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R A Kardashian
AIM: To study personality characteristics in adolescents with computer game addiction. MATERIAL AND METHODS: The study included students of grades 7 to 10 at the age of 12-17 years (14.6±2.4 years), their parents and school teachers. RESULTS AND CONCLUSION: The results of a study showed the following combination in patients: 'genophilic' type of DPT with schizoid personality accentuation and 'projection' type of psychological protection, and 'dignitophilic' type of DPT with labile personality accentuation and 'denial' type of PP...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Polly J Bingley, Diane K Wherrett, Ann Shultz, Lisa E Rafkin, Mark A Atkinson, Carla J Greenbaum
What will it take to bring disease-modifying therapy to clinical use in type 1 diabetes? Coordinated efforts of investigators involved in discovery, translational, and clinical research operating in partnership with funders and industry and in sync with regulatory agencies are needed. This Perspective describes one such effort, Type 1 Diabetes TrialNet, a National Institutes of Health-funded and JDRF-supported international clinical trials network that emerged from the Diabetes Prevention Trial-Type 1 (DPT-1)...
April 2018: Diabetes Care
Ting Deng, Lei Wu, Jun-Min Gao, Bin Zhou, Ya-Li Zhang, Wen-Nan Wu, Zhuo-Heng Tang, Wen-Chao Jiang, Wei-Lin Huang
The occurrence and health risks of organotins (OTs) in the waterworks and source water in the Three Gorges Reservoir Region (TGRR), China were assessed in this study. Water samples were collected at four waterworks (A, B, C, and D) in March and July 2012 to analyze butyltins (BTs) and phenyltins (PTs) using a gas chromatography-mass spectrometry (GC-MS) system. Our results showed that both the waterworks and their nearby water sources were polluted by OTs, with PTs being the most dominant species. Monobutyltin (MBT), monophenyltin (MPT), diphenyltin (DPT), and triphenyltin (TPT) were detected in most of the analyzed water samples...
March 18, 2018: Environmental Science and Pollution Research International
(no author information available yet)
Cardiac rupture caused by traffic accident: Cases report and a literature review DOI: 10.1177/0025817218759164 Medico-Legal Journal In this article, six co-authors were omitted in the initial OnlineFirst version. The online version has been updated to list all co-authors and affiliations as below. S Zerbo1 , E Ventura Spagnolo1 , S Salerno2 , G Lo Re2 , A Guajana1 , A Alongi1 and A Argo1 1 Dpt. For Health Promotion, Maternal and Child Care, University of Palermo, Section of Legal Medicine. Palermo - Italy2 Dpt of Radiology, University of Palermo...
January 1, 2018: Medico-legal Journal
Xiaojie Zang, Guangji Wang, Qinngyun Cai, Xiao Zheng, Jingwei Zhang, Qianying Chen, Baojin Wu, Xiong Zhu, Haiping Hao, Fang Zhou
Multi-drug resistance (MDR) is a common limitation for the clinical use of microtubule-targeting chemotherapeutic agents and it is the main factor for poor prognoses in cancer therapy. Here, we report on deoxypodophyllotoxin (DPT), a promising microtubule inhibitor in phase I, as a promising candidate to circumvent the obstacle. DPT remarkably suppressed the tumor growth in xenograft mice bearing either Paclitaxel (PTX)-sensitive MCF-7/S or acquired resistance MCF-7/Adr (MCF-7/A) cells. Also, DPT exhibited a similar accumulation in both tumors, while PTX displayed much a lower accumulation in the resistant tumors...
March 9, 2018: Drug Metabolism and Disposition: the Biological Fate of Chemicals
Abdul Momin Kazi, Murtaza Ali, Khurram Zubair, Hussain Kalimuddin, Abdul Nafey Kazi, Saleem Perwaiz Iqbal, Jean-Paul Collet, Syed Asad Ali
BACKGROUND: Improved routine immunization (RI) coverage is recommended as the priority public health strategy to decrease vaccine-preventable diseases and eradicate polio in Pakistan and worldwide. OBJECTIVE: The objective of this study was to ascertain whether customized, automated, one-way text messaging (short message service, SMS) reminders delivered to caregivers via mobile phones when a child is due for an RI visit can improve vaccination uptake and timelines in Pakistan...
March 7, 2018: JMIR Public Health and Surveillance
Timothy Powell-Jackson, Camilla Fabbri, Varun Dutt, Sarah Tougher, Kultar Singh
BACKGROUND: To assess the effect of health information on immunisation uptake in rural India, we conducted an individually randomised controlled trial of health information messages targeting the mothers of unvaccinated or incompletely vaccinated children through home visits in rural Uttar Pradesh, India. METHODS AND FINDINGS: The study tested a brief intervention that provided mothers face-to-face with information on the benefits of the tetanus vaccine. Participants were 722 mothers of children aged 0-36 months who had not received 3 doses of diphtheria-pertussis-tetanus (DPT) vaccine (DPT3)...
