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May Thurner

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https://www.readbyqxmd.com/read/29924776/-results-of-endovascular-treatment-of-obstructive-lesions-of-veins-of-the-iliofemoral-segment
#1
A V Pokrovskiĭ, I M Ignat'ev, E G Gradusov
OBJECTIVE: The purpose of the study was to assess the immediate and remote results of endovascular treatment of obstructive lesions of the veins of the iliofemoral segment. PATIENTS AND METHODS: We performed balloon angioplasty and stenting for iliofemoral venous thrombosis in a total of 75 patients. Of these, 60 patients were subjected to stenting of post-thrombotic obstructions and 15 patients underwent stenting of non-thrombotic obstructive lesions of the iliac veins (for May-Thurner syndrome - in 11, for extravasal tumour-induced compression and cicatricial stenosis - in 4)...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29909851/may-thurner-syndrome-and-the-risk-of-pulmonary-embolism-in-patients-with-acute-deep-venous-thrombosis
#2
Song Jin, Ziqiang Sun, Xiaoqin Li, Tao Jian, Xing Jin, Sheng Li, Guodong Wang, Chong Ma, Kai Cui, Peng Xu
OBJECTIVE: Pulmonary embolism (PE) is the most common complication of deep venous thrombosis (DVT). May-Thurner syndrome (MTS) is known to increase the risk of DVT, but an association between MTS and PE has not been established. This study investigated an association between MTS and the risk of PE in patients with acute lower extremity DVT. METHODS: Between June 2014 and September 2016, there were 112 patients with DVT at our hospital who underwent venous angiography and computed tomography pulmonary angiography...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29904487/variant-may-thurner-syndrome-compression-of-the-left-common-iliac-vein-by-the-ipsilateral-internal-iliac-artery
#3
Shahrzad Sharafi, Khashayar Farsad
May Thurner syndrome (MTS) is an anatomic variant that can present as acute or chronic deep vein thrombosis. Although it is classically reported in young and middle-aged women, it is also seen in both young and older men. Multiple cases of anatomic variations of MTS have been described. We present an uncommon case of variant MTS, including diagnostic imaging and approach to treatment.
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29874622/collective-cell-behavior-in-mechanosensing-of-substrate-thickness
#4
Camelia G Tusan, Yu-Hin Man, Hoda Zarkoob, David A Johnston, Orestis G Andriotis, Philipp J Thurner, Shoufeng Yang, Edward A Sander, Eileen Gentleman, Bram G Sengers, Nicholas D Evans
Extracellular matrix stiffness has a profound effect on the behavior of many cell types. Adherent cells apply contractile forces to the material on which they adhere and sense the resistance of the material to deformation-its stiffness. This is dependent on both the elastic modulus and the thickness of the material, with the corollary that single cells are able to sense underlying stiff materials through soft hydrogel materials at low (<10 μm) thicknesses. Here, we hypothesized that cohesive colonies of cells exert more force and create more hydrogel deformation than single cells, therefore enabling them to mechanosense more deeply into underlying materials than single cells...
June 5, 2018: Biophysical Journal
https://www.readbyqxmd.com/read/29793013/may-thurner-syndrome-presenting-as-acute-unexplained-dvt
#5
Zulfiqar Qutrio Baloch, Muhammad Hussain, Muhammad Ayyaz, Nishant Dagli, Shabber Agha Abbas
May-Thurner syndrome (MTS) is a rare cause of deep venous thrombosis (DVT) and occurs due to an anatomic anomaly which produces chronic compression of the left common iliac vein by the overlying right common iliac artery when it passes between the right common iliac artery and the spine. Prolonged compression on the vein potentiates thrombus formation by impairing the intima and by leading to the development of membranes within the lumen that may decrease and/or block venous flow. In this case presentation, we elaborate upon a case of a 43-year-old woman who presented with worsening left leg swelling and pain...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29779990/may-thurner-syndrome-in-operative-ankle-fracture-dislocations-a-case-report
#6
Joshua L Moore, Kelly M Pirozzi, Corine Creech, Benjamin Marder
May-Thurner syndrome (MTS) is a rare condition in which patients develop iliofemoral deep venous thrombosis owing to an anatomic variant in which the right common iliac artery overlies and compresses the left common iliac vein against the lumbar spine. Data regarding lower extremity trauma in patients with previously diagnosed MTS are rare. We discuss the operative approach for ankle trauma occurring 3 weeks after endovascular surgery for the treatment of MTS.
May 17, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29777852/is-may-thurner-syndrome-combined-with-left-iliac-arteriovenous-fistularare-or-neglected-cases-report-and-literature-review
#7
Che Haijie, Li Lubin, Song Fubo, Yang Mu
May-Thurner Syndrome (MTS) is a condition in which the left common iliac vein is compressed by the right common iliac artery, which may cause swelling, pain or deep venous thrombosis of the left lower extremity1 .Post-thrombotic syndrome, non-thrombotic chronic venous insufficiency and recurrence after venous thrombosis are also possible complications. Although MTS combined with left iliac arteriovenous fistula (AVF) is rarely reported, we treated three such cases in the past year.
