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Transcranial alternating current stimulation

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https://www.readbyqxmd.com/read/28642729/inconsistent-effects-of-parietal-%C3%AE-tacs-on-pseudoneglect-across-two-experiments-a-failed-internal-replication
#1
Domenica Veniero, Christopher S Y Benwell, Merle M Ahrens, Gregor Thut
Transcranial electrical stimulation (tES) is being investigated as an experimental and clinical interventional technique in human participants. While promising, important limitations have been identified, including weak effect sizes and high inter- and intra-individual variability of outcomes. Here, we compared two "inhibitory" tES-techniques with supposedly different mechanisms of action as to their effects on performance in a visuospatial attention task, and report on a direct replication attempt. In two experiments, 2 × 20 healthy participants underwent tES in three separate sessions testing different protocols (10 min stimulation each) with a montage targeting right parietal cortex (right parietal-left frontal, electrode-sizes: 3cm × 3cm-7 cm × 5 cm), while performing a perceptual line bisection (landmark) task...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28629447/transcranial-direct-current-stimulation-for-depression-in-alzheimer-s-disease-study-protocol-for-a-randomized-controlled-trial
#2
Zui Narita, Yuma Yokoi
BACKGROUND: Patients with Alzheimer's disease frequently elicit neuropsychiatric symptoms as well as cognitive deficits. Above all, depression is one of the most common neuropsychiatric symptoms in Alzheimer's disease but antidepressant drugs have not shown significant beneficial effects on it. Moreover, electroconvulsive therapy has not ensured its safety for potential severe adverse events although it does show beneficial clinical effect. Transcranial direct current stimulation can be the safe alternative of neuromodulation, which applies weak direct electrical current to the brain...
June 19, 2017: Trials
https://www.readbyqxmd.com/read/28620215/theta-band-transcranial-alternating-current-stimulations-modulates-network-behavior-of-dorsal-anterior-cingulate-cortex
#3
Keiichi Onoda, Toshikazu Kawagoe, Haixia Zheng, Shuhei Yamaguchi
Dorsal anterior cingulate cortex (dACC) is an important region in the processing of both cognition and affect. Recently, transcranial brain stimulation has been used to modulate cortical activity, but it is unclear whether this stimulation has a specific effect on dACC. Based on EEG evidence that frontal midline theta activity is generated in dACC, we hypothesized that transcranial alternating current stimulation (tACS) with theta band frequency would modulate neural networks including dACC. In this study, we examined the effects of theta band tACS on functional networks and emotional state...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28605386/simultaneous-transcranial-alternating-current-stimulation-and-functional-magnetic-resonance-imaging
#4
Kathleen A Williams, Yuranny Cabral-Calderin, Carsten Schmidt-Samoa, Christiane Anne Weinrich, Peter Dechent, Melanie Wilke
Transcranial alternating current stimulation (tACS) is a promising tool for noninvasive investigation of brain oscillations. TACS employs frequency-specific stimulation of the human brain through current applied to the scalp with surface electrodes. Most current knowledge of the technique is based on behavioral studies; thus, combining the method with brain imaging holds potential to better understand the mechanisms of tACS. Because of electrical and susceptibility artifacts, combining tACS with brain imaging can be challenging, however, one brain imaging technique that is well suited to be applied simultaneously with tACS is functional magnetic resonance imaging (fMRI)...
