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Hematology, biochemistry, biomedical, sciences

Anthony Nicholson, Rachel D Malcolm, Phillip L Russ, Kristin Cough, Chadi Touma, Rupert Palme, Michael V Wiles
Increased numbers of mice housed per cage (that is, increased housing density) is seen as 1 way to reduce the costs of conducting biomedical research. Current empirically derived guidelines are based on the area provided per mouse depending on body weight as documented in the Guide for the Care and Use of Laboratory Animals. The current study aimed to provide a more scientific basis for housing density by examining the response of C57BL/6J and BALB/cJ mice to increased housing density from weaning to 5 mo of age, to determine those parameters most useful for future larger-scale studies...
November 2009: Journal of the American Association for Laboratory Animal Science: JAALAS
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