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T2 mapping

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https://www.readbyqxmd.com/read/29449935/pleomorphic-liposarcoma-of-bone-a-rare-primary-malignant-bone-tumour
#1
G L Tiemeier, J M Brown, S E Pratap, C McCarthy, A Kastrenopoulou, K Bradley, S Wilson, Z Orosz, C L M H Gibbons, U Oppermann, N A Athanasou
Background: Liposarcoma is an extremely rare primary bone sarcoma. Case presentation: We report a case of primary pleomorphic liposarcoma that arose in an 18 year old male in the metaphysis of the left tibia. Plain radiographs showed a partly sclerotic lesion and MR imaging a heterogeneous tumour predominantly isointense on T1- and high-signal on T2-weighted sequences with focal areas of increased T1 signal that suppressed with fat saturation. PET/CT showed marked FDG uptake (SUV = 17...
2018: Clinical Sarcoma Research
https://www.readbyqxmd.com/read/29448816/using-cartilage-mri-t2-mapping-to-analyze-early-cartilage-degeneration-in-the-knee-joint-of-young-professional-soccer-players
#2
Leonie Waldenmeier, Christoph Evers, Michael Uder, Rolf Janka, Frank Friedrich Hennig, Milena Liese Pachowsky, Götz Hannes Welsch
Objective To evaluate and characterize the appearance of articular cartilage in the tibiofemoral joint of young professional soccer players using T2-relaxation time evaluation on magnetic resonance imaging (MRI). Design In this study, we included 57 male adolescents from the youth academy of a professional soccer team. The MRI scans were acquired of the knee joint of the supporting leg. An "early unloading" (minute 0) and "late unloading" (minute 28) T2-sequence was included in the set of images...
February 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29448805/differentiating-skull-base-chordomas-and-invasive-pituitary-adenomas-with-conventional-mri
#3
Ankang Gao, Jie Bai, Jingliang Cheng, Xiao Cheng, Shujian Li, Zanxia Zhang, Yong Zhang
Background It is difficult to distinguish between invasive pituitary adenomas (IPAs) and skull base chordomas based on tumor location and clinical manifestations. Purpose To investigate the value of the apparent diffusion coefficient (ADC), T2-weighted (T2W) imaging, and dynamic contrast enhancement (DCE) in differentiating skull base chordomas and IPAs. Material and Methods Data for 21 patients with skull base chordomas and 27 patients with IPAs involving the paranasal sinus were retrospectively reviewed, and all diagnoses were pathologically confirmed...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29441909/the-effect-of-continuous-perfusion-of-esmolol-on-cardiovascular-risk-in-elderly-patients-undergoing-noncardiac-surgery
#4
X K Zhang, Q Hu, Q H Chen, W X Wang
We evaluated the effect of continuous perfusion of esmolol on cardiovascular risk during curative laparoscopic surgery for gastrointestinal cancer in elderly patients. Sixty patients with gastrointestinal cancer, aged from 60 to 80 years, were divided into an esmolol group (ES, n = 30) and a control group (NS, n = 30). ES patients were treated with esmolol at a dose of 0.3 mg/kg 3 min before tracheal intubation, and received continuous perfusion of esmolol at a dose of 50 μg/kg/min during operation. In NS, esmolol was replaced by saline...
August 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29439122/iron-insensitive-quantitative-assessment-of-subcortical-gray-matter-demyelination-in-multiple-sclerosis-using-the-macromolecular-proton-fraction
#5
V L Yarnykh, E P Krutenkova, G Aitmagambetova, P Repovic, A Mayadev, P Qian, L K Jung Henson, B Gangadharan, J D Bowen
BACKGROUND AND PURPOSE: Fast macromolecular proton fraction mapping is a recent quantitative MR imaging method for myelin assessment. The objectives of this study were to evaluate the macromolecular proton fraction as a measure of demyelination in subcortical GM structures in multiple sclerosis and assess a potential relationship between demyelination and excess iron deposition using the macromolecular proton fraction and T2* mapping. MATERIALS AND METHODS: Macromolecular proton fraction and T2* maps were obtained from 12 healthy controls, 18 patients with relapsing-remitting MS, and 12 patients with secondary-progressive MS using 3T MR imaging...
