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https://www.readbyqxmd.com/read/27920853/magnetic-resonance-imaging-of-adenoma-malignum-of-the-uterine-cervix-with-pathologic-correlation-a-case-report
#1
Alba Castán Senar, Blanca Paño, Adela Saco, Carlos Nicolau
Adenoma malignum (AM) is considered a rare subtype of cervical adenocarcinoma. Although previous reports have described magnetic resonance findings, none of these reports evaluated the utility of diffusion-weighted imaging in the differential diagnosis of AM and other multicystic cervical lesions. We present a case report of an AM that did not show restriction on the apparent diffusion coefficient map, which can be explained by the low cellularity of the tumor. This is consistent with the proper correlation between the diffusion imaging and histopathology of the tumor...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27917700/posterior-reversible-encephalopathy-syndrome-following-elevated-mean-arterial-pressures-for-cervical-spinal-cord-injury
#2
Jeffrey H Zimering, Addisu Mesfin
BACKGROUND: Increasing the mean arterial pressure (MAP) is an accepted treatment modality to minimize the risk for irreversible neurologic damage secondary to spinal cord ischemia. Posterior reversible encephalopathy syndrome (PRES) is a rare complication occurring after transplantation surgery, in persons having an autoimmune disorder or after abrupt increases in blood pressure of various etiologies. STUDY DESIGN: Case report. METHODS: Retrospective evaluation of medical records...
December 5, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27917112/reproducibility-and-reliability-of-quantitative-and-weighted-t1-and-t2-%C3%A2-mapping-for-myelin-based-cortical-parcellation-at-7-tesla
#3
Roy A M Haast, Dimo Ivanov, Elia Formisano, Kâmil Uludaǧ
Different magnetic resonance (MR) parameters, such as R1 (=1/T1) or T2(∗), have been used to visualize non-invasively the myelin distribution across the cortical sheet. Myelin contrast is consistently enhanced in the primary sensory and some higher order cortical areas (such as MT or the cingulate cortex), which renders it suitable for subject-specific anatomical cortical parcellation. However, no systematic comparison has been performed between the previously proposed MR parameters, i.e., the longitudinal and transversal relaxation values (or their ratios), for myelin mapping at 7 Tesla...
2016: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/27911811/the-structure-of-the-catechin-binding-site-of-human-sulfotransferase-1a1
#4
Ian Cook, Ting Wang, Mark Girvin, Thomas S Leyh
We are just beginning to understand the allosteric regulation of the human cytosolic sulfotransferase (SULTs) family-13 disease-relevant enzymes that regulate the activities of hundreds, if not thousands, of signaling small molecules. SULT1A1, the predominant isoform in adult liver, harbors two noninteracting allosteric sites, each of which binds a different molecular family: the catechins (naturally occurring flavonols) and nonsteroidal antiinflammatory drugs (NSAIDs). Here, we present the structure of an SULT allosteric binding site-the catechin-binding site of SULT1A1 bound to epigallocatechin gallate (EGCG)...
November 23, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27904982/magnetic-resonance-evaluation-of-cardiac-thrombi-and-masses-by-t1-and-t2-mapping-an-observational-study
#5
Thibault Caspar, Soraya El Ghannudi, Mickaël Ohana, Aïssam Labani, Aubrietia Lawson, Patrick Ohlmann, Olivier Morel, Michel De Mathelin, Catherine Roy, Afshin Gangi, Philippe Germain
The purpose of this work was to evaluate CMR T1 and T2 mapping sequences in patients with intracardiac thrombi and masses in order to assess T1 and T2 relaxometry usefulness and to allow better etiological diagnosis. This observational study of patients scheduled for routine CMR was performed from September 2014 to August 2015. All patients referred to our department for a 1.5 T CMR were screened to participate. T1 mapping were acquired before and after Gadolinium injection; T2 mapping images were obtained before injection...
