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Climacteric

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https://www.readbyqxmd.com/read/29028545/penicillium-expansum-compatible-and-penicillium-digitatum-non-host-pathogen-infection-differentially-alter-ethylene-biosynthesis-in-apple-fruit
#1
Laura Vilanova, Núria Vall-Llaura, Rosario Torres, Josep Usall, Neus Teixidó, Christian Larrigaudière, Jordi Giné-Bordonaba
The role of ethylene on inducing plant resistance or susceptibility to certain fungal pathogens clearly depends on the plant pathogen interaction with little or no-information available focused on the apple-Penicillium interaction. Taken advantage that Penicillium expansum is the compatible pathogen and P. digitatum is the non-host of apples, the present study aimed at deciphering how each Penicillium spp. could interfere in the fruit ethylene biosynthesis at the biochemical and molecular level. The infection capacity and different aspects related to the ethylene biosynthesis were conducted at different times post-inoculation...
September 30, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28970109/metabolic-profiling-of-garcinia-mangostana-mangosteen-based-on-ripening-stages
#2
Anjaritha A R Parijadi, Sastia P Putri, Sobir Ridwani, Fenny M Dwivany, Eiichiro Fukusaki
Metabolomics is an emerging research field based on exhaustive metabolite profiling that have been proven useful to facilitate the study of postharvest fruit development and ripening. Specifically, tracking changes to the metabolome as fruit ripens should provide important clues for understanding ripening mechanisms and identify bio-markers to improve post-harvest technology of fruits. This study conducted a time-course metabolome analysis in mangosteen, an economically important tropical fruit valued for its flavor...
September 29, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28966632/effects-of-estrogen-receptor-modulators-on-cytoskeletal-proteins-in-the-central-nervous-system
#3
REVIEW
Julia J Segura-Uribe, Rodolfo Pinto-Almazán, Angélica Coyoy-Salgado, Claudia E Fuentes-Venado, Christian Guerra-Araiza
Estrogen receptor modulators are compounds of interest because of their estrogenic agonistic/antagonistic effects and tissue specificity. These compounds have many clinical applications, particularly for breast cancer treatment and osteoporosis in postmenopausal women, as well as for the treatment of climacteric symptoms. Similar to estrogens, neuroprotective effects of estrogen receptor modulators have been described in different models. However, the mechanisms of action of these compounds in the central nervous system have not been fully described...
August 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28955353/a-transcriptome-approach-toward-understanding-fruit-softening-in-persimmon
#4
Jihye Jung, Sang Chul Choi, Sunghee Jung, Byung-Kwan Cho, Gwang-Hwan Ahn, Stephen B Ryu
Persimmon (Diospyros kaki Thunb.), which is a climacteric fruit, softens in 3-5 weeks after harvest. However, little is known regarding the transcriptional changes that underlie persimmon ripening. In this study, high-throughput de novo RNA sequencing was performed to examine differential expression between freshly harvested (FH) and softened (ST) persimmon fruit peels. Using the Illumina HiSeq platform, we obtained 259,483,704 high quality reads and 94,856 transcripts. After the removal of redundant sequences, a total of 31,258 unigenes were predicted, 1,790 of which were differentially expressed between FH and ST persimmon (1,284 up-regulated and 506 down-regulated in ST compared with FH)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28933968/influence-of-menopausal-symptoms-on-perceived-work-ability-among-women-in-a-nigerian-university
#5
A O Olajubu, A E Olowokere, D O Amujo, T O Olajubu
OBJECTIVES: This study investigated the menopausal symptoms experienced by women of menopausal age in Ekiti State, Nigeria and the influence on their perceived work ability. METHOD: A descriptive cross-sectional research design was employed and the study was conducted among 200 working-class women aged 45 years and above who had experienced at least 12 continuous months of amenorrhea in Ekiti State University, Ado Ekiti. A semi-structured questionnaire adapted from the Greene Climacteric Scale and the work ability index was used to assess menopausal symptoms and work ability, respectively...
