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https://www.readbyqxmd.com/read/29661643/muscle-ultrasound-elastography-and-mri-in-preschool-children-with-duchenne-muscular-dystrophy
#1
Anna Pichiecchio, Francesco Alessandrino, Chandra Bortolotto, Alessandra Cerica, Cristina Rosti, Maria Vittoria Raciti, Marta Rossi, Angela Berardinelli, Giovanni Baranello, Stefano Bastianello, Fabrizio Calliada
The aim of this study was to determine muscle tissue elasticity, measured with shear-wave elastography, in selected lower limb muscles of patients affected by Duchenne muscular dystrophy (DMD) and to correlate the values obtained with those recorded in healthy children and with muscle magnetic resonance imaging (MRI) data from the same DMD children, specifically the pattern on T1-weighted (w) and short-tau inversion recovery (STIR) sequences. Five preschool DMD children and five age-matched healthy children were studied with shear-wave elastography...
April 13, 2018: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/29661497/postoperative-chemotherapy-for-node-positive-cervical-cancer-results-of-a-multicenter-phase-ii-trial-jgog1067
#2
Maki Matoda, Nobuhiro Takeshima, Hirofumi Michimae, Takashi Iwata, Harushige Yokota, Yutaka Torii, Yorito Yamamoto, Kazuhiro Takehara, Shin Nishio, Hirokuni Takano, Mika Mizuno, Yoshiyuki Takahashi, Yuji Takei, Tetsuya Hasegawa, Mikio Mikami, Takayuki Enomoto, Daisuke Aoki, Toru Sugiyama
OBJECTIVE: This multicenter phase II Japanese Gynecologic Oncology Group study (JGOG1067) was designed to evaluate the efficacy and safety of postoperative chemotherapy in patients with node-positive cervical cancer. METHODS: Patients with stage IB-IIA squamous cervical cancer who underwent radical hysterectomy and were confirmed to have pelvic lymph node metastasis were eligible for this study. The patients postoperatively received irinotecan (CPT-11; 60mg/m2 intravenously on days 1 and 8) and nedaplatin (NDP; 80mg/m2 intravenously on day 1)...
April 13, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29652961/-severe-leg-edema-associated-with-the-use-of-dopaminergic-drugs-in-parkinson-s-disease-report-of-one-case
#3
Marcelo Miranda C, Lorena Hudson A
The main adverse effects of dopaminergic drugs used in Parkinson's disease are hypotension, somnolence, hallucinations and impulse control disorder. Less common is leg edema. We report on a 68-year-old male receiving levodopa and pramipexole consulting for severe leg edema lasting two years, whose etiology was not ascertained with multiple lab tests. This edema subsided substantially when pramipexole was discontinued and the dose of levodopa was increased to treat motor symptoms.
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29628470/a-rare-case-of-rush-progression-of-purulent-pericarditis-by-escherichia-coli-in-a-patient-with-malignant-lymphoma
#4
Shunpei Horii, Hirotaka Yada, Kei Ito, Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Risako Yasuda, Takumi Toya, Takayuki Namba, Nobuyuki Masaki, Takeshi Adachi
Purulent pericarditis is a rare disease in the antibiotic era. The common pathogens of purulent pericarditis are gram-positive species such as Staphylococcus aureus. Streptococcus pneumoniae, Salmonella, Haemophilus, fungal pathogens/tuberculosis can also result in purulent pericarditis. We report an old male case of purulent pericarditis by Escherichia coli. He came to our hospital suffering from leg edema for 3 months. Echocardiography revealed the large amount of pericardial effusion, and he was admitted to test the cause of pericardial effusion without high fever, tachycardia, and shock vital signs...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29619252/lepvax-a-defined-subunit-vaccine-that-provides-effective-pre-exposure-and-post-exposure-prophylaxis-of-m-leprae-infection
#5
Malcolm S Duthie, Maria T Pena, Gigi J Ebenezer, Thomas P Gillis, Rahul Sharma, Kelly Cunningham, Michael Polydefkis, Yumi Maeda, Masahiko Makino, Richard W Truman, Steven G Reed
Sustained elimination of leprosy as a global health concern likely requires a vaccine. The current standard, BCG, confers only partial protection and precipitates paucibacillary (PB) disease in some instances. When injected into mice with the T helper 1 (Th1)-biasing adjuvant formulation Glucopyranosyl Lipid Adjuvant in stable emulsion (GLA-SE), a cocktail of three prioritized antigens (ML2055, ML2380 and ML2028) reduced M. leprae infection levels. Recognition and protective efficacy of a single chimeric fusion protein incorporating these antigens, LEP-F1, was confirmed in similar experiments...