June 5, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28572761/ten-minutes-of-%C3%AE-tacs-and-ambient-illumination-independently-modulate-eeg-%C3%AE-power
#5
Heiko I Stecher, Tania M Pollok, Daniel Strüber, Fabian Sobotka, Christoph S Herrmann
Transcranial alternating current stimulation (tACS) sees increased use in neurosciences as a tool for the exploration of brain oscillations. It has been shown that tACS stimulation in specific frequency bands can result in aftereffects of modulated oscillatory brain activity that persist after the stimulation has ended. The general relationship between persistency of the effect and duration of stimulation is sparsely investigated but previous research has shown that the occurrence of tACS aftereffects depends on the brain state before and during stimulation...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28562642/enhancement-of-multitasking-performance-and-neural-oscillations-by-transcranial-alternating-current-stimulation
#6
Wan-Yu Hsu, Theodore P Zanto, Martine R van Schouwenburg, Adam Gazzaley
Multitasking is associated with the generation of stimulus-locked theta (4-7 Hz) oscillations arising from prefrontal cortex (PFC). Transcranial alternating current stimulation (tACS) is a non-invasive brain stimulation technique that influences endogenous brain oscillations. Here, we investigate whether applying alternating current stimulation within the theta frequency band would affect multitasking performance, and explore tACS effects on neurophysiological measures. Brief runs of bilateral PFC theta-tACS were applied while participants were engaged in a multitasking paradigm accompanied by electroencephalography (EEG) data collection...
2017: PloS One
https://www.readbyqxmd.com/read/28559805/semantic-feature-training-in-combination-with-transcranial-direct-current-stimulation-tdcs-for-progressive-anomia
#7
Jinyi Hung, Ashley Bauer, Murray Grossman, Roy H Hamilton, H B Coslett, Jamie Reilly
We examined the effectiveness of a 2-week regimen of a semantic feature training in combination with transcranial direct current stimulation (tDCS) for progressive naming impairment associated with primary progressive aphasia (N = 4) or early onset Alzheimer's Disease (N = 1). Patients received a 2-week regimen (10 sessions) of anodal tDCS delivered over the left temporoparietal cortex while completing a language therapy that consisted of repeated naming and semantic feature generation. Therapy targets consisted of familiar people, household items, clothes, foods, places, hygiene implements, and activities...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28533762/transcranial-alternating-current-stimulation-a-potential-modulator-for-pathological-oscillations-in-parkinson-s-disease
#8
Wei-Peng Teo, Ashlee M Hendy, Alicia M Goodwill, Andrea M Loftus
No abstract text is available yet for this article.
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28530336/-noninvasive-brain-stimulation-in-neuropsychiatric-disorders
#9
REVIEW
Doron Todder, Nimrod Grisaru, Zeev Kaplan
Noninvasive brain stimulation is a growing field of treatment for many neuropsychiatric problems. In this review, several of the more common brain stimulation devices are presented. Specifically, we will review Transcranial Magnetic Stimulation (TMS), Transcranial Direct Current Stimulation (tDCS), Alternating Current Stimulation (ACS), Infrared Stimulation, Electroencephalography Neurofeedback (EEG-NF) and functional Magnetic Resonance Imagining Neurofeedback (fMRI-NF). We will outline some of the properties of these devices including the mechanism, side effect profile, using sham for research and major future developments...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28528736/on-the-effectiveness-of-event-related-beta-tacs-on-episodic-memory-formation-and-motor-cortex-excitability
#10
Verena Braun, Rodika Sokoliuk, Simon Hanslmayr
BACKGROUND: Transcranial alternating current stimulation (tACS) is widely used to entrain or modulate brain oscillations in order to investigate causal relationships between oscillations and cognition. OBJECTIVE: In a series of experiments we here addressed the question of whether event-related, transient tACS in the beta frequency range can be used to entrain beta oscillations in two different domains: episodic memory formation and motor cortex excitability. METHODS: In experiments 1 and 2, 72 healthy human participants engaged in an incidental encoding task of verbal and non-verbal material while receiving tACS to the left and right inferior frontal gyrus (IFG) at 6...
April 30, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28469001/cerebellar-patients-do-not-benefit-from-cerebellar-or-m1-transcranial-direct-current-stimulation-during-force-field-reaching-adaptation
#11
Thomas Hulst, Liane John, Michael Küper, Jos N van der Geest, Sophia L Göricke, Opher Donchin, Dagmar Timmann
Several studies have identified transcranial direct current stimulation (tDCS) as a potential tool in the rehabilitation of cerebellar disease. Here, we tested whether tDCS could alleviate motor impairments of subjects with cerebellar degeneration. Three groups took part in this study: twenty individuals with cerebellar degeneration, twenty age-matched controls and thirty young controls. A standard reaching task with force field-perturbations was used to compare motor adaptation between groups and to measure the effect of stimulation of the cerebellum or primary motor cortex (M1)...
