keyword
MENU ▼
Read by QxMD icon Read
search

inflammatory bowel disease dog

keyword
https://www.readbyqxmd.com/read/28905976/cutaneous-alternariosis-in-an-immunocompromised-dog-successfully-treated-with-cold-plasma-and-cessation-of-immunosuppressive-medication
#1
Janine Classen, Berrett Dengler, Christoph J Klinger, Sonya V Bettenay, Volker Rickerts, Ralf S Mueller
A cutaneous infection with Alternaria spp. was diagnosed in a 2-year-old male intact Irish setter dog, presenting with multifocal papules, plaques and ulcerations involving all four distal limbs, shoulder blades, scrotum, pinnae and nasal mucous membranes. The dog had been treated for inflammatory bowel disease and lymphangiectasia with immunosuppressive doses of cyclosporine and prednisolone for approximately 3 months. The diagnosis was based on clinical signs, the demonstration of fungal elements within skin biopsies, deep fungal culture and fungal PCR from a formalin-fixed tissue specimen...
September 13, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28900347/campylobacter-from-microbiology-to-prevention
#2
REVIEW
A Facciolà, R Riso, E Avventuroso, G Visalli, S A Delia, P Laganà
In last years, Campylobacter spp has become one of the most important foodborne pathogens even in high-income countries. Particularly, in Europe, Campylobacteriosis is, since 2005, the foodborne disease most frequently notified and the second in USA, preceded by the infection due to Salmonella spp. Campylobacter spp is a commensal microorganism of the gastrointestinal tract of many wild animals (birds such as ducks and gulls), farm animals (cattle and pigs) and companion animals (such as dogs and cats) and it is responsible for zoonoses...
June 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28862348/immunophenotype-of-peripheral-blood-lymphocytes-in-dogs-with-inflammatory-bowel-disease
#3
A Galler, B C Rütgen, E Haas, A Saalmüller, R A Hirt, W Gerner, I Schwendenwein, B Richter, J G Thalhammer, N Luckschander-Zeller
BACKGROUND: Inflammatory bowel disease (IBD) is common in dogs. Despite the known importance of intestinal lymphocytes in its pathogenesis, little is known about the role of peripheral blood lymphocytes (PBLs) in IBD. OBJECTIVES: The aims of this study were (1) comparison of PBLs analyzed by flow cytometry (FCM) in IBD dogs and healthy controls and (2) comparison of PBLs in IBD dogs at the time of diagnosis and in dogs in clinical remission. ANIMALS: Whole blood samples of 19 IBD dogs at the time of diagnosis and blood samples of 6 dogs in clinical remission were collected...
September 1, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28738011/associations-between-gastric-dilatation-volvulus-in-great-danes-and-specific-alleles-of-the-canine-immune-system-genes-dla88-drb1-and-tlr5
#4
Michael A Harkey, Alexandra M Villagran, Gopalakrishnan M Venkataraman, Wendy M Leisenring, Meredith A J Hullar, Beverly J Torok-Storb
OBJECTIVE To determine whether specific alleles of candidate genes of the major histocompatibility complex (MHC) and innate immune system were associated with gastric dilatation-volvulus (GDV) in Great Danes. ANIMALS 42 healthy Great Danes (control group) and 39 Great Danes with ≥ 1 GDV episode. PROCEDURES Variable regions of the 2 most polymorphic MHC genes (DLA88 and DRB1) were amplified and sequenced from the dogs in each group. Similarly, regions of 3 genes associated with the innate immune system (TLR5, NOD2, and ATG16L1), which have been linked to inflammatory bowel disease, were amplified and sequenced...
August 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28678609/randomized-controlled-trial-evaluating-the-effect-of-multi-strain-probiotic-on-the-mucosal-microbiota-in-canine-idiopathic-inflammatory-bowel-disease
#5
Robin White, Todd Atherly, Blake Guard, Giacomo Rossi, Chong Wang, Curtis Mosher, Craig Webb, Steve Hill, Mark Ackermann, Peter Sciabarra, Karin Allenspach, Jan Suchodolski, Albert E Jergens
The intestinal microbiota is increasingly linked to the pathogenesis of idiopathic inflammatory bowel disease (IBD) in dogs. While studies have reported alterations in fecal (luminal) microbial populations, only limited information is available about the mucosal microbiota of IBD dogs at diagnosis and following medical therapy. Our aim was to characterize the mucosal microbiota and determine the clinical, microbiological, and mucosal homeostatic effects of probiotic treatment in dogs with IBD. Thirty four IBD dogs were randomized to receive standard therapy (ST = diet + prednisone) with or without probiotic...
