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Xiangyan Ruan, Yamei Cui, Juan Du, Fengyu Jin, Alfred Otto Mueck
INTRODUCTION: The climacteric symptoms during peri- and postmenopause have not been extensively studied in China. To further understanding of the characteristics of Chinese women during their menopausal transition, the aim of the study was to compare the prevalence and severity of climacteric symptoms of peri- and postmenopausal Chinese women. METHODS: The retrospective descriptive study was carried out in perimenopausal and postmenopausal women from 20 provinces of China who visited Beijing Obstetrics & Gynecology hospital during 2008-2015...
October 21, 2016: Journal of Psychosomatic Obstetrics and Gynaecology
I G Shestakova, V E Radzinsky, M B Khamoshina
Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical and psychological consequences. Despite the description of different genetic, immune and iatrogenic factors of POI, the etiology of most cases of this disease are unexplained, and optimal management strategies are still unclear. Recent data showed that POI may have a long period of oligomenorrhea before the fully developed form (complete ovarian failure stage), with the occurrence of amenorrhea and climacteric symptoms...
October 2016: Gynecological Endocrinology
V E Radzinskii, I V Kuznetsova, Y B Uspenskaya, N B Repina, Y K Gusak, O M Zubova, D I Burchakov, A A Osmakova
Peri- and postmenopausal women commonly suffer from climacteric symptoms. We evaluated the effectiveness and safety of dietary supplement Amberen to relieve vasomotor and psychosomatic symptoms during the course of a 3-month, randomized, double-blind, placebo-controlled study. General clinical assessment, evaluation using the Greene climacteric test and Spielberger-Hanin test, determination of plasma levels of gonadotropins, estradiol, leptin and apolipoproteins were used to evaluate 42-60-year-old women with vasomotor and psychosomatic menopausal symptoms...
October 2016: Gynecological Endocrinology
Gülten Güvenç, Semra Kocaöz, Gülşah Kök
Urinary incontinence (UI) is a common health problem and negatively affects the quality of life of women who are afflicted. The aim of the study is to explore the prevalence and risk factors of UI among climacteric Turkish women and to examine the effects of UI on their quality of life. This cross-sectional study was conducted with 258 women aged 40-64 years who visited the outpatient clinic in Ankara, Turkey, between 15 June 2012 and 15 January 2013. The data were collected using the International Consultation on Incontinence Questionnaire Short Form and the Incontinence Quality of Life Questionnaire...
October 19, 2016: International Journal of Nursing Practice
Padma Nimmakayala, Yan R Tomason, Venkata L Abburi, Alejandra Alvarado, Thangasamy Saminathan, Venkata G Vajja, Germania Salazar, Girish K Panicker, Amnon Levi, William P Wechter, James D McCreight, Abraham B Korol, Yefim Ronin, Jordi Garcia-Mas, Umesh K Reddy
Melon (Cucumis melo L.) is a phenotypically diverse eudicot diploid (2n = 2x = 24) has climacteric and non-climacteric morphotypes and show wide variation for fruit firmness, an important trait for transportation and shelf life. We generated 13,789 SNP markers using genotyping-by-sequencing (GBS) and anchored them to chromosomes to understand genome-wide fixation indices (Fst) between various melon morphotypes and genomewide linkage disequilibrium (LD) decay. The FST between accessions of cantalupensis and inodorus was 0...
2016: Frontiers in Plant Science
Marian Bittner, Regina Schenk, Andreas Springer, Matthias F Melzig
INTRODUCTION: The medicinal plant Actaea racemosa L. (Ranunculaceae, aka black cohosh) is widely used to treat climacteric complaints as an alternative to hormone substitution. Recent trials prove efficacy and safety of the approved herbal medicinal products from extracts of pharmaceutical quality. This led to worldwide increasing sales. A higher demand for the plant material results in problems with economically motivated adulteration. Thus, reliable tools for herbal drug authentication are necessary...