September 21, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28932910/a-histone-deacetylase-gene-slhda3-acts-as-a-negative-regulator-of-fruit-ripening-and-carotenoid-accumulation
#6
Jun-E Guo, Zongli Hu, Xiaohui Yu, Anzhou Li, Fenfen Li, Yunshu Wang, Shibing Tian, Guoping Chen
SlHDA3 functions as an inhibitor and regulates tomato fruit ripening and carotenoid accumulation. Post-translational modifications, including histones acetylation, play a pivotal role in the changes of chromatin structure dynamic modulation and gene activity. The regulation of histone acetylation is achieved by the action of histone acetyltransferases and deacetylases, which play crucial roles in the regulation of transcription activation. There is an increasing research focus on histone deacetylation in crops, but the role of histone deacetylase genes (HDACs) in tomato has not been elucidated...
September 20, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28931356/menopause-a-complex-and-controversial-journey
#7
Salam Chalouhi
Menopause is defined as permanent cessation of menstrual periods, determined retrospectively after a woman has experienced 12 months of amenorrhea without any other obvious cause. Over the years, the discourse surrounding the Climacteric was mainly elicited as a "disease of the castrates", as opposed to the feminist views. There has been a large feminist contribution to both the debate of contraception and menopause in the last few years. Over the years, menopause has been treated in a uniform fashion, as a disease, excluding the different circumstances and lived experiences that patients go through during this sensitive period...
September 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28928762/novel-protein-protein-inhibitor-based-approach-to-control-plant-ethylene-responses-synthetic-peptides-for-ripening-control
#8
Mareike Kessenbrock, Simone M Klein, Lena Müller, Mauricio Hunsche, Georg Noga, Georg Groth
Ethylene signaling is decisive for many plant developmental processes. Among these, control of senescence, abscission and fruit ripening are of fundamental relevance for global agriculture. Consequently, detailed knowledge of the signaling network along with the molecular processes of signal perception and transfer are expected to have high impact on future food production and agriculture. Recent advances in ethylene research have demonstrated that signaling of the plant hormone critically depends on the interaction of the ethylene receptor family with the NRAMP-like membrane protein ETHYLENE INSENSITIVE 2 (EIN2) at the ER membrane, phosphorylation-dependent proteolytic processing of ER-localized EIN2 and subsequent translocation of the cleaved EIN2 C-terminal polypeptide (EIN2-CEND) to the nucleus...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28928755/different-preclimacteric-events-in-apple-cultivars-with-modified-ripening-physiology
#9
Vikram Singh, Asya Weksler, Haya Friedman
"Anna" is an early season apple cultivar exhibiting a fast softening and juiciness loss during storage, in comparison to two mid-late season cultivars "Galaxy" and "GD." The poor storage capacity of "Anna" was correlated with high lipid oxidation-related autoluminescence, high respiration and ethylene production rates, associated with high expression of MdACO1, 2, 4, 7, and MdACS1. All cultivars at harvest responded to exogenous ethylene by enhancing ethylene production, typical of system-II. The contribution of pre-climacteric events to the poor storage capacity of "Anna" was examined by comparing respiration and ethylene production rates, response to exogenous ethylene, expression of genes responsible for ethylene biosynthesis and response, and developmental regulators in the three cultivars throughout fruit development...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28903631/evaluation-of-overactive-bladder-and-nocturia-as-a-risk-factor-for-hip-fracture-in-climacteric-women-a-matched-pair-case-control-study
#10
Aysun Karabulut, Serap Simavlı, Ömer Demirtaş, Nusret Ök, Harun Reşit Güngör, Ali Zümrütbaş
The aim of this study was to investigate whether overactive bladder (OAB) influences hip fractures in climacteric women by comparing the frequency of OAB and nocturia symptoms in patients with hip fractures and their age-matched controls in pre-fracture period. A total of 30 climacteric patients with a history of hip fracture were compared to a control group of 51 women in terms of OAB, nocturia and nocturia-QoL. A questionnaire composed of structured questions and Turkish validated versions of the specific questionnaires for OAB, OAB-Quality of Life (OAB-q) and nocturia-QoL was directed to the two groups...
