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Cervical spinal cord injury

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https://www.readbyqxmd.com/read/28918261/rat-motor-neurons-caudal-to-a-rubrospinal-tract-rst-transection-remain-viable
#1
Brandon M Wild, Rahul Mohan, Renée Morris
In the rat, the rubrospinal tract (RST) is a descending motor pathway involved in the production of skilled reaching movement. The RST originates in the red nucleus in the midbrain and runs down the spinal cord in the lateral-most aspect of the dorsolateral funiculus (DLF). The RST makes monosynaptic contact with interneurons within the intermediate laminae of the cord, however a contingent of RST axons constitutes direct supraspinal input for spinal cord motor neurons. The current study investigated the effects of unilateral RST transection at cervical levels C3-4 on the population of motor neurons in both spinal segments C5-6 and L2-3...
September 13, 2017: Neuroscience
https://www.readbyqxmd.com/read/28913694/emergency-neurological-life-support-traumatic-spine-injury
#2
Deborah M Stein, William A Knight
Traumatic spine injuries (TSIs) carry significantly high risks of morbidity, mortality, and exorbitant health care costs from associated medical needs following injury. For these reasons, TSI was chosen as an ENLS protocol. This article offers a comprehensive review on the management of spinal column injuries using the best available evidence. Though the review focuses primarily on cervical spinal column injuries, thoracolumbar injuries are briefly discussed as well. The initial emergency department (ED) clinical evaluation of possible spinal fractures and cord injuries, along with the definitive early management of confirmed injuries, are also covered...
September 14, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28904564/the-role-of-pre-reduction-mri-in-the-management-of-complex-cervical-spine-fracture-dislocations-an-ongoing-controversy
#3
Sergiu Botolin, Todd F VanderHeiden, Ernest E Moore, Herbert Fried, Philip F Stahel
BACKGROUND: Cervical spine fracture-dislocations in neurologically intact patients represent a surgical challenge due to the risk of inflicting iatrogenic spinal cord compression by closed reduction maneuvers. The use of MRI for early advanced imaging in these injuries remains controversially debated. CASE PRESENTATION: A 54-year old man sustained a fall over the handlebars of his racing bicycle. The helmeted patient sustained a fall on his head which resulted in a hyperflexion injury of the neck...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28903771/novel-spatiotemporal-analysis-of-gait-changes-in-body-weight-supported-treadmill-trained-rats-following-cervical-spinal-cord-injury
#4
Nathan D Neckel
BACKGROUND: Common gait measures such as stride length, cycle time, and step height are not independent variables, but different aspects of the same multidimensional step. This complicates comparisons between experimental groups. Here we present a novel multidimensional gait analysis method and use this method to assess the ability of body weight supported treadmill training (BWSTT) to improve rodent stepping after spinal cord injury (SCI). METHODS: In lieu of reducing a step to a collection of gait measures and comparing the means of several of these, we developed a multidimensional analysis technique that compares the step as a whole...
September 13, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28902102/post-traumatic-spinal-hygroma-causing-cord-compression-in-type-iii-odontoid-fracture-with-vertical-atlantoaxial-instability
#5
Salvatore Russo, Antonio Belli, Andy Eynon, Ali Nader-Sepahi
STUDY DESIGN: Case report. OBJECTIVE: To report the first case in the literature of a traumatic cervical spine subdural cerebrospinal fluid (CSF) collection (hygroma) under tension causing cord compression. We suggest etiopathogenesis and modality of treatment. SUMMARY OF BACKGROUND DATA: Hygromas are subdural cranial CSF collection. A literature review showed no previous published case of post-traumatic spinal hygroma. This was a potential life-threatening sequelae of a high cervical injury that warranted early diagnosis and emergency treatment...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28899046/human-neural-stem-cell-transplantation-in-chronic-cervical-spinal-cord-injury-functional-outcomes-at-12-months-in-a-phase-ii-clinical-trial
#6
George M Ghobrial, Kim D Anderson, Marine Dididze, Jasmine Martinez-Barrizonte, Gabriel H Sunn, Katie L Gant, Allan D Levi
No abstract text is available yet for this article.
September 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28895577/a-study-of-predictors-for-hyponatraemia-in-patients-with-cervical-spinal-cord-injury
#7
P W Song, F L Dong, C C Feng, Y N Shen, Y Wang, R J Zhang, P Ge, C L Shen
STUDY DESIGN: A retrospective study. OBJECTIVES: The objectives of the study were to investigate the predictors for hyponatraemia in patients with cervical spinal cord injuries (CSCIs) and to define the relationship between magnetic resonance imaging (MRI) scans and hyponatraemia. SETTING: The study was carried out at The First Affiliated Hospital of Anhui Medical University. METHODS: A total of 292 patients with CSCIs were retrospectively reviewed to determine the predictors of hyponatraemia...