March 2018: PLoS Medicine
Karen E Furgal, Elizabeth S Norris, Sonia N Young, Harvey W Wallmann
Development of professional behaviors in Doctor of Physical Therapy (DPT) students is an important part of professional education. The American Physical Therapy Association (APTA) has developed the Professionalism in Physical Therapy Core Values Self-Assessment (PPTCV-SA) tool to increase awareness of personal values in practice. The PPTCV-SA has been used to measure growth in professionalism following a clinical or educational experience. There are few studies reporting psychometric properties of the PPTCV-SA...
2018: Journal of Allied Health
Timothy J Bloom
Objective. To determine whether there is a distinctive pattern of StrengthsQuest Signature Themes or leadership domains for Doctor of Pharmacy students compared to students in other health care professional programs. Methods. Students in Doctor of Pharmacy (PharmD), Master of Physician Assistant (PA), Doctor of Physical Therapy (DPT), and Doctor of Osteopathic Medicine (DO) programs at Campbell University completed the online Clifton StrengthsQuest assessment and received their Signature Themes. The frequency of individual themes and the leadership domains into which they are sorted by Gallup was analyzed for each program...
February 2018: American Journal of Pharmaceutical Education
Ayşe İriz, Mehmet Düzlü, Oğuz Köktürk, Yusuf Kemal Kemaloğlu, Fakih Cihat Eravcı, Işık Sibel Küükünal, Recep Karamert
Background/aim: Obstructive sleep apnea syndrome (OSAS) is a disease characterized by repeated hypoxia attacks during sleep. The effect of hypoxia on the central nervous system is a well-known entity. In this study we aimed to investigate the effect of OSAS on the central auditory system. Materials and methods: Twenty-one OSAS patients diagnosed by polysomnography (PSG) and 10 control subjects were included in the study. After a thorough otorhinolaryngology examination, all subjects underwent pure tone audiometry (250 to 8000 Hz frequency)...
February 23, 2018: Turkish Journal of Medical Sciences
Jean D Miles, William H Staples, Daniel J Lee
BACKGROUND AND PURPOSE: Home care physical therapists (PTs) are inconsistent regarding cognitive screening, possibly because screening tools were traditionally considered the domain of other home care disciplines, or because therapists perceive their dementia training to be inadequate. A cross sectional study was designed to survey home care therapists' attitudes and beliefs about the management of persons with dementia and to find out whether any specific cognitive tools or measures are currently used...
February 14, 2018: Journal of Geriatric Physical Therapy
Shubhamoy Ghosh, Taraknath Ghosh, Ramkumar Mondal, Supratim Patra, Sumantra Das, Sk Swaif Ali, Munmun Koley, Subhranil Saha
BACKGROUND: Among the post-immunization adverse events, especially of Diphtheria-Pertusis-Tetanus (DPT), fever is a common systemic reaction. There is anecdotal support for the use of the homeopathic medicine Arsenicum album in preventing post-vaccination fever. The investigators intended to evaluate its efficacy in preventing febrile episodes following vaccination. METHODS: In the community medicine out-patient of Mahesh Bhattacharyya Homoeopathic Medical College and Hospital, West Bengal, India, between August 2014 and January 2017, a double-blind, randomized, placebo-controlled trial was conducted on 120 children (verum: 60, placebo: 60) who presented for the 2nd and 3rd dose of DPT-HepB-Polio vaccination and reported febrile episodes following the 1st dose...
February 2018: Complementary Therapies in Medicine
Roxane Labrosse, Louis Paradis, Jonathan Lacombe, Kathryn Samaan, François Graham, Jean Paradis, Philipps Bégin, Anne Des Roches
BACKGROUND: Penicillin allergy is the most frequent drug allergy, among which aminopenicillins are reputed for causing delayed rashes in children, particularly in the context of viral infections. Despite a negative allergy evaluation, a significant proportion of individuals continue to avoid penicillin antibiotics for fear of an allergic reaction. OBJECTIVE: To evaluate the safety and efficacy of a 5-day challenge to amoxicillin and the proportion of subsequent use of amoxicillin...
February 7, 2018: Journal of Allergy and Clinical Immunology in Practice
Rakesh Parida, Santanab Giri
Strength of acid can be determined by means of pKa value. Attempts have been made to find a relationship between pKa and activation energy barrier for a double proton transfer (DPT) reaction in inorganic acid dimers. Negative influence of pKa is observed on activation energy (Ea ) which is contrary to the general convention of pKa . Four different levels of theories with two different basis sets have been used to calculate the activation energy barrier of the DPT reaction in inorganic acid dimers. A model based on first and second order polynomial has been created to find the relationship between activation energy for DPT reaction...