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29772369/sciatic-neuralgia-caused-by-may-thurner-syndrome-case-report
#8
Kazuaki Yamamoto, Gakuji Gondo, Hidemitsu Ogino, Tsuyoshi Watanabe, Masahiko Tanaka, Satoshi Tanaka, Taisuke Kawasaki
BACKGROUND: Sciatic neuralgia (SN) is a type of pain commonly associated with lumbosacral radiculopathy. May-Thurner syndrome (MTS) is a disease characterized by venous congestion in the left common iliac vein (LCIV) due to right common iliac artery compression. In this report, the authors describe a case of MTS with SN as the first presenting symptom. CASE DESCRIPTION: A 53-year-old man gradually developed left SN; however, radiological examination showed no causal findings...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29753382/may-thurner-syndrome
#9
Yub Raj Sedhai, Reshma Golamari, Aliaksei Salei, Joseph Alukal, Soney Basnyat, Sunil Pathak, Santosh Timalsina, Subtain Zia, Suraj Malhan, Priyanka T Bhatacharya
This single-center, retrospective review identified 6 patients (n = 6, 100% female) treated by endovascular therapy for May-Thurner syndrome from June 2013 to September 2015. Patients consisted of 3 African American, 2 Caucasian and 1 Asian; mean age was 53.50 ± 8.31 years, range: 39-63 years. Clinical presentations consisted of left lower extremity deep vein thrombosis in 4, left lower extremity deep vein thrombosis with pulmonary embolism in 1 and pulmonary embolism with left common iliac vein thrombosis in 1 patient...
May 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29730371/acute-iliac-vein-thrombosis-secondary-to-exacerbation-of-may-thurner-syndrome-by-overriding-arterial-crossover-sheath
#10
Wai Kin Chi, Bryan P Yan
No abstract text is available yet for this article.
April 27, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29706657/hypertonicity-enforced-bcl-2-addiction-unleashes-the-cytotoxic-potential-of-death-receptors
#11
Simon Sirtl, Gertrud Knoll, Dieu Thuy Trinh, Isabell Lang, Daniela Siegmund, Stefanie Gross, Beatrice Schuler-Thurner, Patrick Neubert, Jonathan Jantsch, Harald Wajant, Martin Ehrenschwender
Attempts to exploit the cytotoxic activity of death receptors (DR) for treating cancer have thus far been disappointing. DR activation in most malignant cells fails to trigger cell death and may even promote tumor growth by activating cell death-independent DR-associated signaling pathways. Overcoming apoptosis resistance is consequently a prerequisite for successful clinical exploitation of DR stimulation. Here we show that hyperosmotic stress in the tumor microenvironment unleashes the deadly potential of DRs by enforcing BCL-2 addiction of cancer cells...
April 30, 2018: Oncogene
https://www.readbyqxmd.com/read/29705226/contralateral-deep-vein-thrombosis-after-iliac-vein-stent-placement-in-patients-with-may-thurner-syndrome
#12
Trong Binh Le, Taeg Ki Lee, Keun-Myoung Park, Yong Sun Jeon, Kee Chun Hong, Soon Gu Cho
PURPOSE: To investigate the incidence and potential causes of contralateral deep vein thrombosis (DVT) after common iliac vein (CIV) stent placement in patients with May-Thurner syndrome (MTS). MATERIALS AND METHODS: Data of 111 patients (women: 73%) who had CIV stent implantation for symptomatic MTS at a single center were retrospectively analyzed. Mean patient age was 63.1 ± 15.2 years. Median follow-up was 36 months (range, 1-142 months). Stent location was determined by venogram and classified as extended to the inferior vena cava (IVC), covered the confluence, or confined to the iliac vein...
