keyword
https://read.qxmd.com/read/38523822/infected-femoral-artery-pseudoaneurysm-ligation-and-revascularisation-a-case-report
#1
Mohammed Alsagheer Alhewy, Ehab Abd Elmoneim Ghazala, Hassan Gado, Wael Abdo Abdo Abd-Elgawad, Ahmed Atef Khamis
KEY CLINICAL MESSAGE: Although ligating femoral pseudoaneurysm is a safe procedure, some cases require revascularization, and the appropriate treatment should be tailored to the patient. ABSTRACT: In this case report, we highlight the challenge in treating infected femoral artery pseudoaneurysm. The patient, a 37-year-old male intravenous drug abuser, presented to the emergency department with a 2-month history of a progressively growing lump over his right groin...
March 2024: Clinical Case Reports
https://read.qxmd.com/read/38522907/do-not-overlook-dependent-edema
#2
JOURNAL ARTICLE
Yohei Kita, Teppei Koyama, Shinji Machida, Naohiko Imai
No abstract text is available yet for this article.
March 25, 2024: Internal Medicine
https://read.qxmd.com/read/38521678/the-complementary-use-of-muscle-ultrasound-and-mri-in-fshd-early-versus-later-disease-stage-follow-up
#3
JOURNAL ARTICLE
Sanne C C Vincenten, Nicol C Voermans, Donnie Cameron, Baziel G M van Engelen, Nens van Alfen, Karlien Mul
OBJECTIVES: Muscle MRI and ultrasound provide complementary techniques for characterizing muscle changes and tracking disease progression in facioscapulohumeral muscular dystrophy (FSHD). In this cohort study, we provide longitudinal data that compares both imaging modalities head-to-head. METHODS: FSHD patients were assessed at baseline and after five years. Standardized muscle MRI and ultrasound images of five leg muscles were assessed bilaterally. Fat replacement was quantified using MRI fat-fraction (FF) and ultrasound Heckmatt and echogenicity z-scores (EZ-score)...
March 7, 2024: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/38496153/familial-deep-vein-thrombosis-in-a-child-with-antithrombin-iii-deficiency-a-case-report
#4
Shivani Kale, Devika Jadhav, Sampada Tambolkar, Avinash Daru
Deep vein thrombosis (DVT) is caused by a clot (thrombus) formed in the deep veins, usually the legs. The incidence of DVT is notably less prevalent in children than in adults. Here, we present a rare case of DVT in an eight-year-old female child with a significant family history involving the untimely death of the maternal aunt. The child presented with pain and edema in the left lower limb causing immobilization without any obvious cause. The clinical features suggested the possibility of DVT. On further evaluation and radiological investigations, the diagnosis of DVT was confirmed...
February 2024: Curēus
https://read.qxmd.com/read/38482084/a-rare-case-of-brodie-s-abscess-in-the-tibial-diaphysis-masquerading-as-a-vaso-occlusive-sickle-crisis
#5
Shefali Amin, Manish Shrestha, Sahil Amin, Suril Amin, Katherine DiPastina
We present the case of a 19-year-old male with a history of sickle cell anemia who presented to the hospital with worsening lower extremity pain. Given his acute presentation and history of recurrent pain crises, he was admitted to the hospital for management of a suspected acute pain crisis. However, due to continued pain, imaging was obtained which revealed a different diagnosis for the cause of his symptoms. MRI of the left lower leg revealed heterogenous T1 and T2 hyperintense signals within the proximal tibial diaphysis measuring 6...
2024: Journal of Community Hospital Internal Medicine Perspectives
https://read.qxmd.com/read/38465140/eosinophilic-fasciitis-in-a-68-year-old-female
#6
Swetha Chittipolu, Jennifer L Kennard, Ludmila Nahar
Eosinophilic fasciitis (EF) is an uncommon disorder of unknown etiology and poorly understood pathogenesis. In this report, we present a case of a 68-year-old female presented with a rapidly progressing skin tightening condition in her extremities associated with eosinophilia. Four months prior, the patient's initial complaint was skin sensitivity in the legs and forearms. Over time, this led to severe skin tightening, edema, and decreased range of motion. Clinical examination showed tightening of the skin over the anterior forearms, posterior knees, and calves without sclerodactyly or Raynaud's phenomenon...