July 5, 2017: Gut Microbes
https://www.readbyqxmd.com/read/28408781/inflammatory-bowel-disease-affects-density-of-nitrergic-nerve-fibers-in-the-mucosal-layer-of-the-canine-gastrointestinal-tract
#6
Andrzej Rychlik, Slawomir Gonkowski, Marcin Nowicki, Jaroslaw Calka
The objective of this study was to determine the effect of inflammatory bowel disease (IBD) on the density of nitrergic nerve fibers in the mucosal layer of different sections of the gastrointestinal tract of dogs. Twenty-eight German shepherd hybrid dogs of both sexes, weighing from 15 to 25 kg and aged 6 to 10 y, were studied. The dogs were divided into 4 groups with 7 animals in each group: healthy animals, as well as dogs suffering from mild, moderate, and severe IBD. Immunoreactivity to neuronal isoform of nitric oxide synthase, which is a marker of nitrergic neurons, in samples of the mucosal layer in the duodenum, jejunum, and descending colon was studied using the single immunofluorescence method and the number of nerve fibers was evaluated in each observation field...
April 2017: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/28283081/serum-biomarkers-of-oxidative-stress-in-dogs-with-idiopathic-inflammatory-bowel-disease
#7
C P Rubio, S Martínez-Subiela, J Hernández-Ruiz, A Tvarijonaviciute, J J Cerón, K Allenspach
The objective of this work was to study and compare a panel of various serum biomarkers evaluating both the antioxidant response and oxidative damage in dogs with idiopathic inflammatory bowel disease (IBD). Eighteen dogs with IBD and 20 healthy dogs were enrolled in the study. Trolox equivalent antioxidant capacity (TEAC), cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of the plasma (FRAP), total thiol concentrations, and paraoxonase 1 (PON1) activity were evaluated in serum to determine antioxidant response...
March 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28282232/an-atypical-case-of-leishmaniasis-associated-with-chronic-duodenitis-in-a-dog
#8
Ignacio Ayala, Luis Jesus Bernal, Juan Diego Garcia-Martinez, Miguel Angel Gomez, Jose Antonio Navarro, Antonio Bernabe
We describe an atypical case of duodenal leishmaniasis in a boxer dog presenting with chronic diarrhea and poor general condition. Antidiarrheic therapy was previously administered without success and inflammatory bowel disease localized to the small intestine was suspected, given the chronic clinical signs and by ruling out other known causes of gastrointestinal inflammation. Endoscopic biopsy of duodenum showed a moderate increase in lamina propria lymphocytes, plasma cells, and macrophages. Basophilic bodies were seen in the cytoplasm of numerous macrophages, suggestive of Leishmania spp, confirmed by immunostaining, and a diagnosis of granulomatous duodenitis associated to Leishmania infection was made...
March 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28247992/a-retrospective-study-of-dogs-with-atypical-hypoadrenocorticism-a%C3%A2-diagnostic-cut-off-or-continuum
#9
J A Wakayama, E Furrow, L K Merkel, P J Armstrong
OBJECTIVES: To describe the clinicopathologic findings and outcome in dogs with atypical hypoadrenocorticism (Group 1) and dogs with suspected atypical hypoadrenocorticism whose post-adrenocorticotropic hormone stimulation cortisol concentrations were greater than 55 nmol/L but below the laboratory reference interval (Group 2). METHODS: Medical records were searched to identify dogs diagnosed with hypoadrenocorticism between January 2004 and June 2014. Dogs were excluded if their Na:K ratio was less than 27 or if they had received prior therapy that could interfere with adrenocorticotropic hormone stimulation testing...
July 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28089357/localization-of-toll-like-receptor-tlr-2-and-tlr4-mrna-in-the-colorectal-mucosa-of-miniature-dachshunds-with-inflammatory-colorectal-polyps
#10
N Yokoyama, H Ohta, J Yamazaki, Y Kagawa, O Ichii, N Khoirun, T Morita, T Osuga, S Y Lim, N Sasaki, K Morishita, K Nakamura, M Takiguchi
Inflammatory colorectal polyps (ICRPs) are characterized by the formation of multiple or solitary polyps with marked neutrophil infiltration in the colorectal area, and are speculated to be a novel form of breed-specific canine idiopathic inflammatory bowel disease (IBD). In human IBD, toll-like receptor (TLR) 2 and TLR4 have been reported to be involved in the pathogenesis of the disease. The aim of this study was to evaluate the expression of TLR2 and TLR4 mRNA in the colorectal mucosa of dogs with ICRPs by in-situ hybridization using an RNAscope assay...