September 14, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28859626/isolation-of-ripening-related-genes-from-ethylene-1-mcp-treated-papaya-through-rna-seq
#11
Yan Hong Shen, Bing Guo Lu, Li Feng, Fei Ying Yang, Jiao Jiao Geng, Ray Ming, Xiao Jing Chen
BACKGROUND: Since papaya is a typical climacteric fruit, exogenous ethylene (ETH) applications can induce premature and quicker ripening, while 1-methylcyclopropene (1-MCP) slows down the ripening processes. Differential gene expression in ETH or 1-MCP-treated papaya fruits accounts for the ripening processes. To isolate the key ripening-related genes and better understand fruit ripening mechanisms, transcriptomes of ETH or 1-MCP-treated, and non-treated (Control Group, CG) papaya fruits were sequenced using Illumina Hiseq2500...
August 31, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28857628/correlation-between-allopregnanolone-levels-and-depressive-symptoms-during-late-menopausal-transition-and-early-postmenopause
#12
Radoslaw Slopien, Nicola Pluchino, Alina Warenik-Szymankiewicz, Stefan Sajdak, Michele Luisi, Panagiotis Drakopoulos, Andrea R Genazzani
OBJECTIVES: This observational, cross-sectional study included 140 women with climacteric symptoms. The aim of the study was to evaluate the correlation between the presence and severity of depressive symptoms and allopregnanolone levels in women during late menopausal transition and early postmenopause. METHODS: The study group was divided into two groups: 45 women in late menopausal transition and 95 early postmenopausal women. We evaluated Kupperman index, Hamilton scale and serum follicle-stimulating hormone, luteinizing hormone, 17β-estradiol, prolactin, total testosterone, dehydroepiandrosterone sulfate and allopregnanolone levels...
August 31, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28855070/can-vitamin-d-supplementation-alone-effective-to-increase-a-physical-fitness-levels-in-post-menopausal-women-with-metabolic-disorders-brief-review
#13
REVIEW
Claudio M Bentes, Monique Resende, Humberto Miranda, Claudia C Netto, Lizanka P F Marinheiro
BACKGROUND: During the climacteric period, occur an aging process of the skin, and promote several decreases in the ability of vitamin D synthesis in an organism and lower levels of Vitamin D may contribute to the appearance of conditions such as osteomalacia, osteoporosis, falls and fractures. AIM: The present brief review focuses on the influence of Vitamin D supplementation alone on physical fitness (strength, endurance, and balance) in postmenopausal with diseases or not...
August 24, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28853078/3111t-c-clock-gene-polymorphism-in-women-with-insomnia
#14
N V Semenova, I M Madaeva, T I Bairova, O A Ershova, O V Kalyuzhnaya, L I Korytov, L I Kolesnikova
Comparative analysis of the frequency distributions of genotypes and alleles of 3111T/C Clock gene polymorphism was carried out in climacteric Caucasian women with and without insomnia. Genotype TT is more incident in women with insomnia (55.5% vs. 42.6% in the control). Allele T predominated in the control and study group and its frequency is higher in women with insomnia. The OR for the risk of insomnia realization is 1.78 (95%CI 1.16-2.75). No association between genotypes and complaints of patients with insomnia is detected...
August 29, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28827038/in-vitro-and-in-situ-characterization-of-triterpene-glycosides-from-cimicifuga-racemosa-extract
#15
L Disch, K Forsch, B Siewert, J Drewe, G Fricker
BACKGROUND: Cimicifuga racemosa products are widely used in the treatment of climacteric symptoms. Aim was to evaluate Cimicifuga racemosa extract Ze 450 according Biopharmaceutics classification system (BCS). METHODS: Triterpene glycosides served as analytical marker and were evaluated for solubility and absorption properties. pH-dependent thermodynamic solubility was tested via shake-flask method according to Yalkowsky (1) and dissolution performance of an herbal medicinal product containing Cimicifuga racemosa extract Ze 450 was assessed...
