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https://www.readbyqxmd.com/read/28924923/plant-insects-and-mites-uptake-double-stranded-rna-upon-its-exogenous-application-on-tomato-leaves
#1
Anupam Gogoi, Nomi Sarmah, Athanasios Kaldis, Dionysios Perdikis, Andreas Voloudakis
Exogenously applied double-stranded RNA (dsRNA) molecules onto tomato leaves, moved rapidly from local to systemic leaves and were uptaken by agricultural pests namely aphids, whiteflies and mites. Four small interfering RNAs, deriving from the applied dsRNA, were molecularly detected in plants, aphids and mites but not in whiteflies. Double-stranded RNA (dsRNA) acts as the elicitor molecule of the RNA silencing (RNA interference, RNAi), the endogenous and evolutionary conserved surveillance system present in all eukaryotes...
September 18, 2017: Planta
https://www.readbyqxmd.com/read/28923488/diagnostic-value-of-oral-challenge-testing-in-the-diagnosis-of-macrolide-hypersensitivity
#2
Derya Ünal, Semra Demir, Aslı Gelincik, Müge Olgaç, Raif Coşkun, Bahattin Çolakoğlu, Suna Büyüköztürk
BACKGROUND: Hypersensitivity reactions (HRs) to macrolides are rare. OBJECTIVE: The aim of this study was to evaluate the diagnostic value of in vivo tests in the diagnosis of HRs to macrolides and also to assess cross-reactivity between 4 different macrolides (clarithromycin, dirithromycin, spiramycin, and azithromycin) belonging to 3 different groups. METHODS: Twenty-five patients with a history of immediate or delayed-type HRs to at least 1 macrolide and 20 healthy control subjects underwent skin testing for both the culprit and alternative macrolides...
September 8, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28917263/fourier-transform-infrared-ftir-spectrophotometry-an-ecofriendly-method-for-the-analysis-of-injectable-daptomycin
#3
Eliane Gandolpho Tótoli, Hérida Regina Nunes Salgado
Daptomycin (DPT) is an important antimicrobial agent used in clinical practice because it is very active against several types of medicinally challenging Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci. In addition to concerns about the quality of the analytical methods used in the QC of drugs, there is also concern about the impact of these methods on the environment. The trend toward sustainable consumption is increasingly evident and has forced the pharmaceutical industry to reduce the generation of toxic waste...
September 1, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28889166/clinical-performance-and-admission-variables-as-predictors-of-passage-of-the-national-physical-therapy-examination
#4
Kelly M Meiners, Douglas K Rush
Prior studies have explored variables that had predictive relationships with National Physical Therapy Examination (NPTE) score or NPTE failure. The purpose of this study was to explore whether certain variables were predictive of test-takers' first-time score on the NPTE. SUBJECTS: The population consisted of 134 students who graduated from the university's Professional DPT Program in 2012 to 2014. METHODS: This quantitative study used a retrospective design. Two separate data analyses were conducted...
2017: Journal of Allied Health
https://www.readbyqxmd.com/read/28889162/meaningful-functional-change-achieved-from-physical-therapy-provided-in-a-student-run-pro-bono-clinic
#5
Suzanne R O'Brien, Melissa Bulas, Alexander Metcalfe, Zachary Mix, Todd Richert, Richard Wagner
OBJECTIVE: This study investigated whether patients with chronic neurologic diagnoses who attended a student-run pro bono physical therapy (PT) clinic achieved the minimum detectable change (MDC) on functional measures and the factors associated with such change. METHODS: Retrospective chart review included 71 patients with a primary diagnosis of stroke, traumatic brain injury, or multiple sclerosis from 2010 to 2014. The sample was 45% female, with a mean age of 62 yrs (SD 12...
