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T1 mapping

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https://www.readbyqxmd.com/read/28430742/utility-of-single-photon-emission-tomography-computed-tomography-for-sentinel-lymph-node-localization-in-breast-cancer-patients
#1
Agnieszka Giżewska, Ewa Witkowska-Patena, Sebastian Osiecki, Andrzej Mazurek, Zofia Stembrowicz-Nowakowska, Mirosław Dziuk
OBJECTIVES: Sentinel lymph node (SLN) mapping is currently a routine technique in breast cancer management and preoperative scintigraphic imaging plays a crucial role in the process of SLN detection. The guidelines recommend performing planar acquisition and optional single-photon emission tomography/computed tomography (SPECT/CT) imaging. The aim of this study was to verify whether routine performing of SPECT/CT in addition to planar imaging increases the sensitivity of SLN detection in patients with early-stage breast cancer...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28423027/comparison-of-t2-weighted-and-qsm-contrasts-in-parkinson-s-disease-to-visualize-the-stn-with-mri
#2
Anneke Alkemade, Gilles de Hollander, Max C Keuken, Andreas Schäfer, Derek V M Ott, Johannes Schwarz, David Weise, Sonja A Kotz, Birte U Forstmann
The subthalamic nucleus (STN) plays a crucial role in the surgical treatment of Parkinson's disease (PD). Studies investigating optimal protocols for STN visualization using state of the art magnetic resonance imaging (MRI) techniques have shown that susceptibility weighted images, which display the magnetic susceptibility distribution, yield better results than T1-weighted, T2-weighted, and T2*-weighted contrasts. However, these findings are based on young healthy individuals, and require validation in elderly individuals and persons suffering from PD...
2017: PloS One
https://www.readbyqxmd.com/read/28419612/delayed-gadolinium-enhanced-mri-of-cartilage-dgemric-and-t2-mapping-of-talar-osteochondral-lesions-indicators-of-clinical-outcomes
#3
Christoph Rehnitz, Benita Kuni, Felix Wuennemann, Dimitrios Chloridis, Anand Kirwadi, Iris Burkholder, Hans-Ulrich Kauczor, Marc-André Weber
PURPOSE: To evaluate the utility of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) and T2 mapping in evaluation of type II osteochondral lesions (OCLs) of the talus and define cutoff values for identifying patients with good/poor clinical outcomes. MATERIALS AND METHODS: 28 patients (mean age, 42.3 years) underwent T2 mapping and dGEMRIC at least 1.5 years (mean duration, 3.5 years) after microfracture (n = 12) or conservative (n = 16) treatment for type II OCL...
April 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28419591/application-of-spin-echoes-in-the-regime-of-weak-dephasing-to-t1-mapping-of-the-lung
#4
Jakob Assländer, Steffen J Glaser, Jürgen Hennig
PURPOSE: This work presents an approach to mapping the entire lung's proton density and T1 within a single breath-hold and analyzes the apparent T1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition. METHODS: An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequency-pulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting...
April 17, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28418866/investigation-of-hypoxia-conditions-using-oxygen-enhanced-magnetic-resonance-imaging-measurements-in-glioma-models
#5
Qi Fan, Cheuk Ying Tang, Di Gu, Jinyu Zhu, Guojun Li, Yingwei Wu, Xiaofeng Tao
The objective of this study was to determine whether using oxygen-enhanced magnetic resonance imaging (OE-MRI) to assess hypoxia is feasible and whether historical measurements, pO2 changes, and percentage of signal intensity changes (PSIC) are correlated in an animal model of glioma. A total of 25 Sprague-Dawley rats were used to establish C6 brain or subcutaneous glioma model. Nine rats with brain gliomas underwent OE-MRI followed by histopathologic analysis to assess microvessel density and hypoxia. Another 11 rats were underwent OE-MRI and were followed for a survival analysis...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28418811/hypertrabeculated-left-ventricular-myocardium-in-relationship-to-myocardial-function-and-fibrosis-the-multi-ethnic-study-of-atherosclerosis
#6
Nadine Kawel-Boehm, Robyn L McClelland, Filip Zemrak, Gabriella Captur, W Gregory Hundley, Chia-Ying Liu, James C Moon, Steffen E Petersen, Bharath Ambale-Venkatesh, João A C Lima, David A Bluemke
Purpose To determine if excess greater left ventricle (LV) trabeculation is associated with decreased average regional myocardial function, diffuse fibrosis, or both. Materials and Methods This was a HIPAA-compliant institutional board approved multicenter study, and all participants provided written informed consent. Participants in the Multi-Ethnic Study of Atherosclerosis (MESA) underwent a comprehensive cardiac magnetic resonance (MR) examination. LV trabeculation was measured with the maximal apical fractal dimension (FD), which is a marker of endocardial complexity...