February 8, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29438746/longitudinal-changes-in-mr-t1%C3%AF-t2-signal-of-meniscus-and-its-association-with-cartilage-t1p-t2-in-acl-injured-patients
#6
Joseph Knox, Valentina Pedoia, Amy Wang, Matthew Tanaka, Gabby B Joseph, Jan Neumann, Thomas M Link, Xiaojuan Li, C Benjamin Ma
OBJECTIVE: To evaluate the longitudinal changes in meniscal T1ρ/T2 signal post-reconstruction in patients with acute anterior cruciate ligament (ACL) injury and to investigate the association with T1ρ/T2 signal in articular knee cartilage. METHOD: In this prospective study, knees of 37 patients with ACL-injury and reconstruction in addition to 13 healthy controls were scanned using magnetic resonance imaging (MRI) T1ρ/T2 mapping. Quantitative analysis of the meniscus was performed in the anterior/posterior horns of lateral/medial meniscus fourteen sub-compartments of cartilage spanning the medial/lateral area of the tibia and femoral condyles...
February 10, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29429407/non-invasive-differentiation-of-idiopathic-inflammatory-myopathy-with-cardiac-involvement-from-acute-viral-myocarditis-using-cardiovascular-magnetic-resonance-imaging-t1-and-t2-mapping
#7
Adrian T Huber, Marine Bravetti, Jérôme Lamy, Tania Bacoyannis, Charles Roux, Alain de Cesare, Aude Rigolet, Olivier Benveniste, Yves Allenbach, Mathieu Kerneis, Philippe Cluzel, Nadjia Kachenoura, Alban Redheuil
BACKGROUND: Idiopathic inflammatory myopathy (IIM) is a group of autoimmune diseases with systemic myositis which may involve the myocardium. Cardiac involvement in IIM, although often subclinical, may mimic clinical manifestations of acute viral myocarditis (AVM). Our aim was to investigate the usefulness of the combined analysis of cardiovascular magnetic resonance (CMR) T1 and T2 mapping parameters measured both in the myocardium and in the thoracic skeletal muscles to differentiate AVM from IIM cardiac involvement...
February 12, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29427986/airway-inflammation-and-inflammatory-biomarkers
#8
Hui Fang Lim, Parameswaran Nair
Severe asthma is a complex disease consisting of different endotypes with different inflammatory and clinicopathological characteristics due to the heterogeneity of immune responses and smooth muscle dysfunction. There is an unmet clinical need to develop and to validate biomarkers that can differentiate between the asthma endotypes and guide clinical management, particularly since the availability of biologicals directed against T2 cytokines. The presence of a "Th2 endotype" is currently assessed in clinical practice using markers, such as eosinophil count in sputum or blood, fraction of exhaled nitric oxide, and immunoglobulin E...
February 2018: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29427612/comparison-of-quantitative-t2-and-adc-mapping-in-the-assessment-of-3-nitropropionic-acid-induced-neurotoxicity-in-rats
#9
Serguei Liachenko, Jaivijay Ramu, Merle G Paule, Joseph Hanig
To assess the relative performance of MRI T2 relaxation and ADC mapping as potential biomarkers of neurotoxicity, a model of 3-nitropropionic acid (NP)-induced neurodegeneration in rats was employed. Male Sprague-Dawley rats received NP (N = 20, 16-20 mg/kg, ip or sc) or saline (N = 6, 2 ml/kg, ip) daily for 3 days. MRI was performed using a 7 tesla system employing quantitative T2 and ADC mapping based on spin echo pulse sequence. All maps were skull stripped and co-registered and the changes were quantified using baseline subtraction and anatomical segmentation...
February 7, 2018: Neurotoxicology
https://www.readbyqxmd.com/read/29426012/mri-ute-t2-profile-characteristics-correlate-to-walking-mechanics-and-patient-reported-outcomes-2-years-after-acl-reconstruction
#10
Ashley A Williams, Matthew R Titchenal, Thomas P Andriacchi, Constance R Chu
OBJECTIVE: Quantitative MRI Ultrashort echo time (UTE) T2* is sensitive to cartilage deep tissue matrix changes after anterior cruciate ligament reconstruction (ACLR). This study was performed to determine whether UTE-T2* profile analyses is a useful clinical metric for assessing cartilage matrix degeneration. This work tests the hypotheses that UTE-T2* depthwise rates of change (profile slopes) correlated with clinical outcome metrics of walking mechanics and patient reported outcomes (PRO) in patients 2 years after ACLR...