2018: NPJ Vaccines
https://www.readbyqxmd.com/read/29607251/pseudotumor-from-metal-on-metal-total-hip-arthroplasty-causing-unilateral-leg-edema-case-presentation-and-literature-review
#6
REVIEW
Caleb W Grote, Paul C Cowan, David W Anderson, Kimberly J Templeton
Metal-on-metal (MoM) total hip arthroplasty (THA) can be associated with adverse metal reactions, including pseudotumors. This case report describes a 58-year-old female with an MoM THA-related pseudotumor that caused unilateral leg edema from compression of her external iliac vein. After thorough preoperative workup to rule out infection and deep vein thrombosis and consultation with a vascular surgeon, the patient underwent revision THA and excision of her pseudotumor. She had complete resolution of her swelling at 4 years after surgery...
2018: BioResearch Open Access
https://www.readbyqxmd.com/read/29602529/neurosyphilis-as-a-cause-of-transverse-myelitis-in-a-teenage-girl
#7
Karen Kim Jo Yaphockun, Shannon Wai
BACKGROUND: Syphilis is a sexually transmitted infection that was nearly eradicated in 2001 but is now making a resurgence. It has a wide range of clinical manifestations depending on disease stage. Neurosyphilis is an infrequently seen infectious disease with central nervous system involvement that can occur in either early- or late-stage syphilis. The diagnosis of neurosyphilis is challenging, primarily because Treponema pallidum, the infecting organism, cannot be cultured in vitro...
March 27, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29597050/did-fr%C3%A3-d%C3%A3-ric-chopin-die-from-heart-failure
#8
A Perciaccante, P Charlier, C Negri, A Coralli, O Appenzeller, R Bianucci
On October 17, 1849, Poland's greatest composer, Frédéric Chopin (1810-1849) died aged 39. His cause of death remains unknown. An investigation of the documental sources was performed to reconstrcuct the medical history of the artist. Since his earliest years, his life had been dominated by poor health. Recurrent episodes of cough, fever, headaches, lymphadenopathy- a series of symptoms that may be attributed to viral respiratory infections- manifested in his teens. Later in life, he had chest pain, hemoptysis, hematemesis, neuralgia, and arthralgia...
March 26, 2018: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29576951/change-in-skeletal-muscle-stiffness-after-running-competition-is-dependent-on-both-running-distance-and-recovery-time-a-pilot-study
#9
Seyedali Sadeghi, Cassidy Newman, Daniel H Cortes
Long-distance running competitions impose a large amount of mechanical loading and strain leading to muscle edema and delayed onset muscle soreness (DOMS). Damage to various muscle fibers, metabolic impairments and fatigue have been linked to explain how DOMS impairs muscle function. Disruptions of muscle fiber during DOMS exacerbated by exercise have been shown to change muscle mechanical properties. The objective of this study is to quantify changes in mechanical properties of different muscles in the thigh and lower leg as function of running distance and time after competition...
2018: PeerJ
https://www.readbyqxmd.com/read/29570534/neuromuscular-adaptations-to-work-matched-maximal-eccentric-vs-concentric-training
#10
Sumiaki Maeo, Xiyao Shan, Shun Otsuka, Hiroaki Kanehisa, Yasuo Kawakami
It is unclear whether the superiority of eccentric over concentric training on neuromuscular improvements is due to higher torque (mechanical loading) achievable during eccentric contractions or due to resulting greater total work. PURPOSE: To examine neuromuscular adaptations following maximal eccentric versus concentric training matched for total work. METHODS: Twelve males conducted single-joint isokinetic (180°/s) maximal eccentric contractions of the knee extensors in one leg (ECC-leg) and concentric in the other (CON-leg), 6 sets/session (3-5 sets in the initial 1-3 sessions), 2 sessions/week for 10 weeks...