April 17, 2017: Radiology
https://www.readbyqxmd.com/read/28414870/three-dimensional-skeletal-mandibular-changes-associated-with-herbst-appliance-treatment
#7
B Q Souki, P L C Vilefort, D D Oliveira, I Andrade, A C Ruellas, M S Yatabe, T Nguyen, L Franchi, J A McNamara, L H S Cevidanes
OBJECTIVES: Three-dimensional evaluation of skeletal mandibular changes following Herbst appliance treatment. SETTING AND SAMPLE POPULATION: Retrospective case-control study, based on a sample size calculation. Twenty-five pubertal patients treated with Herbst appliance (HAG), and 25 matched Class II patients who received other non-orthopaedic dental treatments (CG). MATERIAL AND METHODS: Three-dimensional models were generated from pre-treatment (T0) and post-treatment (T1) cone beam computed tomograms...
May 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28412435/cmr-derived-extracellular-volume-fraction-as-a-marker%C3%A2-for-myocardial-fibrosis-the-importance-of-coexisting-myocardial-inflammation
#8
Julia Anna Lurz, Christian Luecke, David Lang, Christian Besler, Karl-Philipp Rommel, Karin Klingel, Reinhard Kandolf, Volker Adams, Katharina Schöne, Gerhard Hindricks, Gerhard Schuler, Axel Linke, Holger Thiele, Matthias Gutberlet, Philipp Lurz
OBJECTIVES: The aim of the present study was to evaluate whether extracellular volume fraction (ECV) can reliably inform on the extent of diffuse fibrosis in the simultaneous presence of myocardial inflammation, which has not been verified to date. BACKGROUND: Diffuse myocardial fibrosis is associated with unfavorable outcome in patients with cardiomyopathy, and is of prognostic relevance. Assessment of ECV bears promise for being a noninvasive surrogate parameter, but it may be altered by other pathologies...
April 7, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28412429/myocardial-inflammation-an-important-pitfall-during-cmr-t1-mapping-for-the-quantification-of-diffuse-fibrosis-in-heart%C3%A2-failure
#9
EDITORIAL
Julia Mascherbauer
No abstract text is available yet for this article.
April 7, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28411394/improved-magnetic-resonance-fingerprinting-reconstruction-with-low-rank-and-subspace-modeling
#10
Bo Zhao, Kawin Setsompop, Elfar Adalsteinsson, Borjan Gagoski, Huihui Ye, Dan Ma, Yun Jiang, P Ellen Grant, Mark A Griswold, Lawrence L Wald
PURPOSE: This article introduces a constrained imaging method based on low-rank and subspace modeling to improve the accuracy and speed of MR fingerprinting (MRF). THEORY AND METHODS: A new model-based imaging method is developed for MRF to reconstruct high-quality time-series images and accurate tissue parameter maps (e.g., T1 , T2 , and spin density maps). Specifically, the proposed method exploits low-rank approximations of MRF time-series images, and further enforces temporal subspace constraints to capture magnetization dynamics...
April 15, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28401643/ultrafast-compartmentalized-relaxation-time-mapping-with-linear-algebraic-modeling
#11
Yi Zhang, Xiaoyang Liu, Jinyuan Zhou, Paul A Bottomley
PURPOSE: To dramatically accelerate compartmental-average longitudinal (T1 ) and transverse (T2 ) relaxation measurements using the minimal-acquisition linear algebraic modeling (SLAM) method, and to validate it in phantoms and humans. METHODS: Relaxation times were imaged at 3 Tesla in phantoms, in the abdomens of six volunteers, and in six brain tumor patients using standard inversion recovery and multi-spin-echo sequences. k-space was fully sampled to provide reference T1 and T2 measurements, and SLAM was performed using a limited set of phase encodes from central k-space...