December 1, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27903537/comprehensive-cardiovascular-magnetic-resonance-assessment-in-patients-with-sarcoidosis-and-preserved-left-ventricular-ejection-fraction
#6
Simon Greulich, Daniel Kitterer, Joerg Latus, Eissa Aguor, Hannah Steubing, Philipp Kaesemann, Alexandru Patrascu, Andreas Greiser, Stefan Groeninger, Agnes Mayr, Niko Braun, M Dominik Alscher, Udo Sechtem, Heiko Mahrholdt
BACKGROUND: Cardiac sarcoidosis (CS) may manifest as arrhythmia or even sudden cardiac death. Because patients with CS often present with nonspecific symptoms, normal electrocardiography, and preserved left ventricular ejection fraction, a reliable diagnostic tool for the work-up of CS is needed. Late gadolinium enhancement-cardiovascular magnetic resonance has proven diagnostic value in CS but has some limitations that may be overcome by adding newer cardiovascular magnetic resonance mapping techniques...
November 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27903187/stereotactic-diffusion-tensor-imaging-tractography-for-gamma-knife-radiosurgery
#7
Cormac G Gavin, H Ian Sabin
OBJECTIVE The integration of modern neuroimaging into treatment planning has increased the therapeutic potential and safety of stereotactic radiosurgery. The authors report their method of integrating stereotactic diffusion tensor imaging (DTI) tractography into conventional treatment planning for Gamma Knife radiosurgery (GKRS). The aim of this study was to demonstrate the feasibility of this technique and to address some of the technical limitations of previously reported techniques. METHODS Twenty patients who underwent GKRS composed the study cohort...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27897393/cancer-anorexia-hypothalamic-activity-and-its-association-with-inflammation-and-appetite-regulating-peptides-in-lung-cancer
#8
Alessio Molfino, Alessandro Iannace, Maria Chiara Colaiacomo, Alessio Farcomeni, Alessandra Emiliani, Gianfranco Gualdi, Alessandro Laviano, Filippo Rossi Fanelli
BACKGROUND: Energy homeostasis is mediated by the hypothalamus, whose inflammation-induced functional derangements contribute to the onset of anorexia in cancer. By using functional magnetic resonance imaging (fMRI), we determined the patterns of hypothalamic activation after oral intake in anorexic (A), non-anorexic (NA) cancer patients, and in controls (C). METHODS: Lung cancer patients were considered. Hypothalamic activation was recorded in A and NA patients and in C by fMRI, before (T0), immediately after (T1) the administration of an oral nutritional supplement, and after 15 min (T2)...
October 5, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27896400/quantitative-assessment-of-the-supraspinatus-tendon-on-mri-using-t2-t2-mapping-and-shear-wave-ultrasound-elastography-a-pilot-study
#9
Konstantin Krepkin, Mary Bruno, José G Raya, Ronald S Adler, Soterios Gyftopoulos
OBJECTIVE: To determine whether there is an association between T2/T2* mapping and supraspinatus tendon mechanical properties as assessed by shear-wave ultrasound elastography (SWE). MATERIALS AND METHODS: This HIPAA-compliant prospective pilot study received approval from our hospital's institutional review board. Eight patients (3 males/5 females; age range 44-72 years) and nine shoulders underwent conventional shoulder MRI, T2/T2* mapping on a 3-T scanner, and SWE...
November 28, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27894068/residual-myocardial-iron-following-intramyocardial-hemorrhage-during-the-convalescent-phase-of-reperfused-st-segment-elevation-myocardial-infarction-and-adverse-left-ventricular-remodeling
#10
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Steven K White, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Manish Ramlall, Ashraf Hamarneh, Alex Sirker, Anna S Herrey, Charlotte Manisty, Derek M Yellon, Peter Kellman, James C Moon, Derek J Hausenloy
BACKGROUND: The presence of intramyocardial hemorrhage (IMH) in ST-segment-elevation myocardial infarction patients reperfused by primary percutaneous coronary intervention has been associated with residual myocardial iron at follow-up, and its impact on adverse left ventricular (LV) remodeling is incompletely understood and is investigated here. METHODS AND RESULTS: Forty-eight ST-segment-elevation myocardial infarction patients underwent cardiovascular magnetic resonance at 4±2 days post primary percutaneous coronary intervention, of whom 40 had a follow-up scan at 5±2 months...
