilya, Anita Krish, Eileen Chusid, Diego Coira, Eugenio Aguglia, Fortunato Battaglia
BACKGROUND: Hypericum perforatum (HYP) extract is one of the most commonly used complementary alternative medicines (CAMs) for the treatment of mild-to-moderate depression. Non-invasive brain stimulation protocols can be used to investigate the effect of psychoactive substances on the human brain. In this study, we explored the effect of a single dose of HYP extract (WS 5570) intake on corticospinal excitability and plasticity in humans. METHODS: Twenty-eight healthy subjects were required to intake 900 mg of either HYP extract or placebo...
October 10, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28994763/effects-of-transcranial-alternating-current-stimulation-on-the-primary-motor-cortex-by-online-combined-approach-with-transcranial-magnetic-stimulation
#3
Anna Shpektor, Maria Nazarova, Matteo Feurra
Transcranial Alternating Current Stimulation (tACS) is a neuromodulatory technique able to act through sinusoidal electrical waveforms in a specific frequency and in turn modulate ongoing cortical oscillatory activity. This neurotool allows the establishment of a causal link between endogenous oscillatory activity and behavior. Most of the tACS studies have shown online effects of tACS. However, little is known about the underlying action mechanisms of this technique because of the AC-induced artifacts on Electroencephalography (EEG) signals...
September 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28987994/after-effects-of-transcranial-alternating-current-stimulation-on-evoked-delta-and-theta-power
#4
Miles Wischnewski, Dennis J L G Schutter
OBJECTIVE: Phase synchronization is suggested to be among the mechanisms that can explain the effects of transcranial alternating current stimulation (tACS). However, little is known about the effects of tACS on event-related oscillatory activity. Therefore the objective was to investigate frequency-related effects of frontal tACS on event-related oscillatory power. METHODS: In a double blind randomized controlled cross-over design, twenty-four participants received 12min of delta (2...
September 21, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28984619/the-therapeutic-use-of-non-invasive-brain-stimulation-in-multiple-sclerosis-a-review
#5
Rosa Iodice, Fiore Manganelli, Raffaele Dubbioso
BACKGROUND: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system and a leading cause of disability in young adults. Many disabling symptoms in MS, such as spasticity, pain, depression and cognitive deficits are not fully controlled by drug treatment. Non-invasive brain stimulation (NIBS) techniques can be used as tools for modulating altered cortical excitability and plasticity MS patients, providing an improvement in disabling symptoms affecting such patients...
2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28966091/modulation-of-long-range-connectivity-patterns-via-frequency-specific-stimulation-of-human-cortex
#6
Christiane A Weinrich, John-Stuart Brittain, Magdalena Nowak, Reza Salimi-Khorshidi, Peter Brown, Charlotte J Stagg
There is increasing interest in how the phase of local oscillatory activity within a brain area determines the long-range functional connectivity of that area. For example, increasing convergent evidence from a range of methodologies suggests that beta (20 Hz) oscillations may play a vital role in the function of the motor system [1-5]. The "communication through coherence" hypothesis posits that the precise phase of coherent oscillations in network nodes is a determinant of successful communication between them [6, 7]...
October 9, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28961738/cognitive-rehabilitation-in-parkinson-s-disease-is-it-feasible
#7
Roberta Biundo, Luca Weis, Eleonora Fiorenzato, Antonini Angelo
Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor and non-motor symptoms. Dementia is one of the most relevant non-motor symptoms considering its functional affect on PD patients' activities of daily living and family members' wellbeing. Cognitive abnormalities in PD are heterogeneous and reliable biomarkers to detect patients at risk for dementia early on remain to be identified. Pharmacological treatments specifically for PD dementia and mild cognitive impairment are lacking, and alternative approaches have recently been implemented, including cognitive rehabilitation...
