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Climacteric

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https://www.readbyqxmd.com/read/28717331/knowledge-and-awareness-of-first-aid-of-avulsed-tooth-among-physicians-and-nurses-of-hospital-emergency-department
#1
Sudeep Sreepad Iyer, Antarmayee Panigrahi, Shalini Sharma
INTRODUCTION: Physicians and nurses of emergency department are often the first line of qualified health-care providers attending the patient in person or parent's query over phone reporting immediately following the dental avulsion. Prompt action by them becomes the decisive factor in survival and prognosis of the tooth. Although a few researchers have evaluated knowledge of emergency room physicians, there is scanty of reports concerning nurses who play a climacteric role. MATERIALS AND METHODS: A 10-item questionnaire regarding clinical situation apropos dental injury and tooth avulsion, inquiring knowledge of physicians and nurses was administered to 150 each of nursing professionals and physicians of the emergency department...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28706523/identification-of-optimal-reference-genes-for-normalization-of-qpcr-analysis-during-pepper-fruit-development
#2
Yuan Cheng, Xin Pang, Hongjian Wan, Golam J Ahammed, Jiahong Yu, Zhuping Yao, Meiying Ruan, Qingjing Ye, Zhimiao Li, Rongqing Wang, Yuejian Yang, Guozhi Zhou
Due to its high sensitivity and reproducibility, quantitative real-time PCR (qPCR) is practiced as a useful research tool for targeted gene expression analysis. For qPCR operations, the normalization with suitable reference genes (RGs) is a crucial step that eventually determines the reliability of the obtained results. Although pepper is considered an ideal model plant for the study of non-climacteric fruit development, at present no specific RG have been developed or validated for the qPCR analyses of pepper fruit...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28692413/effects-of-astaxanthin-on-liver-and-leukocyte-parameters-in-healthy-climacteric-women-preliminary-data
#3
Jui-Tung Chen, Kazuhiko Kotani
No abstract text is available yet for this article.
July 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28692231/-the-menopausal-hormone-therapy-in-2016
#4
Evangelia Pavlidou, Paul Pirtea, Isabelle Streuli
The menopausal hormone therapy (MHT) is the first line treatment for climacteric symptoms related to estrogen deficiency. A personalized evaluation of the benefit-risk ratio should precede a MHT prescription, and take into consideration cardiovascular, thromboembolic, oncological and osteoporosis risks. MHT should be prescribed at the lowest effective dose and for the shortest duration, respecting the window of opportunity in the 10 years following menopause or before the age of 60 years. The choice of the MHT type depends on the patient's profile, her medical history and personal preferences, with the aim of improving quality of life from a physical, psychological and sexual point of view...
October 26, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28680438/abscisic-acid-is-a-major-regulator-of-grape-berry-ripening-onset-new-insights-into-aba-signaling-network
#5
Stefania Pilati, Giorgia Bagagli, Paolo Sonego, Marco Moretto, Daniele Brazzale, Giulia Castorina, Laura Simoni, Chiara Tonelli, Graziano Guella, Kristof Engelen, Massimo Galbiati, Claudio Moser
Grapevine is a world-wide cultivated economically relevant crop. The process of berry ripening is non-climacteric and does not rely on the sole ethylene signal. Abscisic acid (ABA) is recognized as an important hormone of ripening inception and color development in ripening berries. In order to elucidate the effect of this signal at the molecular level, pre-véraison berries were treated ex vivo for 20 h with 0.2 mM ABA and berry skin transcriptional modulation was studied by RNA-seq after the treatment and 24 h later, in the absence of exogenous ABA...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28671844/sensitivity-to-ethephon-degreening-treatment-is-altered-by-blue-led-light-irradiation-in-mandarin-fruit
#6
Lili Deng, Ziyi Yuan, Jiao Xie, Shixiang Yao, Kaifang Zeng
Although citrus fruits are not climacteric, exogenous ethylene is widely used in the degreening treatment of citrus fruits. Irradiation with blue light-emitting diode (LED) light (450 nm) for 10 h can promote the formation of good coloration of ethephon-degreened fruit. This study evaluated the effect of blue LED light irradiation on the pigments contents of ethephon-degreened fruit, and evaluated whether the blue LED light irradiation could influence the sensitivity of mandarin fruit to ethylene. The results indicated that blue light can accelerate the color change of ethephon-degreened fruit, accompanied by changes in plastid ultrastructure and chlorophyll and carotenoid contents...
July 3, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28662086/abscisic-acid-pathway-involved-in-the-regulation-of-watermelon-fruit-ripening-and-quality-trait-evolution
#7
Yanping Wang, Shaogui Guo, Shouwei Tian, Jie Zhang, Yi Ren, Honghe Sun, Guoyi Gong, Haiying Zhang, Yong Xu
Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) is a non-climacteric fruit. The modern sweet-dessert watermelon is the result of years of cultivation and selection for fruits with desirable qualities. To date, the mechanisms of watermelon fruit ripening, and the role of abscisic acid (ABA) in this process, has not been well understood. We quantified levels of free and conjugated ABA contents in the fruits of cultivated watermelon (97103; C. lanatus subsp. vulgaris), semi-wild germplasm (PI179878; C...
