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ambulatory ECG monitoring

Evan D Muse, Nathan E Wineinger, Emily G Spencer, Melissa Peters, Riley Henderson, Yunyue Zhang, Paddy M Barrett, Steven P Rivera, Jay G Wohlgemuth, James J Devlin, Dov Shiffman, Eric J Topol
BACKGROUND: Atrial fibrillation (AF) is the most commonly encountered arrhythmia and is associated with an elevated risk of stroke. Improving the identification of patients with the highest risk for AF to enable appropriate surveillance and treatment, if necessary, is critical to reducing AF-associated morbidity and mortality. Multiple common single nucleotide polymorphisms (SNPs) are unequivocally associated with the lifetime risk of AF. In the current study we aimed to prospectively validate an AF genetic risk score (GRS) in previously undiagnosed patients at risk for AF...
March 2018: PLoS Medicine
Salma I Patel, Michael J Ackerman, Fadi E Shamoun, Jeffrey B Geske, Steve R Ommen, William T Love, Stephen S Cha, Johan M Bos, Steven J Lester
INTRODUCTION: Risk assessment for sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) remains complex. The goal of this study was to assess electrocardiogram (ECG)-derived risk factors on SCD in a large HCM population Methods: Retrospective review of adults with HCM evaluated at Mayo Clinic, Rochester, MN from 1 December 2002 to 31 December 2012 was performed. Data inclusive of ECG and 24-hour ambulatory Holter monitor were assessed. SCD events were documented by ventricular fibrillation (VF) noted on implantable cardioverter defibrillator (ICD), or appropriate VT or VF-terminating ICD shock...
March 7, 2018: Acta Cardiologica
Heenam Yoon, Su Hwan Hwang, Sang Ho Choi, Jae-Won Choi, Yu Jin Lee, Do-Un Jeong, Kwang Suk Park
OBJECTIVES: Obstructive sleep apnea (OSA) is a major sleep disorder that causes insufficient sleep, which is linked with daytime fatigue and accidents. Long-term sleep monitoring can provide meaningful information for patients with OSA to prevent and manage their symptoms. Even though various methods have been proposed to objectively measure sleep in ambulatory environments, less reliable information was provided in comparison with standard polysomnography (PSG). Therefore, this paper proposes an algorithm for distinguishing wakefulness from sleep using a patch-type device, which is applicable for both healthy individuals and patients with OSA...
March 2018: Computer Methods and Programs in Biomedicine
Deepika Narasimha, Nader Hanna, Hiroko Beck, Michael Chaskes, Robert Glover, Robert Gatewood, Mohamad Bourji, Gregory D Gudleski, Susan Danzer, Anne B Curtis
INTRODUCTION: Ambulatory cardiac monitoring devices such as external loop recorders (ELRs) are often used in the outpatient clinic to evaluate palpitations. However, ELRs can be bulky and uncomfortable to use, especially in public, at work, or in social situations. An alternative approach is a smartphone-based electrocardiographic (ECG) recorder/event recorder (Kardia Mobile (KM)), but the comparative diagnostic yield of each approach has not been studied. METHODS: Thirty-three patients with palpitations wore an ELR and carried a KM for a period of 14-30 days...
March 1, 2018: Pacing and Clinical Electrophysiology: PACE
Valérie Tikhonoff, Tatiana Kuznetsova, Lutgarde Thijs, Nicholas Cauwenberghs, Katarzyna Stolarz-Skrzypek, Jitka Seidlerová, Sofia Malyutina, Natasza Gilis-Malinowska, Ewa Swierblewska, Kalina Kawecka-Jaszcz, Jan Filipovský, Krzysztof Narkiewicz, Gregory Y H Lip, Edoardo Casiglia, Jan A Staessen
OBJECTIVE: Data on the contribution of ambulatory blood pressure (ABP) components to the risk of developing atrial fibrillation (AF) are limited. We prospectively tested the hypothesis that ABP may represent a potentially modifiable risk factor for the development of AF in a European population study. METHODS: We recorded daytime blood pressure (BP) in 3956 subjects randomly recruited from the general population in five European countries. Of these participants, 2776 (70...
February 9, 2018: Heart: Official Journal of the British Cardiac Society
Victoria A Serhiyenko, Alexandr A Serhiyenko
Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed heart rate (HR) to development of "silent" myocardial infarction. Clinical correlates or risk markers for CAN are age, DM duration, glycemic control, hypertension, and dyslipidemia (DLP), development of other microvascular complications...