September 18, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28955211/influence-of-concurrent-finger-movements-on-transcranial-direct-current-stimulation-tdcs-induced-aftereffects
#8
Yuichiro Shirota, Daniella Terney, Andrea Antal, Walter Paulus
Transcranial direct current stimulation (tDCS) has been reported to have bidirectional influence on the amplitude of motor-evoked potentials (MEPs) in resting participants in a polarity-specific manner: anodal tDCS increased and cathodal tDCS decreased them. More recently, the effects of tDCS have been shown to depend on a number of additional factors. We investigated whether a small variety of movements involving target and non-target muscles could differentially modify the efficacy of tDCS. MEPs were elicited from the right first dorsal interosseous muscle, defined as the target muscle, by single pulse transcranial magnetic stimulation (TMS) over the primary motor cortex (M1)...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28953851/is-there-potential-for-repetitive-transcranial-magnetic-stimulation-rtms-as-a-treatment-of-ocd
#9
Rashid Zaman, Trevor W Robbins
Obsessive-Compulsive Disorder (OCD) is a common and highly debilitating psychiatric disorder. Amongst OCD sufferers are a significant number (40-60%) of so-called non-responders who do not fully respond to commonly available treatments, which include medications (Selective Serotonin Reuptake Inhibitors-SSRIs) and cognitive behavior therapy (CBT). Modern 'neuromodulatory' techniques such as Deep Brain Stimulation (DBS), repetitive Transcranial Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS) potentially offer alternative forms of treatment for OCD patients who either do not respond to, or are unable or unwilling to take SSRIs and undergo CBT...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28937993/anaesthesia-not-number-of-sessions-influences-the-magnitude-and-duration-of-an-ahf-rtms-in-dogs
#10
Robrecht Dockx, Kathelijne Peremans, Lise Vlerick, Nick Van Laeken, Jimmy H Saunders, Ingeborgh Polis, Filip De Vos, Chris Baeken
BACKGROUND: Currently, the rat has been a useful animal model in brain stimulation research. Nevertheless, extrapolating results from rodent repetitive Transcranial Magnetic Stimulation (rTMS) research to humans contains several hurdles. This suggests the desperate need for a large animal model in translational rTMS research. The dog would be a valid choice, not only due to the fact that humans and dogs share a neurophysiological background, but a similar neuropathological background as well...
2017: PloS One
https://www.readbyqxmd.com/read/28928634/transcranial-alternating-current-stimulation-tacs-mechanisms-and-protocols
#11
REVIEW
Amir V Tavakoli, Kyongsik Yun
Perception, cognition and consciousness can be modulated as a function of oscillating neural activity, while ongoing neuronal dynamics are influenced by synaptic activity and membrane potential. Consequently, transcranial alternating current stimulation (tACS) may be used for neurological intervention. The advantageous features of tACS include the biphasic and sinusoidal tACS currents, the ability to entrain large neuronal populations, and subtle control over somatic effects. Through neuromodulation of phasic, neural activity, tACS is a powerful tool to investigate the neural correlates of cognition...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28919407/how-to-target-inter-regional-phase-synchronization-with-dual-site-transcranial-alternating-current-stimulation
#12
Guilherme Bicalho Saturnino, Kristoffer Hougaard Madsen, Hartwig Roman Siebner, Axel Thielscher
Large-scale synchronization of neural oscillations is a key mechanism for functional information exchange among brain areas. Dual-site Transcranial Alternating Current Stimulation (ds-TACS) has been recently introduced as non-invasive technique to manipulate the temporal phase relationship of local oscillations in two connected cortical areas. While the frequency of ds-TACS is matched, the phase of stimulation is either identical (in-phase stimulation) or opposite (anti-phase stimulation) in the two cortical target areas...
September 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/28912159/oscillatory-reinstatement-enhances-declarative-memory
#13
Amir-Homayoun Javadi, James C Glen, Sara Halkiopoulos, Mei Schulz, Hugo J Spiers
Declarative memory recall is thought to involve the reinstatement of neural activity patterns that occurred previously during encoding. Consistent with this view, greater similarity between patterns of activity recorded during encoding and retrieval has been found to predict better memory performance in a number of studies. Recent models have argued that neural oscillations may be crucial to reinstatement for successful memory retrieval. However, to date, no causal evidence has been provided to support this theory, nor has the impact of oscillatory electrical brain stimulation during encoding and retrieval been assessed...