February 2024: Curēus
https://read.qxmd.com/read/38461135/exogenous-peptide-injection-causing-medical-thigh-compartment-syndrome
#7
JOURNAL ARTICLE
Daniella Lamour, Tony W Bruno, Richard D Shih, Joshua J Solano, Scott M Alter
BACKGROUND: Acute compartment syndrome can be caused by any condition that increases the pressure of an intracompartmental muscular space, resulting in ischemia, which is a limb-threatening emergency. This case report is the first known documented example of an exogenously injected peptide causing compartment syndrome. The use of natural supplements and holistic therapies is on the rise, specifically, peptide injections. It is important to obtain the history of use and routes of administration of these substances...
December 3, 2023: Journal of Emergency Medicine
https://read.qxmd.com/read/38444946/case-report-sustained-complete-remission-with-all-oral-meped-therapy-in-a-patient-with-hodgkin-s-disease-developing-resistance-to-pembrolizumab
#8
K Reuthner, P Aubele, K Menhart, P Rath, D C Harrer, W Herr, J Hahn, M Vogelhuber, D Heudobler, F Lueke, A Reichle, M Grube
Targeted chemotherapy and immune checkpoint inhibitors (ICPi) have expanded the spectrum of therapies for patients with relapsed/refractory (r/r) Hodgkin's disease and significantly improved the proportion of patients with long-term disease control. However, there is no standardized therapeutic option in case of further progression. Recently, we demonstrated that therapy with MEPED (metronomic chemotherapy, everolimus, pioglitazone, etoricoxib, dexamethasone) is highly effective in patients with r/r Hodgkin's disease...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38435190/etiology-of-drug-induced-edema-a-review-of-dihydropyridine-thiazolidinedione-and-other-medications-causing-edema
#9
REVIEW
Evan S Sinnathamby, Bretton T Urban, Robert A Clark, Logan T Roberts, Audrey J De Witt, Danielle M Wenger, Aya Mouhaffel, Olga Willett, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye, Giustino Varrassi
Edema is an accumulation of fluid in the body's tissues that affects millions of Americans yearly. It can affect multiple body parts, for example, the brain or eyes, but often occurs in the periphery, including the feet and legs. Medications, such as dihydropyridine and thiazolidinediones (TZDs), can be the etiology of edema. Edema can develop in association with problems in the vasculature or lymphatic flow. In recent years, a better understanding of these drug-induced mechanisms has been appreciated. Specifically, dihydropyridines can increase hydrostatic pressure and cause selective pre-capillary vessel vasodilation...
February 2024: Curēus
https://read.qxmd.com/read/38424366/mri-t2-mapping-and-shear-wave-elastography-for-identifying-main-pain-generator-in-delayed-onset-muscle-soreness-muscle-or-fascia
#10
JOURNAL ARTICLE
Congcong Fu, Yu Xia, Bingshan Wang, Qiang Zeng, Shinong Pan
INTRODUCTION: The main generator of delayed onset muscle soreness (DOMS) is still unknown. This study aimed to clarify the main generator of DOMS. METHODS: Twelve participants performed eccentric exercise (EE) on lower legs. MRI and ultrasound were used to assess changes of calf muscle and deep fascia before and after EE. These results were then compared to the muscle pain level. RESULTS: Compared to baseline, muscle pain peaked at 24-48 h after EE (downstairs 22...
February 29, 2024: Insights Into Imaging
https://read.qxmd.com/read/38389293/ktws-klippel-trenaunay-weber-syndrome-a-systematic-presentation-of-a-rare-disease
#11
JOURNAL ARTICLE
Ramina Mofarrah, Ramin Mofarrah, Peyman Gooranorimi, Sadaf Emadi, Sueshianth Ghobadi Aski
BACKGROUND: Klippel-Trenaunay-Weber syndrome (KTWS) is a rare disease with a wide range of manifestations. KTWS is characterized by a clinical triad of varicosities of the extremities, cutaneous vascular malformations, and hypertrophy of soft tissues and long bones. The diagnosis is made clinically supplemented with magnetic resonance imaging and computed tomography. AIM: Hereby we aim to highlight the significance of the possible life-threatening first-time presentations associated with the GI system in previously undiagnosed KTWS patients...