January 15, 2018: World Journal of Diabetes
David G Benditt, Wayne O Adkisson, Richard Sutton, Robin K Mears, Scott Sakaguchi
INTRODUCTION: Diagnostic ambulatory ECG (AECG) monitoring is widely used for evaluating syncope and collapse, and practice guidelines provide recommendations regarding optimal AECG device selection. However, whether physicians utilize AECGs in accordance with the pertinent guidelines is unclear. This study assessed utilization of AECG monitoring systems for syncope and collapse diagnosis by physicians in the United States. METHODS AND RESULTS: A quantitative survey was undertaken of physicians comprising multiple specialties (Emergency Room, n = 35; Primary care, n = 35; Hospitalists, n = 30; Neurologists, n = 30; non-implanting, n = 34 and implanting-Cardiologists, n = 35)...
January 4, 2018: Pacing and Clinical Electrophysiology: PACE
Barbara Uznańska-Loch, Kamil Wikło, Ewa Trzos, Karina Wierzbowska-Drabik, Łukasz Chrzanowski, Jarosław Damian Kasprzak, Małgorzata Kurpesa
BACKGROUND: Whether non-invasive electrocardiographic parameters may be of similar relevance in pulmonary arterial hypertension (PAH) as in left ventricular heart failure (LVHF) remains unclear. AIM: To examine a profile of electrocardiographic parameters in PAH and to determine their prognostic significance. Comparison of profile in patients with pulmonary hypertension secondary to left ventricular dysfunction was planned to put PAH group results into context. METHODS: We included 41 patients with type 1...
January 3, 2018: Kardiologia Polska
Paul R Roberts, Donah Zachariah, John M Morgan, Arthur M Yue, Elizabeth F Greenwood, Patrick C Phillips, Philip A Kalra, Darren Green, Robert J Lewis, Paul R Kalra
INTRODUCTION: It has been suggested that sudden cardiac death (SCD) contributes around 50% of cardiovascular and 27% of all-cause mortality in hemodialysis patients. The true burden of arrhythmias and arrhythmic deaths in this population, however, remains poorly characterised. Cardio Renal Arrhythmia Study in Hemodialysis (CRASH-ILR) is a prospective, implantable loop recorder single centre study of 30 established hemodialysis patients and one of the first to provide long-term ambulatory ECG monitoring...
2017: PloS One
Timothy F Simpson, Nora Goldschlager
A 58-year-old male underwent ambulatory ECG monitoring with continuous patch monitoring (Zio XT Patch) for the complaint of episodic dyspnea. In the period of monitoring the patient suffered sudden cardiac death (SCD) with continuous ECG recording showing pronounced ST segment elevations followed by bradycardia and death. This report highlights the growing potential of continuous ST segment monitoring, and features the infrequent entity of ischemic electromechanical dissociation with bradyarrhythmia as a cause of SCD...
October 18, 2017: Journal of Electrocardiology
Matthew A Christensen, Kaylin T Nguyen, Phyllis K Stein, Raymond B Fohtung, Elsayed Z Soliman, Thomas A Dewland, Eric Vittinghoff, Bruce M Psaty, Susan R Heckbert, Gregory M Marcus
BACKGROUND: Blacks have a lower risk of atrial fibrillation (AF) despite having more AF risk factors, but the mechanism remains unknown. Premature atrial contraction (PAC) burden is a recently identified risk factor for AF. OBJECTIVE: The purpose of this study was to determine whether the burden of PACs explains racial differences in AF risk. METHODS: PAC burden (number per hour) was assessed by 24-hour ambulatory electrocardiographic (ECG) monitoring in a randomly selected subset of patients in the Cardiovascular Health Study...
December 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Salah Al-Zaiti, Samir Saba, Rodolfo Pike, Jennifer Williams, Fadi Khraim
BACKGROUND: A prolonged corrected QT (QTc) interval is a known risk factor for adverse cardiac events. Understanding the determinants and physiologic correlates of QTc is necessary for selecting proper strategies to reduce the risk of adverse events in high-risk patients. We sought to evaluate the role of arterial stiffness in heart failure as a determinant of QTc prolongation. METHOD: This was an observational study that recruited ambulatory heart failure patients (New York Heart Association Classes I-II) from an outpatient heart failure clinic...
January 1, 2017: Biological Research for Nursing
Stela Maria Vitorino Sampaio, Neyle Moara Craveiro, Francisco Darrieux, Ítalo Martins de Oliveira, Mauricio Scanavacca, Denise Hachul
Although new pacemakers can register cardiac rhythm, few studies were performed evaluating their accuracy in diagnosing ventricular arrhythmias (VA). This study aimed to assess the correlation and agreement between the pacemaker's monitor and the ambulatory Holter in detecting VA. METHODS/RESULTS: We studied 129 patients with pacemakers, mean age 68.6±19.1 years, 54.8% female. Once Holter monitoring was connected, the pacemakers' event counters were reset and clocks of both systems were synchronized to register ECG simultaneously...