February 8, 2018: Journal of Computational Chemistry
Ravi Prakash Upadhyay, Ranadip Chowdhury, Sarmila Mazumder, Sunita Taneja, Bireshwar Sinha, Jose Martines, Rajiv Bahl, Nita Bhandari, Maharaj Kishan Bhan
Background: Low birth weight (LBW) infants constitute a vulnerable subset of infants with impaired immunity in early life. In India, there is scarcity of studies that focus on immunization practices in such infants. This analysis aimed to examine immunization practices in LBW infants with the intention to identify areas requiring intervention. Methods: Data on immunization status of LBW infants enrolled in an individually randomized, double-masked, placebo-controlled trial of neonatal vitamin A supplementation were analysed...
December 2017: Journal of Global Health
Magdalena Sadyś, Joanna Kaczmarek, Agnieszka Grinn-Gofron, Victoria Rodinkova, Alex Prikhodko, Elena Bilous, Agnieszka Strzelczak, Robert J Herbert, Malgorzata Jedryczka
The genus Leptosphaeria contains numerous fungi that cause the symptoms of asthma and also parasitize wild and crop plants. In search of a robust and universal forecast model, the ascospore concentration in air was measured and weather data recorded from 1 March to 31 October between 2006 and 2012. The experiment was conducted in three European countries of the temperate climate, i.e., Ukraine, Poland, and the UK. Out of over 150 forecast models produced using artificial neural networks (ANNs) and multivariate regression trees (MRTs), we selected the best model for each site, as well as for joint two-site combinations...
January 27, 2018: International Journal of Biometeorology
Philip H Li, Annette Wagner, Iason Thomas, Timothy J Watts, Ryszard Rutkowski, Krzysztof Rutkowski
BACKGROUND: True corticosteroid (CS) allergy is rare. Instead, many patients may be allergic to excipients found in various CS preparations. Excipient testing is frequently overlooked. It might lead to unnecessary CS avoidance or dangerous re-exposure. OBJECTIVE: To evaluate the clinical characteristics and frequency of excipient allergy in patients with confirmed type I hypersensitivity to systemic CS preparations. METHODS: Patients with a confirmed diagnosis of allergy (positive skin test or drug provocation test (DPT)) or tolerance (negative DPT to CS) over the past 10 years were studied...
January 30, 2018: Journal of Allergy and Clinical Immunology in Practice
Assemien Boa, Alfred Douba, Tah Bi N Guessan, Hervé Menan, Alain Attia, Thimothée Ouassa, Joseph Bi Vroh Bénié, Armand Abokon, Mireille Dosso, Paul Aholi, Marguerite Timité-Konan, Raphaël Yao Abauleth, Emmanuel Bissagnéné, Joseph Aka, Jean Claude Yavo, Bonny Jean Sylvain, Germaine Siguifota Ouattara, Daniel Kouadio Ekra, Kadidia Sow, Jules N Guessan Kouassi, Eric Martial Kouakou Ahoussou, Raphaël Kalet Dally
The Côte d'Ivoire National Immunization Technical Advisory Group 2015 work plan included elaboration of an opinion on inclusion of hepatitis B vaccination at birth in the Expanded Program on Immunization (EPI) in Côte d'Ivoire. A task force was set up to conduct this assessment according to a systematized method. The task force analysed scientific articles on the burden of hepatitis B in Côte d'Ivoire, the burden of mother-child transmission, the impact of hepatitis B vaccination at birth in countries which have adopted this strategy, the efficacy and safety of hepatitis B vaccine in newborns, the cost-effectiveness of hepatitis B vaccination at birth, and the best strategy to introduce hepatitis B vaccination at birth in the EPI...
December 5, 2017: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
Silvia A Repetto, Paula Ruybal, Estela Batalla, Carlota López, Vanesa Fridman, Mariela Sierra, Marcelo Radisic, Pablo M Bravo, Marikena G Risso, Stella M González Cappa, Catalina D Alba Soto
Background: Strongyloides stercoralis affects 30-100 million people worldwide. The first-line therapy is ivermectin. Cure is defined as the absence of larvae by parasitological methods 1 year after treatment. To date, no longitudinal parasitological studies for longer periods of time have been conducted to confirm its cure. Here, we evaluated treatment response in long-term follow-up patients with chronic infection using parasitological and molecular methods for larvae or DNA detection...
January 19, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Vicente Plaza, Jordi Giner, Gustavo J Rodrigo, Myrna B Dolovich, Joaquin Sanchis
BACKGROUND: Inefficient inhaler technique (IT) compromises the optimal delivery of medication. However, the IT knowledge of health care professionals (HCP) has received scant attention. OBJECTIVE: To perform a systematic review of published reports assessing the IT proficiency of HCPs in using pressurized metered dose (pMDI) and dry powder (DPI) inhalers. METHODS: Studies published between 1975 and 2014 that directly assessed the IT skills of HCPs were selected according to pre-defined selection criteria...
January 17, 2018: Journal of Allergy and Clinical Immunology in Practice
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