2017: Journal of Allied Health
https://www.readbyqxmd.com/read/28868034/correction-of-high-astigmatism-after-penetrating-keratoplasty-with-toric-multifocal-intraocular-lens-implantation
#6
Raffaele Nuzzi, Francesca Monteu
After penetrating keratoplasty (PK), high astigmatism is often induced, being frequently about 4-6 dpt. According to the entity and typology of astigmatism, different methods of correction can be used. Selective suture removal, relaxing incisions, wedge resections, compression sutures, photorefractive keratectomy, and laser-assisted in situ keratomileusis can reduce corneal astigmatism and ametropia, but meanwhile they can cause a reduction in the corneal integrity and cause an over- or undercorrection. In case of moderate-to-high regular astigmatisms, the authors propose a toric multifocal intraocular lens (IOL) implantation to preserve the corneal integrity (especially in PK after herpetic corneal leukoma keratitis)...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28859592/dr-abbott-leaves-jospt-to-focus-on-research-program
#7
(no author information available yet)
The Board of Directors of JOSPT(®), Inc, d/b/a Movement Science Media (MSM), has accepted the resignation of J. Haxby Abbott, PhD, DPT, FNZCP, as Editor-in-Chief (EIC) of the Journal of Orthopaedic & Sports Physical Therapy, effective December 31, 2017. Dr Abbott is leaving JOSPT to focus on his research program and to spend time with his young family. The Board expects to appoint an interim EIC and to begin a search for Dr Abbott's successor. J Orthop Sports Phys Ther 2017;47(9):587. doi:10.2519/jospt.2017...
September 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28844660/dermatopontin-in-bone-marrow-extracellular-matrix-regulates-adherence-but-is-dispensable-for-murine-hematopoietic-cell-maintenance
#8
Ashley C Kramer, Amanda L Blake, Mandy E Taisto, Michael J Lehrke, Beau R Webber, Troy C Lund
The hematopoietic marrow microenvironment is composed of multiple cell types embedded in an extracellular matrix (ECM). We have explored marrow ECM using mass spectrometry and found dermatopontin (DPT), a small non-collagenous ECM protein, to be present. We found that DPT cooperates with other ECM proteins to promote hematopoietic cell adherence in vitro on plastic as well as OP9 stromal cells. We generated constitutional DPT(-/-) mice that were viable and had no peripheral lympho-hematopoietic abnormalities...
September 12, 2017: Stem Cell Reports
https://www.readbyqxmd.com/read/28841456/resveratrol-improves-smooth-muscle-carcinogenesis-in-the-progression-of-chronic-prostatitis-via-the-downregulation-of-c-kit-scf-by-activating-sirt1
#9
Yi He, Huizhi Zeng, Yang Yu, Jiashu Zhang, Xingping Duan, Qi Liu, Bo Yang
PURPOSE: Bladder smooth muscle cell death accompanied by hyperplasia and hypertrophy, as induced by inflammation, is the primary cause for poor bladder function. There are emerging evidences on the role of chronic inflammation as a factor involved in carcinogenesis and progression. We aim to determine the bladder smooth muscle pathological changes and dysfunction in chronic prostatitis (CP), to investigate whether resveratrol can improve the urinary dysfunction and the role of c-kit/SCF pathway, that has been associated with the smooth muscle carcinogenesis...
August 22, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28835200/research-productivity-of-doctor-of-physical-therapy-faculty-promoted-in-the-southeastern-united-states
#10
Marissa A Littman, James W Sonne, Gerald V Smith
BACKGROUND: Little information exists on the research productivity of successfully promoted tenure-track Doctor of Physical Therapy (DPT) faculty. OBJECTIVE: To determine the research productivity that typically results in successful promotion. DESIGN: We collected publicly available curriculum vitae (CVs) from faculty currently in accredited DPT programs and who had been successfully promoted from an institution in the southeastern USA from 2000 through 2016...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28830759/phencyclidine-like-in%C3%A2-vivo-effects-of-methoxetamine-in-mice-and-rats
#11
Michael D Berquist, William S Hyatt, Jonathan Bauer-Erickson, Brenda M Gannon, Andrew P Norwood, William E Fantegrossi
Methoxetamine (MXE) is a novel drug of abuse that is structurally similar to phencyclidine (PCP). In the present study, rats were trained to discriminate PCP from saline and substitution tests were performed with arylcyclohexylamines PCP, eticyclidine (PCE), tenocyclidine (TCP), and MXE. PCP and PCE engendered PCP-lever selection in all subjects, whereas MXE and TCP produced PCP-lever selection in animals that did not display behavioral disruption. Last, the substituted tryptamine dipropyltryptamine (DPT) produced moderate PCP-lever selection and elicited behavioral disruption in all subjects at the highest dose tested...