2017: PloS One
https://www.readbyqxmd.com/read/28649907/non-menopausal-endocrine-and-non-endocrine-causes-of-flushing-and-sweating
#8
Vikram Lal, Yaasir H Mamoojee, Richard Quinton
Hot flushes and generalised sweating are relatively common presenting complaints, with hypogonadism an important differential diagnosis in both sexes and menopause being the most typical cause in females of climacteric age. However, a variety of other conditions do need to be carefully considered in respect of eugonadal individuals and also for those hypogonadal ones where properly dosed sex steroid replacement has failed to control flushing and sweating, or where the presentation is atypical. Alternative aetiologies may be immediately obvious from the history and physical examination, but more unusual conditions may require deeper scrutiny...
January 1, 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28649100/-aging-and-homeostasis-sex-hormones-and-aging
#9
Keizo Ohnaka
The decline in sex hormones along with aging is suggested to be involved in age-associated diseases such as cardiovascular diseases, osteoporosis, and dementia. The decrease of estrogen level after menopause is related to osteoporosis in addition to climacteric disturbance in women, while that of testosterone to sarcopenia, osteoporosis and late-onset hypogonadism in men. New treatment strategy is expected for targeting age-associated diseases against the decreased level of sex hormones.
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28639461/hormonal-contraception-and-breast-cancer-what-more-do-we-need-to-know
#10
Jo Marsden
Most women use hormonal contraception for more than 30 years and for many, this may involve exposure in their older reproductive years when baseline breast cancer risk rises steeply. Overall, the risk of breast cancer diagnosis with exposure to hormonal contraception is very small and outweighed by its contraceptive benefits but despite this, there are still outstanding questions for all methods used in clinical practice due to paucity of available evidence, lack of which should not be taken to imply safety...
January 1, 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28609393/menopausal-transition-in-southern-europe-comparative-study-of-women-in-serbia-and-portugal
#11
Jelena Dotlic, Filipa Pimenta, Nikolina Kovacevic, Isabel Leal, Joao Maroco, Wulf Utian, Tatjana Gazibara
OBJECTIVE: The aim of this study was to assess and compare general menopausal quality of life in Serbia and Portugal. METHODS: In all, 1,503 women aged between 40 and 65 years from Belgrade, Serbia, and Lisbon, Portugal, were included in the study. A sociodemographic questionnaire and the Utian Quality of Life (UQOL) scale were used in data collection. RESULTS: The average age of women was 50 (SD = 5.61) years. Serbian and Portuguese women differed in all sociodemographic characteristics except for body mass index (BMI) and relationship status...
June 12, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28593720/phytoestrogen-rich-natural-preparation-for-treatment-of-climacteric-syndrome-and-atherosclerosis-prevention-in-perimenopausal-women
#12
T V Kirichenko, V A Myasoedova, V A Orekhova, A L Ravani, N A Nikitina, A V Grechko, I A Sobenin, A N Orekhov
The present study evaluated the risks and benefits of phytoestrogen treatment in healthy perimenopausal women in relation to the dynamics of climacteric syndrome and progression of atherosclerosis. Study participants were treated with placebo or phytoestrogen-rich natural preparation Karinat based on grape (Vitis vinifera) seeds, green tea (Camellia sinensis) leaves, hop (Hunulus lupulus) cone powder and garlic (Allium sativum) powder. The dynamics of climacteric syndrome was evaluated by Kupperman Index and Utian Quality of Life Scale...
June 8, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28588485/beneficial-effects-and-toxicity-studies-of-xian-ling-gu-bao-on-bone-metabolism-in-ovariectomized-rats
#13
Hao Wu, Qingxiang Zhong, Jing Wang, Man Wang, Fang Fang, Zhi Xia, Rongling Zhong, Houcai Huang, Zhongcheng Ke, Yingjie Wei, Liang Feng, Ziqi Shi, E Sun, Jie Song, Xiaobin Jia
Xian-ling-gu-bao (XLGB) is a well-known patented traditional Chinese prescription widely used to treat osteoporosis, osteoarthritis, aseptic bone necrosis, or climacteric syndrome. However, recent reports have suggested that XLGB may cause liver injury in humans. In the present study, we aimed to evaluate the efficacy of XLGB in the prevention of osteoporosis in the zebrafish and ovariectomized (OVX) rats, both of which have been used as osteoporosis models. The safety of XLGB after long-term administration to OVX rats was also assessed...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28584579/effect-of-soy-isoflavones-supplement-on-climacteric-symptoms-bone-biomarkers-and-quality-of-life-in-korean-postmenopausal-women-a-randomized-clinical-trial
#14
Hansongyi Lee, Ryowon Choue, Hyunjung Lim
BACKGROUND/OBJECTIVES: Soy isoflavones are expected to improve menopausal symptoms and osteoporosis in women. However, their efficacy is still inconclusive, and there was limited data for postmenopausal women in South Korea. We examined the effects of soy isoflavones on climacteric symptoms, bone biomarkers, and quality of life in Korean postmenopausal women. SUBJECTS/METHODS: A randomized, double-blind study design was used. Eighty-seven participants who had undergone natural menopause were randomly administered either 70 mg/day isoflavones (n = 43) or placebo (n = 41) for 12 weeks...