February 6, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29422068/early-evaluation-of-radiation-induced-parotid-damage-in-patients-with-nasopharyngeal-carcinoma-by-t2-mapping-and-mdixon-quant-imaging-initial-findings
#11
Nan Zhou, Chen Chu, Xin Dou, Weibo Chen, Jian He, Jing Yan, Zhengyang Zhou, Xiaofeng Yang
BACKGROUND: Radiation-induced parotid damage is a common complication in patients with nasopharyngeal carcinoma (NPC) treated with radiotherapy to head and neck region, which severely reduce the life quality of those patients. The aim of this study was to early evaluate the changes of irradiated parotid glands with T2 mapping and mDIXON Quant imaging. METHODS: Forty-one patients with NPC underwent conventional magnetic resonance imaging for nasopharynx and neck, and T2 mapping and mDIXON Quant imaging for bilateral parotid glands within 2 weeks before radiotherapy (pre-RT), 5 weeks after the beginning of radiotherapy (mid-RT), and 4 weeks after radiotherapy (post-RT)...
February 8, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29415744/correction-to-clinical-recommendations-for-cardiovascular-magnetic-resonance-mapping-of-t1-t2-t2-and-extracellular-volume-a-consensus-statement-by-the-society-for-cardiovascular-magnetic-resonance-scmr-endorsed-by-the-european-association-for-cardiovascular
#12
Daniel R Messroghli, James C Moon, Vanessa M Ferreira, Lars Grosse-Wortmann, Taigang He, Peter Kellman, Julia Mascherbauer, Reza Nezafat, Michael Salerno, Erik B Schelbert, Andrew J Taylor, Richard B Thompson, Martin Ugander, Ruud B van Heeswijk, Matthias G Friedrich
J CARDIOVASC MAGN RESON (2017) 19: 75. DOI: 10.1186/S12968-017-0389-8: In the original publication of this article [1] the "Competing interests" section was incorrect. The original publication stated the following competing interests.
February 7, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29415697/study-protocol-of-a-randomized-controlled-trial-to-test-the-effect-of-a-smartphone-application-on-oral-health-behavior-and-oral-hygiene-in-adolescents-with-fixed-orthodontic-appliances
#13
Janneke F M Scheerman, Berno van Meijel, Pepijn van Empelen, Gem J C Kramer, Gijsbert H W Verrips, Amir H Pakpour, Matheus C T Van den Braak, Cor van Loveren
BACKGROUND: Adolescents with fixed orthodontic appliances are at high risk of developing dental caries. To date, new smartphone technologies have seldom been used to support them in the preventive behavior that can help prevent dental caries. After an intervention-mapping process, we developed a smartphone application (the WhiteTeeth app) for preventing dental caries through improved oral-health behavior and oral hygiene. The app, which is intended to be used at home, will help adolescents with fixed orthodontic appliances perform their oral self-care behavior...
February 7, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29415344/texture-analysis-of-t1-w-and-t2-w-mr-images-allows-a-quantitative-evaluation-of-radiation-induced-changes-of-internal-obturator-muscles-after-radiotherapy-for-prostate-cancer
#14
Elisa Scalco, Tiziana Rancati, Ileana Pirovano, Alfonso Mastropietro, Federica Palorini, Alessandro Cicchetti, Antonella Messina, Barbara Avuzzi, Riccardo Valdagni, Giovanna Rizzo
PURPOSE: To investigate the potential of texture analysis applied on T2-w and post contrast T1-w images acquired before radiotherapy for prostate cancer (PCa) and 12 months after its completion in quantitatively characterizing local radiation effect on the muscular component of internal obturators, as organs potentially involved in urinary toxicity. METHODS: T2-w and post contrast T1-w MR images were acquired at 1.5T before treatment (MRI1) and at 12 months of follow-up (MRI2) in 13 patients treated with radiotherapy for PCa...
February 7, 2018: Medical Physics
https://www.readbyqxmd.com/read/29414162/degradation-of-organophosphate-esters-in-sewage-sludge-effects-of-aerobic-anaerobic-treatments-and-bacterial-community-compositions
#15
Long Pang, Liming Ge, Peijie Yang, Han He, Hongzhong Zhang
In this study, the degradation of organophosphate esters (OPEs) in sewage sludge with aerobic composting and anaerobic digestion was investigated. The total concentrations of six OPEs (ΣOPEs) in the whole treatment process reduced in the order of anaerobic digestion combined with pig manure (T3) > aerobic composting combined with pig manure (T1) > aerobic composting (T2) > anaerobic digestion (T4). The addition of pig manure significantly enhanced the removal rate of OPEs in both aerobic and anaerobic treatments...