February 22, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38383748/magnetic-resonance-imaging-scoring-system-of-the-lower-limbs-in-adult-patients-with-suspected-idiopathic-inflammatory-myopathy
#12
JOURNAL ARTICLE
Laura Ludovica Gramegna, Rita Rinaldi, Laura Maria Beatrice Belotti, Luca Vignatelli, Giovanni Sighinolfi, Valentina Papa, Roberta Costa, Roberto D'Angelo, Claudio Bianchini, Claudio Graziano, Lorenzo Cirignotta, Rita Mule, David Neil Manners, Caterina Tonon, Giovanna Cenacchi, Raffaele Lodi
PURPOSE: We aim to propose a visual quantitative score for muscle edema in lower limb MRI to contribute to the diagnosis of idiopathic inflammatory myopathy (IIM). MATERIAL AND METHODS: We retrospectively evaluated 85 consecutive patients (mean age 57.4 ± 13.9 years; 56.5% female) with suspected IIM (muscle weakness and/or persistent hyper-CPK-emia with/without myalgia) who underwent MRI of lower limbs using T2-weighted fast recovery-fast spin echo images and fat-sat T2 echo planar images...
February 21, 2024: Neurological Sciences
https://read.qxmd.com/read/38382747/compression-therapy-in-dermatology
#13
REVIEW
E Conde Montero, J Dissemond, K Protz Competence
The benefit of lower limb compression therapy is not limited to chronic venous insufficiency, or/and lymphoedema. Thanks to its anti-edema and anti-inflammatory effects, compression therapy is considered a beneficial adjuvant therapy to treat atypical wounds, inflammatory dermatoses, cellulitis, and traumatic wounds in the absence of contraindications. Strict contraindications are limited to severe peripheral arterial disease and decompensated heart failure. The variability of commercially available compression materials and systems such as short-stretch bandages, multi-component systems, zinc oxide bandages, medical adaptive compression systems, ulcer compression stockings, or medical compression stockings facilitates the adaptation of compression therapy to the individual needs of each patient...
February 19, 2024: Actas Dermo-sifiliográficas
https://read.qxmd.com/read/38380168/acupuncture-as-a-complementary-treatment-for-leg-ulcers-in-sickle-cell-disease
#14
Bruno Deltreggia Benites, Heloise Ciol, Sara Teresinha Olalla Saad, Rogerio Oliva Suguitani
BACKGROUND: Sickle-cell diseases (SCD) are a group of hereditary disorders in which a specific mutation in the gene that encodes the hemoglobin ß chain leads to formation of an anomalous hemoglobin molecule (HbS) with high polymerization power. This leads to sickling of erythrocytes in situations of low oxygen tension, such as in microcirculation, resulting in peripheral microvasculature occlusion, chronic hemolysis, inflammation, and damage to several target organs. Malleolar ulcers are among the most-debilitating complications of the disease, as they are associated with significant pain, secondary infections, and social impact due to their aesthetic impairment...
February 1, 2024: Medical Acupuncture
https://read.qxmd.com/read/38365661/miyoshi-myopathy-associated-with-spine-rigidity-and-multiple-contractures-a-case-report
#15
JOURNAL ARTICLE
Sergey N Bardakov, Angelina A Titova, Sergey S Nikitin, Valentin Nikitins, Margarita O Sokolova, Vadim A Tsargush, Elena A Yuhno, Oleg V Vetrovoj, Pierre G Carlier, Yana V Sofronova, Аrtur А Isaev, Roman V Deev
BACKGROUND: Dysferlinopathy is a phenotypically heterogeneous group of hereditary diseases caused by mutations in the DYSF gene. Early contractures are considered rare, and rigid spine syndrome in dysferlinopathy has been previously reported only once. CASE PRESENTATION: We describe a 23-year-old patient with Miyoshi myopathy with a rigid spine and multiple contractures, a rare phenotypic variant. The disease first manifested when the patient was 13 years old, with fatigue of the gastrocnemius muscles and the development of pronounced contractures of the Achilles tendons, flexors of the fingers, and extensors of the toes, followed by the involvement of large joints and the spine...
