Anna R Smith, Pi-I D Lin, Sheryl L Rifas-Shiman, Karen M Switkowski, Abby F Fleisch, Robert O Wright, Brent Coull, Emily Oken, Marie-France Hivert, Andres Cardenas
BACKGROUND: Nonessential metals have endocrine disrupting properties, interfere with cellular processes, generate reactive oxygen and deplete antioxidants, while essential metals and vitamins act as antioxidants. The extent to which prenatal metals and vitamins are associated with cord blood hormones involved in maternal and fetal metabolic and growth processes is unknown. METHODS: We measured six nonessential (arsenic, barium, cadmium, cesium, lead, mercury) and four essential (magnesium, manganese, selenium, zinc) metals and trace elements, and two vitamins (B12 and folate) in first trimester blood from participants in the longitudinal pre-birth Project Viva cohort, who were recruited between 1999-2002 in eastern Massachusetts...
December 2023: Global reproductive health