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https://www.readbyqxmd.com/read/29346716/neuropeptide-af-induces-piecemeal-degranulation-in-murine-mucosal-mast-cells-a-new-mediator-in-neuro-immune-communication-in-the-intestinal-lamina-propria
#1
Nada Abdellah, Samuel Van Remoortel, Omnia Mohey-Elsaeed, Mohamed-Nabil Mostafa, Yasser A Ahmed, Jean-Pierre Timmermans, Roeland Buckinx
Neuropeptides AF (NPAF), FF (NPFF) and SF (NPSF) are RFamide neuropeptides known to be widely expressed in the mammalian central nervous system, where they fulfill a wide range of functions with pain modulation being the most prominent one. Recent evidence indicates that RFamides act as mediators in mast cell-sensory nerve communications related to allergic disease. Previous work by our group has shown that the expression levels of some members of the Mas-related gene receptor (Mrgpr) family in both enteric neurons and mucosal mast cells change during intestinal inflammation...
January 18, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29346690/using-standardized-patient-assessments-to-evaluate-a-health-literacy-curriculum
#2
Gail S Marion, Jade M Hairston, Stephen W Davis, Julienne K Kirk
BACKGROUND AND OBJECTIVES: Patients' health literacy is a growing concern as patients are expected to perform more self-care. While many US schools implement health literacy in their curricula, time spent on the topic ranges from 0 to 8 hours and is largely didactic. Evaluation of health literacy skills is not well defined. The effectiveness of a health literacy curriculum for third-year medical students was evaluated by two standardized patients assessments (SPAs). METHODS: All third-year medical students complete a required 4-week clerkship in family medicine...
January 2018: Family Medicine
https://www.readbyqxmd.com/read/29346527/progesterone-effects-on-extracellular-vesicles-in-the-sheep-uterus
#3
Gregory W Burns, Kelsey E Brooks, Eleanore V O'Neil, Darren E Hagen, Susanta K Behura, Thomas E Spencer
Progesterone (P4) acts via the endometrium to promote conceptus growth and implantation for pregnancy establishment. Many cells release extracellular vesicles (EVs) that are membrane-bound vesicles of endosomal and plasma membrane origin. In sheep, endometrial-derived EVs were found to traffic to the conceptus trophectoderm. Thus, EVs are hypothesized to be an important mode of intercellular communication by transferring select RNAs, proteins, and lipids between the endometrium and conceptus. Electron microscopy analysis found that the endometrial luminal and glandular epithelia were the primary source of EVs in the uterus of cyclic sheep...
January 16, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29346378/evaluating-the-impact-of-a-virtual-clinic-on-patient-experience-personal-and-provider-costs-of-care-in-urinary-incontinence-a-randomised-controlled-trial
#4
Georgina Jones, Victoria Brennan, Richard Jacques, Hilary Wood, Simon Dixon, Stephen Radley
OBJECTIVE: To evaluate the impact of using a 'virtual clinic' on patient experience and cost in the care of women with urinary incontinence. MATERIALS AND METHODS: Women, aged > 18 years referred to a urogynaecology unit were randomised to either (1) A Standard Clinic or (2) A Virtual Clinic. Both groups completed a validated, web-based interactive, patient-reported outome measure (ePAQ-Pelvic Floor), in advance of their appointment followed by either a telephone consultation (Virtual Clinic) or face-to-face consultation (Standard Care)...
2018: PloS One
https://www.readbyqxmd.com/read/29346314/sustainable-transportation-attitudes-and-health-behavior-change-evaluation-of-a-brief-stage-targeted-video-intervention
#5
Norbert Mundorf, Colleen A Redding, Andrea L Paiva
Promoting physical activity and sustainable transportation is essential in the face of rising health care costs, obesity rates, and other public health threats resulting from lack of physical activity. Targeted communications can encourage distinct population segments to adopt active and sustainable transportation modes. Our work is designed to promote the health, social, and environmental benefits of sustainable/active transportation (ST) using the Transtheoretical Model of Change (TTM), which has been successfully applied to a range of health, and more recently, sustainability behaviors...
January 18, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29346266/the-relationship-between-autism-spectrum-disorder-and-melatonin-during-fetal-development
#6
REVIEW
Yunho Jin, Jeonghyun Choi, Jinyoung Won, Yonggeun Hong
The aim of this review is to clarify the interrelationship between melatonin and autism spectrum disorder (ASD) during fetal development. ASD refers to a diverse range of neurodevelopmental disorders characterized by social deficits, impaired communication, and stereotyped or repetitive behaviors. Melatonin, which is secreted by the pineal gland, has well-established neuroprotective and circadian entraining effects. During pregnancy, the hormone crosses the placenta into the fetal circulation and transmits photoperiodic information to the fetus allowing the establishment of normal sleep patterns and circadian rhythms that are essential for normal neurodevelopment...