February 16, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38362584/recovery-of-cardiac-metabolic-function-after-high-dose-prednisolone-in-a-patient-with-inflammatory-myopathy-associated-with-anti-mitochondrial-antibody
#16
Rikuya Tanaka, Shingo Ota, Mana Taniguchi, Jinsoo Koh, Hidefumi Ito, Shinichi Murata, Atsushi Tanaka
UNLABELLED: Myocardial complications in the setting of inflammatory myopathy associated with anti-mitochondrial antibody (AMA) cause various cardiovascular complications. A 64-year-old Japanese man was diagnosed with inflammatory myopathy associated with AMA, and three years after diagnosis, the patient was referred to our hospital with leg edema and dyspnea on exertion. Right ventricular endomyocardial biopsy showed no disease-specific findings, with neither inflammatory cell infiltration nor non-caseating epithelioid cell granuloma, and only mild fibrosis; therefore, we finally diagnosed this patient with cardiac involvement in inflammatory myopathy associated with AMA...
February 2024: Journal of Cardiology Cases
https://read.qxmd.com/read/38362386/ilio-iliac-arteriovenous-fistula-with-may-thurner-syndrome-a-case-report
#17
Tae Hyeon Kim, Jae Woo Yeon, Hyuk Jung Kim, Suk Ki Jang
An ilio-iliac arteriovenous fistula (AVF) is rare. Common factors leading to ilio-iliac AVF include congenital malformations, iatrogeny, and trauma. There is limited documentation in the literature of cases involving ilio-iliac AVF with May-Thurner syndrome. Here, we present a case of an ilio-iliac AVF with May-Thurner syndrome in an 80-year-old male. CT and angiography confirmed extensive ilio-iliac AVF. Successful endovascular procedures for ilio-iliac AVF were performed using several variable-sized coils and 1400-2000 µm gelatin particles...
January 2024: J Korean Soc Radiol
https://read.qxmd.com/read/38353811/edema-related-to-treatment-with-psychotropic-drugs
#18
JOURNAL ARTICLE
Johanna Engel, Beatrice Haack, Oliver Zolk, Timo Greiner, Martin Heinze, Sermin Toto, Johanna Seifert, Stefan Bleich, Catherine Glocker, Renate Grohmann, Michael Schneider, Susanne Stübner
Edema as an adverse drug reaction is a commonly underestimated yet potentially debilitating condition. This study analyzes the incidence of severe psychotropic drug-induced edema (e.g., edema affecting the face, legs, or multiple body parts and lasting for more than 1 week, or in any case necessitating subsequent diuretic use) among psychiatric inpatients. The cases under examination are derived from an observational pharmacovigilance program conducted in German-speaking countries ("Arzneimittelsicherheit in der Psychiatrie", AMSP) from 1993 to 2016...
February 14, 2024: Journal of Neural Transmission
https://read.qxmd.com/read/38343475/tumefactive-multiple-sclerosis
#19
Bünyamin Tosunoğlu, Burcu Gökçe Çokal, Hafize Nalan Güneş, Nilay Kaya, Tahir Kurtuluş Yoldaş
Tumefactive multiple sclerosis (MS) is a subtype of atypical and rare MS that presents with tumor-like lesions in the central nervous system. The lesions may demonstrate a mass effect, edema, with ring enhancement. They can be mistaken for brain tumors or brain abscesses radiologically and clinically. Here we describe an instructive case of a 55-year-old woman with tumefactive MS who presented with occasional numbness in her right arm and leg, headache, thought confusion, and blurred vision for 2 years.
2024: Proceedings of the Baylor University Medical Center
https://read.qxmd.com/read/38322087/re-irradiation-of-a-classic-kaposi-s-sarcoma-using-volumetric-modulated-arc-therapy
#20
Zhe Chen, Steven Daveluy, Geoff Baran, Michael Joiner, Steven Miller
A black male in his 60s diagnosed with classic Kaposi's sarcoma presented with multiple cutaneous nodules and edema of the right foot and lower leg. He was initially treated with alitretinoin 1% topical treatment. However, 16 months after treatment with the alitretinoin, the skin lesions progressed, and he subsequently underwent a course of radiation therapy to a total dose of 2000 centigrays (cGy) in five fractions to his right foot and lower extremities. Approximately 1.5 years after the radiation therapy was completed, multiple new lesions developed on the right foot and distal lower leg...
January 2024: Curēus
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