October 24, 2017: Journal of Cardiovascular Electrophysiology
Pratik Singh, S Shahnawazuddin, Gayadhar Pradhan
The primary objective of the presented work is to exploit the power of modified empirical mode decomposition (M-EMD) for the denoising of ECG signals. It is well known that the ECG signals get corrupted by a number of noises during the recording process. Especially, during wireless ECG recording and ambulatory patient monitoring, the signal gets corrupted by additive white Gaussian noise (AWGN). Over the years, several techniques have been proposed for ECG denoising. Among those, empirical mode decomposition (EMD) and nonlocal means (NLM) algorithm are noted to be quite effective...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Bassem Ibrahim, Viswam Nathan, Roozbeh Jafari
In this work we explore the viability of a multimodal sensing device that can be integrated in a wearable form factor for daily, non-invasive ambulatory blood pressure (BP) monitoring. A common approach in previous research has been to rely on measuring the pulse transit time (PTT), which has been shown to be correlated with the BP. In this work, we look into the feasibility of measuring PTT using sensors separated by a small distance on one arm so that any eventual realization of the system is convenient to wear and use over long periods of time...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
M S Kallistratos, L E Poulimenos, A J Manolis
Atrial fibrillation (AF) and arterial hypertension frequently coexist, not only because arterial hypertension increases the incidence of new onset of atrial fibrillation, but also because those two entities share common risk factors and conditions that increase the incidence of both. Thus, in our daily clinical practice we will often have to manage and treat those patients. In order to assess and treat these patients, proper blood pressure (BP) measurement as well as detection of atrial fibrillation is mandatory...
October 18, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Hongyun Liu, Zhao Yang, Fangang Meng, Yuguang Guan, Yanshan Ma, Shuli Liang, Jiuluan Lin, Longsheng Pan, Mingming Zhao, Wei Qu, Hongwei Hao, Guoming Luan, Jianguo Zhang, Luming Li
OBJECTIVE: Epilepsy and seizures can have dramatic effects on the cardiac function. The aim of this study was to investigate the heart rhythm complexity in patients with drug-resistant epilepsy (DRE). METHODS: Ambulatory 24-h electrocardiograms (ECG) from 70 DRE patients and 50 healthy control subjects were analyzed using conventional heart rate variability (HRV) and multiscale entropy (MSE) methods The variation of complexity indices (CI), which was calculated from MSE profile, was determined...
October 5, 2017: Epilepsy Research
Amanda Sarita Cruz Aleixo, Angélica Alfonso, Eunice Oba, Fabiana Ferreira de Souza, Raíssa Karolliny Salgueiro Cruz, Maurício Gianfrancesco Fillippi, Simone Biagio Chiacchio, Miriam Tsunemi, Maria Lucia Gomes Lourenço
Although heart rate (HR) is one of the most important clinical parameters determined via physical examinations, little information is available on the normal HR in dogs, which may be related to the high variability of body weight (BW) in this species. HR is determined by the discharge rate of the sinus node, which is dependent on the autonomic nervous system and the release of catecholamines. The allometric relationship between BW and HR in different species has been described as inversely proportional; however, this relationship has been refuted...
June 2017: Topics in Companion Animal Medicine
Wen-Yi Yang, Blerim Mujaj, Ljupcho Efremov, Zhen-Yu Zhang, Lutgarde Thijs, Fang-Fei Wei, Qi-Fang Huang, Aernout Luttun, Peter Verhamme, Tim S Nawrot, José Boggia, Jan A Staessen
BACKGROUND: The heart ejects in the central elastic arteries. No previous study in workers described the diurnal profile of central blood pressure (BP) or addressed the question whether ECG indexes are more closely associated with central than peripheral BP. METHODS: In 177 men (mean age, 29.1 years), we compared the associations of ECG indexes with brachial and central ambulatory BP, measured over 24 hours by the validated oscillometric Mobil-O-Graph 24h PWA monitor...
September 9, 2017: American Journal of Hypertension
Chang Yan, Peng Li, Lizhen Ji, Lianke Yao, Chandan Karmakar, Changchun Liu
BACKGROUND: Heart rate fluctuates beat-by-beat asymmetrically which is known as heart rate asymmetry (HRA). It is challenging to assess HRA robustly based on short-term heartbeat interval series. METHOD: An area index (AI) was developed that combines the distance and phase angle information of points in the Poincaré plot. To test its performance, the AI was used to classify subjects with: (i) arrhythmia, and (ii) congestive heart failure, from the corresponding healthy controls...
September 21, 2017: Biomedical Engineering Online
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