March 22, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29566731/deep-vein-thrombosis-and-pulmonary-embolism-secondary-to-urinary-retention-a-case-report
#11
Tatsushi Kawada, Takashi Yoshioka, Motoo Araki, Hiroyuki Nose, Tadashi Oeda
BACKGROUND: Pulmonary embolism occurs when a blood thrombus forms and travels from a vein in the body to an artery in the lung. Thrombi often develop in one of the deep veins of the legs, thighs, or pelvis, a condition known as deep vein thrombosis. In this report, we describe a rare instance of a patient who developed deep vein thrombosis and pulmonary embolism secondary to urinary retention, and we also review some of the literature. CASE PRESENTATION: A 75-year-old Japanese man visited our hospital with the complaint of lower extremity weakness...
March 23, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29527377/lymphatic-drainage-of-legs-reduces-edema-of-the-arms-in-children-with-lymphedema
#12
Lívia Maria Pereira de Godoy, Paula Pereira de Godoy Capeletto, Maria de Fátima Guerreiro Godoy, Jose Maria Pereira de Godoy
Objective: The aim of the present study is to report on the reduction of edema of lymphedematous arms just by treating the lower limbs. Methods: A 16-year-old girl reported that she has started having right lower limb edema at the age of three. At age 13, she performed a lymphoscintigraphy that confirmed the diagnosis of primary lymphedema of the four limbs. Recently she sought treatment at the Clínica Godoy in São Jose do Rio Preto where she was submitted to intensive treatment for eight hours per day for five days using manual (Godoy & Godoy technique) and mechanical lymphatic therapy (RA Godoy® ) of the lower limbs, cervical lymphatic therapy (cervical stimulation), and the continuous use of a grosgrain stocking...
2018: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29521485/evaluation-of-three-different-devices-to-reduce-stasis-edema-in-poorly-mobile-nursing-home-patients
#13
Jean-Patrick Benigni, Jean-François Uhl, Florence Balet, Pascal Filori, Maxime Chahim
BACKGROUND: Prolonged immobility in the sitting position in the elderly is known to produce venous stasis with leg edema and possible skin changes. Compression stockings are often applied for this clinical problem. There are few experienced nursing staff available to supervise the difficult task of stocking application. METHODS: The authors have researched other effective and simple devices that may be suitable alternatives. This article reports the results of three different devices to reduce leg edema, as measured by reduction in leg volume : an electro- stimulation device, an adjustable compression Velcro® wrap and a short stretch bandage, each tested over a two-hour period...
March 8, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29505002/case-report-of-primary-intestinal-lymphangiectasia-diagnosed-in-an-octogenarian-by-ileal-intubation-and-by-push-enteroscopy-after-missed-diagnosis-by-standard-colonoscopy-and-egd
#14
Mitchell S Cappell, Ahmed Edhi, Mitual Amin
RATIONALE: Primary intestinal lymphangiectasia (PIL) is a rare, presumably congenital lesion that is usually diagnosed in patients < 3 years old, is rarely first diagnosed in adulthood, and when first diagnosed in adulthood typically presents with symptoms for many years. Although PIL is often identified by endoscopic abnormalities, it must be emphasized that the jejunoileum/distal duodenum must be intubated for diagnosis because the lesions are present in these regions. This work demonstrates that 1)-PIL can occur in an octogenarian; 2)-shows that the characteristic endoscopic findings are not found at colonoscopy without terminal ileal intubation; and 3)-may be missed at standard EGD without distal duodenal intubation...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29463493/effect-of-impulsive-compression-treatment-on-postoperative-complications-after-open-peripheral-vascular-revascularization-in-situ-protocol-for-a-randomized-control-trial
#15
Tenna Klit, Marie Dahl, Kim Christian Houlind, Hans Ravn
BACKGROUND: In patients with critical leg ischemia (CLI), the standard operative choice is an in situ bypass to the lower extremity to improve the patients´ prognosis and quality of life. Postoperative complications after surgery occur in 18 % of the patients, prolonging hospitalization and convalescence. The main operative complication is edema. This can be prevented by early mobilization or stimulation of the natural venous pump in the leg. OBJECTIVE: To investigate whether compression therapy with foot pump reduces postoperative edema, facilitates wound healing of the operation wounds, promotes healing of ischemic ulcers, and shortens hospitalization, increasing and improving the patient's subjective quality of life faster...
