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https://www.readbyqxmd.com/read/28538320/the-effects-of-a-heel-wedge-on-hip-pelvis-and-trunk-biomechanics-during-squatting-in-resistance-trained-individuals
#1
Jesse M Charlton, Connor A Hammond, Christopher K Cochrane, Gillian L Hatfield, Michael A Hunt
Charlton, JM, Hammond, CA, Cochrane, CK, Hatfield, GL, and Hunt, MA. The effects of a heel wedge on hip, pelvis, and trunk biomechanics during squatting in resistance trained individuals. J Strength Cond Res 31(6): 1678-1687, 2017-Barbell back squats are a popular exercise for developing lower extremity strength and power. However, this exercise has potential injury risks, particularly to the lumbar spine, pelvis, and hip joint. Previous literature suggests heel wedges as a means of favorably adjusting trunk and pelvis kinematics with the intention of reducing such injury risks...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28538307/can-cold-water-immersion-enhance-recovery-in-elite-olympic-weightlifters-an-individualized-perspective
#2
Jan Schimpchen, Maximilian Wagner, Alexander Ferrauti, Michael Kellmann, Mark Pfeiffer, Tim Meyer
Schimpchen, J, Wagner, M, Ferrauti, A, Kellmann, M, Pfeiffer, M, and Meyer, T. Can cold water immersion enhance recovery in elite Olympic weightlifters? An individualized perspective. J Strength Cond Res 31(6): 1569-1576, 2017-We investigated whether cold water immersion (CWI) after intensive training sessions can enhance recovery in elite Olympic weightlifters, taking into account each athlete's individual response pattern. The entire German male Olympic weightlifting national team participated in the study (n = 7), ensuring collection of data from elite athletes only...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28537195/caffeine-ingestion-acutely-enhances-muscular-strength-and-power-but-not-muscular-endurance-in-resistance-trained-men
#3
Jozo Grgic, Pavle Mikulic
The goal of this randomized, double-blind, cross-over study was to assess the acute effects of caffeine ingestion on muscular strength and power, muscular endurance, rate of perceived exertion (RPE), and pain perception (PP) in resistance-trained men. Seventeen volunteers (mean ± SD: age = 26 ± 6 years, stature = 182 ± 9 cm, body mass = 84 ± 9 kg, resistance training experience = 7 ± 3 years) consumed placebo or 6 mg kg(-1) of anhydrous caffeine 1 h before testing...
May 24, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28526779/the-phenotypic-spectrum-of-nephropathies-associated-with-mutations-in-diacylglycerol-kinase-%C3%AE%C2%B5
#4
Karolis Azukaitis, Eva Simkova, Mohammad Abdul Majid, Matthias Galiano, Kerstin Benz, Kerstin Amann, Clemens Bockmeyer, Radha Gajjar, Kevin E Meyers, Hae Il Cheong, Bärbel Lange-Sperandio, Therese Jungraithmayr, Véronique Frémeaux-Bacchi, Carsten Bergmann, Csaba Bereczki, Monika Miklaszewska, Dorottya Csuka, Zoltán Prohászka, Patrick Gipson, Matthew G Sampson, Mathieu Lemaire, Franz Schaefer
The recent discovery of mutations in the gene encoding diacylglycerol kinase ε (DGKE) identified a novel pathophysiologic mechanism leading to HUS and/or MPGN. We report ten new patients from eight unrelated kindreds with DGKE nephropathy. We combined these cases with all previously published cases to characterize the phenotypic spectrum and outcomes of this new disease entity. Most patients presented with HUS accompanied by proteinuria, whereas a subset of patients exhibited clinical and histologic patterns of MPGN without TMA...
May 19, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28502972/distribution-innervation-and-cellular-organization-of-taste-buds-in-the-sea-catfish-plotosus-japonicus
#5
Tatsufumi Nakamura, Naoki Matsuyama, Masato Kirino, Masanori Kasai, Sadao Kiyohara, Takanori Ikenaga
The gustatory system of the sea catfish Plotosus japonicus, like that of other catfishes, is highly developed. To clarify the details of the morphology of the peripheral gustatory system of Plotosus, we used whole-mount immunohistochemistry to investigate the distribution and innervation of the taste buds within multiple organs including the barbels, oropharyngeal cavity, fins (pectoral, dorsal, and caudal), and trunk. Labeled taste buds could be observed in all the organs examined. The density of the taste buds was higher along the leading edges of the barbels and fins; this likely increases the chance of detecting food...