June 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29701417/surgical-thrombectomy-fibrinolysis-angioplasty-and-stenting-a-combined-approach-for-treatment-of-a-may-thurner-syndrome-presenting-as-phlegmasia-cerulea-dolens
#13
Carlos Veiga, João Gonçalves, Pedro Sousa, Carolina Vaz, Ivone Silva, Pedro Sá-Pinto, Rui Almeida
INTRODUCTION: Phlegmasia cerulea dolens (PCD) is a rare complication of deep venous thrombosis (DVT). Massive ileo-femoral DVT is usually the cause and prompt treatment is mandatory as it represents a medical emergency. Reported amputation rates range from 12% to 25% and mortality ranges from 25% to 40%. Limb ischemia results from obstruction to arterial inflow secondary to extreme levels of venous hypertension. Primary treatment goal is restoration of venous outflow and can be achieved by endovascular or surgical techniques...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29627780/double-venous-compression-due-to-duplicated-inferior-vena-cava-induced-right-common-iliac-vein-thrombosis
#14
Yuichi Mukai, Shuhei Nozawa, Toshiro Suzuki
Venous compression syndromes are caused by extrinsic venous compression of anatomical structures, such as the adjacent arteries and bones. Chronic venous compression and pulsative vibratory arterial pressure accelerate the development of deep vein thrombosis. Herein, we report the first case of double venous compressions due to a duplicated inferior vena cava-induced right-sided common iliac vein thrombosis. The thrombus was induced by left-sided inferior vena cava entrapment and right-sided common iliac vein compression, resembling nutcracker syndrome and May-Thurner syndrome, respectively...
April 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29529373/collagen-fibrils-nature-s-highly-tunable-nonlinear-springs
#15
Orestis G Andriotis, Sylvia Desissaire, Philipp J Thurner
Tissue hydration is well known to influence tissue mechanics and can be tuned via osmotic pressure. Collagen fibrils are nature's nanoscale building blocks to achieve biomechanical function in a broad range of biological tissues and across many species. Intrafibrillar covalent cross-links have long been thought to play a pivotal role in collagen fibril elasticity, but predominantly at large, far from physiological, strains. Performing nanotensile experiments of collagen fibrils at varying hydration levels by adjusting osmotic pressure in situ during atomic force microscopy experiments, we show the power the intrafibrillar noncovalent interactions have for defining collagen fibril tensile elasticity at low fibril strains...
April 24, 2018: ACS Nano
https://www.readbyqxmd.com/read/29487103/should-catheter-directed-thrombolysis-be-the-standard-of-care-for-pregnancy-related-iliofemoral-deep-vein-thrombosis
#16
Tze Hung Siah, Alexander Chapman
A 33-year-old, 8-week pregnant woman presented with mottling, pain and swelling of her left leg. Ultrasound Doppler scan revealed a large left iliofemoral deep vein thrombosis and the patient was diagnosed with phlegmasia cerulea dolens. After 24 hours of treatment with unfractionated heparin, there were minimal improvements in her symptoms. Catheter-directed thrombolysis was performed, following multidisciplinary consultation with the patient. An underlying May-Thurner lesion was identified and successfully stented...
February 27, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29481922/recurrent-iliofemoral-venous-thrombosis-in-the-setting-of-may-thurner-syndrome-as-the-presenting-symptom-of-behcet-s-disease
#17
Sameer Lakha, Chien Yi Maximilian Png, Kevin Chun, Windsor Ting
BACKGROUND: Vascular manifestations including pulmonary artery aneurysms and venous thrombosis are seen in up to 14% of patients with Behcet's disease. We report a patient who had recurrent deep vein thrombosis (DVT) as the presenting symptom of Behcet's Disease. METHODS: A 19-year-old male who presented with acute iliofemoral DVT, confirmed by intravascular ultrasound (IVUS) and venogram. May-Thurner syndrome was also observed. Repeated catheter-based pharmacomechanical thrombolysis, thrombectomy, and subsequent iliac vein stenting were performed...
May 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29435334/may-thurner-syndrome-revealed-by-left-calf-venous-claudication-during-running-a-case-report
#18
Samuel Béliard, Damien Feuvrier, Emilie Ducroux, Lucie Salomon du Mont
No abstract text is available yet for this article.
2018: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29399529/re-intervention-for-occluded-iliac-vein-stents
#19
REVIEW
Stacey Black, Amy Janicek, M Grace Knuttinen
Iliac vein stenting has become more frequent with improved diagnostic capabilities of intra-vascular ultrasound (IVUS) for recognizing May-Thurner syndrome, chronic venous insufficiency (CVI) and thrombus. In this manuscript, we discuss the reasons for initial stenting, with long-term outcomes and some of the associated pitfalls. The best techniques for re-intervention when iliac stents become occluded will also be discussed.
December 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29399519/may-thurner-diagnosis-and-endovascular-management
#20
REVIEW
M-Grace Knuttinen, Sailendra Naidu, Rahmi Oklu, Scott Kriegshauser, William Eversman, Lisa Rotellini, Patricia E Thorpe
Common left iliac vein compression, otherwise known as May-Thurner (MT), is an anatomical risk factor for lower extremity deep vein thrombosis (DVT). MT refers to chronic compression of the left iliac vein against the lumbar spine by the overlying right common iliac artery. The compression may be asymptomatic. The syndrome is a clinical spectrum of physical findings and history plus the lesion. It is characterized by the varying degrees of venous hypertension. This can be non-thrombotic, combined with acute DVT or post-thrombotic...
December 2017: Cardiovascular Diagnosis and Therapy
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