August 4, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28798491/phytochromobilin-deficiency-impairs-sugar-metabolism-through-the-regulation-of-cytokinin-and-auxin-signaling-in-tomato-fruits
#16
Ricardo Ernesto Bianchetti, Aline Bertinatto Cruz, Bruna Soares Oliveira, Diego Demarco, Eduardo Purgatto, Lázaro Eustáquio Pereira Peres, Magdalena Rossi, Luciano Freschi
Phytochomes and plant hormones have been emerging as important regulators of fleshy fruit biology and quality traits; however, the relevance of phytochrome-hormonal signaling crosstalk in controlling fruit development and metabolism remains elusive. Here, we show that the deficiency in phytochrome chromophore phytochromobilin (PΦB) biosynthesis inhibits sugar accumulation in tomato (Solanum lycopersicum) fruits by transcriptionally downregulating sink- and starch biosynthesis-related enzymes, such as cell-wall invertases, sucrose transporters and ADP-glucose pyrophosphorylases...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28767242/ethylene-control-technologies-in-extending-postharvest-shelf-life-of-climacteric-fruit
#17
Junhua Zhang, Dong Cheng, Baobin Wang, Iqbal Khan, Yonghao Ni
Fresh fruit is important for a healthy diet. However, because of their seasonal production, regional specific cultivation, and perishable nature, it is essential to develop preservation technologies to extend the postharvest shelf life of fresh fruits. Climacteric fruit adopt spoilage because of ethylene, a key hormone associated with the ripening process. Therefore, controlling ethylene activity by following safe and effective approaches is a key to extend the postharvest shelf life of fruit. In this review, ethylene control technologies will be discussed aiming for the need of developing more innovative and effective approaches...
August 30, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28764009/the-chitosan-affects-severely-the-carbon-metabolism-in-mango-mangifera-indica-l-cv-palmer-fruit-during-storage
#18
Gláucia Michelle Cosme Silva, Willian Batista Silva, David B Medeiros, Acácio Rodrigues Salvador, Maria Helena Menezes Cordeiro, Natália Martins da Silva, Diederson Bortolini Santana, Gisele Polete Mizobutsi
Mango is a highly perishable fruit with a short post-harvest time due to the intense metabolic activity after harvesting. In attempt to evaluate the effects of chitosan in mango fruits, it was treated with 0%, 1%, 2% or 3% of chitosan solutions, placed into plastic trays, and stored at room temperature. Changes in physical and chemical parameters were evaluated. Chitosan delayed the climacteric peak, water loss and firmness. Further, few changes in soluble solid content, titratable acidity, pH of the pulp as well as in sugar content and decreased starch degradation were observed...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28742430/sexual-life-of-women-in-the-climacterium-a-community-based-study
#19
Tugba Andac, Ergul Aslan
Our purpose of conducting this community-based study was to determine sexual functions of women in climacterium and effects of menopausal symptoms on sexual functions. It was descriptive, cross-sectional and community-based. The study sample consisted of 282 climacteric women. Menopause Rating Scale, Female Sexual Function Index and Sexual Satisfaction Scale for Women were used for data collection. The total score was 13.42±8.82 for Menopause Rating Scale, 18.73±9.79 for Female Sexual Function Index and 82...
July 25, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28717331/knowledge-and-awareness-of-first-aid-of-avulsed-tooth-among-physicians-and-nurses-of-hospital-emergency-department
#20
Sudeep Sreepad Iyer, Antarmayee Panigrahi, Shalini Sharma
INTRODUCTION: Physicians and nurses of emergency department are often the first line of qualified health-care providers attending the patient in person or parent's query over phone reporting immediately following the dental avulsion. Prompt action by them becomes the decisive factor in survival and prognosis of the tooth. Although a few researchers have evaluated knowledge of emergency room physicians, there is scanty of reports concerning nurses who play a climacteric role. MATERIALS AND METHODS: A 10-item questionnaire regarding clinical situation apropos dental injury and tooth avulsion, inquiring knowledge of physicians and nurses was administered to 150 each of nursing professionals and physicians of the emergency department...
April 2017: Journal of Pharmacy & Bioallied Sciences
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