February 20, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29459568/endovascular-repair-of-an-abdominal-aortic-aneurysm-with-iliac-vein-compression-syndrome
#16
Jun Hayashi, Tetsuro Uchida, Azumi Hamasaki, Atsushi Yamashita, Ken Nakamura, Kimihiro Kobayashi, Mitsuaki Sadahiro
An 84-year-old man with chronic obstructive pulmonary disease (COPD) was referred to our institution for further treatment of severe swelling of the left lower extremity. The left iliac vein was compressed by the abdominal aortic aneurysm and a right common iliac arterial aneurysm measuring 62 mm and 45 mm in diameter and was partially thrombosed. Multiple pulmonary artery embolisms were also noted. Endovascular repair of the abdominal aortic aneurysm and the right common iliac arterial aneurysm was performed because of his respiratory dysfunction...
February 16, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29423155/successful-surgical-treatment-for-huge-retroperitoneal-liposarcoma-involving-the-pancreas-right-kidney-abdominal-aorta-and-inferior-vena-cava
#17
Mariko Tanaka, Toshiyasu Kawahara, Takahiro Nishikoshi, Masahiro Hagiwara, Koji Imai, Kimiharu Hasegawa, Atsuhiro Koya, Naoto Matsuno, Hidehiro Takei, Nobuyoshi Azuma, Hiroyuki Furukawa
Retroperitoneal liposarcoma is a rare neoplasm that often involves other organs and major blood vessels. Complete surgical resection with negative margins is the only potential curative treatment. Here, we report the case of a patient with a large retroperitoneum liposarcoma that was removed by resection of the descending abdominal aorta and infrahepatic inferior vena cava, right nephrectomy and pancreatoduodenectomy following creation of an extra anatomical femoro-femoral crossover bypass after left axillo-left femoral bypass...
November 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29417979/facial-and-bilateral-leg-edema-in-a-patient-using-quetiapine
#18
Ebru Şahan, Meliha Zengin Eroğlu
No abstract text is available yet for this article.
January 2018: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29385792/efficacy-of-micronized-purified-flavonoid-fraction-daflon%C3%A2-on-improving-individual-symptoms-signs-and-quality-of-life-in-patients-with-chronic-venous-disease-a-systematic-review-and-meta-analysis-of-randomized-double-blind-placebo-controlled-trials
#19
Stavros K Kakkos, Andrew N Nicolaides
INTRODUCTION: The use of a venoactive drug is considered an important component of medical treatment of chronic venous disease (CVD), although the efficacy of certain venoactive drugs (VADs) on one or more individual leg symptoms or signs may have not been extensively studied to justify a strong recommendation in guidelines on CVD. The aim of this systematic review and meta-analysis was to study the effectiveness of the micronized purified flavonoid fraction (MPFF, Daflon®) across the spectrum of defined venous symptoms, signs, quality of life (QoL) and treatment assessment by the physician...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29378612/case-report-of-an-unusual-combination-of-purulent-pericarditis-and-false-aneurysm-of-the-ascending-aorta
#20
David Meier, Matthias Kirsch, Salah Dine Qanadli, Olivier Muller, Daniel Fishman, Catalina Trana
BACKGROUND: Purulent pericarditis is an uncommon entity, which is, in very rare cases, associated to infection of the aorta. CASE PRESENTATION: We present the case of a 42-year-old male patient, who was admitted to hospital complaining of tiredness, diarrhea and leg edema. Clinical examination revealed a hypotensive and obviously shocked patient. He was ultimately diagnosed with a rare combination of purulent pericarditis followed by false aneurysm of the ascending aorta...
January 29, 2018: Journal of Cardiothoracic Surgery
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