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https://www.readbyqxmd.com/read/29238597/effects-of-nine-weeks-isokinetic-training-on-power-golf-kinematics-and-driver-performance-in-pre-elite-golfers
#1
James Parker, Charlie Lagerhem, John Hellström, M Charlotte Olsson
Background: It has previously been shown that isotonic strength training can improve driver performance among golfers, though few studies have investigated effects of strength training on swing kinematics together with driver performance. In this study we investigated whether isokinetic rotational training could improve driver performance and swing kinematic variables amongst elite golfers. Methods: Twenty competitive pre-elite golfers (handicap better than -3.0), 13 men and 7 women, were split into two groups, one group received the isokinetic power training (IK) alongside their normal isotonic pre-season strength-training and the other group continued with their normal isotonic pre-season strength-training regime (IT)...
2017: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29234687/delivery-of-cr2-fh-using-aav-vector-therapy-as-treatment-strategy-in-the-mouse-model-of-choroidal-neovascularization
#2
Gloriane Schnabolk, Nathaniel Parsons, Elisabeth Obert, Balasubramaniam Annamalai, Cecile Nasarre, Stephen Tomlinson, Alfred S Lewin, Bärbel Rohrer
Complement activation plays a significant role in age-related macular degeneration (AMD) pathogenesis, and polymorphisms interfering with factor H (fH) function, a complement alternative pathway (AP) inhibitor, are associated with increased AMD risk. We have previously validated an AP inhibitor, a fusion protein consisting of a complement receptor 2 fragment linked to the inhibitory domain of fH (CR2-fH) as an efficacious treatment for choroidal neovascularization (CNV) when delivered intravenously. Here we tested an alternative approach of AAV-mediated delivery (AAV5-VMD2-CR2-fH or AAV5-VMD2-mCherry) using subretinal delivery in C57BL/6J mice...
June 15, 2018: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/29216270/generation-and-characterization-of-kctd15-mutations-in-zebrafish
#3
Alison Heffer, Gregory D Marquart, Allisan Aquilina-Beck, Nabil Saleem, Harold A Burgess, Igor B Dawid
Potassium channel tetramerization domain containing 15 (Kctd15) was previously found to have a role in early neural crest (NC) patterning, specifically delimiting the region where NC markers are expressed via repression of transcription factor AP-2a and inhibition of Wnt signaling. We used transcription activator-like effector nucleases (TALENs) to generate null mutations in zebrafish kctd15a and kctd15b paralogs to study the in vivo role of Kctd15. We found that while deletions producing frame-shift mutations in each paralog showed no apparent phenotype, kctd15a/b double mutant zebrafish are smaller in size and show several phenotypes including some affecting the NC, such as expansion of the early NC domain, increased pigmentation, and craniofacial defects...
2017: PloS One
https://www.readbyqxmd.com/read/29213057/a-catch-up-illusion-arising-from-a-distance-dependent-perception-bias-in-judging-relative-movement
#4
Tobias Meilinger, Bärbel Garsoffky, Stephan Schwan
The perception of relative target movement from a dynamic observer is an unexamined psychological three body problem. To test the applicability of explanations for two moving bodies participants repeatedly judged the relative movements of two runners chasing each other in video clips displayed on a stationary screen. The chased person always ran at 3 m/s with an observer camera following or leading at 4.5, 3, 1.5 or 0 m/s. We harmonized the chaser speed in an adaptive staircase to determine the point of subjective equal movement speed between runners and observed (i) an underestimation of chaser speed if the runners moved towards the viewer, and (ii) an overestimation of chaser speed if the runners moved away from the viewer, leading to a catch-up illusion in case of equidistant runners...
December 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29212552/validity-and-reliability-of-simple-measurement-device-to-assess-the-velocity-of-the-barbell-during-squats
#5
Silvio Lorenzetti, Thomas Lamparter, Fabian Lüthy
OBJECTIVES: The velocity of a barbell can provide important insights on the performance of athletes during strength training. The aim of this work was to assess the validity and reliably of four simple measurement devices that were compared to 3D motion capture measurements during squatting. Nine participants were assessed when performing 2 × 5 traditional squats with a weight of 70% of the 1 repetition maximum and ballistic squats with a weight of 25 kg. Simultaneously, data was recorded from three linear position transducers (T-FORCE, Tendo Power and GymAware), an accelerometer based system (Myotest) and a 3D motion capture system (Vicon) as the Gold Standard...
December 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29210953/acute-effect-of-citrulline-malate-supplementation-on-upper-body-resistance-exercise-performance-in-recreationally-resistance-trained-men
#6
Adam M Gonzalez, Robert W Spitz, Jamie J Ghigiarelli, Katie M Sell, Gerald T Mangine
To investigate the effect of citrulline malate (CM) supplementation on upper-body resistance exercise performance, twelve recreationally resistance-trained men (21.4±1.6 y; 163.0±46.2 cm; 85.0±12.4 kg) underwent two testing sessions administered in a randomized, double-blind fashion. During each visit, participants were provided either 8 g of CM or a placebo (PL) 40 min prior to beginning a standardized warm-up and initiating a barbell bench press resistance exercise protocol consisting of 5 sets of 15 repetitions at 75% 1RM with 2-minute rest intervals...