February 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28049868/expression-of-epithelial-cell-derived-cytokine-genes-in-the-duodenal-and-colonic-mucosae-of-dogs-with-chronic-enteropathy
#11
Hironari Osada, Misato Ogawa, Ayana Hasegawa, Makoto Nagai, Junsuke Shirai, Kazuaki Sasaki, Minoru Shimoda, Hiroshi Itoh, Hirotaka Kondo, Keitaro Ohmori
It remains unclear whether epithelial cell-derived cytokines, including interleukin (IL)-25, IL-33 and thymic stromal lymphopoietin (TSLP), contribute to development of canine chronic enteropathy (CE), which includes antibiotic-responsive enteropathy (ARE), food-responsive enteropathy (FRE) and inflammatory bowel disease (IBD). In the present study, we examined mRNA expression of il-25, il-33 and tslp in the duodenal and colonic mucosae of dogs with ARE, FRE and IBD. Real-time PCR analysis revealed that mRNA expression of il-33 was significantly lower in the duodenum in dogs with FRE than in healthy dogs...
February 28, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28029282/assessment-of-eosinophil-peroxidase-as-a-potential-diagnostic-and-prognostic-marker-in-dogs-with-inflammatory-bowel-disease
#12
Idil Bastan, Nicholas A Robinson, Xiao Na Ge, Aaron K Rendahl, Savita P Rao, Robert J Washabau, P Sriramarao
OBJECTIVE To evaluate a method for identifying intact and degranulated eosinophils in the small intestine of dogs with inflammatory bowel disease (IBD) by use of a monoclonal antibody (mAb) against eosinophil peroxidase (EPX). ANIMALS 11 untreated dogs with IBD, 5 dogs with IBD treated with prednisolone, and 8 control dogs with no clinical evidence of gastrointestinal tract disease and no immunosuppressive treatment. PROCEDURES 4-μm-thick sections of paraffin-embedded tissues from necropsy specimens were immunostained with EPX mAb...
January 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27941060/effects-of-a-structured-exercise-programme-in-sedentary-dogs-with-chronic-diarrhoea
#13
RANDOMIZED CONTROLLED TRIAL
H-P Huang, Y-H Lien
The aim of this investigation was to evaluate the effects of a structured exercise programme in sedentary dogs with chronic diarrhoea. Twenty-two dogs were enrolled in the study. All dogs received oral prednisolone (1 mg/kg/day for 14 days, followed by a tapering dosage) for 10 weeks. After four weeks of prednisolone treatment, dogs were assigned to either the exercise or control group (n=11 each). Owners of dogs in the exercise group were instructed to guide their dogs in structured exercise training (low-intensity to moderate-intensity aerobic and resistance exercise three to five days per week)...
March 4, 2017: Veterinary Record
https://www.readbyqxmd.com/read/27931211/gonadectomy-effects-on-the-risk-of-immune-disorders-in-the-dog-a-retrospective-study
#14
Crystal R Sundburg, Janelle M Belanger, Danika L Bannasch, Thomas R Famula, Anita M Oberbauer
BACKGROUND: Gonadectomy is one of the most common procedures performed on dogs in the United States. Neutering has been shown to reduce the risk for some diseases although recent reports suggest increased prevalence for structural disorders and some neoplasias. The relation between neuter status and autoimmune diseases has not been explored. This study evaluated the prevalence and risk of atopic dermatitis (ATOP), autoimmune hemolytic anemia (AIHA), canine myasthenia gravis (CMG), colitis (COL), hypoadrenocorticism (ADD), hypothyroidism (HYPO), immune-mediated polyarthritis (IMPA), immune-mediated thrombocytopenia (ITP), inflammatory bowel disease (IBD), lupus erythematosus (LUP), and pemphigus complex (PEMC), for intact females, intact males, neutered females, and neutered males...
December 8, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27863539/single-nucleotide-polymorphisms-in-major-histocompatibility-class-ii-haplotypes-are-associated-with-potential-resistance-to-inflammatory-bowel-disease-in-german-shepherd-dogs
#15
Atiyeh Peiravan, Karin Allenspach, Alisdair M Boag, Francesca Soutter, Angela Holder, Brian Catchpole, Lorna J Kennedy, Dirk Werling, Fabio Procoli
German shepherd dogs (GSD) in the UK are at increased risk of developing the Inflammatory Bowel Disaese (IBD). IBD is believed to be a multifactorial immune mediated disease affecting genetically predisposed dogs. The aim of the current study was to investigate whether susceptibility to IBD in GSD is associated with the major histocompatibility complex (MHC) class II locus (Dog Leukocyte Antigen, DLA). Sequence-based genotyping of the three polymorphic DLA genes DLA-DRB1, -DQA1 and -DQB1 was performed in 56 GSDs affected by IBD and in 50 breed-matched controls without any history of gastrointestinal signs...