August 19, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28808638/effect-of-surface-treatment-on-the-mechanical-properties-of-nickel-titanium-files-with-a-similar-cross-section
#12
Sang Won Kwak, Joo Yeong Lee, Hye-Jin Goo, Hyeon-Cheol Kim
OBJECTIVES: The aim of this study was to compare the mechanical properties of various nickel-titanium (NiTi) files with similar tapers and cross-sectional areas depending on whether they were surface-treated. MATERIALS AND METHODS: Three NiTi file systems with a similar convex triangular cross-section and the same ISO #25 tip size were selected for this study: G6 (G6), ProTaper Universal (PTU), and Dia-PT (DPT). To test torsional resistance, 5 mm of the straightened file's tip was fixed between polycarbonate blocks (n = 15/group) and continuous clockwise rotation until fracture was conducted using a customized device...
August 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28805672/challenges-in-estimating-vaccine-coverage-in-refugee-and-displaced-populations-results-from-household-surveys-in-jordan-and-lebanon
#13
Timothy Roberton, William Weiss, Shannon Doocy
Ensuring the sustained immunization of displaced persons is a key objective in humanitarian emergencies. Typically, humanitarian actors measure coverage of single vaccines following an immunization campaign; few measure routine coverage of all vaccines. We undertook household surveys of Syrian refugees in Jordan and Lebanon, outside of camps, using a mix of random and respondent-driven sampling, to measure coverage of all vaccinations included in the host country's vaccine schedule. We analyzed the results with a critical eye to data limitations and implications for similar studies...
August 12, 2017: Vaccines
https://www.readbyqxmd.com/read/28791483/influence-of-season-age-and-management-on-scrotal-thermal-profile-in-murrah-bulls-using-scrotal-infrared-digital-thermography
#14
Maneesh Kumar Ahirwar, Mukund Amritrao Kataktalware, Kerekoppa Puttaiah Ramesha, Heartwin Amaladhas Pushpadass, Sakthivel Jeyakumar, Deginal Revanasiddu, Reen Jagish Kour, Sapna Nath, Anand Kumar Nagaleekar, Sayyad Nazar
The aim of the present study was to examine the effects of non-genetic factors on scrotal thermographic profile viz., proximal pole temperature (PPT °C), mid pole temperature (MPT °C), distal pole temperature (DPT °C) and ocular temperature (OcT) of Murrah (Bubalus bubalis) breeding bulls. A total of 109 buffalo bulls, maintained at three semen stations (SS), were monitored for scrotal surface and ocular temperatures using infrared thermography twice daily during rainy, winter and summer seasons using an FLIR i5 infrared camera and temperatures were measured...
August 9, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28777557/double-solvent-sensing-method-for-improving-sensitivity-and-accuracy-of-hg-ii-detection-based-on-different-signal-transduction-of-a-tetrazine-functionalized-pillared-metal-organic-framework
#15
Sayed Ali Akbar Razavi, Mohammad Yaser Masoomi, Ali Morsali
To design a robust, π-conjugated, low-cost, and easy to synthesize metal-organic framework (MOF) for cation sensing by the photoluminescence (PL) method, 4,4'-oxybis(benzoic acid) (H2OBA) has been used in combination with 3,6-di(pyridin-4-yl)-1,2,4,5-tetrazine (DPT) as a tetrazine-functionalized spacer to construct [Zn(OBA)(DPT)0.5]·DMF (TMU-34(-2H)). The tetrazine motif is a π-conjugated, water-soluble/stable fluorophore with relatively weak σ-donating Lewis basic sites. These characteristics of tetrazine make TMU-34(-2H) a good candidate for cation sensing...