November 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29209760/-60-years-of-bundesgesundheitsblatt-a-very-personal-laudatio
#7
EDITORIAL
Bärbel-Maria Kurth
No abstract text is available yet for this article.
December 5, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29183700/attachment-and-eating-a-meta-analytic-review-of-the-relevance-of-attachment-for-unhealthy-and-healthy-eating-behaviors-in-the-general-population
#8
REVIEW
Aida Faber, Laurette Dubé, Bärbel Knäuper
Attachment relationships play an important role in people's wellbeing and affliction with physical and mental illnesses, including eating disorders. Seven reviews from the clinical field have consistently shown that higher attachment insecurity-failure to form trusting and reliable relationships with others-systematically characterized individuals with eating disorders. Nevertheless, to date, it is unclear whether (and if so how) these findings apply to the population at large. Consequently, the objective of the present meta-analysis is to quantify the relationship between attachment and unhealthy and healthy eating in the general population...
November 25, 2017: Appetite
https://www.readbyqxmd.com/read/29181903/a-new-species-of-sisorid-catfish-of-the-genus-exostoma-from-the-salween-drainage-yunnan-china
#9
Xiao-Yong Chen, William J Poly, David Catania, Wan-Sheng Jiang
A new species of the sisorid catfish genus Exostoma Blyth, 1860 was collected from two hill-stream tributaries of the Nujiang (Salween River) drainage in Gaoligong Mountain, south-western Yunnan Province, China from 2003 to 2006 and from two tributaries of the Salween River in Cangyuan County, Lingcang Prefecture, Yunnan Province, China (in 2007) and in Yongde County, Lingcang Prefecture, Yunnan Province, China (in 2015). Exostoma gaoligongensesp. nov. is the 10th species of the genus and is most similar to E...
September 18, 2017: Zoological Research
https://www.readbyqxmd.com/read/29180231/regional-gray-matter-volume-and-structural-network-strength-in-somatic-vs-non-somatic-delusional-disorders
#10
Markus Huber, Robert Christian Wolf, Peter Lepping, Erwin Kirchler, Martin Karner, Fabio Sambataro, Bärbel Herrnberger, Philip R Corlett, Roland W Freudenmann
BACKGROUND: Monothematic delusional disorders are characterized by a single tenacious belief. They provide a great opportunity to study underlying brain structures in the absence of confounding symptoms that accompany delusions in schizophrenia. Delusional beliefs include persecution, jealousy or somatic delusions including infestation. It is unclear whether specific delusional content is associated with distinct neural substrates. METHODS: We used magnetic resonance imaging in patients presenting with somatic vs...
November 24, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29176573/the-retinol-binding-protein-receptor-2-rbpr2-is-required-for-photoreceptor-outer-segment-morphogenesis-and-visual-function-in-zebrafish
#11
Yi Shi, Elisabeth Obert, Bushra Rahman, Bärbel Rohrer, Glenn P Lobo
Vitamin A (all-trans retinol) plays critical roles in mammalian development and vision. Since vitamin A is food-derived, tissue-specific uptake and storage mechanism are needed. In the eye, uptake of RBP4-retinol is mediated by the receptor Stra6, whereas the receptor mediating RBP4 binding and retinol transport into the liver has just recently been discovered. Here we examined the role of zebrafish retinol binding protein receptor 2 (Rbpr2) for RBP4-retinol uptake in developing embryos, using eye development and vision as sensitive readouts...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29176384/the-use-of-mobile-applications-to-collect-data-in-sport-health-and-exercise-science-a-narrative-review
#12
Daniel J Peart, Carlos Balsalobre-Fernández, Matthew P Shaw
Mobile devices are ubiquitous in the population, and most have the capacity to download applications (apps). Some apps have been developed to collect physiological, kinanthropometric and performance data, however the validity and reliability of such data is often unknown. An appraisal of such apps is warranted as mobile apps may offer an alternative method of data collection for practitioners and athletes with money, time and space constraints. This article identifies and critically reviews the commercially available apps that have been tested in the scientific literature, finding evidence to support the measurement of resting heart through photoplethysmograpy, heart rate variability, range of motion, barbell velocity, vertical jump, mechanical variables during running, and distances covered during walking, jogging and running...