October 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27893652/correlation-between-t2-t2-star-relaxation-time-and-cervical-intervertebral-disc-degeneration-an-observational-study
#11
Minghua Huang, Yong Guo, Qiong Ye, Lei Chen, Kai Zhou, Qingjun Wang, Lixin Shao, Qinglei Shi, Chun Chen
PURPOSE: To demonstrate the potential benefits of T2 relaxation time of intervertebral discs (IVDs) regarding the detection and grading of degenerative disc disease using 3.0-T magnetic resonance imaging (MRI) in a clinical setting. MATERIALS AND METHODS: Cervical sagittal T2-weighted, T2 relaxation MRI was performed at 3.0-T in 61 subjects, covering discs C2-3 to C6-7. All discs were morphologically assessed based on the Pfirrmann grade, and regions of interests (ROIs) were drawn over the T2 mapping...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27893386/optimizing-mr-scan-design-for-model-based-t1-t2-estimation-from-steady-state-sequences
#12
Gopal Nataraj, Jon-Fredrick Nielsen, Jeffrey Fessler
Rapid, reliable quantification of MR relaxation parameters T1 and T2 is desirable for many clinical applications. Steady-state sequences such as Spoiled Gradient-Recalled Echo (SPGR) and Dual-Echo Steady-State (DESS) are fast and wellsuited for relaxometry because the signals they produce are quite sensitive to T1 and T2 variation. However, T1, T2 estimation with these sequences typically requires multiple scans with varied sets of acquisition parameters. This paper describes a systematic framework for selecting scan types (e...
October 4, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27892880/mri-cross-sectional-atlas-of-normal-canine-cervical-musculoskeletal-structure
#13
M Alizadeh, C Zindl, M J Allen, G G Knapik, N Fitzpatrick, W S Marras
Although magnetic resonance imaging (MRI) has been increasingly used as a diagnostic tool for cervical spine injuries in canines, a comprehensive normal MRI anatomy of the canine cervical spine muscles is lacking. Therefore, the purpose of this study was to build a magnetic resonance imaging atlas of the normal cross sectional anatomy of the muscles of the canine cervical spine. MRI scans were performed on a canine cadaver using a combination of T1 and T2-weighted images in the transverse, sagittal and dorsal planes acquired at a slice thickness of 1mm...
September 30, 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/27890445/acute-carbon-monoxide-poisoning-mr-imaging-findings-with-clinical-correlation
#14
D M Kim, I H Lee, J Y Park, S-B Hwang, D S Yoo, C J Song
PURPOSE: To assess the magnetic resonance imaging (MRI) findings, including diffusion-weighted imaging (DWI) in patients with acute carbon monoxide (CO) poisoning and correlate MRI findings with carboxyhemoglobin levels. MATERIALS AND METHODS: The MRI examinations and medical records of seven men with a mean age of 43±16.0years (SD) (range: 25-63 years) with acute CO poisoning were reviewed. MRI examinations were analyzed with respect to lesion location, imaging presentation on T1- and T2-weighted images, and diffusion characteristics on DWI and apparent diffusion coefficient (ADC) maps...
November 24, 2016: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/27890181/imaging-of-vascular-compression-syndromes
#15
REVIEW
Joseph H Donahue, David A Ornan, Sugoto Mukherjee
Trigeminal neuralgia, hemifacial spasm, vestibulocochlear neuralgia and glossopharyngeal neuralgia represent the most common neurovascular compression syndromes. Repeated vascular pulsations at the vulnerable transitional zone of the individual cranial nerves lead to focal axonal injury and demyelination. High-resolution 3-D T2-weighted MR imaging is essential in detecting and mapping neurovascular compression for directed therapy. Knowledge of the specific nerve root exit, the transitional zones, and the adjacent vasculature is critical in proper management...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27888153/three-dimensional-black-blood-t2-mapping-with-compressed-sensing-and-data-driven-parallel-imaging-in-the-carotid-artery
#16
Jianmin Yuan, Ammara Usman, Scott A Reid, Kevin F King, Andrew J Patterson, Jonathan H Gillard, Martin J Graves
PURPOSE: To develop a 3D black-blood T2 mapping sequence with a combination of compressed sensing (CS) and parallel imaging (PI) for carotid wall imaging. MATERIALS AND METHODS: A 3D black-blood fast-spin-echo (FSE) sequence for T2 mapping with CS and PI was developed and validated. Phantom experiments were performed to assess T2 accuracy using a Eurospin Test Object, with different combination of CS and PI acceleration factors. A 2D multi-echo FSE sequence was used as a reference to evaluate the accuracy...