December 2016: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/27747868/inflammatory-bowel-disease-versus-chronic-enteropathy-in-dogs-are-they-one-and-the-same
#16
REVIEW
J R S Dandrieux
The aim of this review is to discuss why "chronic enteropathy" might be a better term than "inflammatory bowel disease" in dogs, because the treatment and outcome of the disease is very different from that of inflammatory bowel disease in humans. The effect of food, antibiotics and immunosuppressant drugs on chronic enteropathy will be reviewed. New treatments under investigation will also be introduced. Although there are several studies evaluating treatment of chronic enteropathy in dogs, the quality and quantity of evidence supporting individual therapies remains scarce and more work is needed to improve management of this disease...
November 2016: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/27698166/validation-of-three-automated-assays-for-total-antioxidant-capacity-determination-in-canine-serum-samples
#17
Camila Peres Rubio, Josefa Hernández-Ruiz, Silvia Martinez-Subiela, Asta Tvarijonaviciute, Marino Bañón Arnao, José Joaquín Ceron
We performed analytical validation of 3 automated assays of the total antioxidant capacity (TAC) in canine serum and evaluated their use in dogs with inflammatory bowel disease. The assays were based on the generation of a 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radical cation (ABTS•(+)) in aqueous media, which produces a blue-green color. The antioxidants present in the sample remove the chromogen in proportion to their concentrations. The assays differed mainly in the way in which this radical was produced...
November 2016: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/27694806/dog-and-human-inflammatory-bowel-disease-rely-on-overlapping-yet-distinct-dysbiosis-networks
#18
Yoshiki Vázquez-Baeza, Embriette R Hyde, Jan S Suchodolski, Rob Knight
Inflammatory bowel disease (IBD) is an autoimmune condition that is difficult to diagnose, and animal models of this disease have questionable human relevance(1). Here, we show that the dysbiosis network underlying IBD in dogs differs from that in humans, with some bacteria such as Fusobacterium switching roles between the two species (as Bacteroides fragilis switches roles between humans and mice)(2). For example, a dysbiosis index trained on humans fails when applied to dogs, but a dog-specific dysbiosis index achieves high correlations with the overall dog microbial community diversity patterns...
October 3, 2016: Nature Microbiology
https://www.readbyqxmd.com/read/27538863/serum-cobalamin-vitamin-b12-concentrations-in-rhesus-macaques-macaca-mulatta-and-pigtailed-macaques-macaca-nemestrina-with-chronic-idiopathic-diarrhea
#19
Jessica M Izzi, Sarah E Beck, Robert J Adams, Kelly A Metcalf Pate, Eric K Hutchinson
Chronic diarrhea poses a significant threat to the health of NHP research colonies, and its primary etiology remains unclear. In macaques, the clinical presentation of intractable diarrhea and weight loss that are accompanied by inflammatory infiltrates within the gastrointestinal tract closely resembles inflammatory bowel disease of humans, dogs, and cats, in which low serum and tissue cobalamin (vitamin B12) levels are due to intestinal malabsorption. We therefore hypothesized that macaques with chronic idiopathic diarrhea (CID) have lower serum cobalamin concentrations than do healthy macaques...
2016: Comparative Medicine
https://www.readbyqxmd.com/read/27408833/an-lc-ms-ms-method-for-the-determination-of-budesonide-and-16%C3%AE-hydroxyprednisolone-in-dog-plasma
#20
Teresa Gazzotti, Andrea Barbarossa, Elisa Zironi, Paola Roncada, Marco Pietra, Giampiero Pagliuca
Although budesonide is frequently used in veterinary medicine for the treatment of canine respiratory and bowel inflammatory diseases, knowledge is lacking regarding its kinetics in this species. We developed and validated a liquid chromatography-tandem mass spectrometry method for the determination of budesonide and its metabolite 16α-hydroxyprednisolone in dog plasma. The analytes were extracted by solid phase extraction and analysis was performed by high performance liquid chromatography-tandem mass spectrometry, with positive electrospray ionization...
2016: MethodsX
keyword
keyword
47526
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"