September 12, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28895574/generating-rasch-based-activity-of-daily-living-measures-from-the-spinal-cord-injury-longitudinal-aging-study
#8
C-Y Li, C A Velozo, I Hong, C Li, J C Newman, J S Krause
STUDY DESIGN: Retrospective Longitudinal Study. OBJECTIVES: (1) To determine whether the Spinal Cord Injury Activities of Daily Living (SCI_ADL) measure shows adequate item-level and precision psychometrics; (2) to investigate whether the SCI_ADL measure effectively detects ADL changes across time; (3) to describe self-care task(s) participants can and cannot do across time. SETTING: Two Midwestern hospitals and 1 Southeastern specialty hospital in 1993...
September 12, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28893422/the-brain-is-needed-to-cure-spinal-cord-injury
#9
REVIEW
Tadashi Isa
Damage to corticospinal fibers in the cervical spinal cord is known to impair dexterous hand movements. However, accumulating evidence has shown that precision grip can recover considerably through rehabilitative training. Recent multidisciplinary studies have revealed that, at the spinal level, this recovery is possible due to an indirect neural pathway through propriospinal neurons (PNs), which relay cortical commands to hand motoneurons. Although this indirect spinal pathway is heavily involved in recovery, its role is dwarfed by a simultaneous large-scale network reorganization spanning motor-related cortices and mesolimbic structures...
September 8, 2017: Trends in Neurosciences
https://www.readbyqxmd.com/read/28890805/outcome-after-post-acute-spinal-cord-specific-rehabilitation-a-german-single-center-study
#10
Matthias Ponfick
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The objective of this study was to analyze single center outcome measures of spinal cord injury (SCI)-specific rehabilitation (SCISR) in Germany. SETTING: The study was conducted at an SCI specialized rehabilitation center. METHODS: Nonparametric tests for outcome description such as SCIM and length of stay. Logistic regression for outcome prediction was used. RESULTS: One hundred and sixty patients (113 men, 47 women) with a mean age of 64...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28885343/risk-factors-and-the-surgery-affection-of-respiratory-complication-and-its-mortality-after-acute-traumatic-cervical-spinal-cord-injury
#11
Xiao-Xiong Yang, Zong-Qiang Huang, Zhong-Hai Li, Dong-Feng Ren, Jia-Guang Tang
The aim of this study is to estimate the risk factors of both respiratory complication (RC) and mortality after acute traumatic cervical spinal cord injury (TCSCI). Between July 2005 and July 2015, in 181 patients (142 males and 39 females; mean age 41.0 years) with acute TCSCI, we compared the difference and odds ratio in RC group (n = 73) with that of non-RC group (n = 108), and also death group (n = 15) and survival group (n = 166). We collected injury-related information after half a year of injury, which is as follows: the causes of injury, time of surgery, ICU (intensive care unit) days, ventilator days, ASIA (American Spinal Injury Association) classification, neurological injury, CIPS (Clinical Pulmonary Infection Score), and BMI (body mass index)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28884108/characteristics-and-clinical-aspects-of-patients-with-spinal-cord-injury-undergoing-surgery
#12
João Simão de Melo-Neto, Lara Eduarda Leite Vidotto, Fabiana de Campos Gomes, Dionei Freitas de Morais, Waldir Antonio Tognola
OBJECTIVE: To identify the characteristics of patients with spinal cord injury (SCI) undergoing surgery. METHODS: Previously, 321 patients with SCI were selected. Clinical and socio-demographic variables were collected. RESULTS: A total of 211 patients were submitted to surgery. Fall and injuries in the upper cervical and lumbosacral regions were associated with conservative treatment. Patients with lesions in the lower cervical spine, worse neurological status, and unstable injuries were associated with surgery...
June 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28879883/the-role-of-diffusion-tensor-imaging-in-spinal-pathology-a-review
#13
REVIEW
Dan C Li, James G Malcolm, Rima S Rindler, Griffin R Baum, Avinash Rao, Shekar N Khurpad, Faiz U Ahmad
Diffusion tensor imaging (DTI) allows for noninvasive, in vivo visualization of white matter fiber tracts in the central nervous system by measuring the diffusion of water molecules. It provides both quantitative and qualitative (i.e., tractography) means to describe a region-of-interest. While protocols for the use of DTI are better established in the brain, the efficacy and potential applications of DTI in spinal cord pathology are less understood. In this review, we examine the current literature regarding the use of DTI in the spinal cord pathology, and in particular its diagnostic and prognostic value in traumatic injury, spinal tumors, cervical myelopathies, amyotrophic lateral sclerosis, and multiple sclerosis...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28875929/pediatric-cervical-spine-injuries-with-neurological-deficits-treatment-options-and-potential-for-recovery
#14
Belal Elnady, Essam El-Morshidy, Mohamed El-Meshtawi, Ahmed Shawky
PURPOSE: The purpose of the present study was to highlight the challenges in managing cervical spine injuries in children with neurological deficits. INTRODUCTION: Cervical spine injuries in children are relatively rare. Pattern, severity, and level of these injuries are age dependent. Neurological deficits in young children are uncommon and usually have a good potential for recovery. PATIENTS AND METHODS: This report includes four cases with pediatric cervical spine injuries with variable degrees of spinal cord injuries and neurological deficits...