January 18, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29346179/avstick-an-intravenous-catheter-insertion-simulator-for-use-with-standardized-patients
#7
Andrew Devenny, Danielle Lord, Joshua Matthews, Julia Tuhacek, Jennifer Vitlip, Mingxu Zhang, Amy C Bucha, Liyun Wang, Jenni M Buckley, Amy Cowperthwait
An overwhelming majority of hospitalized patients undergo intravenous (IV) catheter insertion in order to receive hydration and necessary medication. Current IV insertion training techniques include manikins that are unable to react or give feedback to the trainee. The Avstick® is a realistic training device that can be worn by an actor, allowing a nurse trainee to perform an IV catheter insertion on a live patient without causing the person harm. The purpose of this study is to demonstrate the effectiveness of the Avstick in nursing education to increase nurse-patient communication and trainee self-efficacy...
January 17, 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29346115/mitochondrial-dysfunction-a-key-player-in-the-pathogenesis-of-cardiovascular-diseases-linked-to-air-pollution
#8
REVIEW
Sri Rahavi Boovarahan, Gino A Kurian
Air pollution has become an environmental burden with regard to non-communicable diseases, particularly heart disease. It has been reported that air pollution can accelerate the development of heart failure and atrial fibrillation. Air pollutants encompass various particulate matters (PMs), which change the blood composition and heart rate and eventually leads to cardiac failure by triggering atherosclerotic plaque ruptures or by developing irreversible ischemia. A series of major epidemiological and observational studies have established the noxious effect of air pollutants on cardiovascular diseases (CVD), but the underlying molecular mechanisms of its susceptibility and the pathological disease events remain largely elusive and are predicted to be initiated in the cell organelle...
January 18, 2018: Reviews on Environmental Health
https://www.readbyqxmd.com/read/29345873/patient-education-in-psychopharmacology-and-the-risk-of-nocebo-related-treatment-inefficacy-and-harm
#9
Chittaranjan Andrade
Many studies have shown that educating patients about the potential adverse effects of a drug can increase the chances that those adverse effects will be experienced. Studies have further shown that how such information is communicated can also impact this nocebo risk. Additionally, information provided through patient education can influence treatment efficacy, perhaps by moderating the placebo response. There is therefore a need to optimize the manner in which patients are educated about their medications so that placebo-related benefits are enhanced and nocebo-related harm is minimized...
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345633/impacts-of-an-exercise-program-and-motivational-telephone-counseling-on-health-related-quality-of-life-in-people-with-parkinson-s-disease
#10
JuHee Lee, MoonKi Choi, Yonju Yoo, Sangwoo Ahn, Justin Y Jeon, Ji Young Kim, Ji Yong Byun
PURPOSE: The purpose of this study was to test the effects of group exercise and telephone counseling on physical and psychosocial health in people with Parkinson's disease (PD). DESIGN: This was a quasiexperimental study with a nonequivalent control group. METHODS: This study took place in Seoul, South Korea. Twenty-two and 20 subjects participated in the intervention and comparison groups, respectively. The intervention group performed group exercises twice a week and received motivational telephone counseling every 2 weeks for 12 weeks...
November 14, 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29345625/the-all-optical-modulator-in-dielectric-loaded-waveguide-with-graphene-silicon-heterojunction-structure
#11
Feiying Sun, Liangping Xia, Changbin Nie, Jun Shen, Yixuan Zou, Guiyu Cheng, Hao Wu, Yong Zhang, Dongshan Wei, Shaoyun Yin, Chunlei Du
The all-optical modulators based on graphene show great promise for on-chip optical interconnect. However, the modulation performance of all-optical modulators is usually based on graphene and fiber interaction, limiting their potential in high integration. Based on this point, the all-optical modulator in dielectric-loaded waveguide (DLW) with graphene-silicon heterojunction structure (GSH) is proposed. The DLW raises the waveguide mode which provides a strong light-graphene interaction. And sufficient tuning of graphene Fermi energy beyond the Pauli blocking effect is obtained with the presented GSH structure...
January 18, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29345531/how-tailoring-the-mode-of-information-presentation-influences-younger-and-older-adults-satisfaction-with-health-websites
#12
Minh Hao Nguyen, Ellen M A Smets, Nadine Bol, Eugène F Loos, Julia C M Van Weert
Although older adults are increasingly using online health information, many websites are not senior-friendly, which might lead to user-problems and dissatisfaction among older people. It has been suggested that websites targeted at older adults should take into account age-related abilities and limitations, for example by providing the opportunity to adjust the modality (i.e., "mode") of information presentation based on visual and auditory capabilities. This study investigates the effects of a mode-tailored website, allowing users to self-tailor the mode of information presentation, on younger and older adults' satisfaction with health websites...
January 18, 2018: Journal of Health Communication
https://www.readbyqxmd.com/read/29345483/editorial-journal-article-reporting-standards
#13
Anne E Kazak
In this editorial, the author notes that this issue of American Psychologist features a pair of important articles related to newly updated standards for reporting research in psychology in scientific journals, covering both quantitative (Appelbaum et al., 2018) and qualitative (Levitt et al., 2018) research. The increasing breadth and complexity of research, and the importance of communicating it effectively, requires user-friendly resources that can be applied widely to scientific studies. These two articles are intended to serve that purpose, and to encourage thoroughness and accuracy in research reporting, for psychologists and other scientists in broader academic communities...