May 13, 2017: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/28493377/neonatal-myeloid-derived-suppressor-cells-show-reduced-apoptosis-and-immunosuppressive-activity-upon-infection-with-escherichia-coli
#6
Anja Leiber, Julian Schwarz, Natascha Köstlin, Bärbel Spring, Birgit Fehrenbach, Nenad Katava, Christian F Poets, Christian Gille
BACKGROUND: Susceptibility to infection during the neonatal period and reduced control of inflammation in neonates are attributed to immunosuppression persisting from fetal life. Myeloid-derived suppressor cells (MDSCs) are immature myeloid progenitors with suppressive activity and increased numbers in cord blood. We hypothesized that MDSCs contribute to innate host defence in neonates, paralleled by anti-inflammatory signalling. METHODS: Phagocytic activity, infection induced apoptosis, expression of B-cell lymphoma (Bcl)-2 family proteins, production of reactive oxygen species (ROS), cytokine production and T-cell suppression of neonatal granulocytic-MDSCs (G-MDSCs) after infection with Escherichia coli (E...
May 11, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/28493373/the-novel-%C3%AE-b-crystallin-cryab-mutation-p-d109g-causes-restrictive-cardiomyopathy
#7
Andreas Brodehl, Anna Gaertner-Rommel, Bärbel Klauke, Simon Andre Grewe, Ilona Schirmer, Andreas Peterschröder, Lothar Faber, Matthias Vorgerd, Jan Gummert, Dario Anselmetti, Uwe Schulz, Lech Paluszkiewicz, Hendrik Milting
Restrictive cardiomyopathy (RCM) is a rare heart disease characterized by diastolic dysfunction and atrial enlargement. The genetic etiology of RCM is not completely known. We identified by a next-generation sequencing panel the novel CRYAB missense mutation c.326A>G, p.D109G in a small family with RCM in combination with skeletal myopathy with an early onset of the disease. CRYAB encodes αB-Crystallin, a member of the small heat shock protein family, which is highly expressed in cardiac and skeletal muscle...
May 11, 2017: Human Mutation
https://www.readbyqxmd.com/read/28492526/differentiation-of-cardiomyocytes-and-generation-of-human-engineered-heart-tissue
#8
Kaja Breckwoldt, David Letuffe-Brenière, Ingra Mannhardt, Thomas Schulze, Bärbel Ulmer, Tessa Werner, Anika Benzin, Birgit Klampe, Marina C Reinsch, Sandra Laufer, Aya Shibamiya, Maksymilian Prondzynski, Giulia Mearini, Dennis Schade, Sigrid Fuchs, Christiane Neuber, Elisabeth Krämer, Umber Saleem, Mirja L Schulze, Marita L Rodriguez, Thomas Eschenhagen, Arne Hansen
Since the advent of the generation of human induced pluripotent stem cells (hiPSCs), numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and then subsequently assess their ability to recapitulate the properties of adult human cardiomyocytes. However, hiPSC-derived cardiomyocytes (hiPSC-CMs) are often assessed in single-cell assays. A shortcoming of these assays is the limited ability to characterize the physiological parameters of cardiomyocytes, such as contractile force, due to random orientations...
June 2017: Nature Protocols
https://www.readbyqxmd.com/read/28486338/a-comparison-of-load-velocity-and-load-power-relationships-between-well-trained-young-and-middle-aged-males-during-three-popular-resistance-exercises
#9
John F T Fernandes, Kevin L Lamb, Craig Twist
This study examined the load-velocity and load-power relationships among 20 young (age 21.0 ± 1.6 y) and 20 middle-aged (age 42.6 ± 6.7 y) resistance trained males. Participants performed three repetitions of bench press, squat and bent-over-row across a range of loads corresponding to 20 to 80% of one repetition maximum (1RM). Analysis revealed effects (P < 0.05) of group and load x group on barbell velocity for all three exercises, and interaction effects on power for squat and bent-over-row (P < 0...
May 5, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28475549/effects-of-the-inertia-barbell-training-on-lumbar-muscle-t2-relaxation-time
#10
Ming-Yun Sun, Jian-Qiang Lu, Zu-Chang Ma, Jiao-Jiao Lu, Qing Huang, Yi-Ning Sun, Yu Liu
The purpose of this study was to investigate variations in T2 relaxation time in normal human lumbar muscles caused by inertia barbell training. Thirty undergraduate healthy males (mean age=19 ± 1.2 years, weight=72 ± 10.0 kilograms, height=1.78 ± 0.1 meters) were recruited to participate in this study. Subjects were randomly assigned into 2 groups: an inertia barbell training group (IBTG) (n=15) and a normal barbell-training group (NBTG) (n=15). All subjects participated in lumbar flexion and extension muscle strength training for 1 hour per time, 3 times per week for a total of 8 weeks...