April 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28398559/inflammatory-bowel-disease-and-myocarditis-t1-mapping-the-heart-of-the-problem
#12
Elliott J Carande, Stefan K Piechnik, Saul G Myerson, Vanessa M Ferreira
No abstract text is available yet for this article.
April 6, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28396918/comparison-of-10-and-20-min-hepatobiliary-phase-images-on-gd-eob-dtpa-enhanced-mri-t1-mapping-for-liver-function-assessment-in-clinic
#13
Zhi-Peng Zhou, Li-Ling Long, Wei-Jia Qiu, Ge Cheng, Li-Juan Huang, Teng-Fei Yang, Zhong-Kui Huang
PURPOSE: To compare hepatobiliary phase (HBP) images obtained 10 and 20 min after Gd-EOB-DTPA-enhanced MRI for liver function assessment in clinic on 3.0 T MR imaging. METHODS: 103 patients were separated into four groups: 38 patients for the normal liver function (NLF) group, 33 patients for the liver cirrhosis with Child-Pugh A (LCA) group, 21 patients for the liver cirrhosis with Child-Pugh B group, and 11 patients for a liver cirrhosis with Child-Pugh C group...
April 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28388076/immunopet-imaging-of-ctla-4-expression-in-mouse-models-of-non-small-cell-lung-cancer
#14
Emily B Ehlerding, Christopher G England, Rebecca L Majewski, Hector F Valdovinos, Dawei Jiang, Glenn Liu, Douglas G McNeel, Robert J Nickles, Weibo Cai
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is expressed on the surface of activated T cells and some tumor cells, and is the target of the clinically approved monoclonal antibody ipilimumab. In this study, we investigate specific binding of radiolabeled ipilimumab to CTLA-4 expressed by human non-small cell lung cancer cells in vivo using positron emission tomography (PET). Ipilimumab was radiolabeled with (64)Cu (t1/2 = 12.7 h) through the use of the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) to formulate (64)Cu-DOTA-ipilimumab...
April 12, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28384170/differentiation-of-pseudoprogression-and-real-progression-in-glioblastoma-using-adc-parametric-response-maps
#15
Caroline Reimer, Katerina Deike, Markus Graf, Peter Reimer, Benedikt Wiestler, Ralf Omar Floca, Philipp Kickingereder, Heinz-Peter Schlemmer, Wolfgang Wick, Martin Bendszus, Alexander Radbruch
PURPOSE: The purpose of this study was to investigate whether a voxel-wise analysis of apparent diffusion coefficient (ADC) values may differentiate between progressive disease (PD) and pseudoprogression (PsP) in patients with high-grade glioma using the parametric response map, a newly introduced postprocessing tool. METHODS: Twenty-eight patients with proven PD and seven patients with PsP were identified in this retrospective feasibility study. For all patients ADC baseline and follow-up maps on four subsequent MRIs were available...
2017: PloS One
https://www.readbyqxmd.com/read/28376820/blood-correction-reduces-variability-and-gender-differences-in-native-myocardial-t1-values-at-1-5%C3%A2-t-cardiovascular-magnetic-resonance-a-derivation-validation-approach
#16
Jannike Nickander, Magnus Lundin, Goran Abdula, Peder Sörensson, Stefania Rosmini, James C Moon, Peter Kellman, Andreas Sigfridsson, Martin Ugander
BACKGROUND: Myocardial native T1 measurements are likely influenced by intramyocardial blood. Since blood T1 is both variable and longer compared to myocardial T1, this will degrade the precision of myocardial T1 measurements. Precision could be improved by correction, but the amount of correction and the optimal blood T1 variables to correct with are unknown. We hypothesized that an appropriate correction would reduce the standard deviation (SD) of native myocardial T1. METHODS: Consecutive patients (n = 400) referred for CMR with known or suspected heart disease were split into a derivation cohort for model construction (n = 200, age 51 ± 18 years, 50% male) and a validation cohort for assessing model performance (n = 200, age 48 ± 17 years, 50% male)...