November 22, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27887713/magnetic-resonance-imaging-correlation-to-intraoperative-findings%C3%A2-of-deeply-infiltrative-endometriosis
#17
Traci E Ito, Elias D Abi Khalil, Myles Taffel, Gaby N Moawad
OBJECTIVE: To show characteristics of deeply infiltrative endometriosis (DIE) on magnetic resonance imaging (MRI) and how they correlate with intraoperative findings. DESIGN: Overview of still and dynamic MRI images of four different patients with DIE. We then used videos from their surgeries to highlight the appearance of endometriosis corresponding to these images (educational video). SETTING: University hospital. PATIENT(S): Four different patients with DIE were included in this video...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27886558/optimization-of-sparse-phase-encodings-for-variable-repetition-delay-turbo-spin-echo-tse-t1-measurements-for-preclinical-applications
#18
DongKyu Lee, Sohyun Han, HyungJoon Cho
A variable repetition-delay (TR) spin echo sequence with repeated refocusing pulses, i.e., a variable TR turbo-spin echo (TSE), provides an attractive means of acquiring an accurate T1 map information that is free from gradient echo based artifacts such as magnetic field inhomogeneities particularly for ultra-high field (at 7T and above) preclinical applications. However, the applicability of multi-slice TSE sequences is often limited by signal distortion from T2 relaxation due to echo-train acquisitions for short T2 tissues, inter-slice cross talks and magnetization transfer (MT) from repetitive slice-selective 180° pulse, and extended scan times with multiple TR excitations...
November 10, 2016: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/27885476/does-t2-mapping-of-the-posterior-annulus-fibrosus-indicate-the-presence-of-lumbar-intervertebral-disc-herniation-a-3-0-tesla-magnetic-resonance-study
#19
Alina Messner, David Stelzeneder, Stefan Trattnig, Götz H Welsch, Martina Schinhan, Sebastian Apprich, Martin Brix, Reinhard Windhager, Siegfried Trattnig
PURPOSE: Indicating lumbar disc herniation via magnetic resonance imaging (MRI) T2 mapping in the posterior annulus fibrosus (AF). METHODS: Sagittal T2 maps of 313 lumbar discs of 64 patients with low back pain were acquired at 3.0 Tesla (3T). The discs were rated according to disc herniation and bulging. Region of interest (ROI) analysis was performed on median, sagittal T2 maps. T2 values of the AF, in the most posterior 10% (PAF-10) and 20% of the disc (PAF-20), were compared...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27884018/blood-transfusion-during-radical-chemo-radiotherapy-does-not-reduce-tumour-hypoxia-in-squamous-cell-cancer-of-the-head-and-neck
#20
Liam Welsh, Rafal Panek, Angela Riddell, Kee Wong, Martin O Leach, Mahvash Tavassoli, Durdana Rahman, Maria Schmidt, Tara Hurley, Lorna Grove, Thomas Richards, Dow-Mu Koh, Christopher Nutting, Kevin Harrington, Kate Newbold, Shreerang Bhide
BACKGROUND: Patients with head and neck squamous cell carcinoma (HNSCC) undergoing radical chemo-radiation (CRT) frequently receive transfusion with packed red cells (PRCT) during radiotherapy on the basis that PRCT increases tumour oxygenation and overcomes hypoxia-induced radio-resistance. This is likely to be a significant oversimplification given the fact that tumour hypoxia is the result of several intrinsic and extrinsic factors, including many that are not directly related to serum haemoglobin (Hb)...
November 24, 2016: British Journal of Cancer
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