Ashley Tippett, Gabby Ess, Laila Hussaini, Olivia Reese, Luis Salazar, Mary Kelly, Meg Taylor, Caroline Ciric, Amy Keane, Andrew Cheng, Theda Gibson, Wensheng Li, Hui-Mien Hsiao, Laurel Bristow, Kieffer Hellmeister, Zayna Al-Husein, Robin Hubler, Elizabeth Begier, Qing Liu, Bradford Gessner, David L Swerdlow, Satoshi Kamidani, Carol Kao, Inci Yildirim, Nadine Rouphael, Christina A Rostad, Evan J Anderson
BACKGROUND: Data are limited about influenza vaccine effectiveness (VE) in the prevention of influenza-related hospitalizations in older adults and those with underlying high-risk comorbidities. METHODS: We conducted a prospective test-negative case-control study at two US hospitals from October 2018-March 2020 among adults ≥50 years of age hospitalized with acute respiratory illnesses (ARIs) and adults ≥18 years admitted with congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD) exacerbations...
November 8, 2023: Clinical Infectious Diseases