April 5, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28376285/impact-of-denoising-on-precision-and-accuracy-of-saturation-recovery-based-myocardial-t1-mapping
#17
Aurélien Bustin, Pauline Ferry, Andrei Codreanu, Marine Beaumont, Shufang Liu, Darius Burschka, Jacques Felblinger, Anja C S Brau, Anne Menini, Freddy Odille
PURPOSE: To evaluate the impact of a novel postprocessing denoising technique on accuracy and precision in myocardial T1 mapping. MATERIALS AND METHODS: This study introduces a fast and robust denoising method developed for magnetic resonance T1 mapping. The technique imposes edge-preserving regularity and exploits the co-occurence of spatial gradients in the acquired T1 -weighted images. The proposed approach was assessed in simulations, ex vivo data and in vivo imaging on a cohort of 16 healthy volunteers (12 males, average age 39 ± 8 years, 62 ± 9 bpm) both in pre- and postcontrast injection...
April 4, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28376231/international-psychometric-validation-of-an-eortc-quality-of-life-module-measuring-cancer-related-fatigue-eortc-qlq-fa12
#18
Joachim Weis, Krzysztof A Tomaszewski, Eva Hammerlid, Juan Ignacio Arraras, Thierry Conroy, Anne Lanceley, Heike Schmidt, Markus Wirtz, Susanne Singer, Monica Pinto, Mohamed Alm El-Din, Inge Compter, Bernhard Holzner, Dirk Hofmeister, Wei-Chu Chie, Marek Czeladzki, Amelie Harle, Louise Jones, Sabrina Ritter, Hans-Henning Flechtner, Andrew Bottomley
Background: The European Organisation for Research and Treatment of Cancer (EORTC) Group has developed a new multidimensional instrument measuring cancer-related fatigue to be used in conjunction with the quality of life core questionnaire (EORTC QLQ-C30). The module EORTC QLQ-FA13 assesses physical, cognitive, and emotional aspects of cancer-related fatigue. Methods: The methodology follows the EORTC guidelines for phase IV validation of modules. This paper focuses on the results of the psychometric validation of the factorial structure of the module...
May 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28373647/fibrosis-quantification-in-hypertensive-heart-disease-with-lvh-and-non-lvh-findings-from-t1-mapping-and-contrast-free-cardiac-diffusion-weighted-imaging
#19
Lian-Ming Wu, Rui Wu, Yang-Rongzheng Ou, Bing-Hua Chen, Qiu-Ying Yao, Qing Lu, Jiani Hu, Meng Jiang, Dong-Aolei An, Jian-Rong Xu
This study assessed the extent of fibrosis and the relationship between the ADC value and systolic strain in hypertensive patients with left ventricular hypertrophy (HTN LVH) and hypertensive patients without LVH (HTN non-LVH) using cardiac diffusion-weighted imaging and T1 mapping. T1 mapping was performed in 13 HTN LVH (mean age, 56.23 ± 3.30 years), 17 HTN non-LVH (mean age, 56.41 ± 2.78 years), and 12 normal control subjects (mean age, 55.67 ± 3.08 years) with 3.0 T MRI using cardiac diffusion-weighted imaging and T1 mapping...
April 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28364177/magnetic-resonance-imaging-for-characterizing-myocardial-diseases
#20
REVIEW
Maythem Saeed, Hui Liu, Chang-Hong Liang, Mark W Wilson
The National Institute of Health defined cardiomyopathy as diseases of the heart muscle. These myocardial diseases have different etiology, structure and treatment. This review highlights the key imaging features of different myocardial diseases. It provides information on myocardial structure/orientation, perfusion, function and viability in diseases related to cardiomyopathy. The standard cardiac magnetic resonance imaging (MRI) sequences can reveal insight on left ventricular (LV) mass, volumes and regional contractile function in all types of cardiomyopathy diseases...
March 31, 2017: International Journal of Cardiovascular Imaging
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