November 2016: Phytochemical Analysis: PCA
Stefanie I Siebler, Ursula Gresser, Barbara M Richartz
Objective. This study aims to evaluate the effect of daily dietary nutritional supplement on somatic, psychological, and urogenital symptoms in postmenopausal women. Material and Methods. In this study 28 healthy, symptomatic, peri- and postmenopausal women of 47-67 years of age were allocated to use the nutritional supplement JuicePLUS+®. Primary research parameters: Menopause Rating Scale (MRS) was used to assess menopausal symptoms at baseline and after 8 and 16 weeks of treatment. Secondary parameters: proliferation behaviour of vaginal smear was scored at baseline and after treatment...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
Monik Maryelle Moreira da Silva, Edson Pablo da Silva, Flávio Alves da Silva, Felipe Iwagaki B Ogando, Claudio Lima de Aguiar, Clarissa Damiani
It was evaluated the physiological aspects of the cagaita (Eugenia dysenterica) development, from anthesis to ripening. The fruits have been subjected to physical and chemical analysis during the fruit life cycle. The total fruit development comprised 37days. There was a steady increase in the total mass of the fruits and significant increase in transverse and longitudinal diameter, adjusting the double sigmoidal behavior in response to changes in the time. From the 23rd DAA, it was observed the beginning of loss of firmness, increase in total and soluble pectin content and a decrease in starch content...
February 15, 2017: Food Chemistry
Iwona Bojar, Oleh Lyubinets, Jozef Novotny, Yaroslav Stanchak, Evgenii Tiszczenko, Alfred Owoc, Dorota Raczkiewicz
The objective of the study was analysis of the occurrence and intensity of menopausal symptoms in postmenopausal women from Poland, Belarus, Ukraine, Czech Republic, Slovakia and Poland. The study was conducted during the period 2014-2015 among postmenopausal women living in the areas of Poland, Belarus, Ukraine, Czech Republic and Slovakia. The degree of menopausal complaints was assessed using the Kupperman Menopausal Index and Greene Climacteric Scale. The respondents were additionally asked about age, educational level, place of residence, marital status and age at last menstrual period...
September 2016: Annals of Agricultural and Environmental Medicine: AAEM
Angelo Cagnacci, Federica Palma, Maria Maddalena Carbone, Giovanni Grandi, Anjeza Xholli
OBJECTIVE: The aim of the study was to evaluate whether climacteric symptoms are related to urinary incontinence (UI) in postmenopausal women. METHODS: A cross-sectional investigation was performed on 1,502 postmenopausal women attending the outpatient service for menopause at a University Hospital. Data regarding climacteric symptoms, evaluated by the Greene Climacteric Scale, objective pelvic floor defects, and UI of any type, were retrieved from an electronic database...
September 19, 2016: Menopause: the Journal of the North American Menopause Society
Tahereh Eftekhar, Mahboobeh Dashti, Mamak Shariat, Fedyeh Haghollahi, Firoozeh Raisi, Akram Ghahghaei-Nezamabadi
Objective: To determine the prevalence of sexual problems in Iranian women and association of sexual dysfunction with menopausal symptoms. Materials and methods: In this cross-sectional study, 151 married women with the age of 40-60 yearsold who were referred for treatmentto Department of Gynecology in Vali-e-Asr Hospital (Tehran, Iran) from April to July 2012, were recruited. They were evaluated concerning their sexual function in the domains of desire, arousal, lubrication, orgasm, satisfaction and pain with the female sexual function index (FSFI) questionnaire...
June 2016: Journal of Family & Reproductive Health
Nick Panay, Anna Fenton
No abstract text is available yet for this article.
October 2016: Climacteric: the Journal of the International Menopause Society
Laura Medina-Puche, Rosario Blanco-Portales, Francisco Javier Molina-Hidalgo, Guadalupe Cumplido-Laso, Nicolás García-Caparrós, Enriqueta Moyano-Cañete, José Luis Caballero-Repullo, Juan Muñoz-Blanco, Antonio Rodríguez-Franco
Strawberry is an ideal model for studying the molecular biology of the development and ripening of non-climacteric fruits. Hormonal regulation of gene expression along all these processes in strawberries is still to be fully elucidated. Although auxins and ABA have been pointed out as the major regulatory hormones, few high-throughput analyses have been carried out to date. The role for ethylene and gibberellins as regulatory hormones during the development and ripening of the strawberry fruit remain still elusive...
September 10, 2016: Functional & Integrative Genomics
Luís Carlos, Lóris Aparecida Prado da Cruz, Vanessa Cristina Leopoldo, Fabrício Ribeiro de Campos, Ana Maria de Almeida, Renata Cristina de Campos Pereira Silveira
OBJECTIVE: to identify and synthesize the evidence from randomized clinical trials that tested the effectiveness of traditional Chinese acupuncture in relation to sham acupuncture for the treatment of hot flashes in menopausal women with breast cancer. METHOD: systematic review guided by the recommendations of the Cochrane Collaboration. Citations were searched in the following databases: MEDLINE via PubMed, Web of Science, CENTRAL, CINAHL, and LILACS. A combination of the following keywords was used: breast neoplasm, acupuncture, acupuncture therapy, acupuncture points, placebos, sham treatment, hot flashes, hot flushes, menopause, climacteric, and vasomotor symptoms...