October 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28890693/modulation-of-somatosensory-alpha-rhythm-by-transcranial-alternating-current-stimulation-at-mu-frequency
#14
Christopher Gundlach, Matthias M Müller, Till Nierhaus, Arno Villringer, Bernhard Sehm
Introduction: Transcranial alternating current stimulation (tACS) is emerging as an interventional tool to modulate different functions of the brain, potentially by interacting with intrinsic ongoing neuronal oscillations. Functionally different intrinsic alpha oscillations are found throughout the cortex. Yet it remains unclear whether tACS is capable of specifically modulating the somatosensory mu-rhythm in amplitude. Objectives: We used tACS to modulate mu-alpha oscillations in amplitude. When compared to sham stimulation we expected a modulation of mu-alpha oscillations but not visual alpha oscillations by tACS...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28889119/sham-transcranial-electrical-stimulation-and-its-effects-on-corticospinal-excitability-a-systematic-review-and-meta-analysis
#15
Thusharika D Dissanayaka, Maryam Zoghi, Michael Farrell, Gary F Egan, Shapour Jaberzadeh
Sham stimulation is used in randomized controlled trials (RCTs) to assess the efficacy of active stimulation and placebo effects. It should mimic the characteristics of active stimulation to achieve blinding integrity. The present study was a systematic review and meta-analysis of the published literature to identify the effects of sham transcranial electrical stimulation (tES) - including anodal and cathodal transcranial direct current stimulation (a-tDCS, c-tDCS), transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS) and transcranial pulsed current stimulation (tPCS) - on corticospinal excitability (CSE), compared to baseline in healthy individuals...
September 11, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28888892/alpha-band-transcranial-alternating-current-stimulation-modulates-precision-but-not-gain-during-whole-body-spatial-updating
#16
T P Gutteling, D J L G Schutter, W P Medendorp
Spatial updating is essential to maintain an accurate representation of our visual environment when we move. A neural mechanism that contributes to this ability is called remapping: the transfer of visual information from neural populations that code a location before the motion to those that encode it after the motion. While there is ample evidence for neural remapping in conjunction with eye movements, only recent findings suggest a role of this mechanism for whole-body motion updating, based on the observation that alpha band (10Hz) activity is selectively reorganized during remapping...
September 6, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28886918/complementary-and-alternative-therapies-for-restless-legs-syndrome-an-evidence-based-systematic-review
#17
REVIEW
Xiao-Min Xu, Yang Liu, Shi-Yu Jia, Mei-Xue Dong, Du Cao, You-Dong Wei
Restless legs syndrome (RLS) is defined as an irresistible urge to move the legs, which is usually accompanied by paresthesias or dysesthesias at least twice weekly, and affects 2%-4% of adults in Europe and North America. This systematic review assesses the current complementary and alternative options for RLS and the potential benefits of those treatments on sleep quality, mood disorder, and quality of life. A systematic search of the PubMed, Embase, Cochrane, and Web of Science databases was conducted. Eighteen studies met the inclusion criterion, which included the use of the international RLS study group criteria...
June 19, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28874923/noninvasive-brain-stimulation-maladaptive-plasticity-and-bayesian-analysis-in-phantom-limb-pain
#18
REVIEW
Leon Morales-Quezada
Introduction: Phantom limb pain (PLP) is a common and poorly understood pathology of difficult medical control that progressively takes place after amputation occurs. Objective: This article discusses the multifactorial bases of PLP. These bases involve local changes at the stump level, spinal modifications of excitability, deafferentation, and central sensitization, leading to the development of maladaptive plasticity, and consequentially, defective processing of sensory information by associative neural networks...
August 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/28822321/neurostimulation-techniques-in-the-treatment-of-cocaine-dependence-a-review-of-the-literature
#19
REVIEW
Fady Rachid
OBJECTIVE: Cocaine use disorder is a very common condition that represents a substantial public health problem, and no effective pharmacological or psychological therapies have been identified to date. Urgent therapeutic alternatives are therefore needed such as neurostimulation techniques. The purpose of this review is to describe and discuss studies that have evaluated the safety and efficacy of these techniques for the treatment of cocaine dependence. METHODS: The electronic literature on repetitive transcranial magnetic stimulation, theta-burst stimulation, deep transcranial magnetic stimulation, transcranial direct current stimulation, magnetic seizure therapy, electroconvulsive therapy, cranial electro-stimulation, and deep brain stimulation in the treatment of cocaine addiction were reviewed...
January 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/28804455/comparison-of-the-long-term-effect-of-positioning-the-cathode-in-tdcs-in-tinnitus-patients
#20
Sarah Rabau, Giriraj S Shekhawat, Mohamed Aboseria, Daniel Griepp, Vincent Van Rompaey, Marom Bikson, Paul Van de Heyning
Objective: Transcranial direct current stimulation (tDCS) is one of the methods described in the literature to decrease the perceived loudness and distress caused by tinnitus. However, the main effect is not clear and the number of responders to the treatment is variable. The objective of the present study was to investigate the effect of the placement of the cathode on the outcome measurements. Methods: Patients considered for the trial were chronic non-pulsatile tinnitus patients with complaints for more than 3 months and a Tinnitus Functional Index (TFI) score that exceeded 25...
2017: Frontiers in Aging Neuroscience
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