May 3, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28456902/cerebellar-transcranial-direct-current-stimulation-ctdcs-impairs-balance-control-in-healthy-individuals
#12
Águida Foerster, Lorena Melo, Marina Mello, Rebeca Castro, Lívia Shirahige, Sérgio Rocha, Kátia Monte-Silva
The cerebellum plays an important role in the planning, initiation and stability of movements, as well as in postural control and balance. Modulation of neural regions underlying balance control may be a potential alternative to treat balance impairments in cerebellar patients. Transcranial direct current stimulation (tDCS) is a noninvasive and safe tool capable to modulate cerebellar activity. We aim to investigate the effects of cerebellar tDCS (ctDCS) on postural balance in healthy individuals. Fifteen healthy and right-handed subjects were submitted to three sessions of ctDCS (anodal, cathodal and sham), separated by at least 48 h...
April 29, 2017: Cerebellum
https://www.readbyqxmd.com/read/28456901/what-do-we-know-about-the-influence-of-the-cerebellum-on-walking-ability-promising-findings-from-transcranial-alternating-current-stimulation
#13
Antonino Naro, Demetrio Milardi, Alberto Cacciola, Margherita Russo, Francesca Sciarrone, Gianluca La Rosa, Alessia Bramanti, Placido Bramanti, Rocco Salvatore Calabrò
Several cerebellar functions related to upper limb motor control have been studied using non-invasive brain stimulation paradigms. We have recently shown that transcranial alternating current stimulation (tACS) may be a promising approach in shaping the plasticity of cerebellum-brain pathways in a safe and effective manner. This study aimed to assess whether cerebellar tACS at different frequencies may tune M1-leg excitability and modify gait control in healthy human subjects. To this end, we tested the effects of different cerebellar tACS frequencies over the right cerebellar hemisphere (at 10, 50, and 300 Hz, besides a sham-tACS) on M1-leg excitability, cerebellum-brain inhibition (CBI), and gait parameters in a sample of 25 healthy volunteers...
April 29, 2017: Cerebellum
https://www.readbyqxmd.com/read/28385876/concurrent-tacs-fmri-reveals-causal-influence-of-power-synchronized-neural-activity-on-resting-state-fmri-connectivity
#14
Marc Bächinger, Valerio Zerbi, Marius Moisa, Rafael Polania, Quanying Liu, Dante Mantini, Christian Ruff, Nicole Wenderoth
Resting state fMRI (rs-fMRI) is commonly used to study the brain's intrinsic neural coupling, which reveals specific spatiotemporal patterns in the form of resting state networks (RSNs). It has been hypothesized that slow rs-fMRI oscillations (<0.1 Hz) are driven by underlying electrophysiological rhythms that typically occur at much faster timescales (>5 Hz); however, causal evidence for this relationship is currently lacking. Here we measured rs-fMRI in humans while applying transcranial alternating current stimulation (tACS) to entrain brain rhythms in left and right sensorimotor cortices...
May 3, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28385634/phonological-facilitation-in-picture-naming-when-and-where-a-tdcs-study
#15
Alberto Pisoni, Milena Cerciello, Zaira Cattaneo, Costanza Papagno
Phonological facilitation (PF) refers to a reduction of naming latencies when a phonologically related word is presented concurrently with the target picture, as compared to the presentation of phonologically unrelated words. According to spread of activation models of word production, this effect arises after lexical selection, during phonetic encoding, and is due to the co-activation of the phonemes shared by the target word and the distracter. Conversely, semantic interference (SI) is characterized by longer naming latencies when semantically related distracters are concurrently presented with the target picture...