August 4, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28717889/combined-arthroscopically-assisted-coraco-and-acromioclavicular-stabilization-of-acute-high-grade-acromioclavicular-joint-separations
#16
Carmen Hann, Natascha Kraus, Marvin Minkus, Nina Maziak, Markus Scheibel
PURPOSE AND HYPOTHESIS: Due to high rate of persisting dynamic posterior translation (DPT) following isolated coracoclavicular double-button technique for reconstruction of the acromioclavicular (AC) joint reported in the literature, an additional acromioclavicular cerclage was added to the procedure. The aim of this study was to evaluate the clinical and radiological results of patients with high-grade AC-joint instability treated with a double TightRope technique with an additional percutaneous acromioclavicular cerclage...
July 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28707542/the-physiological-consequences-of-different-distributions-of-diffuse-pleural-thickening-on-ct-imaging
#17
Duneesha de Fonseka, Anthony Edey, Louise Stadon, Jason Viner, Michael Darby, Nick A Maskell
OBJECTIVE: Diffuse pleural thickening (DPT) refers to extensive visceral pleural fibrosis with adhesion formation to the parietal pleura obliterating the pleural space. The radiological definition of DPT remains controversial with most of the literature requiring the presence of an obliterated costophrenic angle (CPA) for defining DPT. We conducted a study to investigate the variable distributions of DPT and associated lung function deficit. METHODS: 85 patients referred to a pleural clinic with suspected pleural thickening were screened for our study...
August 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28704753/resveratrol-improves-prostate-fibrosis-during-progression-of-urinary-dysfunction-in-chronic-prostatitis
#18
Yi He, Hui-Zhi Zeng, Yang Yu, Jia-Shu Zhang, Xingping Duan, Xiao-Na Zeng, Feng-Tao Gong, Qi Liu, Bo Yang
AIM: We investigated whether prostate fibrosis was associated with urinary dysfunction in chronic prostatitis (CP) and whether resveratrol improved urinary dysfunction and the underlying molecular mechanism. METHODS: Rat model of CP was established via subcutaneous injections of DPT vaccine and subsequently treated with resveratrol. Bladder pressure and volume tests investigated the effect of resveratrol on urinary dysfunction in CP rats. Western blotting and immunohistochemical staining examined the expression level of C-kit/SCF and TGF-β/Wnt/β-catenin...
July 1, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28700047/influence-of-meteorological-variables-on-dengue-incidence-in-the-municipality-of-arapiraca-alagoas-brazil
#19
Washington Luiz Félix Correia
INTRODUCTION: Meteorological influences along with the lack of basic sanitation has contributed to disease outbreaks, resulting in large socio-economic losses, especially in terms of dengue. This study aimed to evaluate the meteorological influences on the monthly incidence of dengue in Arapiraca-AL, Brazil during 2008-2015. METHODS: We used generalized linear models constructed via logistic regression to assess the association between the monthly incidence of dengue (MID) of and 8 meteorological variables [rainfall (R), air temperature (AT), dew point temperature (DPT), relative humidity (RH), pressure surface, wind speed (WS), wind direction (WD), and gust], based on data obtained from DATASUS and meteorological station databases, respectively...
May 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28677662/pro-and-contra-provocation-tests-in-drug-hypersensitivity
#20
REVIEW
Ozge Soyer, Umit Murat Sahiner, Bulent Enis Sekerel
Drug provocation test (DPT) is the controlled administration of a drug to diagnose immune- or non-immune-mediated drug hypersensitivity and the last step for accurate recognition of drug hypersensitivity reactions when the previous diagnostic evaluations are negative or unavailable. A DPT is performed only if other conventional tests fail to yield conclusive results. In each clinical presentation, "to provoke or not to provoke" a patient should be decided after careful assessment of the risk-benefit ratio. Well-defined benefits of DPT include confirmative exclusion of diagnoses of drug hypersensitivity and provision of safe alternatives...
July 4, 2017: International Journal of Molecular Sciences
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