January 2018: American Psychologist
https://www.readbyqxmd.com/read/29345256/caregiver-perspectives-on-communication-during-hospitalization-at-an-academic-pediatric-institution-a-qualitative-study
#14
Lauren G Solan, Andrew F Beck, Stephanie A Shardo, Hadley S Sauers-Ford, Jeffrey M Simmons, Samir S Shah, Susan N Sherman
OBJECTIVE: Communication among those involved in a child's care during hospitalization can mitigate or exacerbate family stress and confusion. As part of a broader qualitative study, we present an in-depth understanding of communication issues experienced by families during their child's hospitalization and during the transition to home. METHODS: Focus groups and individual interviews stratified by socioeconomic status included caregivers of children recently discharged from a children's hospital after acute illnesses...
January 18, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29345224/therapy-interventions-for-children-with-neurodisabilities-a-qualitative-scoping-study
#15
Bryony Beresford, Susan Clarke, Jane Maddison
BACKGROUND: Therapy interventions emerged four times in the top 10 research priorities in a James Lind Alliance research prioritisation exercise for children with neurodisabilities (Morris C, Simkiss D, Busk M, Morris M, Allard A, Denness J, et al. Setting research priorities to improve the health of children and young people with neurodisability: a British Academy of Childhood Disability-James Lind Alliance Research Priority Setting Partnership. BMJ Open 2015;5:e006233). The National Institute for Health Research (NIHR) commissioned this study as part of an information-gathering exercise in response to this...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29345217/statistical-analysis-of-human-microarray-data-shows-that-dietary-intervention-with-n-3-fatty-acids-flavonoids-and-resveratrol-enriches-for-immune-response-and-disease-pathways
#16
Alix Warburton, Olga Vasieva, Peter Quinn, James P Stewart, John P Quinn
n-3 Fatty acids, flavonoids and resveratrol are well publicised for their beneficial effects on human health and wellbeing. Identifying common, underlying biological mechanisms targeted by these functional foods would therefore be informative for the public health sector for advising on nutritional health and disease, food and drug product development and consumer interest. The aim of this study was to explore the potential effects of gene expression changes associated with n-3 fatty acids EPA and DHA, flavonoids and resveratrol on modifying biological systems and disease pathways...
January 18, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29345092/-known-unknowns-examining-the-burden-of-neurocognitive-impairment-in-the-end-stage-renal-failure-population
#17
REVIEW
Scott Wilson, Arup Dhar, Peter Tregaskis, Gavin Lambert, David Barton, Rowan Walker
The burden of neurocognitive impairment (NCI) in patients receiving maintenance dialysis represents a spectrum of deficits across multiple cognitive domains which are associated with hospitalisation, reduced quality-of-life, mortality and forced decision-making around dialysis withdrawal. Point prevalence data suggests that dialysis patients manifest NCI at rates 3-5 fold higher than the general population with executive function the most commonly affected cognitive domain. The unique physiology of the renal failure state and maintenance dialysis appears to drive an excess of vascular dementia subtype compared to the general population where classical Alzheimer's disease predominates...
January 18, 2018: Nephrology
https://www.readbyqxmd.com/read/29345084/the-lived-experience-of-autologous-stem-cell-transplanted-patients-post-transplantation-and-before-discharge
#18
Qasem Alnasser, Salahel Deen Abu Kharmah, Manal Attia, Akram Aljafari, Felicia Agyekum, Falak Aftab
AIMS: The aim of this study was to explore the lived experience of the patients post hematopoietic stem cell transplantation (HSCT) and specifically after engraftment and before discharge. BACKGROUND: Patients post stem cell transplantation experience significant changes in all life aspects. Previous studies done by other researchers focused mainly on the post discharge experience, where patients reported their perceptions that has always been affected by the life post transplantation and influenced by their surroundings...
January 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29345021/effects-of-loneliness-on-illness-perception-in-persons-with-a-chronic-disease
#19
Fatma Özkan Tuncay, Tülay Kars Fertelli, Mukadder Mollaoğlu
AIM AND OBJECTIVES: The present study was conducted to determine the effects of loneliness on illness perception in persons with a chronic disease. BACKGROUND: How an illness is perceived not only affects all dimensions of a person's life but also plays an important role in his/her coping with the complications and consequences of the disease. One of the factors that influence the illness perception is loneliness. DESIGN: The study is a descriptive study...
January 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29344773/beyond-content-cultural-perspectives-on-using-the-internet-to-deliver-a-sexual-health-intervention-to-american-indian-youth
#20
Kirsten J Black, Bradley Morse, Nicole Tuitt, CeCe Big Crow, Carly Shangreau, Carol E Kaufman
American Indian and Alaska Native (AIAN) youth are characterized by high rates of pregnancy and risky sexual behavior. Reaching these youth with culturally appropriate interventions is difficult due to geographic dispersion and cultural isolation. Online interventions can provide opportunities for reaching and engaging AIAN youth. However, electronic interventions are also impersonal and this can be culturally incongruous for AIANs and other populations for whom traditional ceremonies, practices and patterns of interpersonal communication are central...
January 17, 2018: Journal of Primary Prevention
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