2016: Revista Latino-americana de Enfermagem
Alice Tadiello, Sara Longhi, Marco Moretto, Alberto Ferrarini, Paola Tononi, Brian Farneti, Nicola Busatto, Urska Vrhovsek, Alessandra Dal Molin, Carla Avanzato, Franco Biasioli, Luca Cappellin, Matthias Scholz, Riccardo Velasco, Livio Trainotti, Massimo Delledonne, Fabrizio Costa
Apple (Malus x domestica Borkh.) is a model species for studying the metabolic changes that occur at the onset of ripening in fruit crops, and the physiological mechanisms that are governed by the hormone ethylene. In this study, to dissect the climacteric interplay in apple, a multidisciplinary approach was employed. To this end, a comprehensive analysis of gene expression together with the investigation of several physiological entities (texture, volatilome and content of polyphenolic compounds) was performed throughout fruit development and ripening...
October 5, 2016: Plant Journal: for Cell and Molecular Biology
Veronika A Myasoedova, Tatyana V Kirichenko, Alexandra A Melnichenko, Varvara A Orekhova, Alessio Ravani, Paolo Poggio, Igor A Sobenin, Yuri V Bobryshev, Alexander N Orekhov
The risk of cardiovascular disease and atherosclerosis progression is significantly increased after menopause, probably due to the decrease of estrogen levels. The use of hormone replacement therapy (HRT) for prevention of cardiovascular disease in older postmenopausal failed to meet expectations. Phytoestrogens may induce some improvements in climacteric symptoms, but their effect on the progression of atherosclerosis remains unclear. The reduction of cholesterol accumulation at the cellular level should lead to inhibition of the atherosclerotic process in the arterial wall...
2016: International Journal of Molecular Sciences
Mortaza Ebrahimi, Siti Nor Akmar Abdullah, Maheran Abdul Aziz, Parameswari Namasivayam
CBF/DREB1 is a group of transcription factors that are mainly involved in abiotic stress tolerance in plants. They belong to the AP2/ERF superfamily of plant-specific transcription factors. A gene encoding a new member of this group was isolated from ripening oil palm fruit and designated as EgCBF3. The oil palm fruit demonstrates the characteristics of a climacteric fruit like tomato, in which ethylene has a major impact on the ripening process. A transgenic approach was used for functional characterization of the EgCBF3, using tomato as the model plant...
September 1, 2016: Journal of Plant Physiology
Istvan Merchenthaler, Malcolm Lane, Gauri Sabnis, Angela Brodie, Vien Nguyen, Laszlo Prokai, Katalin Prokai-Tatrai
Estrogen deprivation has a profound effect on the female brain. One of the most obvious examples of this condition is hot flushes. Although estrogens relieve these typical climacteric symptoms, many women do not want to take them owing to unwanted side-effects impacting, for example, the uterus, breast and blood. Therefore, there is a need for developing safer estrogen therapies. We show here that treatment with 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), a novel brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain...
2016: Scientific Reports
Tong Li, Zhongyu Jiang, Lichao Zhang, Dongmei Tan, Yun Wei, Hui Yuan, Tianlai Li, Aide Wang
Fruit ripening in climacteric fruit requires the gaseous phytohormone ethylene. Although ethylene signaling has been well studied, knowledge of the transcriptional regulation of ethylene biosynthesis is still limited. Here we show that an apple (Malus domestica) ethylene response factor, MdERF2, negative affects ethylene biosynthesis and fruit ripening by suppressing the transcription of MdACS1, a gene that is critical for ripening-related ethylene biosynthesis. MdERF2 expression was suppressed by ethylene during apple fruit ripening, and we observed that MdERF2 bound to the promoter of MdACS1 and directly suppressed its transcription...
August 1, 2016: Plant Journal: for Cell and Molecular Biology
Natalia Teribia, Verónica Tijero, Sergi Munné-Bosch
Sweet cherries are highly appreciated by consumers worldwide and are usually cold-stored during postharvest to prevent over-ripening before distribution to the market. Sweet cherry is a non-climacteric fruit, for which ripening is known to be regulated by abscisic acid. Here we aimed to examine the hormone profiles, including measurements of abscisic acid, auxins, cytokinins and gibberellins by ultrahigh performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS), in relation to variations in sugar and anthocyanin contents, during growth and ripening of this fruit...
December 25, 2016: New Biotechnology
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