January 30, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29411457/changes-in-structural-network-are-associated-with-cortical-demyelination-in-early-multiple-sclerosis
#16
Gabriel Mangeat, Atef Badji, Russell Ouellette, Constantina A Treaba, Elena Herranz, Tobias Granberg, Céline Louapre, Nikola Stikov, Jacob A Sloane, Pierre Bellec, Caterina Mainero, Julien Cohen-Adad
The aim of this study was to investigate the interplay between structural connectivity and cortical demyelination in early multiple sclerosis. About 27 multiple sclerosis patients and 18 age-matched controls underwent two MRI scanning sessions. The first was done at 7T and involved acquiring quantitative T1 and T2 * high-resolution maps to estimate cortical myelination. The second was done on a Connectom scanner and consisted of acquiring high angular resolution diffusion-weighted images to compute white matter structural connectivity metrics: strength, clustering and local efficiency...
February 6, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29411058/diagnostic-performances-of-intravoxel-incoherent-motion-and-conventional-diffusion-weighted-imaging-in-the-differential-diagnosis-of-benign-and-malignant-portal-vein-thrombus
#17
Emel Kaya Aumann, Sadik Server, Bedriye Koyuncu Sokmen, Aysegul Oz, Esat Namal, Nagihan Inan Gurcan, Numan Cem Balci, Yaman Tokat
PURPOSE: To evaluate the diagnostic accuracy of intravoxel incoherent motion (IVIM) and diffusion-weighted imaging (DWI) parameters in the differential diagnosis of portal vein thrombus (PVT). METHODOLOGY: Thirty-five patients with PVT were enrolled in this retrospective study. Precontrast axial in-phase and out-of-phase T1-weighted (W) turbo field echo (TFE), axial and coronal T2-W single-shot turbo spin echo, IVIM with b values between 0 and 1300 s/mm2 and conventional DWI with b factors of 50, 400, and 800 s/mm2 with single-shot echo-planar imaging, and postcontrast dynamic T1-W volumetric interpolated breath-hold examination images obtained with 1...
February 7, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29395552/patellofemoral-cartilage-lesions-treated-with-particulated-juvenile-allograft-cartilage-a-prospective-study-with-minimum-2-year-clinical-and-magnetic-resonance-imaging-outcomes
#18
Tim Wang, Nicole S Belkin, Alissa J Burge, Brenda Chang, Mollyann Pais, Gregory Mahony, Riley J Williams
PURPOSE: To analyze the functional outcomes of patients treated with particulated juvenile articular cartilage (PJAC) for symptomatic articular cartilage lesions in the patellofemoral joint, correlates clinical outcomes with magnetic resonance imaging (MRI) appearance of the repair tissue using cartilage-sensitive quantitative T2-mapping. METHODS: All patients treated with PJAC for patellofemoral lesions were identified and prospectively followed with clinical outcome scores (International Knee Documentation Committee [IKDC], Knee Outcome Survey-Activities of Daily Living [KOS-ADL], and Marx Activity Scale [MAS])...
January 29, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29390547/quantitative-evaluation-of-lumbar-intervertebral-disc-degeneration-by-axial-t2-mapping
#19
Leitao Huang, Yuan Liu, Yi Ding, Xia Wu, Ning Zhang, Qi Lai, Xianjun Zeng, Zongmiao Wan, Min Dai, Bin Zhang
To quantitatively evaluate the clinical value and demonstrate the potential benefits of biochemical axial T2* mapping-based grading of early stages of degenerative disc disease (DDD) using 3.0-T magnetic resonance imaging (MRI) in a clinical setting.Fifty patients with low back pain and 20 healthy volunteers (control) underwent standard MRI protocols including axial T2* mapping. All the intervertebral discs (IVDs) were classified morphologically. Lumbar IVDs were graded using Pfirrmann score (I to IV). The T2* values of the anterior annulus fibrosus (AF), posterior AF, and nucleus pulposus (NP) of each lumbar IVD were measured...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29386458/quantitative-t2-mapping-of-knee-cartilage-comparison-between-the-synthetic-mr-imaging-and-the-cpmg-sequence
#20
Seung Hyun Lee, Young Han Lee, Ho-Taek Song, Jin-Suck Suh
The purpose was to evaluate the feasibility of quantitative MRI T2 mapping based on the quantitative MRI (QRAPMASTER) sequence for the quantitative assessment of knee cartilage. The T2 values from the phantom study showed excellent correlation between the two techniques (r2 = 0.998). The cartilage T2 values exhibited strong correlations (r2 = 0.867-0.982). Quantitative MRI (qMRI) T2 mapping can be used as an alternative to multi-echo T2 mapping, with relatively short scan time.
February 1, 2018: Magnetic Resonance in Medical Sciences: MRMS
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