April 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28464218/granulocytic-myeloid-derived-suppressor-cells-from-human-cord-blood-modulate-t-helper-cell-response-towards-an-anti-inflammatory-phenotype
#11
Natascha Köstlin, Margit Vogelmann, Bärbel Spring, Julian Schwarz, Judith Feucht, Christoph Härtel, Thorsten W Orlikowsky, Christian F Poets, Christian Gille
Infections are a leading cause of perinatal morbidity and mortality. The outstandingly high susceptibility to infections early in life is mainly attributable to the compromised state of the neonatal immune system. One important difference to the adult immune system is a bias towards T helper (Th) 2-responses in newborns. However, mechanisms regulating neonatal T-cell responses are yet incompletely understood. Granulocytic myeloid-derived suppressor cells (GR-MDSC) are myeloid cells with a granulocytic phenotype that suppress various functions of other immune cells and accumulate under physiological conditions during pregnancy in maternal and foetal blood...
May 2, 2017: Immunology
https://www.readbyqxmd.com/read/28451516/antibiotic-resistance-what-is-so-special-about-multidrug-resistant-gram-negative-bacteria
#12
Martin Exner, Sanjay Bhattacharya, Bärbel Christiansen, Jürgen Gebel, Peter Goroncy-Bermes, Philippe Hartemann, Peter Heeg, Carola Ilschner, Axel Kramer, Elaine Larson, Wolfgang Merkens, Martin Mielke, Peter Oltmanns, Birgit Ross, Manfred Rotter, Ricarda Maria Schmithausen, Hans-Günther Sonntag, Matthias Trautmann
In the past years infections caused by multidrug-resistant Gram-negative bacteria have dramatically increased in all parts of the world. This consensus paper is based on presentations, subsequent discussions and an appraisal of current literature by a panel of international experts invited by the Rudolf Schülke Stiftung, Hamburg. It deals with the epidemiology and the inherent properties of Gram-negative bacteria, elucidating the patterns of the spread of antibiotic resistance, highlighting reservoirs as well as transmission pathways and risk factors for infection, mortality, treatment and prevention options as well as the consequences of their prevalence in livestock...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/28447931/time-trends-in-cardiometabolic-risk-factors-in-adults
#13
Jonas D Finger, Markus A Busch, Yong Du, Christin Heidemann, Hildtraud Knopf, Ronny Kuhnert, Thomas Lampert, Gert B M Mensink, Hannelore K Neuhauser, Angelika Schaffrath Rosario, Christa Scheidt-Nave, Anja Schienkiewitz, Julia Truthmann, Bärbel-Maria Kurth
BACKGROUND: Data from three representative health examination surveys in Germany were analyzed to examine secular trends in the prevalence and magnitude of cardiometabolic risk factors. METHODS: The target variables were the following cardiometabolic risk factors: lack of exercise, smoking, obesity, systolic blood pressure, total cholesterol, serum glucose, self-reported high blood pressure, hyperlipidemia, and diabetes, and the use of antihypertensive, cholesterol-lowering, and antidiabetic drugs...
October 21, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28442418/tlr22-structure-and-expression-characteristic-of-barbel-chub-squaliobarbus-curriculus-provides-insights-into-antiviral-immunity-against-infection-with-grass-carp-reovirus
#14
Rong-Hua Wang, Wei Li, Yu-Ding Fan, Qiao-Lin Liu, Ling-Bing Zeng, Tiao-Yi Xiao
Grass carp reovirus (GCRV) is the most virulent agent to Grass carp, Ctenopharyngodon idella, and causes a severe infectious disease called hemorrhagic disease of grass carp. Generally, barbel chub, Squaliobarbus curriculus, a genetically closely related species to grass carp, exhibits significant resistance against GCRV infection compared to grass carp. To investigate whether the Toll-like receptor 22 (tlr22) has got a vital role against the GCRV infection, the full cDNA sequence of tlr22 from barbel chub (Sctlr22) was cloned by RACE-PCR, and the structure and expression feature were studied...
April 22, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28436441/erratum-cd40-signalling-abrogates-induction-of-ror%C3%AE-t-treg-cells-by-intestinal-cd103-dcs-and-causes-fatal-colitis
#15
Christian Barthels, Ana Ogrinc, Verena Steyer, Stefanie Meier, Ferdinand Simon, Maria Wimmer, Andreas Blutke, Tobias Straub, Ursula Zimber-Strobl, Esther Lutgens, Peggy Marconi, Caspar Ohnmacht, Debora Garzetti, Bärbel Stecher, Thomas Brocker
No abstract text is available yet for this article.