June 3, 2017: Neuroscience
https://www.readbyqxmd.com/read/28373927/non-invasive-brain-stimulation-for-essential-tremor
#16
REVIEW
Ludy C Shih, Alvaro Pascual-Leone
BACKGROUND: There is increasing interest in the use of non-invasive brain stimulation to characterize and potentially treat essential tremor (ET). Studies have used a variety of stimulation coils, paradigms, and target locations to make these observations. We reviewed the literature to compare prior studies and to evaluate the rationale and the methods used in these studies. METHODS: We performed a systematic literature search of the PubMed database using the terms "transcranial," "noninvasive," "brain stimulation," "transcranial magnetic stimulation (TMS)," "transcranial direct current stimulation (tDCS)," "transcranial alternating current stimulation (tACS)," and "essential tremor...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28371170/state-of-the-art-novel-applications-for-cortical-stimulation
#17
REVIEW
Dirk De Ridder, Sanjaya Perera, Sven Vanneste
OBJECTIVE: Electrical stimulation via implanted electrodes that overlie the cortex of the brain is an upcoming neurosurgical technique that was hindered for a long time by insufficient knowledge of how the brain functions in a dynamic, physiological, and pathological way, as well as by technological limitations of the implantable stimulation devices. METHODS: This paper provides an overview of cortex stimulation via implantable devices and introduces future possibilities to improve cortex stimulation...
April 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28348136/driving-human-motor-cortical-oscillations-leads-to-behaviorally-relevant-changes-in-local-gabaa-inhibition-a-tacs-tms-study
#18
Magdalena Nowak, Emily Hinson, Freek van Ede, Alek Pogosyan, Andrea Guerra, Andrew Quinn, Peter Brown, Charlotte J Stagg
Beta and gamma oscillations are the dominant oscillatory activity in the human motor cortex (M1). However, their physiological basis and precise functional significance remain poorly understood. Here, we used transcranial magnetic stimulation (TMS) to examine the physiological basis and behavioral relevance of driving beta and gamma oscillatory activity in the human M1 using transcranial alternating current stimulation (tACS). tACS was applied using a sham-controlled crossover design at individualized intensity for 20 min and TMS was performed at rest (before, during, and after tACS) and during movement preparation (before and after tACS)...
April 26, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28323009/investigation-of-the-effects-of-transcranial-alternating-current-stimulation-tacs-on-self-paced-rhythmic-movements
#19
Manuel Varlet, Alanna Wade, Giacomo Novembre, Peter E Keller
Human rhythmic movements spontaneously entrain to external rhythmic stimuli. Such sensory-motor entrainment can attract movements to different tempi and enhance their efficiency, with potential clinical applications for motor rehabilitation. Here we investigate whether entrainment of self-paced rhythmic movements can be induced via transcranial alternating current stimulation (tACS), which uses alternating currents to entrain spontaneous brain oscillations at specific frequencies. Participants swung a handheld pendulum at their preferred tempo with the right hand while tACS was applied over their left or right primary motor cortex at frequencies equal to their preferred tempo (Experiment 1) or in the alpha (10Hz) and beta (20Hz) ranges (Experiment 2)...
March 18, 2017: Neuroscience
https://www.readbyqxmd.com/read/28322886/high-gamma-oscillations-in-the-motor-cortex-during-visuo-motor-coordination-a-tacs-interferential-study
#20
E Santarnecchi, A Biasella, E Tatti, A Rossi, D Prattichizzo, S Rossi
BACKGROUND: While the role of beta (∼20Hz), theta (∼5Hz) and alpha (∼10Hz) oscillations in the motor areas have been repeatedly associated with defined properties of motor performance, the investigation of gamma (∼40-90Hz) oscillatory activity is a more recent and still not fully understood component of motor control physiology, despite its potential clinical relevance for motor disorders. OBJECTIVE/HYPOTHESIS: We have implemented an online neuromodulation paradigm based on transcranial alternating current stimulation (tACS) of the dominant motor cortex during a visuo-motor coordination task...
March 18, 2017: Brain Research Bulletin
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