2017: SICOT-J
https://www.readbyqxmd.com/read/28875740/smart-device-environmental-control-systems-experiences-of-people-with-cervical-spinal-cord-injuries
#15
Bethany Hooper, Michele Verdonck, Delena Amsters, Michelle Myburg, Emily Allan
BACKGROUND: Environmental control systems (ECS) are devices that enable people with severe physical limitations to independently control household appliances. Recent advancements in the area of environmental control technology have led to the development of ECS that can be controlled through mainstream smart-devices. There is limited research on ECS within Australia and no known research addressing smart-device ECS. The current study sought to explore users' experiences with smart-device ECS within Australia...
September 6, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28874099/the-health-economics-of-the-spinal-cord-injury-or-disease-among-veterans-of-war-a-systematic-review
#16
Julio C Furlan, Sivakumar Gulasingam, B Catharine Craven
Context Information on health-care utilization and the economic burden of disease are essential to understanding service demands, service accessibility, and practice patterns. This information may also be used to enhance the quality of care through altered resource allocation. Thus, a systematic review of literature on the economic impact of caring for SCI/D veterans would be of great value. Objective To systematically review and critically appraise the literature on the economics of the management of veterans with SCI/D...
September 6, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28872149/correlation-between-diffusion-tensor-imaging-parameters-and-clinical-assessments-in-patients-with-cervical-spondylotic-myelopathy-with-and-without-high-signal-intensity
#17
Y Liu, C Kong, L Cui, X Yuan, P Zhao, Y Zhang, Y Guan, X Chen
STUDY DESIGN: A cross-sectional observational study. OBJECTIVES: The aim of this study is to compare the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) between patients with cervical spondylotic myelopathy (CSM) with and without high T2-weighted signal intensity, and to correlate each parameter with clinical assessments. SETTING: CSM is a common cause of spinal cord dysfunction. The significance of T2 high signal intensity in the prognosis of CSM remains controversial...
September 5, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28872148/incidence-of-traumatic-spinal-cord-injury-in-italy-during-2013-2014-a-population-based-study
#18
S Ferro, L Cecconi, J Bonavita, M C Pagliacci, A Biggeri, M Franceschini
STUDY DESIGN: Observational prospective population-based incidence study. OBJECTIVES: The main objective of this study was to assess the incidence of traumatic spinal cord injuries (TSCIs) and incidence rates, in order to provide estimates by age, gender, characteristics and cause. SETTING: This study was conducted at acute-care spinal cord injury (SCI) hospitals and SCI centers from 11 Italian regions, between 1 October 2013 and 30 September 2014...
September 5, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28871033/reticulospinal-contributions-to-gross-hand-function-after-human-spinal-cord-injury
#19
Stuart N Baker, Monica A Perez
Multiple descending motor pathways likely contribute to the recovery of hand motor function following spinal cord injury (SCI). Reticulospinal neurons project to spinal motor neurons controlling hand muscles and extensively sprout into gray matter structures after SCI; therefore, it has been proposed that the reticulospinal tract is one of the descending motor pathways involved in recovery of hand function after injury. To test this hypothesis, we examined the StartReact response, an involuntary release of a planned movement via a startling stimulus that engages the reticulospinal tract, by measuring reaction times from electromyographic activity in an intrinsic finger muscle during three motor tasks requiring different degrees of hand dexterity: index finger abduction, a precision grip, and a power grip...
September 4, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28870432/the-pseudo-ct-myelogram-sign-an-aid-to-the-diagnosis-of-underlying-brain-stem-and-spinal-cord-trauma-in-the-presence-of-major-craniocervical-region-injury-on-post-mortem-ct
#20
F Bolster, Z Ali, B Daly
AIM: To document the detection of underlying low-attenuation spinal cord or brain stem injuries in the presence of the "pseudo-CT myelogram sign" (PCMS) on post-mortem computed tomography (PMCT). MATERIALS AND METHODS: The PCMS was identified on PMCT in 20 decedents (11 male, nine female; age 3-83 years, mean age 35.3 years) following fatal blunt trauma at a single forensic centre. Osseous and ligamentous craniocervical region injuries and brain stem or spinal cord trauma detectable on PMCT were recorded...
September 1, 2017: Clinical Radiology
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