November 22, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29172220/-strengthening-public-health-by-strengthening-public-health-research-results-of-the-working-group-7-of-the-forum-future-public-health-berlin-2016
#13
Bärbel Maria Kurth, Tobias Kurth
Public health research is application-oriented, its great potential lies in the interlinking of science and practice, as well as its interdisciplinarity and methodological competence. Public health research is focused on the development and evaluation of measures to protect and improve the health of the population. In doing so, it must make its contribution to tackling the new challenges posed by demographic change, digitalization, new forms of communication and medical progress. By pooling the forces, the public health scientists should actively contribute to policy advice and promoting adequate research funding...
November 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29172217/public-health-gesundheit-f%C3%A3-r-alle
#14
Manfred Wildner, Bärbel-Maria Kurth, Lothar Wieler
No abstract text is available yet for this article.
November 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29153839/asymmetry-between-activation-and-deactivation-during-a-transcriptional-pulse
#15
Lee S S Dunham, Hiroshi Momiji, Claire V Harper, Polly J Downton, Kirsty Hey, Anne McNamara, Karen Featherstone, David G Spiller, David A Rand, Bärbel Finkenstädt, Michael R H White, Julian R E Davis
Transcription in eukaryotic cells occurs in gene-specific bursts or pulses of activity. Recent studies identified a spectrum of transcriptionally active "on-states," interspersed with periods of inactivity, but these "off-states" and the process of transcriptional deactivation are poorly understood. To examine what occurs during deactivation, we investigate the dynamics of switching between variable rates. We measured live single-cell expression of luciferase reporters from human growth hormone or human prolactin promoters in a pituitary cell line...
November 13, 2017: Cell Systems
https://www.readbyqxmd.com/read/29120981/biomechanical-methods-to-quantify-muscle-effort-during-resistance-exercise
#16
Loren Z F Chiu
Muscle hypertrophy and strength adaptations elicited by resistance training dependent on the force exerted by active muscles. As an exercise may use many muscles, determining force for individual muscles or muscle groupings is important to understand the relation between an exercise and these adaptations. Muscle effort - the amount of force or a surrogate measure related to the amount of force exerted during a task - can be quantified using biomechanical methods. The purpose of this review was to summarize the biomechanical methods used to estimate muscle effort in movements, particularly resistance training exercises...
November 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29074645/complete-genome-sequence-of-alteromonas-virus-vb_aspp-h4-4
#17
René Kallies, Bärbel Kiesel, Jakob Zopfi, Lukas Y Wick, Antonis Chatzinotas
Alteromonas virus vB_AspP-H4/4 is a member of the Podoviridae family and was isolated from North Sea water in the 1970s. The complete double-stranded DNA genome has 47,631 bp with 49 predicted genes.
October 26, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29065077/optimizing-half-squat-postactivation-potential-load-in-squat-jump-training-for-eliciting-relative-maximal-power-in-ski-jumpers
#18
Artur Gołaś, Michal Wilk, Petr Stastny, Adam Maszczyk, Katarzyna Pajerska, Adam Zając
Gołaś, A, Wilk, M, Stastny, P, Maszczyk, A, Pajerska, K, and Zając, A. Optimizing half squat postactivation potential load in squat jump training for eliciting relative maximal power in ski jumpers. J Strength Cond Res 31(11): 3010-3017, 2017-Training load manipulation in a single workout session can increase or decrease training effectiveness in terms of athletes' strength or power gains. In ski jumping, the complex training that elicits maximal power gains may take advantage of the postactivation potentiation (PAP) mechanism...
November 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29051233/high-quality-whole-genome-sequences-of-the-oligo-mouse-microbiota-bacterial-community
#19
Debora Garzetti, Sandrine Brugiroux, Boyke Bunk, Rüdiger Pukall, Kathy D McCoy, Andrew J Macpherson, Bärbel Stecher
The Oligo-Mouse-Microbiota (Oligo-MM(12)) is a community of 12 mouse intestinal bacteria to be used for microbiome research in gnotobiotic mice. We present here the high-quality whole genome sequences of the Oligo-MM(12) strains, which were obtained by combining the accuracy of the Illumina platforms with the long reads of the PacBio technology.
October 19, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29046964/differences-in-maxillomandibular-morphology-among-patients-with-mucopolysaccharidoses-i-ii-iii-iv-and-vi-a-retrospective-mri-study
#20
Till Koehne, Anja Köhn, Reinhard E Friedrich, Uwe Kordes, Thorsten Schinke, Nicole Muschol, Bärbel Kahl-Nieke
OBJECTIVE: The aims of this study were to analyze the maxillomandibular morphology of patients with mucopolysaccharidosis (MPS) type I, II, III, IVa and VI and to evaluate the craniofacial effect of hematopoietic stem cell transplantation (HCST) in MPS I. MATERIALS AND METHODS: One hundred head magnetic resonance images were retrospectively analyzed from 41 MPS and 27 control individuals. The width, height and length of the maxilla and mandible were plotted against age and the means of controls, MPS I, MPS II and MPS III were statistically compared...
October 18, 2017: Clinical Oral Investigations
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