April 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28424870/high-intensity-interval-training-does-not-impair-strength-gains-in-response-to-resistance-training-in-premenopausal-women
#16
Paulo Gentil, Claudio Andre Barbosa de Lira, Suedi Gonçalves Cardoso Filho, Cauê Vazquez La Scala Teixeira, James Steele, James Fisher, Juliana Alves Carneiro, Mário Hebling Campos
PURPOSE: To compare the increases in upper- and lower-body muscle strength in premenopausal women performing resistance training (RT) alone or alongside concurrent high-intensity interval training (CT). METHODS: Sixteen women (26-40 years) were randomly assigned into two groups that performed either RT or CT. Both groups performed the same RT program; however, CT performed additional high-intensity interval training (HIIT) on a bicycle ergometer before RT. The study lasted 8 weeks and the participants were tested for ten repetition maximum (10RM) load in elbow flexion (barbell biceps curl) and knee extension exercises pre- and post-intervention...
April 19, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28423341/glutathione-primes-t-cell-metabolism-for-inflammation
#17
Tak W Mak, Melanie Grusdat, Gordon S Duncan, Catherine Dostert, Yannic Nonnenmacher, Maureen Cox, Carole Binsfeld, Zhenyue Hao, Anne Brüstle, Momoe Itsumi, Christian Jäger, Ying Chen, Olaf Pinkenburg, Bärbel Camara, Markus Ollert, Carsten Bindslev-Jensen, Vasilis Vasiliou, Chiara Gorrini, Philipp A Lang, Michael Lohoff, Isaac S Harris, Karsten Hiller, Dirk Brenner
Activated T cells produce reactive oxygen species (ROS), which trigger the antioxidative glutathione (GSH) response necessary to buffer rising ROS and prevent cellular damage. We report that GSH is essential for T cell effector functions through its regulation of metabolic activity. Conditional gene targeting of the catalytic subunit of glutamate cysteine ligase (Gclc) blocked GSH production specifically in murine T cells. Gclc-deficient T cells initially underwent normal activation but could not meet their increased energy and biosynthetic requirements...
April 18, 2017: Immunity
https://www.readbyqxmd.com/read/28415066/effect-of-barbell-weight-on-the-structure-of-the-flat-bench-press
#18
Henryk Król, Artur Gołaś
Król, H and Gołaś, A. Effect of barbell weight on the structure of the flat bench press. J Strength Cond Res 31(5): 1321-1337, 2017-In this study, we have used the multimodular measuring system SMART. The system consisted of 6 infrared cameras and a wireless module to measure muscle bioelectric activity. In addition, the path of the barbell was measured with a special device called the pantograph. Our study concerns the change in the structure of the flat bench press when the weight of the barbell is increased...
May 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28414787/water-abstraction-affects-abundance-size-structure-and-growth-of-two-threatened-cyprinid-fishes
#19
Roberto Merciai, Carlota Molons-Sierra, Sergi Sabater, Emili García-Berthou
Hydrologic alteration is a major threat to freshwater biota, and particularly fish, in many river courses around the world. We analyzed and compared the effects of water abstraction on two threatened cyprinid fishes of contrasting ecology (the Mediterranean barbel Barbus meridionalis and the Catalan chub Squalius laietanus) in a Mediterranean stream. We compared abundance, size-structure, growth, and condition of both species across perennial and artificially intermittent reaches affected by water abstraction...
2017: PloS One
https://www.readbyqxmd.com/read/28395205/induction-of-erod-and-bfcod-activities-in-tissues-of-barbel-barbus-callensis-from-a-water-reservoir-in-algeria
#20
Safia Habila, Essaid Leghouchi, Ana Valdehita, Azucena Bermejo-Nogales, Smail Khelili, José M Navas
EROD and BFCOD activities were measured in liver and gills of barbel (Barbus callensis, a native North African species) captured at Beni Haroun lake, the most important water reservoir in Algeria. This lake receives wastewater from different origins. Thus, we assessed the level of pollution through the induction of detoxification activities in tissues of barbel, evaluating simultaneously the suitability of this species to be used as a sentinel. Fish were collected between March 2015 and January 2016 at three locations taking into account the pollution sources and accessibility...
August 2017: Ecotoxicology and Environmental Safety
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