June 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28574385/-connective-tissue-metabolic-features-in-climacteric-syndrome-s-patients-with-various-types-of-menopause
#15
O Gryshchenko, I Vasylieva, K Gryshchuk
The purpose of the study was investigation of the connective tissue metabolic features among women with menopausal syndrome (MS) and MS, in which the arthropathic syndrome is leading and comparative analysis of the connective tissue indicators exchange during menopause caused in a surgical and natural way. We examined 70 women in total, menopause duration they accounted for 1,95±1,1 years, it came both as natural, and as a result of a surgery. The main group included 40 women with MS with leading arthropathic syndrome...
April 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28573485/a-lateral-flow-colloidal-gold-based-immunoassay-for-rapid-detection-of-miroestrol-in-samples-of-white-kwao-krua-a-phytoestrogen-rich-plant
#16
Tharita Kitisripanya, Chadathorn Inyai, Jukrapun Komaikul, Supaluk Krittanai, Thaweesak Juengwatanatrakul, Seiichi Sakamoto, Hiroyuki Tanaka, Satoshi Morimoto, Waraporn Putalun
White Kwao Krua (WKK)-derived products have been used worldwide as dietary supplements to relieve climacteric symptoms in menopausal women. Miroestrol is a unique chromene found in WKK tuberous roots that corresponds to the estrogenic activity of WKK. However, miroestrol naturally accumulates at low levels in WKK samples, which are difficult to detect. The development of a rapid and sensitive assay to detect miroestrol in numerous products derived from this plant would be a practical and useful method to guarantee the quality of raw materials...
June 1, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28562488/does-obesity-increase-the-risk-of-hot-flashes-among-midlife-women-a-population-based-study
#17
Sylvio Saccomani, Jeffrey Frederico Lui-Filho, Cassia Raquel Juliato, Jose Roberto Gabiatti, Adriana Orcesi Pedro, Lucia Costa-Paiva
OBJECTIVE: To evaluate the association between vasomotor symptoms and obesity in climacteric women. METHODS: We conducted a cross-sectional population-based study of 749 women aged 45 to 60 years. The dependent variable was intensity of menopausal symptoms evaluated by the menopause rating scale questionnaire. Independent variables were sociodemographic and clinical characteristics, and obesity evaluated by body mass index. RESULTS: There was no significant difference in the majority of clinical and sociodemographic characteristics between the body mass index groups...
May 29, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28550149/the-jasmonate-activated-transcription-factor-mdmyc2-regulates-ethylene-response-factor-and-ethylene-biosynthetic-genes-to-promote-ethylene-biosynthesis-during-apple-fruit-ripening
#18
Tong Li, Yaxiu Xu, Lichao Zhang, Yinglin Ji, Dongmei Tan, Hui Yuan, Aide Wang
The plant hormone ethylene is critical for ripening in climacteric fruits, including apple (Malus domestica). Jasmonate (JA) promotes ethylene biosynthesis in apple fruit, but the underlying molecular mechanism is unclear. Here, we found that JA-induced ethylene production in apple fruit is dependent on the expression of MdACS1, an ACC synthase gene involved in ethylene biosynthesis. The expression of MdMYC2, encoding a transcription factor involved in the JA signaling pathway, was enhanced by MeJA treatment in apple fruits, and MdMYC2 directly bound to the promoters of both MdACS1 and the ACC oxidase gene MdACO1 and enhanced their transcription...
June 2017: Plant Cell
https://www.readbyqxmd.com/read/28546801/the-safety-and-tolerance-of-phytotherapies-in-menopausal-medicine-a-review-of-the-literature
#19
REVIEW
Piotr Czuczwar, Tomasz Paszkowski, Marek Lisiecki, Sławomir Woźniak, Anna Stępniak
Phytoestrogens are polyphenol, non-steroidal substances of plant origin, resembling 17β-estradiol in structure. These substances can act as either agonists or antagonists of oestrogen receptors α and β. Phytoestrogens are widely used to alleviate menopausal symptoms, such as hot flushes and night sweats. Most of the currently available products of plant origin registered to soften climacteric symptoms consist of extracts obtained from soy, red clover, or black cohosh. Non-hormonal phytotherapy is a new alternative for patients suffering from menopausal symptoms...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28538601/psychometric-properties-of-the-finnish-version-of-the-women-s-health-questionnaire
#20
Riina E Katainen, Janne R Engblom, Tero J Vahlberg, Päivi Polo-Kantola
OBJECTIVE: The Women's Health Questionnaire (WHQ) is a validated and commonly used instrument for measuring climacteric-related symptoms. A revised version was previously developed. However, validation in a Finnish population is lacking. As it is important to use qualified instruments, we performed a validation study of the WHQ in a Finnish population. METHODS: In all, 3,421 women, aged 41 to 54 years, formed the study population. In the original 36-item WHQ, the items were rated on a 1 to 4 scale and on a binary scale (0-1)...
May 22, 2017: Menopause: the Journal of the North American Menopause Society
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